Generic Quality Of Life Inventory Research Articles

Phacoemulsification Plus Intraocular Lens Implantation with Gold Nanoparticles for Complicated Cataract Secondary to Uveitis: Efficacy Analysis

This study analyzes the efficacy of phacoemulsification (PE) plus intraocular lens implantation (IOLI) in patients with complicated cataracts secondary to uveitis. Nanostructured photothermal ring integrated (nano)-intraocular lens (IOLs) were developed to improve the biocompatibility and optical properties of IOLs. However, data on the safety profile and effectiveness of IOLI for patients with complicated cataracts secondary to uveitis are scarce, and studies have questioned the safety of PE in patients undergoing cataract surgery. We used gold nanoparticle (AuNP)-modified commercially available intraocular IOLs combined with PE technology to treat patients with complicated cataracts secondary to uveitis. First, we found that AuNP-modified IOLs were effective in reducing macrophage and bacterial adhesion and were biocompatible with the organism. Then, 64 patients with complicated cataracts secondary to uveitis were totally selected from February 2019 to February 2022, of which 33 cases were treated with PE+IOLI (test group) and 31 with conventional small-incision extracapsular cataract extraction (SIECCE) and IOLI (control group). Intergroup comparisons based on efficacy, safety, visual acuity (VA), aqueous humor protein levels before and after treatment, and quality of life (assessed with the Generic Quality of Life Inventory-74, GQOLI-74) revealed higher overall treatment efficacy and postoperative VA, as well as lower complication rate and postoperative aqueous humor protein levels, in the test group than the control group. Moreover, the test group had higher GQOLI-74 scores in the dimensions of physical function, mental health, psychological health, and social competence than the control group. Thus, PE+IOLI is more suitable for patients with complicated cataracts secondary to uveitis than conventional SIECCE+IOLI. PE+IOLI can improve treatment efficacy and safety, as well as patient VA and quality of life.

Investigation on the alleviating effect of standardized three-step nursing on perioperative pressure injury in patients with spinal fracture accompanied by spinal cord injury

Objective To explore the alleviating effect of standardized three-step nursing on perioperative pressure injury in patients with spinal fractures accompanied by spinal cord injury. Methods A retrospective analysis was conducted on the clinical data of 153 patients who underwent surgical treatment for spinal fracture accompanied by spinal cord injury in our hospital from January 2021 to January 2024. All patients met the criteria for inclusion and exclusion. According to the nursing interventions received during the perioperative period, the patients were divided into a control group (n = 76) and an observation group (n = 77). The control group received routine nursing interventions during the perioperative period, while the observation group received standardized three-step nursing interventions. The occurrence, severity, area, and pain [Visual Analog Scale (VAS)], coagulation indicators [prothrombin time (PT), fibrinogen (FIB), D-dimer (D-D)], activities of daily living [Barthel Index], and quality of life [General Quality of Life Inventory (GQOLI-74)] were compared between the two groups. Results (1) Occurrence and severity of perioperative pressure injury: in the control group, 18 cases of pressure injury occurred, including 5 cases of stage I, 11 cases of stage II, and 2 cases of stage III; in the observation group, 7 cases of pressure injury occurred, including 4 cases of stage I and 3 cases of stage II. The occurrence rate and severity of pressure injury in the observation group were lower than those in the control group (p < 0.05). (2) Area of injury and pain: The area of injury on the day of surgery and 5 days after surgery in the observation group was lower than that in the control group (p < 0.05); the VAS score 5 days after surgery in the observation group was lower than that in the control group (p < 0.05). (3) Coagulation indicators: 5 days after surgery, the levels of D-D and FIB in the observation group were lower than those in the control group, while PT was higher than that in the control group (p < 0.05). (4) Activities of daily living and quality of life: 3 months after surgery, the Barthel score and GQOLI-74 score in the observation group were higher than those in the control group (p < 0.05). Conclusion Standardized three-step nursing can significantly reduce the occurrence rate, severity, and area of perioperative pressure injury in patients with spinal fracture accompanied by spinal cord injury, alleviate patient pain, improve coagulation function, and enhance levels of activities of daily living and quality of life.

Efficacy of transjugular intrahepatic portosystemic shunts in treating cirrhotic esophageal-gastric variceal bleeding.

