Anomaly Of Gastrointestinal Tract Research Articles

Congenital Anomalies in Yemeni Newborns: A Retrospective Study at a Tertiary Care Hospital in Sana’a City

Background: Congenital anomalies (CAs) are major causes of morbidity and mortality among newborns worldwide. Therefore, the present study aimed to determine the prevalence and types of CAs in Sana’a city, Yemen.
 Methods: This retrospective, cross-sectional study was conducted among newborns admitted to Al-Thawra Modern General Hospital in Sana’a from January to December 2017. Data were collected from 1100 medical records of newborns, besides data about their mothers, using a predesigned data collection sheet. Data were then analyzed, and the results were presented as frequencies and proportions.
 Results: Of 1100 newborns, 164 (14.9%; 95% confidence interval: 12.9–17.1) newborns had CAs. Of these, 74.4% had single-system CAs, and 25.6% had multiple-system CAs. Gastrointestinal tract anomalies (43.9%) were the most frequent CAs, followed by anomalies of the central nervous system (CNS) (18.9%), musculoskeletal system (17.1%), chromosomes (15.2%) and cardiovascular system (14%). However, orofacial anomalies of cleft lip and cleft palate (2.4%) were the least frequent CA, followed by urogenital anomalies (8.5%). Esophageal atresia (33.3%) and imperforated anus (25%) were the most frequent gastrointestinal CAs. On the other hand, meningocele (35.4%) was the most frequent CNS anomaly. Of musculoskeletal anomalies, limb defects were the most frequent (96.4%), while achondroplasia was observed among 3.6% of newborns with CAs. Congenital heart disease was the most frequent cardiovascular anomaly (95.7%), while dextrocardia was observed among 4.3% of newborns. Hypospadias (57.2%) was the most frequent urogenital anomaly, followed by ureteropelvic junction obstruction (21.5%). More than half of newborns with CAs died, while 35.4% of them were discharged from hospital without correction of CAs. On the other hand, CAs were corrected for 11.6% of newborns before discharge.
 Conclusion: The prevalence of CAs among Yemeni newborns is relatively high and can be observed in more than one in ten newborns. The majority of CAs usually affect a single system, most frequently affecting the gastrointestinal tract, followed by the CNS, musculoskeletal system, chromosomes and cardiovascular system. Half of newborns with CAs usually die in hospital before discharge. Therefore, it is necessary to educate parents and conduct regular antenatal screening by a pediatrician to detect these anomalies and manage them appropriately and in a timely manner.

Predictive Ability of Ultrasound on Neonatal Diagnoses and Consequences on Prenatal Care Utilization.

Fetal anomalies suspected on fetal ultrasound may cause significant stress for patients. Some findings resolve or have minimal clinical significance for the neonate. Our purpose is to evaluate fetal ultrasound accuracy and false-positive results and determine the clinical impact on maternal counseling. A retrospective review was performed on electronic medical records for women receiving prenatal care at Harbor-UCLA Medical Center who had abnormal findings on fetal ultrasounds between January 2015 and December 2018. Corresponding neonatal medical records were reviewed for the suspected condition(s). χ2 and Fisher exact tests were conducted to assess associations between fetal ultrasounds and neonatal outcomes. Two hundred eight mothers and 237 babies (including all 29 sets of twins) were included in the final analysis. Fetal ultrasounds were significantly associated with neonatal findings for the following conditions (sensitivity, specificity): anatomical disorder of extremities (0.72, 0.97), anatomical disorder of the face/skull/brain (0.67, 0.91), congenital anomaly of gastrointestinal tract (0.75, 0.98), congenital heart disease (0.75, 0.91), genetic disorder (0.72, 1.00), growth restriction (1.00, 0.85), kidney disorder (0.55, 0.98), and large for gestational age (0.80, 0.98). The highest false-positive rates occurred in congenital heart disease (65.4%), anatomical disorder of the face/skull/brain (64.3%), and growth restriction (54%). Fetal ultrasound highly correlates with neonatal findings for many congenital conditions. However, it can also be associated with a high false-positive rate for certain diagnoses; maternal counseling should include the limitations of ultrasound, including the potential for false-positive results.

