This study aims to conduct a sensitivity analysis of closure models and modeling parameters for the Dense Discrete Phase Modeling (DDPM) approach in order to investigate the hydrodynamics of a 3D lab-scale Tapered Fluidized Bed (TFB). The closure models and model parameters under investigation include the gas-solid drag force, viscous models, particle-particle interaction models, restitution coefficient, specularity coefficient, and rebound coefficient. The primary objective of this sensitivity analysis is to optimize the numerical model's performance. The numerical results, in terms of axial and lateral Solid Volume Fraction (SVF) profiles obtained from the sensitivity analysis, indicate that the drag force and restitution coefficient significantly influence the hydrodynamics of the TFB. Properly selecting these parameters could result in the improved performance of the numerical model. However, the sensitivity of turbulence models, particle-particle interaction models, specularity coefficient, and rebound coefficient has a lesser impact on the hydrodynamics results. This work concludes with the recommendation of a set of closure models and modeling parameters that offer the most accurate prediction of the hydrodynamics of the TFB.