Funding Source Research Articles

Financial Sustainability of Nongovernmental Organizations in Nepal: A Qualitative Study

This paper explores the financial sustainability of Nepalese NGOs, drawing insights from the resource dependency theory. The primary data were collected from the key informant interviews (N=15) with executives of development NGOs. The data were analyzed thematically based on Braun and Clarke’s (2006) framework using NVivo software. The findings showed that internal funding sources could not support NGOs financially. They were found to have suffered from resource constraints due to a decline in external funding opportunities. NGOs also appeared weak in adopting strategies necessary to maintain financial sustainability. The findings indicated the possibility of further resource constraints if the government and NGOs do not consider diversifying funding sources. Future studies should explore the internal financial management strategies of NGOs for maintaining their financial sustainability by employing case studies.

International research collaboration in personalized medicine between Europe and Latin America and the Caribbean

Abstract An analysis of research collaboration in personalized medicine between European and Latin American and Caribbean countries has been conducted in order to identify significant aspects allowing such collaboration. It aims to comprehend strategic issues for establishing research collaborations in personalized medicine between the two regions, as well as the structural factors that facilitate the collaboration. An exhaustive literature review of the subject was the basis for the development of a framework covering several factors that are significant at different stages of the collaboration process. The framework assisted in developing a questionnaire and defining relevant questions for a final survey, which was sent to more than 1,800 corresponding authors of publications resulting from collaborations between European and Latin American and Caribbean researchers. The results point out interesting issues like the profile of the collaboration partners, types of research collaboration, factors and motivations favouring the participation in collaborative research, ways to contact partners, funding sources and tools, main outputs or principal barriers to collaboration. Due to the lack of available information on research collaborations in the field of personalized medicine, this type of analysis is valuable to support science and research policy-making and to evaluate the various actions, initiatives and projects carried out in this scenario. Although our methodology and analysis focused on the field of personalized medicine, the results obtained could be helpful to better understand the reality of international scientific collaborations and support the design of collaborative funding programmes in other fields.

How feasible is it to mobilize $31 billion a year for pandemic preparedness and response? An economic growth modelling analysis

BackgroundCovid-19 has reinforced health and economic cases for investing in pandemic preparedness and response (PPR). The World Bank and World Health Organization (WHO) propose that low- and middle-income governments and donor countries should invest $31.1 billion each year for PPR. We analyse, based on the projected economic growth of countries between 2022 and 2027, how likely it is that low- and middle-income country governments and donors can mobilize the estimated funding.MethodsWe modelled trends in economic growth to project domestic health spending by low- and middle-income governments and official development assistance (ODA) by donors for years 2022 to 2027. We modelled two scenarios for countries and donors – a constant and an optimistic scenario. Under the constant scenario we assume that countries and donors continue to dedicate the same proportion of their health spending and ODA as a share of gross domestic product (GDP) and gross national income (GNI), respectively, as they did during baseline (the latest year for which data are available). In the optimistic scenario, we assume a yearly increase of 2.5% in health spending as a share of GDP for countries and ODA as a share of GNI for donors.FindingsOur analysis shows that low-income countries would need to invest on average 37%, lower-middle income countries 9%, and upper-middle income countries 1%, of their total health spending on PPR each year under the constant scenario to meet the World Bank WHO targets. Donors would need to allocate on average 8% of their total ODA across all sectors to PPR each year to meet their target.ConclusionsThe World Bank WHO targets for PPR will not be met unless low- and middle-income governments and donors spend a much higher share of their funding on PPR. Even under optimistic growth scenarios, low-income and lower-middle income countries will require increased support from global health donors. The donor target cannot be met using the yearly increase in ODA under any scenario. If the country and donor targets are not met, the highest-impact health security measures need to be prioritized for funding. Alternative sources of PPR financing could include global taxation (e.g., on financial transactions, carbon, or airline flights), cancelling debt, and addressing illicit financial flows. There is also a need for continued work on estimating current PPR costs and funding requirements in order to arrive at more enduring and reliable estimates.