A Case of Prune Belly Syndrome: Radiological Aspects of a Rare Disease

Prune Belly Syndrome (PBS) is a rare but morbid entity usually found in male neonates. It is classically defined by a triad of cardinal features that includes deficient abdominal wall musculature, urinary tract malformation and in males, cryptorchidism. Most of the patients have associated pulmonary, cardiac, skeletal and gastrointestinal tract anomalies. Children often require numerous surgical interventions including bilateral orchidopexy as well as individually tailored urinary tract and abdominal wall reconstruction. The prognosis of infants with PBS may be improved by quality antenatal follow-up, to enable the early diagnosis and preparation for prompt surgical intervention. We describe a case of PBS and emphasize the role of imaging, in the process of diagnosis and briefly review the subject.

Bleeding giant Meckel diverticulum, masquerading as abdominal tuberculosis

Meckel’s diverticulum is the most common congenital anomaly of gastrointestinal(GI) tract. It’s clinical presentation varies with age and overlaps with multiple GI pathologies. We are presenting a case of 18-year old boy presenting with overt lower GI bleeding, suspected to be intestinal tuberculosis based on imaging and Mantoux test. Initially responded to anti-tubercular treatment. However, his symptoms of GI bleed recurred, and repeat computed tomography(CT) scan showed suspicion of small bowel stricture with a dilated bowel loop. Exploration revealed a giant Meckel’s diverticulum which was resected and patient remained asymptomatic in the follow-up for 2 years. Bleeding giant Meckel’s diverticulum is sparingly reported in literature. However, even in tuberculosis endemic countries it showed be suspected as a possible cause of lower GI bleeding in young age group.

The morphological features of anencephaly in North Indian population

Background: Anencephaly occurs due to the complete absence of cranial vault and subsequent disruption of the cerebral cortex with a severely damaged brain. In anencephaly, the forebrain and brain stem are exposed. Forebrain either does not develop or is destroyed, leading to the absence of cerebrum and cerebellum. Methodology: Neural tube defects were taken in the study group. During the autopsy, clinical findings, external examination, internal examination, and photography were done along with the histopathology of the specimens to confirm the anomalies at microscopic level using hematoxylin and eosin staining. Results: In our study, we observed a simian crease in 4 out of 5 (80%) cases. Furthermore, there was presence of tooth which was not seen in previous studies. Central nervous system anomalies like spina bifida, gastro intestinal tract (GIT) anomalies like cleft palate, intestinal obstruction of megacolon, and malrotation of gut were some of the common anomalies which were observed in our study. Conclusion: It may be suggested that Anencephaly shows a female predisposition and the cases seems to be associated more in the primigravida females.The classical phenotypic presentation of anencephaly having absent cranial vault ,low set ears, protruding eyes were present in all subjects studied. In our study, we observed a simian crease in 4 out of 5 (80%) cases. Furthermore, there was presence of tooth which was not seen in previous studies. Central nervous system anomalies like spina bifida, GIT anomalies like cleft palate, intestinal obstruction of megacolon, and malrotation of gut were some of the common anomalies which were observed in our study.

Challenges in prenatal diagnosis of foetal anorectal malformation and hydrocolpos – Case report

and importance: Foetal hydrocolpos and anorectal malformation are difficult to diagnose prenatally due to abundance of differential diagnoses. This case report presents the challenges of diagnosing such disorders. A G3P2A0 woman came at 32 weeks of pregnancy with a referral for foetal ovarian cyst. Ultrasound revealed a singleton breech pregnancy, estimated foetal weight 3528g. A septate abdominal cyst measuring 11.31×7.17 cm and polyhydramnios were present. Elective caesarean section delivered a female baby weighing 2820g and measuring 43 cm. Neonatal examination revealed a right lateral suprapubic mass and a rectovestibular fistula. A sinoscopy revealed a suspected hydrocolpos. An abdominal hydrocolpos drainage was performed; a patent urachus and normal bilateral adnexa were present. Hydrocolpos is a rare congenital disorder due to distal obstruction of various etiologies. It may be mistaken with other pathologies, including fetal ovarian cysts. A genitourinary congenital abnormality may occur in conjunction with other abnormalities, including gastrointestinal tract anomalies. The presence of imperforate anus and/or fistula should alert the clinician of a possible association with VACTERL syndrome. Hydrocolpos is a rare congenital genitourinary disorder with various differential diagnoses. Simultaneous presence of other abnormalities is likely, with possible association to other syndromes.

