Function In Patients Research Articles

Research Progress on the Application of Nanomaterials in Bone Defect Repair

Bone defects refer to the loss or damage of bone tissue, commonly occurring due to trauma, tumor resection, infection, and non-union fractures. Clinically, bone defects not only affect the patient's function and quality of life but may also lead to chronic pain, mobility impairment, and psychological issues. Repairing large bone defects remains challenging, and traditional treatment methods such as autologous and allogeneic bone grafting face difficulties related to donor site morbidity, postoperative complications, and poor bone healing. Therefore, the development of novel bone repair materials has become a research focus. Nanomaterials, due to their unique physicochemical properties, such as high specific surface area, excellent biocompatibility, and tunable mechanical properties, are increasingly being applied in the field of bone repair. Nanoparticles can enhance the mechanical properties of matrix materials, improving the strength and toughness of bone repair constructs and promoting the proliferation and differentiation of bone cells. Furthermore, nanomaterials can facilitate bone regeneration by releasing bioactive factors or modulating the microenvironment. Consequently, the application of nanomaterials in bone repair holds significant promise. This review aims to summarize the recent research on the application of nanomaterials in the field of bone defect repair.

Comparison of clinical outcomes and cost-utility between unilateral biportal endoscopic discectomy and percutaneous endoscopic interlaminar discectomy for single-level lumbar disc herniation: a retrospective matched controlled study

ObjectiveThis study aimed to compare the efficacy and cost-utility of unilateral biportal endoscopy (UBE) versus percutaneous endoscopic interlaminar discectomy (PEID) for the treatment of single-level lumbar disc herniation (LDH).MethodsA retrospective analysis was conducted on 99 patients who underwent either UBE (n = 33) or PEID (n = 66) between July 2022 and December 2023 at the Second Xiangya Hospital. Patients were matched 1:2 based on age, sex, and surgery level to ensure comparability. Clinical outcomes were assessed using Visual Analog Scale (VAS), European Quality of Life-5 Dimensions (EQ-5D), and Oswestry Disability Index (ODI) scores, with quality-adjusted life years (QALYs) calculated for cost-utility analysis. Hospitalization costs were analyzed, and the incremental cost-utility ratio (ICER) was determined.ResultsBoth UBE and PEID groups demonstrated significant postoperative improvements in VAS, EQ-5D, and ODI scores (p < 0.05). The operative time, blood loss and nursing cost were significantly higher for UBE compared to PEID (p < 0.05). UBE has higher gained QALY and overall costs, but the differences are not statistically significant (p = 0.643 for QALY, p = 0.327 for costs). The Incremental Cost-Effectiveness Ratio (ICER) for UBE compared to PEID was calculated to be $354.5 per QALY gained, indicating that for each additional QALY gained through UBE, an additional cost of $354.5 is incurred compared to PEID.ConclusionIn our single-center study conducted in China, both the UBE and PEID procedures have demonstrated comparable short-term efficacy in alleviating pain and improving functional ability in patients with single-level LDH. UBE procedure demonstrates greater cost-utility than the PEID procedure in cost-utility analysis, despite its longer operative time, higher nursing costs and greater blood loss.

Maximizing the "Functional" in the Functional External Memory Aid Tool for Patient-Centered Treatment Planning in Mild Cognitive Impairment.

The Functional External Memory Aid Tool (FEMAT) is an 11-item performance-based measure that simulates everyday tasks (e.g., medication management) to measure one's use of compensation (e.g., pill organizer). The FEMAT is not a norm-referenced diagnostic tool; rather, it is designed to provide clinicians with information about a patient's function and compensation in a standardized format. To provide further evidence for validity of the FEMAT, the purpose of this study was to conduct a mixed-methods analysis of FEMAT responses to operationalize the types of behaviors elicited during test administration. We adopted an embedded single-case study design to analyze the FEMAT administrations of 12 community-dwelling female participants, ages 73-90 years, who met criteria for mild cognitive impairment. These participants were part of the original validation sample during which they completed the FEMAT (Version 1.0) in a single session with an assessor. Sessions were video-recorded and transcribed. We analyzed the data qualitatively in two phases using theme and subtheme codes and then quantitatively analyzed the data for response trends. Our thematic analysis revealed four themes to operationalize participants' verbal and behavioral FEMAT responses: (a) used an external memory aid (EMA), (b) described using a strategy, (c) discussed memory and comprehension, and (d) discussed functional information. While completing the FEMAT, most participants described using a strategy (85%) and discussed their self-perceived memory and comprehension (33%). Several subthemes also emerged within each theme (e.g., self-perceived memory strengths and barrier). Our analysis suggests that beyond a 4-point item score, the FEMAT elicits behavioral (e.g., used an EMA) and verbal (e.g., discussion of health information) content that may be useful for person-centered treatment planning. This study is part of a comprehensive research agenda establishing the evidence for the validity of the FEMAT to support its use to inform person-centered treatment approaches.

