Functional State Of Cardiovascular System Research Articles

Effectiveness of different treatment regimens of enhanced external counterpulsation in patients with stable coronary artery disease complicated by heart failure

Aim. To study the effect of various therapy regimens with enhanced external counterpulsation (EECP) on exercise tolerance, quality of life, indices of structural and functional state of cardiovascular system in patients with stable coronary artery disease (CAD) complicated by chronic heart failure (CHF).Material and methods. The study included patients with stable CAD complicated by CHF with reduced and intermediate left ventricular ejection fraction (LVEF) from the randomized EXCEL trial (NCT05913778; n=120) and additionally patients with similar inclusion and exclusion criteria (n=90) who were randomized into groups with different EECP treatment regimens for 12 months: Group 1 (n=40): course of 35 hour-long procedures; Group 2 (n=40): course of 35 hourlong procedures every 6 months; Group 3 (n=30): course of 20 hour-long procedures then constantly 1 hour per week; Group 4 (n=30): constantly 2 hours per week; Group 5 (n=30): course of 20 hour-long procedures then constantly 2 hours per week; Group 0 (placebo ; n=40): course of 35 hour-long procedures with compression pressure 80 mm Hg. All patients at baseline and after 12 months were assessed for clinical status, quality of life (MLHFQ, SF-36), NT-proBNP levels, LVEF, as well as exercise tolerance (6-minute walk test; 6MWT) initially, after 3, 6, 9 and 12 months. Correlation analysis and risk assessment of adverse events (combined endpoint — combination of cases of adverse cardiovascular events, deaths, hospitalizations for CHF, new-onset of atrial fibrillation, diabetes, decreased renal function) was performed.Results. Treatment effectiveness had positive correlation with EECP duration (r(S)=0,670; p<0,001) and treatment regimen (r(S)=0,620; p<0,001). The maximum effect (changes in NT-proBNP levels, LVEF, clinical status, quality of life) was noted in the combined and constant regimen groups (5, 4, 2). The increase of 6WMTdistance was 6,6% in group 0, 24,9% in group 1, 44,5% in group 2, 31,8% in group 3, 49,1% in group 4, 58,6% in group 5. The proportion of patients with an increase in 6WMT-distance >20% after 12 months was 7,7%, 72,5%, 97,5%, 76,7%, 90%, 100%, respectively. Cumulative event-free survival was highest in groups 5, 4, and 2 (0,97, 0,93, and 0,86, respectively), and the risk of developing combined endpoint in these groups was minimal (0,035, 0,075, and 0,150, respectively).Conclusion. The effect of EECP treatment in patients with coronary artery disease complicated by CHF depended on the EECP hours and regimen. Alternative EECP regimens (with more treatments spread evenly over the year) in addition to optimal medical therapy may improve the management of these patients.

Impact of neurobiofeedback by beta rhythm of the brain on the functional state of cardiovascular system of athletes with different motor activity

To examine the impact of one procedure of neurobiofeedback by beta rhythm of the brain on the cardiovascular system functional state in the athletes with different character of motor activity. The study included 1020 male athletes aged 18-21 years. Depending on the motor activity, patients were divided into 5 groups: 1st group - cyclic sports athletes (38%); 2nd group - speed-power sports athletes (25%); 3rd group - combat sport athletes (3%); 4th group - team sports athletes (17%) and 5th group - athletes of complex coordination sports (17%). The procedure of neurobiofeedback by beta rhythm of the brain was done in the conditions of active waking at open eyes. Registration of bioelectric activity of the brain and training on beta rhythm were done in the Fz-Cz lead by the international system «10-20» with the arrangement of indifferent electrode on the earlobe of the subjects (PAC «BOSLAB», Institute of Molecular Biology and Biophysics, Novosibirsk, Russia). Heterochronic pattern of changes in the indicators of systemic pressure, cardiac and vascular activity of the athletes' body during a single procedure of neurobiofeedback by beta rhythm of the brain in the preparation period of the training process, depending on the character of athletic activities, was found. In response to the impact, the following indicators have changed significantly: heart rate and index of functional changes in combat sport athletes (3rd group); stroke and cardiac output in all groups. Cardiovascular regulation index and specific peripheral vascular resistance significantly increased in the groups 2-5. Cardiac index significantly decreased in the groups 1, 2, 4 and 5. Qualitative changes in types of blood circulation occurred in all groups: in groups 1, 3 and 5 - from hyperkinetic to eukinetic, in group 2 - from hyperkinetic to hypokinetic, in group 4 - from eukinetic to hypokinetic, contributing to the economization of cardiovascular activity function. The use of neurobiofeedback by the beta rhythm of the brain in the practice of sports medicine requires additional detailed research of the features and development of individual methods depending on the type of athletic activity, features of cardiac activity regulation, etc.

