There remains a progressive projected deficit in the vascular surgery (VS) workforce for decades yet to come. Despite the rise of an expanding integrated VS residency pathway, the fellowship training model remains critical in supporting our future workforce. Therefore, it is imperative to understand the resident and program-specific factors that influence VS specialization among general surgery (GS) residents. Data from the US Resident OPerative Experience (ROPE) Consortium, comprising 20 Accreditation Council for Graduate Medical Education (ACGME)-accredited GS residency programs across the United States, were queried for resident demographics and residency program-related details. Logistic regression analysis was used to identify factors associated with VS specialization. From 2010 to 2020, a total of 1343 graduating GS residents were included in the study. Of these, 135 (10.1%) pursued VS fellowship training. Residents pursuing VS were more frequently male (80.7% vs 62.8%, p<0.0001) and younger (median 32 vs 33 yr, p=0.03) compared with other GS residents. Racial and ethnic group, underrepresented in medicine (URiM) status, and international medical graduate (IMG) status were similar between VS and non-VS groups. Residency program-level details were also similar between groups, including program type (university vs community-based), region, size, resident volume, dedicated research experience, and National Institutes of Health funding. Dedicated vascular rotations were common among all GS programs (95.4%), and total months spent on a VS rotation (median 4 vs 4.5 mo, p=0.11) did not differ among residents pursuing VS and all other residents. The presence of a collocated traditional (5+2) VS fellowship (91.1% vs 90.4%, p=0.79) or integrated (0+5) VS residency (56.3% vs 55.0%, p=0.77) were also similar between groups. On multivariate analysis, only male sex (odds ratio 2.34, 95% confidence interval, 1.50-3.81, p<0.001) was associated with pursuing VS fellowship. Factors that did not impact VS specialization included resident age, URiM status, IMG status, program volume, dedicated research experience, or total months spent on a VS rotation. In this multi-institutional study, we did not find any program-specific factors that influence VS specialization among GS residents. Notably, the presence of a collocated 0+5 residency or 5+2 fellowship program did not appear to deter GS residents from pursuing VS fellowship. These data suggest that individual factors, such as mentorship, may be more impactful in recruiting GS residents to the VS specialty.