Management of Islamic Philanthropy-Based Education Financing in Increasing Access to Free Education for Orphans Children

The article describes the management of Islamic philanthropy-based education financing in increasing access to free education for orphans and poor children at the Raudhatul Ulum Islamic boarding school, Sumberanyar Village, Lumajang Regency, East Java. This research uses qualitative research obtained by researchers based on data in the field. The research period starts from December 2023 to February 2024. The data source in this research is primary data obtained through interviews and direct observation with informants. The data analysis steps used in this research are the Interactive Analysis Model from Miles and Huberman: data reduction, data display, and conclusion drawing. Based on the research results after being dialogued with the results of the conceptual study, it can be described as Islamic philanthropy-based education financing management in Islamic boarding schools. Raudhatul Ulum Lumajang Regency includes three activities: planning sources of philanthropy-based education financing (waqf and infaq), allocating and distributing philanthropic fund financing, and monitoring and accountability (auditing) of philanthropic funds.

Risks of managing financial resources of the agricultural sector of Ukraine in the zone of military conflict: Challenges, threats, ways of counteraction

This study was aimed at identifying the risks that affect financial management in the agro-industrial sector of Ukraine during military operations in order to develop effective countermeasures. The research methodology included an analysis of the main risks, such as exchange rate fluctuations, inflation, disruption of supply chains and political instability, as well as an assessment of strategies to minimise these risks. The main stages of risk management are identified as identification, assessment, and monitoring of risks, as well as development of appropriate strategies, such as investment diversification, insurance, and hedging. The study results showed that the key factors for ensuring stability are the introduction of technological innovations, government support, creation of reserve funds and diversification of funding sources. In particular, the development of modern agricultural technologies, subsidies, soft loans and investments in infrastructure significantly increase the resilience of the agricultural sector to crisis conditions. It is also important to plan cash flows to maintain liquidity and meet financial obligations in a timely manner. The experience of several countries, such as Israel and Georgia, which have faced similar challenges, was reviewed and analysed to see how they managed the financial resources of their agricultural sectors. The experience of these countries has shown that successful management of the financial resources of the agricultural sector in the context of military conflict requires a comprehensive approach that includes technological innovation, government support, financial planning and human capital development to ensure sustainable development of the agricultural sector in times of war. This approach allows not only preserving but also developing the agricultural sector, ensuring food security and economic stability of Ukraine

Investigating environmental prioritization: role of financial resources and female entrepreneurship in the Mediterranean region

PurposeIn this study, we aim to define a new ecological financial pecking order. We examine how SMEs' adherence to the environment in the Mediterranean region is impacted by their financial resources and how women Entrepreneurship could play a moderating role in this relationship.Design/methodology/approachOur data are pooled cross-sectional firm level data across 14 Mediterranean countries, with a total of 5,949 observations over the period from 2018 to 2020. We look into the moderating influence of SMEs’ female ownership on the financial sources-environmental engagement link using GLS estimations. To reach our aim we focus on seven funding sources and develop a green engagement construct using JCA. Besides, we distinguish between the least and most environmentally engaged companies in the EU and its neighborhood and compare the different interactions and possible moderations.FindingsResults show that government subsidies foster environmental engagement, followed by supplier credits with a less significant positive impact. The bank credits have the least significant beneficial influence, while non-bank financial institutions have a non-significant effect. We underline that environmental engagements are hindered by the other funds, issued bonds and internal funds.Research limitations/implicationsSMEs in the Mediterranean region, particularly the less environmentally conscious, require strong legal frameworks to enforce environmental responsibility and raise awareness. Integrating less environmentally committed EU SMEs into state subsidy strategies is a chance to improve environmental responsibility in the region.Originality/valueTo our knowledge, there are no prior studies that present a detailed financial structure and environmental management investigation for SMEs within the Mediterranean region while considering the moderating effect of women's entrepreneurship.