Components of Oranta-AO software expert system for innovative application of blood pressure monitors.

The authors developed and substantiated the original methods of arterial oscillography, which were implemented in the developed Oranta-AO information system. The methods of application to the arterial oscillogram registered at measurement of arterial pressure gives the possibility to carry out the supplementary systematic assessment of health, functional state of cardiovascular system, its reserve possibilities etc. The authors also developed an Expert System (based on machine-learning methods) for the differential diagnosis of risks of heart, lung, mental illness and prognosis of some blood parameters. Oranta-AO software system was created based on research results due to methods and algorithms that were innovate. For the mathematical modeling of arterial oscillograms used cyclic random processes. Methods of arterial oscillograms processing based on its model in the form of a cyclic random process was developed. The method of evaluation of the rhythm function of arterial oscillograms and statistical methods for estimating the probabilistic characteristics of arterial oscillograms were developed. To solve the clustering problem, the Python k-means and k-means++ algorithm were used. Oranta-AO information system consists of three interrelated parts: mobile application, computing kernel and web system. Computing kernel and web system are deployed on AWS servers and have been tested already. The developed environment aims to be integrated into every new model of electronic meters in the world. Certification (EN 62304:2014, ISO 13485: 2018) in Ukraine is completed, PCT priority is completed. The next step will be to establish cooperation with manufacturers of electronic pressure monitors, patenting and certification in world.

Methods of studying the cardiovascular system in students of a sports university in the process of recreational rest

Background and Study Aim. The aim of the study is to develop a methodology for examining the cardiovascular system in students with different levels of physical activity.
 Materials and Methods. Students of the Academy of Physical Culture (Kharkiv, Ukraine) took part in the study: 3-4 year full-time and part-time students. A scheme for examining the cardiovascular system in this category of students has been drawn up. A survey was conducted during practical exercises on physical recreation during the years 2006 – 2011. The research methods were taken as the basis: circulatory organs; patients with diseases of the cardiovascular system; circulatory systems.
 Results. The definitions of recreation are considered. Its types and functions are shown. Directions for assessing the level of the functional state of the cardiovascular system in students with a high level of physical activity are given. A plan-scheme for studying this system has been drawn up. The peculiarity of the system is to take into account the specifics of the future profession. Assessment of the functional state of the student's cardiovascular system is carried out in a complex manner.
 Conclusions. It is necessary to take into account the anamnesis of the entire life of the student. It is necessary to apply sports, clinical, instrumental, laboratory, biochemical research methods. The results of functional trials and tests should be taken into account. Functional tests and tests should reflect the response of the cardiovascular system to the physical load and determine the overall physical performance.

THE IMPACT OF QUERCETIN ON THE FUNCTIONAL STATE OF CARDIOVASCULAR SYSTEM AND HEMOSTASE IN RATS WITH TYPE 2 DIABETES MELLITUS

Introduction. Type 2 diabetes mellitus (T2DM) increases the risk for atherosclerotic cardiovascular disease and other cardiovascular complications such as cardiac arrhythmias, heart failure, and thrombotic events. Quercetin (Q) possesses a wide range of multiple activities: anti-diabetic, anti-proliferative, anti-atherosclerotic, antioxidant, anti-inflammatory, anti-thrombotic, anti-apoptotic effects and is regarded as a candidate for the role of cardiovascular complications protecting agent.
 The aim of this study was to assess the effects of Q on the functional state of cardiovascular system and haemostasis in diabetic rats.
 Materials and Methods. T2DM was induced in Wistar rats by a high-caloric diet during 14 weeks combined with intraperitoneal injections of 25 mg/kg streptozotocin twice per week. All diabetic animals were divided into three groups: treated with solvent and with Q (in dose 10 and 50 mg/kg/day per os) for 8 weeks after diabetes induction. Fibrinogen concentration and induced euglobulin fibrinolysis time were measured in plasma using reagent kits. Electrocardiograms were recorded in leads II.
 Results. It was established that Q in dose 50 mg/kg b.w. prevents in the formation of sinus tachycardia in experimental animals. In addition, Q in both doses inhibits the development of myocardial diastolic dysfunction, which was confirmed by prolongation of T-P interval and a decrease of duration of the T wave in comparison with diabetic rats. Q in both doses restorated the processes of coagulations and fibrinolysis, as indicated by a decrease of fibrinogen levels and the time of thrombolysis compared to diabetic rats.
 Conclusions. Q, independently of dose, inhibits the development of myocardial diastolic dysfunction and reduces prothrombotic potential in rats with type 2 diabetes, which may ameliorate diabetic cardiovascular risk. This data justify the perspective of Q for the prevention and management of cardiovascular complications in patients with type 2 diabetes.

