In 1999 Gender Reassignment Surgery (GRS) for patients with Gender Identity Disorder (GID) became available on the British National Health Service (NHS); however patients must first consult two psychiatrists and undergo comprehensive psychological assessment, demonstrating desire to live in the acquired gender for two years. Since 1999 the number of GRS performed annually tripled. GRS is only performed in highly specialised centres, and in recent years a surge in demand has heavily impacted waiting-lists. There are 4500 referrals to GID clinics in England yearly, rising by 30% yearly, by 2017 waiting-lists for GRS are predicted to exceed three years. The study aimed to evaluate the psychological effect on GID patients of prolonged waiting times for GRS. A literature search was undertaken on MEDLINE, PubMed, and Google Scholar for all scientific articles published in English. The literature search was extended by applying the “related article” and by manually searching the references sections of the generated articles.