A comparison of new transport projects in Sydney, Australia: Decomposition of the impact on residential property prices

Public transport projects are expensive, long-lived and their funding is often a challenge. As a result, relevant authorities around the world are concerned in understanding the economic impacts induced by these new public transport projects and, in particular, whether any increases in land value which may follow an investment (referred to as land value uplift) can be ‘captured’ as a potential source of funding. Land value uplift can occur at different stages of a project and might not be only due to the improved accessibility of the project. This study focusses on understanding the complexity of land value uplift on residential properties resulting from three public transport projects in Sydney, Australia (two light rail projects and one heavy rail), as a way of providing insights to create evidence-based value capture policies. Multilevel models are presented comparing the affected or ‘catchment’ areas of the projects with what is referred to as a ‘control area’ where the investment has not had an impact. The total residential land value uplift is analysed prior and post implementation – and decomposed into what can be attributed to improved accessibility, property characteristics, neighbourhood characteristics, time series, and unobserved uplift. The results show that the anticipated value uplift before the projects’ implementation is significantly higher for the heavy rail project (between 12 and 15 per cent after its construction process started for properties located within 800 m from the station) than for the light rail project (5.7 per cent only for properties located within 400 m from the station), but it is close to zero for the project that represents the anticipated uplift for a light rail extension project after its announcement. However, there is a significant value uplift for the light rail extension project after its implementation (around 6 per cent) which is mainly due to the accessibility improvements. The distance to stations also showed to be significant in the light rail and heavy rail projects, with properties closer to the stations having a higher anticipated value uplift.

A roadmap for affordable genetic medicines.

Twenty genetic therapies have been approved by the US Food and Drug Administration to date, a number that now includes the first CRISPR genome-editing therapy for sickle cell disease-CASGEVY (exagamglogene autotemcel, Vertex Pharmaceuticals). This extraordinary milestone is widely celebrated owing to the promise for future genome-editing treatments of previously intractable genetic disorders and cancers. At the same time, such genetic therapies are the most expensive drugs on the market, with list prices exceeding US$4 million per patient. Although all approved cell and gene therapies trace their origins to academic or government research institutions, reliance on for-profit pharmaceutical companies for subsequent development and commercialization results in prices that prioritize recouping investments, paying for candidate product failures and meeting investor and shareholder expectations. To increase affordability and access, sustainable discovery-to-market alternatives are needed that address system-wide deficiencies. Here we present recommendations of a multidisciplinary task force assembled to chart such a path. We describe a pricing structure that, once implemented, could reduce per-patient cost tenfold and propose a business model that distributes responsibilities while leveraging diverse funding sources. We also outline how academic licensing provisions, manufacturing innovation and supportive regulations can reduce cost and enable broader patient treatment.

A New Model of Rating to Evaluate Start-ups in Emerging Indian Market

Conceptualization of an idea to a well framed model is emerging with need of generating wealth at national base. Entrepreneurship is the crucial base of an economy measuring the wealth base thereby contributing to national income. The need for evaluation of these start- ups with some criteria is a pressing priority. The rating criterion has risen these days as the expressional value for an individual assessment for a company or a firm. There is a need to widen the range for rating to full fledge rating model considering financials and non-financial aspects by opening its arms towards the most important segment of economy i.e. start-ups. In consideration of this, the need to launch a well specified rating agency for start-up is need of the hour. Since there is no particular study defining its focus towards such need on national and international level, we want to explore this area of research so as to contribute to existing literature (which is very limited). Considering India, although there is much effort by government to boost start-ups initiatives like Atma Nirbhar Bharat, Start-up India, Make in India and relaxations in budgets etc. but there is no criterion to evaluate these start-ups in order to gain visibility. In this research paper we made an effort to frame a rating model considering the important factors affecting the start-up which can satisfy the need for the model. The model is framed by us considering all financial factors like sources of funds, working capital, financial performance, idle funds etc. and non-financial factors like founder details, descriptive, market variable and future aspects etc. which are essential for a start-up to evaluate and henceforth benefits in longer run-in terms of getting easy funding, financial support and more visibility. An extant literature review is done in order to cover all parameters focusing the evaluation of start-ups with a longer perspective by adding to existing literature and helping policy makers, entrepreneurs, venture capitalists who can use the model to assess the start-ups and henceforth can benefit the economy.