Functional outcomes in anterior talofibular ligament repair with anchoring screw: Two case series

Background: The Anterior Talofibular Ligament (ATFL) functions to resist plantarflexion and anterolateral translation of the talus. Lateral ankle sprains account for 85% of all ankle sprains and are most common in athletes. ATFL injury is the most common ankle ligament injury, accounting for 35.6% of the total patients with ligament injuries. Case Report: The first patient, a 39 year old man with a diagnosis of ATFL injury, had a history of falling with the outside of his right leg supported when he fell. Physical examination of the right ankle revealed tenderness in the posterolateral region, pain during dorsiflexion and plantarflexion, positive anterior drawer examination and positive talar tilt. The second patient, a 19 year old male with the same history and injury location on the right ankle. Physical examination showed a similar condition to the first patient. MRI examination of both patients showed ATFL injury. Both patients underwent open repair of the right ATFL (Brostrom technique) with anchoring screws, post-operative care, and evaluation one year after surgery. Discussion: Surgery is taken to prevent repeated ruptures, especially in cases of ligament tears. The Brostrom technique is an anatomical repair with end-to-end repair from the final ATFL tear to the distal anterior fibula. Both patients demonstrated normal foot and ankle function, with a score of 100 based on the American Orthopedic Foot Ankle Association (AOFAS). Conclussion : Brostrom open repair with Anchoring Screw is an effective procedure in returning the patient's function to its previous level as assessed based on the AOFAS score after a year after surgery.

The impact of rehabilitation on the recovery of executive functions in stroke patients with different location of the ischemic focus.

Cognitive dysfunction is part of the clinical picture of stroke. Most of the executive dysfunctions are diagnosed in the early stage of rehabilitation, a few weeks after the vascular incident. Coexistence of executive dysfunctions with other disorders in stroke patients may hinder patient's functions, slow down the rehabilitation process, and disrupt self-awareness, interpersonal communication, and professional activity in everyday life. Ninety patients after ischemic stroke were examined (right hemisphere stroke: N = 33, left hemisphere stroke: N = 57). The study group (N = 45) consisted of patients rehabilitated in the Department of Rehabilitation and Physical Medicine of the University Teaching Hospital of the Military Medical Academy in Lodz, Łódź, Poland, in whom a comprehensive neurorehabilitation program was implemented, consisting of motor and neuropsychological rehabilitation. The control group (N = 45) consisted of patients awaiting admission to the department, who were covered by comprehensive environmental rehabilitation including exercise therapy and neuropsychological therapy. Executive function was measured with 3 popular diagnostic tools: the Wisconsin Card Sorting Test (WCST), the Trail Making Test (TMT part A, TMT part B), and the letter test and category test with the Verbal Fluency Test (VFT). The tests were carried out twice: the first time before the start of rehabilitation and 5 weeks later after its completion. Although patients with right-hemispheric stroke showed better improvement in executive functions, stroke location did not prove to have significant impact on how effective the rehabilitation was. Right hemisphere stroke patients showed greater improvement in restoring executive functions after rehabilitation compared to left hemisphere stroke patients. The location of the stroke did not significantly correlate with the efficiency of the rehabilitation setting. Int J Occup Med Environ Health. 2024;37(4):452-67.

