The escalating development of digital technologies over the last several decades has given rise to an accompanying surge in data analysis.The software based smart applications increase the importance of behaviour analysis. Software testing of expert systems such as electronic health records, health information system and software as a medical device (SaMD) refers to detect the difference between expected behaviour and actual outcome during healthcare expert systems development. Test cases are the core source of effective software testing. Test cases generation for expert systems are discover challenges of identifying the expected behaviour of the system, where the decision logic is obtained via a data –driven paradigm. In the traditional system software object oriented expected behaviour, provide the clear test cases does not change the flow such as in the healthcare system. Intelligent software test case generation approach required for smart health systems. In this research contributes key performance indicators from massive data sets, node –link diagrams from decision trees, test cases from adjacency matrix are elaborated. The experimental results of healthcare expert systems provide empirically evidence that topological data analysis are compact contribution for software requirement validation.
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