MECKELS DIVERTICULUM WITH MESENTERY AS A RARE CAUSE OF CLOSED LOOP OBSTRUCTION-A CASE REPORT

Meckel's Diverticulum is most common congenital anomaly of gastrointestinal tract. It arises from Antimesenteric border of the small bowel [1]. In contradiction, a case encountered at our institution where a 32-y old female presented with complaints of pain abdomen since 3 days, vomiting's since 3 days, obstipation since 3 days and distention since 1 day. On examination abdomen is distended, diffuse tenderness present all over the abdomen with no bowel sounds and collapsed rectum with no fecal staining per rectally. Imaging studies on ultra-sonography shown dilated small bowel loops with max diameter of 3.1cm showing to and fro peristalsis. On CT abdomen multiple dilated small bowel loops with air uid levels with maximum diameter of 4.1cms with collapsed terminal ileum and large bowel. ?Closed Loop Obstruction. Emergency exploratory laparotomy was planned and shown Meckel's diverticulum with mesentery present on anti-mesenteric border with mesentery extending from mesenteric border to tip of Meckel's diverticulum with internal herniation of proximal ileum between the Meckel's and its mesentery causing closed loop obstruction noted at 60cms from IC junction for which herniated bowel loops was released with diverticulectomy followed by anastomoses of proximal and distal ileal loops. Resected Meckel's sent for histopathological examination and cut section showed mucosa, sub-mucosa, muscularis propria and serosa. Mucosa shows chronic nonspecic inammation, sections from the adjacent area's shows hyperplastic mucosa, hypertrophied muscularis layers and serosa with congested blood vessels with feature's consistent with Meckel's diverticulum. Patient was followed for 6 months, and the course was un-eventful.

Coexisting gastrointestinal and hepatobiliary tract anomalies in omphalocele and gastroschisis: A twenty-year experience in a single tertiary medical center.

Omphalocele and gastroschisis are the two most common congenital abdominal wall defects; however, no previous study has focused on gastrointestinal and hepatobiliary tract malformations in these two conditions. This study aimed to investigate the demographic characteristics, coexisting congenital gastrointestinal and hepatobiliary tract anomalies, hospital course, and outcomes of patients with gastroschisis and omphalocele. This is retrospective chart review of all patients admitted to one tertiary medical center in Taiwan between January 1, 2000 and June 30, 2020 with a diagnosis of gastroschisis or omphalocele. The medical records were reviewed to obtain demographic data regarding coexisting gastrointestinal and hepatobiliary tract anomalies and outcomes. Of the 51 patients included, 21 had gastroschisis and 30 had omphalocele. Gastroschisis was associated with a significantly younger maternal age and a higher incidence of small for gestational age. Of the 30 patients with omphalocele, twelve had associated gastrointestinal and hepatobiliary anomalies. Seven of the 21 patients with gastroschisis had gastrointestinal anomalies, and none had hepatobiliary anomalies. Among the omphalocele patients, three (10%) had documented malrotation, and one developed midgut volvulus. Among gastroschisis patients, four patients (19%) had malrotation, and two developed midgut volvulus. There were no statistically significant differences in postoperative complications or mortality rates between those with and without gastrointestinal/hepatobiliary tract anomalies. The diversity of coexisting gastrointestinal and hepatobiliary tract anomalies is higher in the omphalocele than in gastroschisis. In addition, we demonstrate that patients with gastroschisis or omphalocele have a higher rate of intestinal malrotation and midgut volvulus.

Major Congenital Malformations of Gastrointestinal Tract Among Neonates Presenting to Tertiary Care

Background: Major congenital malformations of gastrointestinal tract (CMGIT), are usually manifested in early neonatal period by signs of intestinal obstruction and may be life threatening. A broad spectrum of Gastrointestinal Tract (GIT) anomalies can be seen including both upper and lower GIT. As compared to other congenital anomalies, GIT anomalies are not well studied and till now very few studies have reported prevalence and pattern of GIT malformations. Objective: To determine different type of common gastrointestinal anomalies among neonates presenting at tertiary care hospital. Methods: This descriptive cross sectional study was done at National Institute of Child Health (NICH) Karachi over period of 6 months, from 1-8-17 to 31-1-18. All neonates presenting to emergency department and got hospitalized with CMGIT were enrolled. Results: There were 35 neonates enrolled with CMGIT. Out of these 16(45.7%) were male and 19(54.3%) were females. Mean age 9.4+3.82 (range 1-20) days. Mean weight was 2.5±0.98 (range 0.5-4.5) kg. Mean duration of symptoms was 5.8+1.72 (range 1-9) days. Among the CMGIT, 12 (34.3%) cases were of Anorectal malformation, persistent Vitelline duct was found in 6 (17.1%), Intestinal atresia in 4(11.4%), Intestinal stenosis in 5(14.3%), Hirshsprung disease in 4(11.4%) and Exomphalos in 4 (11.4%). Conclusion: Anorectal malformations were most common anomaly followed by persistent vitelline duct. Antenatal follow up and anomaly scan of all neonates should be done. Keywords: Gastrointestinal anomaly, Neonates, congenital anomaly.