Comparing the effectiveness of Muscle energy technique, positional release technique and conventional therapy on pain,range of motion and functional ability in patients with mechanical low back pain

BACKGROUND OF THE STUDY:Low back pain is one of the most common health problem and 80 percent of the people experiences low back pain in their lifetime. Majority of low back pain is due to the muscle imbalance. Muscle imbalance occurs due to shortened or lengthened in structure and it leads to injury which causes changes in motor programming. OBJECTIVE: To compare the effects of Muscl Energy Technique, positional release technique and conventional therapy on improving pain, range of motion and functional ability in patients with mechanical low back pain. SUBJECTS AND METHODS:Twenty four patients of complaining of mechanical low back pain participated in the study. Patients were randomly allocated using computer generator software into three groups: group A which recieved Muscle energy technique, group B which recieved Positional release technique and group C which recieved conventional therapy. Treatment sessions were given three times per week for three weeks. Patients were assessed before and after treatment using Numerical Pain Rating Scale(NPRS), Modified Oswestry Disability Index(MODI), and Modified Schober's Test to assess pain severity, functional ability and range of motion of lumbar spine respectively. RESULTS: Based on this statistical analysis, Group A showed better Statistical significance in NPRS, MODI and ROM mean value as compared to Group B and C. Hence alternate hypothesis is accepted and null hypothesis is rejected. This we conclude that Muscle energy technique is more beneficial compared to Positional release technique and conventional therapy. Conclusion: Muscle energy technique and conventional therapy groups shows significant improvement on pain and lumbar extension range of motion compared to Positional release technique, whereas there was no significant difference in MODI on muscle energy technique, positional release technique and conventional therapy

Complicated Pleural Infection is Associated With Prolonged Recovery and Reduced Functional Ability.

Management of complicated pleural infections (CPIs) had historically been surgical; however, following the publication of the second multicenter intrapleural sepsis trial (MIST-2), combination tissue plasminogen (tPA) and dornase (DNase) offers a less invasive and effective treatment. Our aim was to assess the quality of life (QOL) and functional ability of patients' recovery from a CPI managed with either intrapleural fibrinolytic therapy (IPFT) or surgery. We identified 565 patients managed for a CPI between January 1, 2013 and March 31, 2018. There were 460 patients eligible for contact, attempted through 2 phone calls and one mailer. Two questionnaires were administered: the Short Form 36-Item Health Survey (SF-36) and a functional ability questionnaire. Contact was made in 35% (159/460) of patients, and 57% (90/159) completed the survey. Patients had lower QOL scores compared to average US citizens; those managed with surgery had higher scores in physical functioning (surgery: 80, IPFT: 70, P=0.040) but lower pain scores (surgery: 58, IPFT: 68, P=0.045). Of 52 patients who returned to work, 48% (25) reported an impact on their work effectiveness during recovery, similarly between management strategies (IPFT: 50%, 13/26 vs. surgery: 46%, 12/26; P=0.781). Patients with a CPI had a lower QOL compared with average US citizens. Surgically managed patients reported improved physical functioning but worse pain compared with patients managed with IPFT. Patients returned to work within 4 weeks of discharge, and nearly half reported their ability to work effectively was impacted by their recovery. With further research into recovery timelines, patients may be appropriately counselled for expectations.

The effectiveness of Transcutaneous Electrical Nerve Stimulation and strengthening exercises on the functional ability of patients with osteoarthritis of the knee joints: A case report

Knee osteoarthritis (OA) is the most common musculoskeletal disease among elderly individuals. It affects the ability to sit on a chair, stand, walk, and climb stairs. Our objective was to evaluate the effectiveness of tens and strengthening exercises on functional ability in patients with OA of knee joints. We present a case of a 55-year-old female housewife with bilateral knee pain, which manifested suddenly as a dull ache exacerbated by walking and stair climbing and alleviated by rest. Clinical examination revealed crepitus, grade 1 tenderness, and reduced range of motion (ROM) in the left knee. The radiographic evaluation confirmed grade 3 osteoarthritis according to the Kellgren and Lawrence grading system, indicating moderate multiple osteophytes, definite joint space narrowing, some sclerosis, and potential bone deformity. The patient underwent a 4-week intervention comprising strengthening exercises and TENS. Pain intensity was assessed using the Numeric Pain Rating Scale (NPRS), knee ROM with a goniometer, and functional limitations with the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC). Assessments were conducted weekly throughout the intervention. The findings suggest that the combined application of TENS and strengthening exercises effectively alleviates pain and improves functional ability in patients with knee osteoarthritis.

