I will summarize several TMS applications in movement disorders. Function of supplementary motor area (SMA) and preSMA revealed by QPS (Shimzu T et al). We studied functional differences between the pre-SMA and SMA in sequence learning in humans. To induce LTP/LTD, we administered quadripulse transcranial magnetic stimulation (QPS) with an inter-stimulus interval of 5 or 50 ms (QPS-5/50) over the pre-SMA or SMA in healthy volunteers. QPS-5 over the pre-SMA increased the error rate without any changes in movement speed. When administered over the SMA, QPS affected the rate of reaction time reduction across trials without any changes in the error rate. Cerebellar involvement and cerebellar stimulation treatments. Essential tremor (Hanajima et al). Several lines of evidence suggested a cerebellar pathophysiology of essential tremor (ET). It was recently confirmed by human pathology, neuroimaging studies and others. This hypothesis was also confirmed by cerebellar TMS over cerebellum (cerebellar inhibition: CBI) and prism adaptation task in ET patients (Hanajima et al). Cerebellar stimulation treatments in movement disorders (Çan, M et al). Many researchers have been interested in cerebellar involvement in movement disorders and also cerebellar stimulation as one of treatment methods. However, our magnetic coil must activate cerebellum in some extent but not purely cerebellum alone, and always activate some other structures. The simulation study showed considerable amount of currents must be induced in the cerebellum even with a small coil. Cerebellar stimulation is one of future projects of TMS. Transcranial focused ultrasound stimulation (tFUS). Very low intensity tFUS makes reversible functional changes in human brain. This reversible modulation is used for functional studies of human brains. Its focality and ability to induce functional changes in deep brain structures, such as thalamus, must enable this method to be used in movement disorders. Alternative leg movements induction by lumbar rTMS (Nishimura et al). The lumbar gait center is known to produce gait-like alternative leg movements in animals. We made a system to voluntary induce a gait-like leg movement triggered by her/his own upper limb EMGs. This system induced alternative leg movements, gait like movements, in patients with paraplegia due to spinal cord injury.