Housebuilding Finance in the United States: From Budgeting to Funding

This article precisely identifies housebuilding finance in the United States as a complex procedure of primary concern to those who wish to become homeowners or builders, susceptible to the state of the economy and shifts in policies. Therefore, the purpose of this research will be to provide extensive coverage of the processes involved in budgeting right through to obtaining and directing funds. This study adopts a qualitative research method to ascertain budgeting techniques, sources of finance, means of obtaining loans, financial controls during construction through literature, industry, and documents. Discussions also focus on the governmental initiatives and economic environment stressing the need for money comprehension. Issues such as budgeting down to the last detail, variety of financial sources and methods of financial management are highlighted as important aspects. Some recommendation areas are improvement of budgeting, increasing the financing options’ awareness, and the optimization of the existing times of lending to boost housebuilding finance in the USA.

Analysis of Local Government Financial Statements as A Basis for Making National Economic Recovery Loan (PEN) Policies in the Jakarta Provincial Government

This research was conducted to analyze local government financial statements as a basis for making decisions or policies on the use of Regional PEN Loans in the DKI Jakarta Provincial Government. Due to a decrease in revenue as a result of the co-19 pandemic, the DKI Jakarta Provincial Government is looking for other sources of funding to finance development to meet public services. The data used include budget and realization of regional income and expenditure, as well as the value of Construction in Progress which is supported by qualitative information in CaLK. The research method uses descriptive qualitative by collecting data in the form of images, numbers, tables, sentences, in the form of secondary data. The results of the study concluded that the information presented in the financial statements has an important role in assisting the policy making of the DKI Jakarta Provincial Government in applying for Regional PEN Loans and meeting the criteria as a loan recipient.

Literature Review: Penggunaan Dana BOS untuk Pengadaan Sarana dan Prasarana Sekolah

Technological developments influence the development of schools in Indonesia regarding the facilities and learning media used, especially in the procurement of school facilities and infrastructure which must be met and improved. Procurement of school facilities and infrastructure still requires clear and sufficient funding sources. One of the funds that can be used as a source is BOS funds which are used to fund all school operations and non-operations, one of which is for facilities and infrastructure. The use of these funds needs to be planned so that they are sufficient according to the funds and expenses. Facilities and infrastructure that have been met can be put to good use to support the smooth running of learning and attention must be paid to their maintenance.

The acquisition of foreign science and technology literature resources in specialized libraries amidst the challenges posed by science and technology blockade

Confronted with significant challenges in procuring foreign scientific and technological literature resources due to a global science and technology blockade, professional libraries are facing severe limitations imposed by the United States on China. These export control measures have severely hampered domestic scientific research institutions and universities from accessing foreign scientific and technological documents, thereby impeding China's progress in the field of scientific and technological innovation. To effectively address this predicament and enhance the ability to secure resources of foreign language scientific and technological literature, professional libraries should focus on the following five aspects: Firstly, diversify funding sources while expanding channels for procuring foreign periodicals; Secondly, increase procurement of English-language scientific and technological literature from non-American countries while organizing and categorizing these materials; Thirdly, strengthen access to non-English language scientific journals; Fourthly, promote collaborative construction and sharing of scientific and technological documents; Fifthly, develop localized versions of foreign digital resources. Ultimately, it is emphasized that bolstering one's own capabilities is key to overcoming barriers in accessing scientific and technological literature. Therefore, China should prioritize national-level development of digital academic platforms.

Quantitative Changes in the Publishing of Lithuanian Scientific Journals in 2015–2022: Public and Private Sectors’ Adaptation to the Changing Conditions

The article analyses the quantitative changes in the Lithuanian scientific journal publishing in 2015-2022. The study reveals the problems of public bibliographic accounting and terminology in order to comprehensively analyse the public and private sector published print and electronic scientific journals. The gaps and uncertainties identified allow for the improvement of official publication records in the future, avoiding ambiguities in the assessment of the publication volumes of scientific journals. Science policy makers and implementers should take the initiative to standardise the definition of scientific journals, as this is the only way to achieve a clearer approach to this form of science communication. Although the annual volume of scientific journal publications has shrunk by 18.1% (from 265 (2015) to 217 (2022) publications), the decline itself has not been sharp. The decline has been stabilised by business involvement, changes in the evaluation of colleges, and the transformation of professional journals, book series and conference proceedings into scientific journals. Flexibility has been provided by electronic publishing instruments, which have reduced the dependence on external financial sources. The public publishing sector has tended to reduce the number of scientific journals in all scientific fields. This was mainly due to the reorganisation of the higher education network, the qualitative requirements for scientific articles and the reorganisation of scientific collectives. The publishing business has seen the greatest potential in the fields of technology and the medical and health sciences, and as a result, the number of journals published in these fields has not declined and continues to grow. Despite the private sector's growth trends, 50% of journals have 30 or more years of publication. This forms the core of Lithuanian scientific journals, which public sector publishers are striving to preserve and integrate into the international scientific environment.

