Functional Independence Measure Index Research Articles

Impact of Tailored Intensive Rehabilitation on Functional Independence and Quality of Life in Brain Tumor Patients: A Prospective Observational Study

Background: Brain tumors are a heterogeneous group causing disability. They significantly impact functional independence and quality of life. This study aims to investigate how tailored intensive rehabilitation affects brain tumor patients using the functional independency measure score.
 Materials and Methods: This is a prospective observational correctional study conducted in the department of Neurophysiotherapy and Neurosurgery at Nobel Medical College Teaching Hospital, Biratnagar over a period of 18 months. A total of 96 brain tumor patients who underwent surgery at a tertiary care centerduring the study period were included. Along with the demographic data, the diagnosis ofbrain tumor functional independency was assessed using the Functional Independence Measure Index.
 Results: A total of 96 brain tumor patients (44 males, 52 females, average age 55.6 years) were studied. The tumors' distribution showed variations, with glial tumors being the most frequent (36.4%). The Functional Independence Measure (FIM) Index was used to assess functional independence, yielding an average score of 82.5. Patients with meningioma had higher FIM scores (84.3) compared to glial cell tumor patients (80.1), although not statistically significant (p = 0.122).The study also explored correlations between FIM scores, hospital stay duration (average 9 days), and patient satisfaction. A weak positive correlation (r = 0.25) existed between FIM scores and hospital stay duration.A moderate positive correlation (r = 0.65) was found between FIM scores and patient satisfaction, suggesting higher satisfaction among patients with better functional independence.
 Conclusion: Intensive rehabilitation therapy shows promise in improving functional independence in brain tumor patients.

Procjena uspješnosti protetičke rehabilitacije osoba s amputacijom donjeg uda

Cilj: Protetička rehabilitacija nakon amputacije donjeg uda uključuje sve kompleksne postupke i interakcije rehabilitacijskog tima i pacijenta koje su usmjerene cilju uspostavljanja sigurnog i stabilnog hoda s protezom. Nakon otpuštanja iz rehabilitacijskog centra pacijent koristi protezu, sukladno dobi, stilu života i okolini u kojoj živi. Cilj: Cilj rada je procijeniti uspješnost protetičke rehabilitacije osoba s amputacijom donjeg uda koristeći indekse predviđene mobilnosti pacijenta (engl. Amputee Mobility Predictor; AMP) i brzinu hoda. Ispitanici i metode: U radu su korišteni podaci pacijenata iz baze podataka Zavoda za fizikalnu i rehabilitacijsku medicinu Kliničkog bolničkog centra u Rijeci, a pri tome su u skladu s Helsinškom deklaracijom ostali anonimni: dob, spol, vrsta i strana amputacije, AMP, brzina hoda i vrijeme provedeno u protezi. Od sto pacijenata s amputacijom 62 su bila transtibijalna (TT) i 38 transfemoralna (TF). U ispitivanju je sudjelovalo 27 žena i 73 muškarca. Svim pacijentima je utvrđen AMP indeks prije rehabilitacijskog postupka (AMPnoPRO) te nakon završenog rehabilitacijskog postupka (AMPPRO). Rezultati: Nakon provedene protetičke rehabilitacije utvrđena je statistički značajna razlika u konačnoj mobilnosti (AMP: p < 0,001) i brzini hoda (p = 0,002) između TT i TF grupa, odnosno bolji rezultat su postigli pacijenti s nižom razinom amputacije (TT). Također je utvrđena statistički značajna povezanost između vremena provedenog u protezi i brzini hoda te AMP indeksa (p < 0,001). Zaključak: Razina amputacije je važna stavka koja pridonosi konačnom ishodu rehabilitacijskog postupka, odnosno viša razina amputacije kod pacijenata (TF) predstavlja jedan oblik ograničenja za bolji uspjeh u odnosu na pacijente s nižom razinom amputacije (TT).

Effectiveness of repeated transplantations of hematopoietic stem cells in spinal cord injury.

To evaluate the short and long-term effects of the complex cell therapy of 202 cases of spinal cord injury (SCI). The main arm included 202 cases of SCI and the control arm included 20 SCI cases. For the therapy the hematopoietic stem cells (HSCs) and progenitor cells (PCs) were mobilized to peripheral blood by 8 subcutaneous injections of granulocyte colony-stimulating factor (G-CSF) for 4 d and are harvested at day 5. The cells were administered to the main arm intrathecally every 3 mo for a long term (3-5 years) according to the internal research protocol international medical institute of tissue engineering. Magnetic resonance imaging of the site of injury and urodynamic tests were performed every 6 mo. Motor evoked potentials (MEP), somatosensory evoked potentials (SSEP) were evaluated every 3 mo. The patients were evaluated with american spianl injury association (ASIA) index, functional independence measure index, the Medical Research Council Scale, the International Standards for Neurological Classification of Spinal Cord Injury (ISCSCI-92) and specifically developed scales. The function of bladder was evaluated by a specifically developed clinical scale. The long-term clinical outcomes were assessed for the SCI patients who received no less than 20 intrathecal transplantations of HSCs and hematopoietic precursors (HPs). The restoration of neurologic deficit after HSCs and HPs transplantations was proved stable and evident in 57.4% of the cases. In 42.6% cases no neurologic improvement has been observed. In 50% of the cases the motor restoration began after the first transplantation, which is confirmed in average by 9.9 points improvement in neurologic impairment as compared to the baseline (P < 0.05). Repair of the urinary system was observed in 47.7% of the cases. The sensitivity improved from baseline 124.3 points to 138.4 after the first and to 153.5 points after the second transplantations of HSCs and HPs (P < 0.05, between the stages of research). The evaluation with ASIA index demonstrated regress of neurologic symptoms in 23 cases. Motor progress was also assessed with the ISCISCI-92 motor and sensory scores, and the data coincided with those received with the specifically developed scale. The number of the patients with the signs of locomotive repair was 56.9%. No life threatening complications or adverse effects have been observed. The method is safe, effective and considerably improves the life quality of SCI patients. The therapy is approved for clinical use as the treatment of choice.