This article addresses the problem of cooperation and coordination transportation for decoupling nonholonomic mobile manipulators (NMMs) in a workspace with obstacles. We propose a distributed model predictive control (MPC) approach for a team of NMMs to transport a target object while satisfying significant constraints and limitations, such as the feasible state and control input constraints, parameter synchronization constraints, and obstacles within the workspace. First, under the framework of the decoupling dynamics, an auxiliary dynamics model for task-space end-effectors and null-space mobile bases is obtained by the nonlinear feedback technique based on the Euler–Lagrange description of the NMMs. Using the modified virtual structure method, the cooperation and coordination transportation problem for NMMs is simplified as two independent synchronization tracking control problems for task-space end-effectors and null-space mobile bases. A distributed constrained optimization problem is established by taking the parameter synchronization and system constraints into the cost function. A general projection neural network (GPNN) approach is employed to solve the optimization problem and obtain the optimal control input. Moreover, a sufficient condition that guarantees the stability of the closed-loop system is further developed. Simulation results show that the proposed cooperation and coordination transportation strategy is feasible and effective.