Value of psychological adaptation of labor-intensive underground workers in formation of arterial hypertension regarding age aspect

Objective. To study the prerequisites for the development of hypertension based on the manifestation of psychovegetative dysfunction and some changes in the biochemical and functional parameters of CVS in the age aspect. Psychological adaptation of a group of underground miners in conditions of intensive labor was analyzed on the basis of indicators of psycho-vegetative status taking into account the influence of professional and psychosocial factors. In connection with the established diagnosis i.e. arterial hypertension (AH) syndrome, especially in middle-aged persons, it is of interest to study the indicators of psycho-vegetative status in the age aspect and to compare them with some changes in biochemical and functional state of cardiovascular system (CVS) in this contingent of patients.
 Materials and methods. The results of the study of psycho-vegetative status of 60 underground miners with AH syndrome (age 46.8 2.0 years, experience 22.0 2.4 years) using the method of psychophysiological testing as well as analysis of some clinical, functional and laboratory parameters are presented.
 Results. The adaptive psycho-vegetative phenotypes in a group of underground workers with AH syndrome in the age aspect were identified.
 Conclusions. With an increase in the length of service among labor-intensive workers, the characteristics of psycho-vegetative status change qualitatively in the form of elevated anxiety and neuro-psychical stress with a decrease in the function of attention combined with a negative relationship of these parameters with increasing age, that is accompanied by dysfunction of CVS; studying of this aspect allows identifying the prerequisites for the development of hypertension so as to form a risk group in time.

Calculation of kinds of reaction and level of stamina of UIAS students during realization of Letunov’s test physical load

The study is devoted to relevant problems of maintaining the healthy lifestyle of students of young age of Ukrainian Institute of Arts and Sciences. Calculating the kinds of reaction and level of stamina of students towards physical load according to Letunov’s test to discover the functional state of cardiovascular system.
 Moving activity is a necessary part of healthy lifestyle and is determined and stipulated by totality of physical activity of a person. Both excessive and lacking physical load can be negatively marked on health state of students under the conditions of term control. Rational usage of the means of physical education has its positive influence and irrational usage can cause pathological changes in the system of blood circulation. Results of medical examination of first year students claims that the quantity of students with deflections of health state increases every year. Correct organization of the process of physical education can become driving force of all the studying process by forming and strengthening the physical education of a personality. It happens by means of stimulating the development of the most significant biological and social needs of a person such as movement, development, self- affirmation, self-education. Nowadays during practice coordination of the studying process for teachers of physical education in school and also teachers of physical education in higher educational institutions unconventional cases happen in terms of admittance of a pupil for the physical education lesson or a student for a physical education lesson, taking into account a few accidents that happened at physical education lessons at schools, which are connected to the low level of health state of majority of students. Certainly, nowadays unfavorable ecological factors, high level of stressful situations, low level of water quality, low level of food quality, poor life standards influence negatively the city residents. [1]
 The implementation of modern technologies considerably fosters the decrease of physical activity, which stimulates notable rejuvenation of many diseases, that were typical for older population 10 years ago. [2,7,8]

Investigation of the functional state changes of cardio-vascular system in patients, suffering peritonitis

Objective. To study a functional state of cardio-vascular system in patients, suffering peritonitis.
 Materials and methods. Analysis of dynamics in the electrocardiogram changes in 166 patients, including 84 women and 82 men, was conducted for studying of functional state of cardio-vascular system in extended peritonitis.
 Results. Changes on electrocardiograms were non monotonous and depended on the peritonitis stage. In 28.3% patients diffuse changes in myocardium were observed, while in 43.9% - moderate. In 42.6% patients the disorders in metabolic processes in myocardium were revealed. Changes in conductivity and excitability were noted merely in half of the patients. Hypoxia was observed in 17.7% patients in reactive stage of peritonitis, in 32.0% - in a toxic, in 75.8% - in terminal. Tachycardia in a reactive stage of peritonitis was noted in 77.4% patients, in toxic one - in 89.3%, and in terminal - in 86.2% patients. In terminal stage of peritonitis in 13.8% patients bradycardia was noted. The blood supply disorders of various compartments of myocardium was revealed in 34.4% patients.
 Conclusion. Functional changes of cardio-vascular system in patients depends on stage of peritonitis. In all the patients, suffering peritonitis, medicinal correction of the cardio-vascular system work must be conducted, while its intensity depends on stage of peritonitis.