Esophageal-gastric variceal bleeding (EGVB) represents a severe complication among patients with cirrhosis and often culminates in fatal outcomes. Interventional therapy, a rapidly developing treatment modality over the past few years, has found widespread application in clinical practice due to its minimally invasive characteristics. However, whether transjugular intrahepatic portosystemic shunt (TIPS) treatment has an impact on patient prognosis remains controversial. To probing the efficacy of TIPS for treating cirrhotic EGVB and its influence on the prognosis of patients afflicted by this disease. A retrospective study was conducted on ninety-two patients presenting with cirrhotic EGVB who were admitted to our hospital between September 2020 and September 2022. Based on the different modes of treatment, the patients were assigned to the study group (TIPS received, n = 50) or the control group (percutaneous transhepatic varices embolization received, n = 42). Comparative analyses were performed between the two groups preoperatively and one month postoperatively for the following parameters: Varicosity status; hemodynamic parameters [portal vein flow velocity (PVV) and portal vein diameter (PVD); platelet count (PLT); red blood cell count; white blood cell count (WBC); and hepatic function [albumin (ALB), total bilirubin (TBIL), and aspartate transaminase (AST)]. The Generic Quality of Life Inventory-74 was utilized to assess quality of life in the two groups, and the 1-year postoperative rebleeding and survival rates were compared. Following surgical intervention, there was an improvement in the incidence of varicosity compared to the preoperative status in both cohorts. Notably, the study group exhibited more pronounced enhancements than did the control group (P < 0.05). PVV increased, and PVD decreased compared to the preoperative values, with the study cohort achieving better outcomes (P < 0.05). PLT and WBC counts were elevated postoperatively in the two groups, with the study cohort displaying higher PLT and WBC counts (P < 0.05). No differences were detected between the two groups in terms of serum ALB, TBIL, or AST levels either preoperatively or postoperatively (P < 0.05). Postoperative scores across all dimensions of life quality surpassed preoperative scores, with the study cohort achieving higher scores (P < 0.05). At 22.00%, the one-year postoperative rebleeding rate in the study cohort was significantly lower than that in the control group (42.86%; P < 0.05); conversely, no marked difference was observed in the 1-year postoperative survival rate between the two cohorts (P > 0.05). TIPS, which has demonstrated robust efficacy in managing cirrhotic EGVB, remarkably alleviates varicosity and improves hemodynamics in patients. This intervention not only results in a safer profile but also contributes significantly to a more favorable prognosis.

Long-hair follicular unit excision enhances the cosmetic results of hairline restoration: A retrospective study in Chinese recipients.

Long-hair follicular unit excision (LHF) is gaining popularity, especially for hairline restoration, because it helps avoid hair removal in the donor area and provides better immediate postoperative results. This study aimed to assess the postoperative clinical outcomes of LHF for hairline restoration. Data from 248 patients (223 women and 25 men) who underwent hairline restoration with LHF between September 2018 and June 2022 were analyzed, and they were followed up immediately and 9 months postoperatively. The complications and survival rate of long-hair grafts were assessed. Patient postoperative satisfaction was assessed using a 5-Point Likert Scale. The Generic Quality of Life Inventory-74 (GQOLI-74) assessed the quality of the postoperative life. The planned extraction density was set at 15-25 FU/cm2. The mean number of total extracted hair grafts, transection rate in the extraction area, and extraction time were 1970 ± 124 FU, 3.9 ± 0.2%, and 3.2 ± 0.8 h, respectively. The hairline implantation density was set at 50-70 FU/cm2. The mean number of total transplanted hair grafts was 2031 ± 371 FU; the implant time was 3.8 ± 1.9 h. No serious complications occurred within 7 days postoperatively. The mean graft survival rate was 93.1 ± 1.3% at 9 months postoperatively. All patients were satisfied with the immediate postoperative results, and most were satisfied with the 9-month outcomes (mean overall satisfaction score: 4.7). The scores of physical function, psychological function, social function and material life function after operation were higher than those before operation (p < 0.0001). Hairline restoration with LHF could enhance the cosmetic outcomes and be widely used in clinical practice.

Development and evaluation of an early rehabilitation nursing program for patients with pulmonary tuberculosis.