Behavioral Management in the Rehabilitation of a Person with Severe Mental Illness: The Path Less Travelled.

In severe mental illness (SMI), such as schizophrenia, rehabilitation begins immediately. Aside from the token economy, there is limited literature on behavioral modification (BM), which is a crucial aspect of rehabilitation for person with severe mental illness (SMI). We demonstrate the implementation and effectiveness of BM for one year in managing behavioral difficulties in a person with SMI. The direct observation method and the ABC functional analysis model were used for evaluation. Management, such as reinforcement and punishment, was implemented. Pre- and postassessments revealed a considerable decrease in problematic behaviors. This article also highlights the obstacles faced while managing the case and caregiver burden in rehabilitation. In persons with SMI, the application of BM enhances the patient's functionality and reduces the caregiver burden.

The Essex-Lopresti Injury.

The classic Essex-Lopresti injury (ELI) pattern is a radial head fracture and disruption of the central band, which compromises the longitudinal radioulnar relationship. Delayed recognition and inappropriate treatment of ELI can be devasting to a patient's function. The recent literature has demonstrated an improved understanding of the mechanism of ELI. This has facilitated early diagnosis, appropriate treatment, and compelling outcomes. Further investigation will contribute to the standardization of treatment methods and algorithms for concomitant injury.

ICF-based hearing and functioning assessment: validation and research outcomes of utilizing the HEAR-COMMAND tool for patients with mild to moderately severe hearing loss and individuals with normal hearing.

Current clinical assessments for Hearing Loss (HL) are often limited to controlled laboratory settings in which a narrow spectrum of hearing difficulties can be assessed. A majority of the daily life challenges caused by HL cannot be measured in clinical methodologies. To screen the individuals' needs and limitations, a questionnaire named the HEAR-COMMAND tool was developed and qualitatively validated through an international collaboration, aligning with the World Health Organization's International Classification of Functioning, Disability, and Health Framework (ICF) Core Sets for Hearing Loss. The tool empowers healthcare professionals (HCPs) to integrate the ICF framework into patient assessments and patient-reported outcomes (PRO) in clinical and non-clinical settings. The aim is to provide a general foundation and starting point for future applications in various areas including ENT and hearing acoustics. The outcome can be employed to define and support rehabilitation in an evidence-based manner. This article presents the validation and research outcomes of using the tool for individuals with mild to moderately severe HL in contrast to normal-hearing individuals. Using a cross-sectional multicenter study, the tool was distributed among 215 participants in Germany, the USA, and Egypt, filled in German, English, or Arabic. Three outcome scores and the corresponding disability degree were defined: hearing-related, non-hearing-related, and speech-perception scores. The content and construct validation were conducted, and the tool's internal consistency was assessed. The extracted constructs included "Auditory processing functionality", "Sound quality compatibility", "Listening and communication functionality", "Interpersonal interaction functionality and infrastructure accessibility", "Social determinants and infrastructure compatibility", "Other sensory integration functionality", and "Cognitive functionality". Regarding content validity, it was demonstrated that normal-hearing participants differed significantly from individuals with HL in the hearing-related and speech-perception scores. The reliability assessment showed a high internal consistency (Cronbach's alpha = 0.9). The outcome demonstrated the HEAR-COMMAND tool's high content and construct validity. The tool can effectively represent the patient's perspective of HL and hearing-related functioning and enhance the effectiveness of the treatment plans and rehabilitation. The broad range of targeted concepts provides a unique overview of daily life hearing difficulties and their impact on the patient's functioning and quality of life.