EFFECTIVENESS INDICATORS OF USING ETHNIC GAMES FOR THE IMPROVEMENT OF PHYSICAL STATUS AND ENDURANCE LEVEL OF PEOPLE IN MID-MOUNTAIN REGIONS (AGE PERIOD: 50-55 YEARS)

The article presents the effectiveness indicators of a brand new methodology developed by Kyrgyzstan. It focuses on application of outdoor ethnic games for the improvement of health status and endurance level of adults aged 50-55 in mid-mountain regions. The obtained results are applicable for the refinement of training process and the improvement of physical qualities of elderly people in special climate conditions. We analyzed the indicators of physical fitness, physical status, adaptive potential and endurance of adults aged 50-55. The outcomes demonstrated effectiveness of using outdoor ethnic games for the improvement of health status and the deceleration of age-related changes in the studied group. The reason is that all ethnic games have an active impact on all muscle groups, develop motor qualities and raise endurance. The purpose is to develop the methodology of application of outdoor ethnic games for the improvement of physical status and workability of persons of pre-retirement age in mid-mountain regions in Kyrgyzstan and to determine its effectiveness. Research methods: anthropometry, physiometry (body length, body weight, heart rate, blood pressure); functional tests: Davydenko 6-scale momentum test (Cooper test); methods of mathematical statistics. Results: In our research, we first identified the indicators of adaptive potential, the nature of adaptation, characteristics of functional state, physical status, and stamina level according to Davydenko 6-scale momentum test. We assessed the functional state of cardiovascular system according to the endurance coefficient. We used 12-minute Cooper test and monitoring of maximum oxygen consumption to identify the physical fitness degree of individuals of pre-retirement age who practice outdoor ethnic games in mid-mountain regions in Kyrgyzstan. Conclusion. We carried out the comparative analysis of current functional adaptation status of men playing ethnic games. The first observation revealed the decrease in body functional abilities. The second observation revealed the tension of adaptation mechanisms in men and women. Both men and women had either medium or high physical status. The studied group practicing modern physical culture demonstrated the same results and the same physical status. Results of Davydenko test show the increasing fitness level in both groups. Functional indicators of studied groups demonstrate the intensification of cardiac activity. It provides sufficient functional capabilities at the cost of functional reserves. Level of physical capacity degree in studied groups: satisfactory, good and high. The index of maximal oxygen consumption demonstrate good health of people in both groups.

Вплив загальної екстремальної аерокріотерапії на функціональний стан серцево-судинної системи

Вплив загальної екстремальної аерокріотерапії на функціональний стан серцево-судинної системи

Comparative evaluation of the functional state of cardiovascular system in adolescents living in conditions of various ambient air pollution

Comparative evaluation of the functional state of cardiovascular system in adolescents living in conditions of various ambient air pollution

ВПЛИВ СЕНСОРНИХ ПОДРАЗНИКІВ НА ФУНКЦІОНАЛЬНИЙ СТАН ОРГАНІЗМУ

Introduction. The studies of recent years have been actively demonstrating the possibility of using additional sensory afferentation in ensuring the optimal functioning of the cardiovascular system and the body as a whole. The organization of sensory visual effects can significantly change the functional state of the human cardiovascular system, mainly under the effect of compensatory shifts of its wave manifestations, which may become an important direction of the prophylactic medicine in the context of an increase in the number of cardiovascular diseases. Purpose. To characterize the current state of scientific ideas about the influence of sensory afferents on the functional state of the cardiovascular system and the organism as a whole. Methods. The analysis of special scientific literature,that considered the physiological mechanisms of sensory afferentation on the functional state of the cardiovascular system and the body as a whole. Results . Sensory effects promote the optimization of cardiac rhythm regulation, enhance coordination of cardiovascular and respiratory systems, improve emotional state and psychophysiological functions. Originality . The literature review of modern scientific publications due to the influence of sensory afferentation on the functional state of the cardiovascular system and the organism in general is presented in this article. Conclusions . The tension of the regulatory mechanisms of the organism, which is reflected in the changes in the tone of the autonomic nervous system, in particular, the results of central hemodynamics and their wave structure, can serve as a prognostic criterion for the development of pathology in the future. Physiological effects and mechanisms of the influence of various sensory stimulation on the functional state of the human organism have been insufficiently studied, and there is no scientific foundation for choosing qualitative and quantitative characteristics of sensory influences, its’ duration and purpose of the use, and also taking into account the peculiarities of human biological features .