To develop and evaluate an early rehabilitation nursing program for patients with pulmonary tuberculosis to improve their exercise endurance, pulmonary function, and self-care ability, promote their rehabilitation, improve their quality of life, and explore the construction and application of early rehabilitation nursing program. From March 2021 to August 2022, 104 patients with pulmonary tuberculosis in the improvement stage were recruited and randomly assigned to an intervention group (n = 52) and a control group (n = 52). Exercise endurance was assessed before and 12 weeks after the nursing program, and the groups were compared. Changes in pulmonary function were also analyzed. The exercise of self-care agency scale, self-rating depression scale, self-rating anxiety scale, and generic quality of life inventory-74 were used to assess differences in patients' quality of life. Patients in the intervention group performed significantly better than those in the control group in the 6-minute walking test, and had significantly higher arterial blood oxygen partial pressure and significantly lower arterial partial pressure of carbon dioxide after the intervention (P < .001). After the intervention, the forced vital capacity and forced expiratory volume in 1 second in the intervention group were significantly higher than those in the control group (P < .001). After the intervention, the scores for health knowledge (P < .001), self-care skills (P = .001), self-concept (P < .001) and self-care responsibility (P = .002) of patients in the intervention group were significantly higher, and the self-rating depression scale, self-rating anxiety scale, and generic quality of life inventory-7 scores were significantly lower in the intervention group than in the control group (P < .001). This study demonstrates the clinical value of early rehabilitation nursing during the improvement period in patients with pulmonary tuberculosis.

Clinical study on tri-tongue acupuncture combined with low-frequency electrical stimulation for treating post-stroke dysarthria.

Few studies have investigated low-frequency electrical stimulation combined with tri-tongue acupuncture for the treatment of post-stroke dysarthria. This randomized clinical study assessed the correlation between the clinical efficacy of low-frequency electrical stimulation combined with tri-tongue acupuncture in patients with post-stroke dysarthria. To investigate the clinical effects of tri-tongue acupuncture combined with low-frequency electrical stimulation for treating post-stroke dysarthria. Ninety patients with post-stroke dysarthria, who were admitted to our hospital from December 2019 to June 2021, were selected and equally divided into two groups (n = 45/group) according to the random number table method. Tri-tongue acupuncture was administered in the control group. The treatment group received both tri-tongue acupuncture and low-frequency electrical stimulation. The clinical efficacy, Western Aphasia Battery (WAB) score, general quality of life inventory (GQOLI-74) score, Frenchay Dysarthria Assessment score, and speech function grades were compared and analyzed between both groups. The overall efficacy in the treatment group was better than that in the control group (P < 0.05). Before treatment, the WAB, Frenchay Dysarthria Assessment, or GQOLI-74 scores (P > 0.05) did not differ between the groups. After therapy, the WAB, Frenchay Dysarthria Assessment, and GQOLI-74 scores in both groups increased significantly (P < 0.05), and the treatment group exhibited a significantly greater increase than that of the controls (P < 0.05). Moreover, the classification of speech function did not differ between the two groups before treatment (P > 0.05), whereas significant improvements were observed in both groups after treatment (P < 0.05). The degree of improvement in the treatment group was greater than that in the control group (P < 0.05). Low-frequency electrical stimulation, in conjunction with tri-tongue acupuncture, exhibits a good clinical effect on post-stroke dysarthria.

Application of Early Multi-dimensional Cardiac Rehabilitation Nursing in Percutaneous Coronary Intervention and Its Effects on Adverse Events and Patients’ Adherence to Medication

Objective: To evaluate the application value of early multi-dimensional cardiac rehabilitation nursing in percutaneous coronary intervention (PCI) and its effects on adverse events and patients’ adherence to medication. Methods: A total of 90 patients that underwent PCI in our hospital from January 2019 to January 2020 were selected as the study subjects. The patients were divided into two groups according to the order of admission, the control group and the study group, with 45 patients in each group. Patients in the control group were cared for using conventional nursing methods, while those in the study group were cared for using conventional nursing methods combined with early multi-dimensional cardiac rehabilitation nursing. The efficacy of nursing and the incidence of adverse events in the two groups of patients were assessed and compared. The exercise of self care agency scale (ESCA) was used to evaluate the self-care ability of patients after intervention. The generic quality of life inventory-74 (GQOLI-74) was used to assess the patients’ quality of life after intervention. The Morisky medication adherence scale 9 (MMAS-8) was used to assess the patients’ adherence to medication before and after intervention. The hospital anxiety and depression scale (HAD) was used to assess the patients’ emotional state before and after intervention. Results: The total nursing satisfaction after intervention in the study group was significantly higher than that in the control group (P&lt;0.05). A remarkably lower incidence of adverse cardiovascular events after intervention was observed in the study group in comparison to the control group (P&lt;0.05). Patients in the study group had significantly higher ESCA, GQOLI-74 and MMAS-8 scores and lower HAD scores than those in the control group (all P&lt;0.001). Conclusion: Early multi-dimensional cardiac rehabilitation nursing for patients undergoing PCI can significantly improve the patients’ adherence to medication and quality of life. It can also reduce the incidence of adverse cardiovascular events. It has remarkable nursing efficacy, and is worthy of more widespread promotion and clinical application.

