This paper proposes a set of novel fuzzy controllers with adjustable control forces for the robust synchronization of different chaotic systems that include uncertain terms or unexpected disturbances. The proposed fuzzy rule-based control system is developed through Lyapunov stability theory and the fuzzy logic concept to form a multi-input multi-output (MIMO) system. This system provides flexible control inputs based on the error dynamics of the system, and the inputs satisfy the synchronization condition of being asymptotically stable. In this case, the error derivatives always have signs opposite those of the error states, which yields negative definite first-order Lyapunov function derivatives. Furthermore, the proposed system appropriately adjusts the control inputs through the constructed fuzzy if-then rules. This method is robust to both unmodeled terms and unexpected interference signals during the synchronization process. The simulation results demonstrate the feasibility and effectiveness of the proposed fuzzy rule-based control system.