Combination approach with ambulatory Blood Pressure and Electrocardiography Monitoring in Patients with Hypertension and Myocardial Infarction – A Prospective Study.

Introduction: With the increasing number of deaths due to cardiovascular events, there is an urgent need for optimising the risk factors associated with it. The safety and cost effective non-invasive method to assess the blood pressure and modulate the treatment plan accordingly is to utilise the ambulatory blood pressure monitoring and Holter Electrocardiography in daily use in patients with hypertension. Aim: To examine the functional state of cardiovascular system and possible predictive value of the daily application of the combined method of arterial blood pressure monitoring and ECG monitoring in hypertensive patients at different levels of the disease progression. Methods and materials: We examined 37 patients with AH without any clinical significant pathology were included in the first group and 32 hypertensive patients with a history of myocardial infarction (MI) in the second group. The average age of participants in this study was 59,02±2,18 years. All patients underwent a comprehensive examination of the functional state of the cardiovascular system using the combined ECG and arterial BP monitoring validated device «CardiosensBP» XAI-MEDICA (Ukraine). The statistical data was processed using «STATISTICA® for Windows 6.0» (StatSoft Inc., #AXXR712D833214FAN5). Results: The hypertensive state is characterized by an excess of the target values ??of systemic blood pressure: the daily mean values ??of systolic blood pressure (SBP) and diastolic blood pressure (DBP) were higher at 6,93% (P<0,05) and 5,68% (P<0,01) respectively in both groups. Indicators of pressure increase and morning surge(MS) are significant in patients of the second clinical group exclusively SBP, namely: the index of time (IT) - by 24,68% (P<0,01), the index of measurements (IM) - by 16,84% (P<0,05), MS - by 31,98% (P<0,01). Conclusions: The practice of application of daily arterial blood pressure and ECG monitoring has an important prognostic value in cardiovascular system functional status estimation and also enables the physician in optimising the treatment plan accordingly.

Hemodynamic Allostasis of Pregnant Women against the Background of Preeclampsia.

We analyzed diurnal hemodynamic parameters (HR, systolic BP, and diastolic BP) recorded from two groups of edematous and preeclamptic pregnant women. The unidirectional character of changes in the control over the functional state of cardiovascular system was revealed except for the indices, which mark a pathological process: elevated diurnal BP in preeclampsia and diminished percentage of oscillation power in edematous patients. Uniformity of the regulatory changes in patients with and without arterial hypertension can be viewed as manifestation of allostasis developed by the cardiovascular system during pregnancy. In preeclampsia, the greater allostatic load was reflected by the changes in diurnal, daytime, and nighttime BP and in the circadian index calculated for HR, systolic BP, and diastolic BP. In edematous patients, elevation of allostatic load was indicated by the percentage of ultradian rhythms.

Визначення ознак інвалідності в клініці сімейного лікаря: увага на функціональний стан серцево-судинної системи

Визначення ознак інвалідності в клініці сімейного лікаря: увага на функціональний стан серцево-судинної системи

Diferenciniu mokymo metodu grindžiamų aerobinio krūvio pratybų poveikis širdies ir kraujagyslių sistemos funkcinei būklei