A Review of the Sustainable Siting of Offshore Wind Farms

The continued technical and economic development of offshore wind farms needs to match their sustainable siting transparently and fairly. Aiming to assess existing methodologies widely used in the field of OWFs spatial planning, as well as to identify the proposed enhancements for the improvement of such methods, this study examines 80 peer-reviewed papers over the past eight years. The analysis encompasses articles from 34 scientific journals, with a notable concentration in the journals Renewable Energy, Renewable and Sustainable Energy Reviews, and Energies, and it sheds light on geographical distribution, journal classification, funding sources, and the various methodological approaches. Most of the studies were conducted in Turkey, China, and Greece; half of the surveyed papers utilize multi-criteria decision-making approaches, predominantly addressing bottom-fixed technologies for offshore wind farms, which currently dominate the field. The 80 papers are categorized into five methodological domains: Marine Spatial Planning, Feasibility Analysis, Probabilistic Methods, Meteorological Data, and Multi-Criteria Decision Making. One hundred and seventy criteria were identified and condensed into a final set of 41 critical criteria. This article provided an overview of the site selection process and the most crucial findings and recommendations.

Blood methylation pattern reflects epigenetic remodelling in adipose tissue after bariatric surgery

Studies on DNA methylation following bariatric surgery have primarily focused on blood cells, while it is unclear to which extend it may reflect DNA methylation profiles in specific metabolically relevant organs such as adipose tissue. Here, we investigated whether adipose tissue depots specific methylation changes after bariatric surgery are mirrored in blood. Using Illumina 850K EPIC technology, we analysed genome-wide DNA methylation in paired blood, subcutaneous and omental visceral AT (SAT/OVAT) samples from nine individuals (N=6 female) with severe obesity pre- and post-surgery. The numbers and effect sizes of differentially methylated regions (DMRs) post-bariatric surgery were more pronounced in AT (SAT: 12,865 DMRs from-11.5 to 10.8%; OVAT: 14,632 DMRs from-13.7 to 12.8%) than in blood (9267 DMRs from-8.8 to 7.7%). Cross-tissue DMRs implicated immune-related genes. Among them, 49regions could be validated with similar methylation changes in blood from independent individuals. Fourteen DMRs correlated with differentially expressed genes in AT post bariatric surgery, including downregulation of PIK3AP1 in both SAT and OVAT. DNA methylation age acceleration was significantly higher in AT compared to blood, but remained unaffected after surgery. Concurrent methylation pattern changes in blood and AT, particularly in immune-related genes, suggest blood DNA methylation mirrors AT's inflammatory state post-bariatric surgery. The funding sources are listed in the Acknowledgments section.

Coffee Processing Business Feasibility In BUMDes Eka Giri Karya Utama Wanagiri Village, Buleleng Regency Bali Province

