A unifying scheme based on an ancestor model is proposed for generating a wide range of integrable discrete and continuum as well as inhomogeneous and hybrid models. They include in particular discrete versions of sine-Gordon, Landau–Lifshitz, nonlinear Schrödinger (NLS), derivative NLS equations, Liouville model, (non-)relativistic Toda chain, Ablowitz–Ladik model, etc. Our scheme introduces the possibility of building a novel class of integrable hybrid systems including multicomponent models like massive Thirring, discrete self-trapping, two-mode derivative NLS by combining different descendant models. We also construct inhomogeneous systems like Gaudin model including new ones like variable mass sine-Gordon, variable coefficient NLS, Ablowitz–Ladik, Toda chains, etc. keeping their flows isospectral, as opposed to the standard approach. All our models are generated from the same ancestor Lax operator (or its q→1 limit) and satisfy the classical Yang–Baxter equation sharing the same r-matrix. This reveals an inherent universality in these diverse systems, which become explicit at their action-angle level.