Effects of Traditional Chinese Medicine acupuncture combined with rehabilitation nursing on improving recovery of limb motor function and self-care ability of stroke patients with hemiplegia

Effects of Traditional Chinese Medicine acupuncture combined with rehabilitation nursing on improving recovery of limb motor function and self-care ability of stroke patients with hemiplegia

Effectiveness of extracorporeal shock wave therapy on functional ability in grade IV knee osteoarthritis – a randomized controlled trial

Extracorporeal shockwave therapy (ESWT) is a non-invasive physical therapy intervention that has emerged in the recent past to address the upswing of osteoarthritis (OA). However, insufficient evidence is present to prove the efficacy of ESWT on grade IV knee osteoarthritis (KOA). The present study aimed to examine the effects of ESWT on functional ability in patients suffering from grade IV KOA. Thirty volunteers aged 45–60 years with grade IV primary KOA diagnosed by an orthopaedic surgeon based on the Kellgren-Lawrence score participated in the study. The participants were equally and randomly divided into two groups (i.e. experimental and control), with 15 participants in each group. The participants in the control group performed conventional physiotherapy (CPT) that included ultrasound therapy, isometric quadriceps, SLR and isometric hip adductor strengthening exercises. The participants in the experimental group received ESWT in addition to CPT. Lower extremity functional scale (LEFS) score was measured before and after the four weeks of intervention. In both groups, a statistically significant (p = 0.001) improvement in LEFS was observed. In the experimental groups, it improved by 81.92% and in the control groups by 48.15%. A statistically significant (p < 0.001) difference was observed in LEFS post-intervention values between both groups. As demonstrated by our trial results, the addition of ESWT to the CPT program will yield beneficial results in ameliorating the functional disability in patients with primary KOA (grade IV). Further studies are needed to confirm and apply these findings to a larger cohort.

Reconstruction of Chronic Monteggia Fracture with Radial Head Excision: A Case Report

Introduction: Chronic Monteggia fracture is a rare and clinically challenging condition, characterized by a non-union fracture of the proximal ulna with dislocation of the radial head. This case report presents the case of a 42-year-old woman with a chronic Monteggia fracture diagnosed 21 years after the initial injury, highlighting the importance of a careful patient history and radiographic investigation. Case presentation: A 42-year-old woman presented with left elbow pain and a history of significant trauma 21 years previously. Physical examination revealed limited range of motion and radiographic examination revealed a nonfused fracture of the proximal ulna with dislocation of the radial head. The patient underwent open reduction and internal fixation (ORIF) reconstruction of the ulna and excision of the radial head. Conclusion: Successful surgical reconstruction of chronic Monteggia fractures results in significant improvements in the patient's function and quality of life. This case report emphasizes the importance of early diagnosis and timely surgical intervention to prevent long-term complications and achieve optimal functional outcomes.

An Investigation Comparing the effects of Muscle Energy Techniques and Myofascial Release on Discomfort and Functional Ability in Patients with Lateral Epicondylitis - A Pilot Study

An Investigation Comparing the effects of Muscle Energy Techniques and Myofascial Release on Discomfort and Functional Ability in Patients with Lateral Epicondylitis - A Pilot Study

EFFECT OF CUPPING THERAPY ON PAIN, CARDIORESPIRATORY PARAMETERS, AND LUNG FUNCTION IN PATIENTS WITH FIBROMYALGIA SYNDROME

Background: The rheumatic condition fibromyalgia syndrome (FMS) is marked by extensive pain, and tender points, with accompanying complaints such as stiffened muscles, depression, anxiety, sleep disturbance, along with dyspnea, exhaustion, and other cardio-respiratory related dysfunction. This study’s goal was to determine the effect of dry cupping intervention on pain, cardiorespiratory parameters as well as lung function in patients with FMS. Methods: Thirty females with FMS (40–60 years old) were enlisted and subsequently divided into two distinct groups: conventional treatment with ([Formula: see text] = 15) and without ([Formula: see text] = 15) cupping therapy i.e. experimental and control groups respectively. All participants received therapies 3 days a week during this study. Visual Analogue Scale (VAS), digital pressure pain threshold (PPT), cardiac parameters including blood pressure using a sphygmomanometer, O2 saturation and pulse rate using a pulse oximeter, respiratory parameters including chest expansion using a measuring tape, lung functions including FVC and FEV1/FVC using a spirometer were used to assess participants on baseline, last day of 2nd and 4th week of treatment. Results: Improvements in pain, PPT, oxygen saturation, pulse rate, and chest expansion, FVC and FEV1/FVC were higher in the group who got cupping therapy including conventional treatment against the group who just received conventional treatment ([Formula: see text] 0.05). At the end of the 4th week, there was no appreciable change in blood pressure levels between the groups ([Formula: see text] 0.05). Conclusion: The FMS treatment plan should include cupping therapy in addition to conventional treatment to help patients improve their cardio-respiratory fitness and overall quality of life.