The potential for good coffee plantation yields needs to be developed and utilized to improve the village economy, which is the basis for establishing BUMDes Eka Giri Karya Utama. The development of this business unit is aimed at supporting an integrated coffee processing industry and being able to produce more efficiently and be able to produce products according to dynamic market demands. The research objectives were to describe governance, to analyze financial feasibility, and to analyze the level of sensitivity of the coffee processing unit in BUMDes Eka Giri Karya Utama. This research was made using descriptive analysis and business feasibility analysis with the investment criteria used being NPV (Net Present Value (NPV), IRR (Internal Rate of Return), Net Benefit-Cost Ratio (Net B/C), Payback Period, and sensitivity analysis. The type of data used is primary data collected by in-depth interviews, field observations, and literature study. There are two variables in this study, namely the benefits and costs variables. The results of the study show that the Village Owned Enterprises in their establishment are managed with the spirit of wanting to improve the village economy, making the village an independent village with all the potential that exists in the village. BUMDes management is carried out in a professional, transparent, participatory, and sustainable manner. sources of funds for this business unit come from the Ministry of Villages, Development of Disadvantaged Regions and Transmigration, and the local village government. Based on the results of the financial analysis, the NPV value was IDR 679,311,964.218, IRR was 31,60%, Net B/C was 2,85 and PP was 4 years 7 months 2 days. Furthermore, the results of the sensitivity analysis with an increase in operational costs by 25.18% obtained an NPV of IDR 434,079,320.45, an IRR of 23.17%, and a net B/C of 2.12. Then for the assumption of a 14.28% decrease in revenue, an NPV of IDR 388,934,679.50, an IRR of 22.02%, and a Net B/C of 2.02 are obtained. This coffee processing business unit is feasible. After all, it can provide benefits for the manager because it meets the investment criteria. Based on the sensitivity analysis, the assumption of a decrease in revenue is more sensitive than an increase in operational costs. In the future, for business development, managers need to innovate so that products become more attractive and have competitiveness as well as invest in human resources and marketing.

Coffee Processing Business Feasibility In BUMDes Eka Giri Karya Utama Wanagiri Village, Buleleng Regency Bali Province

The potential for good coffee plantation yields needs to be developed and utilized to improve the village economy, which is the basis for establishing BUMDes Eka Giri Karya Utama. The development of this business unit is aimed at supporting an integrated coffee processing industry and being able to produce more efficiently and be able to produce products according to dynamic market demands. The research objectives were to describe governance, to analyze financial feasibility, and to analyze the level of sensitivity of the coffee processing unit in BUMDes Eka Giri Karya Utama. This research was made using descriptive analysis and business feasibility analysis with the investment criteria used being NPV (Net Present Value (NPV), IRR (Internal Rate of Return), Net Benefit-Cost Ratio (Net B/C), Payback Period, and sensitivity analysis. The type of data used is primary data collected by in-depth interviews, field observations, and literature study. There are two variables in this study, namely the benefits and costs variables. The results of the study show that the Village Owned Enterprises in their establishment are managed with the spirit of wanting to improve the village economy, making the village an independent village with all the potential that exists in the village. BUMDes management is carried out in a professional, transparent, participatory, and sustainable manner. sources of funds for this business unit come from the Ministry of Villages, Development of Disadvantaged Regions and Transmigration, and the local village government. Based on the results of the financial analysis, the NPV value was IDR 679,311,964.218, IRR was 31,60%, Net B/C was 2,85 and PP was 4 years 7 months 2 days. Furthermore, the results of the sensitivity analysis with an increase in operational costs by 25.18% obtained an NPV of IDR 434,079,320.45, an IRR of 23.17%, and a net B/C of 2.12. Then for the assumption of a 14.28% decrease in revenue, an NPV of IDR 388,934,679.50, an IRR of 22.02%, and a Net B/C of 2.02 are obtained. This coffee processing business unit is feasible. After all, it can provide benefits for the manager because it meets the investment criteria. Based on the sensitivity analysis, the assumption of a decrease in revenue is more sensitive than an increase in operational costs. In the future, for business development, managers need to innovate so that products become more attractive and have competitiveness as well as invest in human resources and marketing.

Leishmaniases in Ethiopia: a scoping review protocol to determine the scope of research and remaining gaps

IntroductionThe leishmaniases are among the group of neglected tropical diseases that cause significant morbidity and mortality each year. Currently, the East Africa region has the highest visceral leishmaniasis burden in...

The Effect of Profitability, Liquidity and Company Size on Capital Structure in Companies Listed on the Indonesian Stock Exchange

This study investigates the effect of profitability, liquidity, and firm size on the capital structure of firms listed on the Indonesia Stock Exchange (IDX). Using data from manufacturing firms, the study found that profitability and liquidity have a negative and significant influence on capital structure decisions, with more profitable firms tending to rely on less debt and more internal sources of funds. However, firm size does not consistently have a significant negative impact on capital structure, suggesting that external factors such as capital market conditions and economic policies have a more dominant role in determining a firm's capital structure. These results provide important insights for financial practitioners in designing appropriate funding strategies to maximise firm value and effectively manage financial risk in the Indonesian capital market.