British Journal of Pharmacology and ChemotherapyVolume 29, Issue 2 p. 238-247 Free Access THE KININ-FORMING AND KININASE ACTIVITIES OF RABBIT POLYMORPHONUCLEAR LEUCOCYTES* L. M. GREENBAUM, L. M. GREENBAUM Department of Pharmacology, College of Physicians and Surgeons, Columbia University, New York Career Scientist of the Health Research Council of the City of New York.Search for more papers by this authorK. S. KIM, K. S. KIM Department of Pharmacology, College of Physicians and Surgeons, Columbia University, New YorkSearch for more papers by this author L. M. GREENBAUM, L. M. GREENBAUM Department of Pharmacology, College of Physicians and Surgeons, Columbia University, New York Career Scientist of the Health Research Council of the City of New York.Search for more papers by this authorK. S. KIM, K. S. KIM Department of Pharmacology, College of Physicians and Surgeons, Columbia University, New YorkSearch for more papers by this author First published: February 1967 https://doi.org/10.1111/j.1476-5381.1967.tb01956.xCitations: 33 † Supported by a grant from the Life Insurance Medical Research Fund and the General Medical Research Fund of the National Institutes of Health. AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL References Cohn, Z. A. & Hirsch, J. G. (1960). The isolation and properties of the specific cytoplasmic granules of rabbit polymorphonuclear leucocytes. J. exp. med., 112, 983– 1004. Edery, H. (1964). Potentiation of the action of bradykinin on smooth muscle by chymotrypsin, chymotrypsinogen and trypsin. Br. J. Pharmac Chemother., 22, 371– 379. Erdös, E. G. & Sloane, E. M. (1962). An enzyme in human blood plasma that inactivates bradykinin and kallidins. Biochem. Pharmac., 11, 589– 592. Erdos, E. G., Sloane, E. M. & Wohler, I. M. (1964). Carboxypeptidase in blood and other fluids. 1. Properties, distribution, and partial purification of the enzyme. Biochem. Pharmac., 13, 893– 905. Greenbaum, L. M., Freer, R. & Kim, K. S. (1966). Kinin forming and inactivating enzymes in polymorphonuclear leucocytes. Fedn. Proc. Fedn. Am. Soc. exp. Biol., 25, 287. Greenbaum, L. M. & Hosoda, T. (1963). Studies on the isolation of bradykininogen. Biochem. Pharmac., 12, 325– 330. Greenbaum, L. M. & Yamafuji, K. (1966). The role of cathepsins in the inactivation of plasma kinins. In Proceedings of the 3rd International symposium on Hypotensive Peptides, ed. E. G. Erdös, N. Back and F. Sicuteri, held Florence, Italy, 1965. Springer Verlag, New York. Greenbaum, L. M. & Yamafuji, K. (1966a). The in vitro inactivation and formation of plasma kinins by spleen cathepsins. Br. J. Pharmac. Chemother., 27, 230– 238. Greenbaum, L. M., Yamafuji, K. & Hosoda, T. (1965). Peptic degradation of bovine bradykininogen. Biochem. Pharmac., 14, 411– 420. Janoff, A., Bean, M. A. & Schuller, E. (1965). Mediators of inflamation in leukocyte lysosomes. Life Sci., 4, 2361– 2373. Lewis, G. P. (1963). Pharmacological actions of bradykinin and its role in physiological and pathological reactions. Ann. N.Y. Acad. Sci., 104, 236– 249. Lewis, G. P. (1964). The role of peptides in the first stages of inflammation. In: International Symposium on Irjury, Inflammation and Immunity, ed. L. Thomas J. W. Uhr & L. H. Grant Williams and Willims, Baltimore. Pierce, J. V. & Webster, M. E. (1961). Human plasma kallidins; isolation and chemical studies. Biochem. biophys. Res. Commun., 5, 353– 357. Rogers, D. E. (1964). Intracellular inflammation: dynamics and metabolic changes in polymorphonuclear leukocytes participating in phagocytosis. In: International Symposium on Injury, Inflammation and Immunity, ed. L. Thomas, J. W. Uhr & L. H. Grant Williams and Wilkins, Baltimore. Schwab, J. (1962). Kininases in leucocytes and other tissues. Nature (Lond.), 195, 345– 347. Werle, E. (1955). The chemistry and pharmacology of kallikrein and kallidin. In: Polypeptides which Stimulate Plain Muscle, 20– 27, ed. J. H. Gaddum Livingstone, London. Citing Literature Volume29, Issue2February 1967Pages 238-247 ReferencesRelatedInformation