The land use changes driven by human activities press a incredible menace to zonal ecological security. As the most active urban cluster, the uncontrolled expansion of cities in the bay area exerts enormous pressure on the ecosystem. Therefore, from the perspective of ecological conservation, exploring future land use optimization patterns and spatial structure is extremely essential for the long-term thriving of the bay area. On this basis, this research integrated the System Dynamics model (SD) as the quantity forecast model and the PLUS model as the spatial emulation model and established the Land Use/Cover Change (LUCC) Simulation Framework by setting the constraints of Ecological Security Multi-Scenario Patterns (ESMP). By setting four scenarios in future, that is, Business As Usual (BAU), Priority of Ecological Protection (PEP), Balanced Development Scenario (BD), and Priority of Urban development (PUD), this research predicts LUCC in the Zhejiang Greater Bay Area (ZGBA) in 2035 and explored land use optimization patterns. The results indicate that by 2035, under the scenarios of BAU, BD, and PUD, the construction land will observably grow by 38.86%, 19.63%, and 83.90%, respectively, distributed mainly around the Hangzhou Bay Area, Taizhou Bay Area, and Wenzhou Bay Area, primarily achieved by sacrificing ecologically sensitive lands such as forests to achieve regional high economic growth. Under PEP, the growth of construction land retards, and forest experiences net growth (11.27%), with better landscape connectivity and more cohesive patches compared to other scenarios. Combining regional planning and analysis at the city scale, Hangzhou Bay area (Hangzhou, Huzhou, Jiaxing, Shaoxing, Ningbo) can adopt the BD development scenario, while Zhoushan, Taizhou, Wenzhou and Fuyang County of Hangzhou can adopt the PEP development scenario. This research furnishes a novel mechanism for optimizing land use pattern in ecological security perspective and offers scientific guidance for land resource management and spatial planning in ZGBA.