Frequency and Pattern of GIT Anomalies in Neonates: A Retrospective Study at NICU Mayo Hospital Lahore

Aim: To acknowledge magnitude and spectrum of congenital anomalies of gastrointestinal tract in neonates and to establish possible factors resulting in these congenital anomalies. Material And Methods: The design of this study was Retrospective observational study. This study was conducted at NICU department of pediatric surgery King Edward medical university / Mayo hospital Lahore from June 2021 to May 2022. Neonates admitted in NICU department of pediatric surgery with gastrointestinal congenital anomaly were included in this study. Neonates having congenital anomaly other than GIT were excluded. Patient information regarding diagnosis and possible cause of congenital anomaly was noted on prescribed proforma. Results: During the study period total 256 neonates were admitted in neonatal ICU department of pediatric surgery Mayo hospital Lahore. Out of these 156(60.9%) neonates were having congenital anomalies of gastrointestinal tract while reaming 100(39.1%) neonates were having congenital anomalies of other structures. Most common congenital anomaly of GIT was anorectal malformations 35(22.4%) followed by Intestinal atresia’s in 30(19.2%). Conclusion: Congenital anomalies play an important role in neonatal mortality rate of any developing country like Pakistan. Chromosomal disorders, environmental and infectious factors are major contributing factors. Gastrointestinal tract anomalies are the most common anomalies of neonates with predominance of anorectal malformations. Antenatal care and timely interventions can reduce frequency of these anomalies. Keywords: Congenital anomalies, gastrointestinal tract, pattern.

Frequency of Common Congenital Anomalies among Neonates in Tertiary Care Hospital: A Cross-sectional Study

Aim: To determine the frequency of common congenital anomalies among neonates in tertiary care hospital
 Study Design: A cross-sectional study.
 Place and Duration: Children Hospital Larkana Pakistan from April to October 2018.
 Methodology: One hundred twenty-four newborns with congenital anomalies were included in this study after taking parental consent. All the newborns were assessed by prenatal, natal, and postnatal history, general physical examination, and relevant investigations like ultrasound abdomen, echocardiography, and CT Scan Brain were done; Questionnaire was filled out immediately within 24 hours after hospital admission.
 Results: The mean maternal age of the patients was 24.16±4.13 years. Central nervous system (CNS) anomalies were observed in 21% of cases. Neural tube defects like hydrocephalus 6.5%sacrococcygeal teratoma 2.4%, meningomyelocele 11.3%, and encephalocele 0.8%. Cardiovascular system (CVS) anomalies were found in 11.3% cases in which cyanotic 2.4%, (2 were Tetralogy of Fallot and 1 was Transposition of great arteries) Acyanotic 8.9% (10 Ventricular septal defects and 1 atrial septal defect). Gastrointestinal tract (GIT) Anomalies (39.5%) like, duodenal atresia (0.8%), anorectal malformations (25%), Pyloric Stenosis (0.8%), exomphalocele (5.6%), diaphragmatic hernia (2.4%), Hirschsprung disease (4.8%). Genitourinary system abnormalities (16.9%) like Hypospadias (14.5%), undescended testes (0.8%), cloacal exstrophy (0.8%) and hydrometrocolpos (0.8%). Musculoskeletal abnormalities (11.3%) like clubfoot (0.8%), developmental dysplasia of Hip (0.8%), polydactyly (1.6%) and cleft lip & palate (8.1%) of cases.
 Conclusion: Congenital abnormalities are prevalent in our setup, and the CNS is the most commonly involved system, followed by the gastrointestinal system, genitourinary system, cardiovascular system, and musculoskeletal system. The prevalence and pattern of congenital defects must be known in order for healthcare providers to create preventive interventions at various levels.