CLINICAL EFFECT OF ENDOSCOPIC TITANIUM CLIPS COMBINED WITH TISSUE ADHESIVE IN THE TREATMENT OF GOV2 GASTRIC FUNDAL VARICES

Objective: To analyze the effect of endoscopic titanium clips combined with tissue adhesive in treating GOV2 (Type 2 Gastroesophageal Varices) patients. Methods: One-hundred-and-seventeen GOV2 patients from June 2018 to June 2020 were divided into the observation group ([Formula: see text]) and control group ([Formula: see text]). The observation group was treated with endoscopic titanium clip combined with the tissue adhesive, while controls were treated with tissue adhesive alone. The clinical effects were compared at 1, 6, and 24 months. Results: Overall response rates of the observation group at 1, 6, and 24 months were 98.31%, 96.61%, and 91.53%, respectively, vs. 81.03%, 76.27%, and 55.17% in controls ([Formula: see text]). The number, diameters, red color sign proportion of varicose veins, and incidence of bleeding in the observation group were lower than the control group, and the GQOL-74 (Generic Quality of Life Inventory 74) score was higher at 1, 6, and 24 months ([Formula: see text]). There was no significant difference in complications, mortality at 6 and 24 months, and recurrence rate at 6 months ([Formula: see text]); however, the recurrence rate at 24 months after treatment was lower in the observation group (6.78% vs. 20.69%) ([Formula: see text]). Conclusions: Endoscopic titanium clips combined with tissue adhesive can be applied to treat GOV2 patients.

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PREFACE

Effect of Nursing Outcome-Oriented Intervention on Airway Management in Elderly Long-Term Bedridden Patients.

Objective This study intended to explore the nursing outcome-oriented intervention's effect on airway management in elderly long-term bedridden patients. Methods A total of 120 cases of elderly long-term bedridden patients admitted to our hospital from May 2018 to June 2020 were enrolled and randomly divided into the observation group (n = 60) and control group (n = 60). The control group received the routine nursing intervention, while the observation group received the nursing outcome-oriented intervention. Forced expiratory volume (FEV1), forced vital capacity (FVC), and maximal voluntary ventilation (MVV) in the first second were compared between the two groups before and after the intervention. The pulmonary infection of the two groups was observed. Total protein, hemoglobin, albumin, and cholesterol levels were compared between the two groups. Hamilton Anxiety Scale (HAMA) and Hamilton Depression Scale (HAMD) were used to evaluate the two groups' psychological status before and after the intervention. The Generic Quality of Life Inventory-74 (GQOLI-74) assessed the two groups' quality of life. Results After the intervention, the levels of FEV1, FVC, and MVV; total protein, hemoglobin, albumin, and cholesterol; and scores of physical function, psychological function, social function, and material life function in the observation group were higher than those in the control group. Pulmonary infection, secondary infection, the infection rate is more than 3%, HAMA, and HAMD scores, and the incidence of pressure ulcers, aspiration, constipation, and the falling bed was lower than those in the control group, with statistical significance (all P < 0.05). Conclusion Nursing outcome-oriented intervention can effectively improve lung function, pulmonary infection, nutritional status, negative mood, and quality of life of long-term bedridden elderly patients.

Application Value of Management Model Based on "Zero Tolerance" Concept in Pressure Ulcer Management.

