Gastrectomy For Ulcer Disease Research Articles

Increased risk of laryngeal and pharyngeal cancer after gastrectomy for ulcer disease in a population-based cohort study

Background:Gastrectomy has been indicated as a risk factor for laryngeal cancer, and possibly also for pharyngeal cancer, but few studies are available. The postulated mechanism is increased bile reflux following gastrectomy.Methods:This was a population-based cohort study of patients who underwent gastrectomy for peptic ulcer disease between 1964 and 2008 in Sweden. Follow-up data for cancer was obtained from the Swedish Cancer Register. Relative risk was calculated as standardised incidence ratios (SIRs) with 95% confidence intervals (CIs).Results:The gastrectomy cohort comprises 19 767 patients, contributing 348 231 person-years at risk. The observed number of patients with laryngeal (n=56) and pharyngeal cancer (n=28) was two-fold higher than the expected (SIR: 2.0, 95% CI: 1.5–2.6 and SIR: 2.4, 95% CI: 1.6–3.5, respectively). After exclusion of 5536 cohort members with tobacco- or alcohol-related disease, the point SIRs remained increased (SIR: 1.6, 95% CI: 1.1–2.2 and SIR: 1.7, 95% CI: 0.9–2.8, respectively). The SIRs of laryngeal and pharyngeal cancer increased with time after gastrectomy (P for trend <0.0001), and were particularly increased ⩾30 years after gastrectomy (SIR: 4.8, 95% CI: 2.1–9.5 and SIR: 10.2, 95% CI: 3.7–22.3, respectively).Conclusion:Gastrectomy for peptic ulcer disease might entail a long-term increased risk of laryngeal and pharyngeal cancer.

Totally Laparoscopic Billroth I Gastrectomy

Gastrectomy for ulcer disease, although less common than in the past, remains effective and powerful in a surgeon’s armamentarium. Laparoscopic Billroth II gastrectomy has been previously described1–3 and laparoscopic-assisted Billroth I has five entries in the medical literature.4–10 We describe a technique for gastrectomy vagotomy and Billroth I reconstruction accomplished totally intraabdominally. Before performing this totally laparoscopic Billroth I on a human, the technique was trialed in 1995 in the Animate Laboratory at the Ethicon Endosurgery Institute in Cincinnati, Ohio.

Gastrectomy for Ulcer Disease

Gastrectomy for Ulcer Disease

Review of fifteen years' experience with gastrectomy in a community hospital.

THIS report is based on a study of the total experience with gastrectomy at the Salem Hospital during a fifteen-year period, 1939–1953. Three hundred and eight gastrectomies were performed by 26 surgeons. Indications for gastrectomy are listed in Table 1. The contrast between increasing frequency of gastrectomy for ulcer disease and the fairly constant number for gastric carcinoma is striking (Fig. 1). A study of a fifteen-year period was made to minimize the error potential of an inadequate number of cases. It is appreciated that certain statistics such as the mortality rate must necessarily suffer by comparison with rates cited in . . .