Preterm Infant of Diabetic Mother with a Retrorectal Mass: A Troubling Tail Tale.

Preterm Infant of Diabetic Mother with a Retrorectal Mass: A Troubling Tail Tale.

Congenital Anomalies in Neonates Admitted in Neonatal Intensive Care Units, Cairo University

Abstract Background: Congenital anomalies comprise a wide range of abnormalities of body structure or function that are present at birth and are of prenatal origin. Congenital anomalies defined as structural changes that have significant medical, social or cosmetic consequences for the affected individual, and typically require medical intervention. Three to seven percent is the estimated worldwide incidence of congenital anomalies, with 295000 newborns die within 28 days of birth every year worldwide due to congenital anomalies. Aim of Study: This study aims to detect the incidence of congenital anomalies in neonates admitted in Neonatal Inten-sive Care Units, Cairo University in the year 2014 and the associated risk factors present in their parents. Patients and Methods: We retrospectively reviewed the records of neonates having congenital anomalies admitted in Neonatal Intensive Care Units, Cairo University Children Hospital over one year from January 2014 to January 2015. Our collected data include full history with pedigree, full clinical examination and investigations. Results: 1105 neonatal 's records collected from Neonatal intensive care units, Cairo University for one year, four hundred sixty five (42%) of them having congenital anomalies, with high mortality (30.5%) from congenital anomalies, consanguineous marriage represent with 28.8%. Gastrointes-tinal tract anomalies are the most common congenital anom-alies (48.6%) followed by cardiovascular system (24.3%) respiratory system (4.3%) urinary and genetic causes (1.9%), mothers have chronic illness represent (10.3%) with eight% took drug during pregnancy. Conclusion: We found that there is high incidence of congenital anomalies in our Neonatal Intensive Care Units this is mostly related to that we are tertiary referral center and also most of these cases collected from surgical unit and need surgical interference and related to high incidence of consanguineous marriage. Congenital anomalies can contribute to long-term disabil-ity, which may have significant impacts on individuals, families, health-care systems and societies. The exact causes of congenital anomalies cannot be identified so close follow-up of pregnant women is highly indicated. Some congenital anomalies can be prevented. For example, vaccination, adequate intake of folic acid or iodine during pregnancy and adequate antenatal care are keys for prevention.

CASE REPORT : RARE CASE OF SMALL BOWEL OBSTRUCTION DUE TO MECKELS DIVERTICULUM

Meckels diverticulum is a rare congenital anomaly of gastrointestinal tract, seen in 2% of population. It was first described by Guilhemus Fabricus Hildonus in 1598. Meckels diverticulum is an anomaly derived from incomplete obliteration of omphalo-mesenteric duct. It is rarely seen in adults, with prevalence of male to female of 2:1. Complications associated with Meckels diverticulum are hemorrhage, inflammation and intestinal obstruction. We present to you a case of 17 year old male with unusual mechanism of small bowel obstruction due to Meckels diverticulum.

The Diagnostic Yield of Prenatal Genetic Technologies in Congenital Heart Disease: A Prospective Cohort Study

Introduction: The objective was to evaluate: (i) the proportion of prenatally diagnosed congenital heart disease (CHD) associated with an abnormal quantitative fluorescence-PCR (QF-PCR), chromosome microarray (CMA), and exome sequencing (ES) result; and (ii) the diagnostic yield of these technologies based on CHD category and presence of extra-cardiac anomalies (ECAs). Methods: This prospective cohort study was set across 12 UK foetal medicine centres. All cases underwent QF-PCR, CMA, and ES, and the diagnostic yield in n = 147 cases of prenatally diagnosed CHD was assessed. Results: In 34.7% (n = 51/147), a genetic diagnosis was obtained. Using a stepwise testing strategy, the diagnostic yield for QF-PCR, CMA, and ES was 15.6% (n = 23/147), 13.7% (n = 17/124), and 10.2% (n = 11/107), respectively. Abnormal QF-PCR/shunt (septal) defects 31.4% (n = 11/35), p = 0.046, and abnormal CMA/conotruncal anomalies 22.7% (n = 10/44), p = 0.04, had significant associations. Monogenic variants were commonest in complex CHD 36.4% (n = 4/11). Multisystem CHD had a greater diagnostic yield overall compared to isolated OR 2.41 (95% CI, 1.1–5.1), particularly in association with brain and gastrointestinal tract anomalies. The proportion of variants of uncertain significance was 4.7% (n = 5/107) with ES, with none in the CMA group. Conclusion: In the era of prenatal ES, there remains an important role for QF-PCR and CMA. Identification of monogenic pathologic variants further allows delineation of prognosis in CHD.