Background Pressure injuries are the most prevalent health problem worldwide. Improving the quality of hospital pressure injury management is an important indicator to improve the quality of hospital management. Objective To explore the application value of the management model centered on the concept of “zero tolerance” in the management of pressure ulcers (PU). Methods The effects of conventional management mode and management mode centered on the concept of “zero tolerance” on PU patients and nursing staff were retrospectively analyzed. The patients were evaluated by the general comfort questionnaire (GCQ), Generic Quality of Life Inventory 74 (GQOL-74), and pressure ulcer healing scale (PUSH). At the same time, the satisfaction of PU patients and nursing staff with different management modes was investigated. Results When comparing the conditions of patients under different management modes, it was found that the “zero tolerance” management mode can improve the comfort and quality of life of patients during hospitalization. Compared with the conventional management mode, the “zero tolerance” management mode can significantly improve the degree of pressure ulcer healing in patients. In addition, the “zero tolerance” management model can not only improve the satisfaction of patients with management but also improve the satisfaction of nursing staff with management. Conclusion Standardized management of PU patients with the concept of “zero tolerance” as the core can improve the health status and quality of life of patients, promote wound healing, and improve the satisfaction of patients and nurses with the management plan.

The Effect of Computer-Assisted Cognitive Remediation Therapy on Cognitive Function, Social Function and Quality of Life in Patients with Vascular Dementia.

Our study aimed to investigate the effects of computer-assisted cognitive remediation therapy (CCRT) on cognitive function, social function and quality of life in patients with vascular dementia (VD). Ninety-eight patients with VD were treated with CCRT in four 45-minute sessions per week over a course of 40 sessions to exercise four cognitive functions, including flexibility, working memory, plan execution and social cognition. The Mini-Mental State Examination (MMSE), Social Disability Screening Schedule (SDSS), Personal and Social Performance Scale (PSP), and Generic Quality of Life Inventory-74 (GQOL-74) were used to assess before and after treatment. (1) The scores of orientation (5.60 ± 1.35), calculation (2.20 ± 0.79), verbal ability (7.10 ± 0.36), spatial ability (0.78 ± 0.42), immediate memory (2.42 ± 0.53), short-term memory (1.17 ± 0.78) and MMSE (23.36 ± 2.98) were all improved after treatment (P < 0.05) compared with those before treatment; (2) The scores of SDSS, PSP and Activities of Daily Living (ADL) after treatment were 8.23 ± 0.94, 81.36 ± 14.23, and 32.7 ± 12.1, and all of which improved (P < 0.05); (3) The scores of physical health were 68.24 ± 7.44, mental health were 69.75 ± 7.15, social function were 69.08 ± 7.43, material life were 37.46 ± 4.85 and the total score were 230.79 ± 9.56, all of which improved (P < 0.05). For patients with VD, CCRT can improve their cognitive function, social function, daily life ability and quality of life.

Application of Nursing Outcome-Oriented Integrated Zero-Defect Nursing Combined with Respiratory Function Training in Long-Term Bedridden Patients Undergoing Stroke.

Objective To explore the application effect of nursing outcome-oriented integrated zero-defect nursing combined with respiratory function training in long-term bedridden patients with stroke. Methods A total of 120 long-term bedridden patients with stroke were randomly divided into three groups: groups A, B, and C. Group A was given nursing outcome-oriented integrated zero-defect nursing combined with respiratory function training, group B was given nursing outcome-oriented integrated zero-defect nursing, and group C was given routine nursing. Rosenbek aspiration degree classification criteria were used to evaluate the incidence of aspiration; blood oxygen saturation, arterial oxygen partial pressure, and respiratory pressure were compared before and after the intervention. The swallowing function was evaluated by a water swallowing test (WST). The quality of life was assessed using the Generic Quality of Life Inventory-74 (GQOLI-74). Results After treatment, the Rosenbek aspiration degree of groups A and B were better than those of group C (P < 0.05); the improvement degree of respiratory function indexes in group A was better than those in B and C, and the blood oxygen saturation and arterial blood oxygen partial pressure in group B were better than those in C (P < 0.05). The incidence of complications in groups A and B was lower than that in C, and complications in group A were lower than that in B (P < 0.05). After treatment, the scores of psychological function, social function, and material life status of the three groups were increased, and each score of groups A and B was higher than that of C, and each score of group A was higher than that of B (P < 0.05). Conclusion Nursing outcome-oriented integrated zero-defect nursing combined with respiratory function training can effectively improve aspiration, respiratory function, swallowing function, complication rate, and quality of life in long-term bedridden patients with stroke.