Seeking for optimal and potentially more effective modes of exercising for health purposes remains an urgent problem today. It is well known that exercising must be individualized, that it is not recommended for exceptionally high intensity of workouts requiring high efforts, especially when a person chooses to exercise again after a longer dropout. The purpose of this study was to compare the changes in features of the cardiovascular system functional state in recovery phase after health-enhancing exercising, when this exercising are performed in easy aerobic mode and when such aerobic exercising are complemented by so-called “Differential Learning” (DL) methodology based tasks. Eight male volunteers were examined twice, i.e. in randomly completed sequence, performed two 20-minutes duration exercising sessions with a three-day break between them. It was the relatively ease workload (25W) on bicycle ergometer. One of the tasks was to assess the impact of exercising in aerobic mode, and the next on the exercising with the DL tasks while the participants during exercising was asked to perform simple tasks that required some coordinating efforts, and each subsequent task was a new variation of the task given before. The evaluations of the functional condition of the cardiovascular system were performed before the exercising, after 5 minutes and 30 minutes after the exercise session. The 12-lead standard ECG was registered continuously and the second-order matrix analysis (algebraic data cointegration approach) was used for assessment the dynamics of concatenation between RR interval and QRS complex duration and between the JT interval. These indices were chosen as reflecting different levels of myocardial regulation and features of metabolism. Results obtained during the study revealed that there was no significant differences (p > 0.05) while comparing the values of durations of RR intervals, JT intervals and the duration of QRS complex. Both aerobic exercising and exercising while the additional tasks based on DL methodology was added caused the same changes of registered electrocardiogram indices. Both, aerobic exercise exercising and the exercising with the DL tasks caused significant increase of concatenation between ECG indices (p > 0.05). Even after 30 minutes of exercising the increased concatenation remained significantly changed in comparison to the initial values recorded before exercising (p < 0.05). The assessment of concatenation between two electrocardiographic indices provides qualitatively new information about features of participant’s functional state. It is purposeful to apply the algebraic data cointegration approach for evaluation complexity features of sportsman body functioning during exercising, it allows to reveal the new features of functional state. It is concluded that aerobic exercising complemented with tasks based on DL methodology has made the stronger effect on the functional state of cardiovascular system. The increased concatenation between ECG indices remained substantially stronger in the recovery phase after exercising. Keywords: functional state, electrocardiography, differential learning. DOI: http://dx.doi.org/10.15823/sm.2018.5

Pulsometric Analysis of the Functional State of Cardiovascular System in Humans

Application of the method of arterial piezopulsometry to studying the individual characteristics of the functional state of the cardiovascular system (CVS) in patients of different ages and health states is discussed. Development of a new algorithm for the two-channel simultaneous analysis of the parameters of blood pressure pulse wave plots recorded by two piezoelectric transducers has allowed us to perform a comparative analysis of cardiohemodynamics in different arteries, as well as to evaluate the elasticity of their walls and the nature of the autonomic regulation of CVS effectors with high accuracy. This comprehensive analysis enhances the predictive value of early pulsometric diagnostics of the individual functional state of CVS in humans.

Разработка решающего правила для оценки функционального состояния сердечно-сосудистой системы на основе компьютерного анализа экг при проведении медосмотров

Разработка решающего правила для оценки функционального состояния сердечно-сосудистой системы на основе компьютерного анализа экг при проведении медосмотров

Analysis of adaptation potentials of kick boxers’ cardio-vascular system

Analysis and assessment of athletes’ adaptation potential are important components of effective selection and prediction of sports successfulness. Purpose: study and analysis of kick boxers’ cardio-vascular system’s adaptation potentials under standard physical load and in recreation. Material: in the research kick boxers (n=17, students) participated. The athletes were divided into 2 groups, depending on reaction to physical load: 1st group - athletes with normotonic type of reaction (n=9, age 17.56±0.80 years); 2nd group - athletes with reaction different from normotonic (n=8, age18.25±0.88 years). Indicators of cardio-vascular reaction type and tolerance to physical load were found with the help of PWC170 test. Results: we confirmed similarity of kick boxers’ reaction to physical load. After 1st stage of physical load heart beats rate was noticeably lower in the 1st group. After 2nd stage of load systolic blood pressure was lower in the 1st group. After load, in the 1st group heart beats rate and systolic BP restored quicker. Reduction of heart beats rate under load in 1st group can serve as a proof of better adaptation mechanisms. Conclusions: training of athletes with periodic control of electric cardiogram under physical loads permits to assess functional state of cardio-vascular system; its adaptation and correspondence to definite physical loads. Such approach permits not to admit progressing of cardio-vascular system’s pathological state.

Functional state of the cardiovascular system in 13-year-old adolescents with different types of autonomic nervous regulation

The features of the functional state of cardiovascular system in 13-year-old children with different types of autonomic nervous regulation were studied. Children with normotonic and parasympathetic types of autonomic regulation were found to have the highest adaptation capacities. The autonomic nervous system influences the bioelectrical processes in myocardium, the duration of cardiac cycle phases, and cerebral blood flow. Schoolchildren aged 13 years with higher sympathetic activity have shorter duration of the cardiac cycle, the phase of isometric contraction, and diastole. They have a lower pulse blood flow rate and a higher tone of large and medium cerebral vessels. No relationship was revealed between the initial autonomic nervous regulation of heart rate and the type of adaptation of myocardium to physical dynamic loads, as well as the type of adaptation of cerebral circulation to mental stress.