Gastrik Duplikasyon Kisti: Ender Bir Olgu Sunum

Duplication cysts are developmental anomalies of gastrointestinal tract that can occur at any level from the oral cavity to the rectum, and are extremely rare in the stomach. Most patients show symptom and findings in the first year of life. The most common symptom and findings are abdominal pain, nausea, vomiting, anemia, weight loss and palpable mass. In this study, a gastric duplication cyst was presented in an 11-month-old patient.

Evolution of Resting Energy Expenditure, Respiratory Quotient, and Adiposity in Infants Recovering from Corrective Surgery of Major Congenital Gastrointestinal Tract Anomalies: A Cohort Study.

This cohort study describes the evolution of resting energy expenditure (REE), respiratory quotient (RQ), and adiposity in infants recovering from corrective surgery of major congenital gastrointestinal tract anomalies. Energy and macronutrient intakes were assessed. The REE and RQ were assessed by indirect calorimetry, and fat mass index (FMI) was assessed by air displacement plethysmography. Longitudinal variations over time are described. Explanatory models for REE, RQ, and adiposity were obtained by multiple linear regression analysis. Twenty-nine infants were included, 15 born preterm and 14 at term, with median gestational age of 35.3 and 38.1 weeks and birth weight of 2304 g and 2935 g, respectively. In preterm infants, median REE varied between 55.7 and 67.4 Kcal/kg/d and median RQ increased from 0.70 to 0.86–0.92. In term infants, median REE varied between 57.3 and 67.9 Kcal/kg/d and median RQ increased from 0.63 to 0.84–0.88. Weight gain velocity was slower in term than preterm infants. FMI, assessed in a subset of 15 infants, varied between a median of 1.7 and 1.8 kg/m2 at term age. This low adiposity may be related to poor energy balance, low fat intakes, and low RQ¸ that were frequently recorded in several follow-up periods.

Lower Gastrointestinal Bleeding Caused by Meckel’s Diverticulum

Meckel’s diverticulum is a congenital anomaly of gastrointestinal tract with an incidence of 2% in the general population. It occurs due to the persistence of omphalomesenteric duct during embryonic period of life. It may be asymptomatic or can manifest as intestinal obstruction or massive lower GI bleeding. It usually presents before the age of 2 years and may contain ectopic tissue. Here, we are reporting a case of 7-year-old child with Meckel’s diverticulum presenting as painless bleeding per rectum and anemia.

Enteric duplication cyst in a neonate: A case report

Duplication cysts of intestine are rare congenital malformations formed due to some developmental anomaly of gastrointestinal tract during embryonic period. They can occur in any portion of the gastrointestinal tract but are more commonly seen in small intestine. They have a variable clinical presentation depending on the size, site and type, or they may remain asymptomatic. In most of the cases they are detected during infancy or early childhood and uncommon in adults. Antenatal ultrasound can detect the condition in fetus and helps in follow- ups subsequently. Treatment of asymptomatic case is controversial, however early intervention prevents complications. Herein, we share our experience of managing a neonate with enteric duplication cyst, detected antenatally.

Antenatal predictors of intestinal pathologies in fetal bowel dilatation.

Fetal bowel dilatation (FBD) in the late trimester of pregnancy can be related with varies of prognosis. Our aims were to obtain antenatal factors that might have relevance for the distinct prognosis with FBD. Seven features of 68 pregnancies presented with FBD were assessed. The best cut-off value to predict intestinal outcomes was selected using receiver-operating characteristics curves, and the effective variables were included into a logistic regression model. The best cut-off valves to predict intestinal pathologies were 14.5 mm of fetus dilated loop and 37.7 weeks of gestational age at delivery, respectively. The congenital gastrointestinal tract anomalies included 24 cases (92.3%) of intestine atresia, 1 case (3.85%) of small intestine volvulus and 1 case (3.85%) of midgut malrotation. Fetal dilated loops and gestational age at delivery are both an independent risk factor for predicting intestinal pathologies of newborns, which should arouse high attention.