Influence of Evidence-Based Nursing on Psychological Status, Neurological Function, and Life Quality of Patients with Acute Poststroke Depression.

Objective This research sets out to elucidate the influence of evidence-based nursing (EBN) on psychological status (PSY), neurological function, and quality of life (QoL) of patients with acute poststroke depression (PSD). Methods One hundred and fifty stroke patients who received treatment in the Characteristic Medical Center of PLA Rocket Force between December 2019 and December 2021 were enrolled, including 100 cases (Group A) treated with comprehensive EBN and 50 patients (Group B) with routine nursing. Anxiety and depression (Self-Rating Anxiety Scale [SAS] and Self-Rating Depression Scale [SDS] scores), neurological function (National Institutes of Health Stroke Scale [NIHSS] and Scandinavian Stroke Scale [SSS] scores), QoL (Generic Quality Of Life Inventory-74 [GQOLI-74] score), and complication rate of both groups were evaluated, as well as total effective rate and nursing satisfaction. Results Group A outperformed Group B with lower scores of NIHSS, SSS, SAS, and SDS and higher GOOLI-74 scores. Besides, lower complication rate and higher total effective rate and nursing satisfaction were determined in Group A. Conclusions EBN can better improve the PSY of patients with acute PSD, restore their neurological function, and effectively improve their QoL.

Influence of Self-Practice Oriented Teaching plus Psychological Intervention on Blood Glucose Level and Psychological State in Patients with Type 2 Diabetes Mellitus on Insulin Therapy.

Background The study aimed to examine the effect of self-practice oriented teaching plus psychological intervention on blood glucose level and psychological status of type 2 diabetic patients on first insulin therapy. Methods A total of 80 patients with type 2 diabetes admitted from April 2020 to November 2020 were assessed for eligibility and included. They were then assigned to a control group and an observation group via the random number table method, with 40 cases in each group. In addition to insulin injection treatment in both groups prior to intervention, the control group received health education and psychological intervention, whereas the observation group adopted a self-practice oriented teaching strategy plus psychological intervention. Insulin injections, nursing satisfaction, blood glucose level, and disease awareness were compared between the two groups. The Exercise of Self-Care Agency (ESCA) scale was used to assess the patients' self-care ability, the Generic Quality of Life Inventory-74 (GQOLI-74) scale was used to assess their quality of life, and the emotional state of patients was evaluated by the Hospital Anxiety and Depression (HAD) scale. Results Patients in the observation group outperformed the control group in terms of insulin injection after intervention (P < 0.05). Significantly higher nursing satisfaction and ESCA scores were observed after intervention (P < 0.05). Self-practice oriented teaching plus psychological intervention resulted in remarkably lower postintervention glycemic indexes (P < 0.001). Markedly higher disease knowledge scores and GQOLI-74 scores were witnessed in the observation group in contrast to those of the control group (P < 0.001). The observation group patients showed lower HAD scores than those of the control group (P < 0.001). Conclusion Self-practice oriented teaching plus psychological intervention could effectively alleviate the negative emotions of type 2 diabetic patients on first insulin therapy, stabilize glycemic indexes, and improve quality of life, demonstrating good potential for clinical promotion.

Systematic Nursing Interventions Combined with Continuity of Care in Patients with a Spinal Fracture Complicated with a Spinal Cord Injury and Its Effect on Recovery and Satisfaction.

Objective The aim of this study is to examine the application value of systematic nursing interventions combined with continuity of care in cases with a spinal fracture complicated with a spinal cord injury and its effect on recovery and satisfaction. Methods We identified ninety cases with a spinal fracture complicated with a spinal cord injury who were admitted to local hospital from May 2019 to May 2021 as research subjects and assigned them into an experimental group (systematic nursing combined with continuity of care, n = 45) and a control group (conventional nursing, n = 45) according to their admission order. The level of life of all groups between intervention was evaluated with reference to the Generic Quality of Life Inventory-74 (GQOLI-74) Rating Scale. The Hospital Anxiety and Depression (HAD) scale was used to assess the emotional status of patients before and after intervention. The complication rates, nursing outcomes, nursing satisfaction, and rehabilitation outcomes of all cases were calculated. Results The GQOLI-74 score of the experimental group was higher than that of another group (P < 0.05). Lower HAD scores of experimental group were observed than that of another group (P < 0.05). The experimental group obtained remarkably higher nursing effective rates and higher nursing satisfaction than another group (P < 0.05). Rehabilitation outcome of the experimental group outperformed that another group (P < 0.05). Conclusion The use of systematic nursing intervention combined with continuity of care for cases with spinal fracture complicated with a spinal cord injury can enhance the nursing effect, effectively relieve cases' psychological pressure, improve patients' level of life and nursing satisfaction, and contribute to the maintenance of a good nurse-patient relationship, which merits clinical promotion.

The Clinical Effects of Metronidazole Vaginal Effervescent Tablets Combined with Kushen Suppository in the Treatment of Trichomonas Vaginitis.

Objective The aim of this study was to explore the clinical effects of metronidazole vaginal effervescent tablets combined with Kushen suppository in the treatment of Trichomonas vaginitis. Methods Ninety patients with trichomoniasis admitted to our hospital from January 2019 to January 2020 were prospectively analyzed and randomly divided into a control group (n = 45) treated with metronidazole vaginal effervescent tablets and an experimental group (n = 45) treated with Kushen suppository on top of the control group using the random number table method. The clinical effects, inflammatory factors, and microcirculation indexes were compared. We assessed patient's vaginal health by Vaginal Health Score Scale (VHS) before and after treatment and estimated their quality of life according to Generic Quality of Life Inventory-74 (GQOLI-74). A follow-up visit was conducted to compare patient's recurrence 3 months after treatment. Results Distinctly higher total clinical effective of the experimental group compared with that of the control group was obtained (P < 0.05); the serum level of inflammatory factors of the experimental group was dramatically lower than that of the control group after treatment (P < 0.001); the experimental group experienced a favorable microcirculation index in comparison with the control group (P < 0.001); superior VHS (P < 0.001) and GQOLI-74 (P < 0.05) scores of the experimental group after treatment compared to those of the control group were observed; the recurrence rate of the experimental group 3 months after treatment was significantly decreased in comparison with that of the control group (P < 0.05). Conclusion Metronidazole vaginal effervescent tablets combined with Kushen suppository can effectively improve the clinical symptoms of patients with trichomonas vaginitis, abate patient's inflammatory reaction, and raise their quality of life, which is worthy of promotion.

Effect of montelukast/budesonide formoterol powder inhalation in chronic obstructive pulmonary disease

Purpose: To investigate the clinical efficacy of montelukast/budesonide formoterol powder inhalation in treating chronic obstructive pulmonary disease (COPD) and its impact on serum high-sensitivity Creactive protein (hs-CRP), cancer antigen 125 (CA-125), and interleukin (IL)-6 levels.Methods: In total, 86 COPD patients treated in the clinic of Department of Respiratory Medicine inYichun People’s Hospital between December 2019 and December 2020 were recruited and randomly assigned to group A and group B alternately at the point of admission. Group B received conventional treatment, while group A was treated with conventional treatment plus montelukast/ budesonide formoterol powder inhalation.Results: Patients receiving montelukast /budesonide formoterol powder inhalation showed lower scores for cough, sputum, and shortness of breath, compared conventional treatment (p &lt; 0.001). Patients in group A showed lower serum levels of hs-CRP, CA-125, and IL-6 after treatment than those in group B (p &lt; 0.05). Pulmonary function and arterial blood gas indices were significantly different between the two groups after treatment (p &lt; 0.05). Montelukast /budesonide formoterol powder inhalation resulted in higher Generic Quality Of Life Inventory-74 (GQOLI-74) scores and 6-min walking distance (6MWD) scores in patients than conventional treatment (p &lt; 0.001). Also, Group A had a lower incidence of adverse reactions than group B (p &lt; 0.05).Conclusion: Montelukast/budesonide formoterol powder inhalation has a better therapeutic effect versus conventional treatment, and improves patients' lung function and exercise tolerance. Further clinical trials are, however, required prior to general use in clinical practice.

The Tumor Plastic Surgery Technology versus Traditional Repair Technology on the Repair of Large-Area Skin Defects after Maxillofacial Tumor Resection: A Randomized Controlled Trial.

Objective To explore the effect of tumor plastic surgery on the repair of large-area skin defects after maxillofacial tumor resection. Methods 90 patients undergoing maxillofacial tumor resection in our hospital from March 2019 to March 2020 were selected and randomized 1 : 1 to receive either tumor plastic surgery (experimental group) or traditional repair (control group). The clinical efficacy and facial cosmetic improvement of the two groups were compared. The Patient and Observer Scar Assessment Scale (POSAS) was used to evaluate the surgical outcomes of the two groups, the Profile of Mood States (POMS) was used to evaluate the patients' psychological status, and the Generic Quality of Life Inventory-74 (GQOLI-74) was used to assess the quality of life of patients. Results Total clinical effective rate of the experimental group was significantly higher than that of the control group (p < 0.001). A higher excellent rate of facial cosmetic improvement was observed in the experimental group versus the control group (p < 0.001). Significantly lower POSAS scores of the experimental group than the control group were observed (p < 0.001). The POMS scores of the experimental group after treatment were lower than those of the control group (p < 0.001). Tumor plastic surgery resulted in a remarkably higher GQOLI-74 score in the patients versus traditional repair (p < 0.001). Conclusion Tumor plastic surgery is a promising alternative for patients undergoing maxillofacial tumor resection. It can effectively promote the recovery of facial morphology and physiological function of patients, with high clinical efficacy, so it merits promotion and application.

Dynamic interaction nursing intervention on functional rehabilitation and self-care ability of patients after aneurysm surgery.

BACKGROUNDNursing practices based on the dynamic interaction model have been shown to be superior to generic nursing practices. However, whether this model is effective in patients recovering from intracranial aneurysm surgery is not well studied.AIMTo investigate the effect of nursing based on a dynamic interaction model on functional rehabilitation of patients after aneurysm surgery. METHODSA total of 86 cases in our hospital with intracranial aneurysm from April 2019 to April 2021, were selected and divided into the study group and the control group, with 43 patients in each group. The control group received routine nursing, and the research group received nursing intervention based on a dynamic interaction model. The daily living ability (activities of daily living, ADL), cognitive function (Simple Intelligent Mental State Scale, MMSE), quality of life (Generic Quality of Life Inventory-74, GQOL-74), self-care ability (Exercise of Self-Care Agency scale), incidence of complications, and nursing satisfaction were recorded before and after intervention.RESULTSBefore intervention, ADL (52.09 ± 6.44), MMSE (18.03 ± 4.11), and GQOL-74 (53.68 ± 4.34) scores in the study group were not significantly different from those in the control group (ADL: 50.97 ± 7.32, MMSE: 17.59 ± 3.82, GQOL-74: 55.06 ± 3.98) (P > 0.05). After intervention, ADL (86.12 ± 5.07), MMSE (26.64 ± 2.66), and GQOL-74 (83.13 ± 5.67) scores in the study group were higher than those in the control group (ADL: 79.81 ± 6.35, MMSE: 24.51 ± 3.00, and GQOL-74: 77.96 ± 6.27) (P < 0.05). Before intervention, self-concept (17.46 ± 4.44), self-care skills (25.22 ± 4.20), self-care knowledge (22.35 ± 4.74), and self-care responsibility (15.06 ± 3.29) scores in the study group was similar to those in the control group (self-concept: 16.89 ± 5.53, self-care skills: 24.59 ± 4.46, self-care knowledge: 21.80 ± 3.61, and self-care responsibility: 14.83 ± 3.11) (P > 0.05). After the intervention, self-concept (26.01 ± 3.18), self-care skills (37.68 ± 6.05), self-care knowledge (45.56 ± 5.83), and self-care responsibility (22.01 ± 3.77) scores in the study group were higher than those in the control group (self-concept: 22.97 ± 3.46, self-care skills: 33.02 ± 5.65, self-care skills knowledge: 36.81 ± 5.54, and self-care responsibility: 17.97 ± 3.56 points) (P < 0.05). The incidence of complications in the study group (4.65%) was lower than that in the control group (18.60%) (P < 0.05). Nursing satisfaction in the study group (95.35%) was higher than that in the control group (81.40%) (P < 0.05).CONCLUSIONNursing intervention based on a dynamic interaction model can improve postoperative cognitive function, daily living ability, self-care ability, quality of life, and patient satisfaction, while reducing the risk of complications.