Neuroinfectious Emergencies.

This article describes nervous system infections and complications that lead to neurologic emergencies. New research on the use of dexamethasone in viral and fungal infections is reviewed. The use of advanced MRI techniques to evaluate nervous system infections is discussed. Neurologic infections become emergencies when they lead to a rapid decline in a patient's function. Emergent complications may result from neurologic infections that, if not identified promptly, can lead to permanent deficits or death. These complications include cerebral edema and herniation, spinal cord compression, hydrocephalus, vasculopathy resulting in ischemic stroke, venous thrombosis, intracerebral hemorrhage, status epilepticus, and neuromuscular respiratory weakness.

Clinical and Functional Effects of Rehabilitation of Patients after COVID-19 Infection.

Background/Objectives: The most common post-acute consequences of SARS-CoV-2 include lung dysfunction, the impairment of cognitive functions and mental health, as well as the impairment of the musculoskeletal system in the form of fatigue and muscle weakness. Post-COVID-19 patients often experience impaired balance and reduced physical capacity. It is important to implement a rehabilitation program that eliminates the side effects of COVID-19 and allows for significant improvement in the patient's functionality. The aim of our study was to assess patient functionality after a 6-week rehabilitation program on balance, foot pressure distribution, and physical capacity in post-COVID-19 patients. Methods: The clinical study group consisted of 53 people 3 months after COVID-19 infection, confirmed by a positive PCR test. Exclusion from the study included people with comorbidities that impaired balance and gait. The patients underwent a posturographic assessment-Romberg test, a baropodometric assessment-static and dynamic, and a performance assessment-a 6 min walk test determining shortness of breath on the mMRC scale, blood pressure, heart rate, and saturation. Patients participated in rehabilitation until the sixth week, after which they were assessed again. Comparisons were made using IBM SPSS Statistics 27.0 software using the Wilcoxon pairwise order test, at a significance level of p < 0.05. Results: The result of the postural control assessment showed an improvement in the ability to maintain the centre of gravity in terms of the foot support area-statistical decreases were observed in the ellipse area, from 745.28 mm2 to 453.52 mm2 (p = 0.009), as well as maximum (from 3133.5 gr/cm2 to 2994.2 gr/cm2; p = 0.065) and average load on the left foot (from 1010.1 gr/cm2 to 969.38 gr/cm2; p = 0.028). In the 6 min walk test before and after exercise, the heart rate decreased after the therapy (shortness of breath on the mMRC scale also decreased from 79.12 to 74.95). This means that patients achieved better physical fitness and efficiency. Conclusions: Rehabilitation significantly improved balance, as measured by a decrease in ellipse area during the Romberg test.

Pengaruh Kombinasi Slow Deep Breathing dan Cryotherapy terhadap Nyeri Akibat Tusukan Fistula Arteriovenosa Pada Pasien Hemodialisis: Case Report

A problem often experienced by hemodialysis patients is pain when puncturing an arteriovenous fistula. Hemodialysis patients with AVFs experience an average of ten AVF punctures every month, lasting their entire lives. Persistent pain can negatively affect a patient's health, functional ability, and quality of life. This research uses a Case Report approach with nursing care. The intervention was carried out on a scale with structured data collection using the Numeric Scale Rating. The aim of this study was to examine the effect of a combination of slow deep breathing and cryotherapy on arteriovenous fistula puncture. This case study carried out data collection through interviews, intervention, evaluation and documentation. The results of this case study showed that the combination of Slow Deep Breathing and Cryotherapy was effective in reducing pain due to AV fistula puncture in hemodialysis patients. Before the intervention was carried out, the pain scale for both respondents was 6 (moderate pain), but after the intervention with Slow Deep Breathing and Cryotherapy for 4 sessions for 15 minutes, the pain scale decreased to 2 (mild pain).

Osteotomy Le fort I as a Treatment option for class III Dentoskeletal Problem

Introduction: Orthognathic surgery is surgery to correct the jaw relation and which aim to correct dentoskeletal deformities and a treatment option for severe deformity that cannot be corrected by orthodontic treatment alone. Le fort I osteotomy is a technique in orthognathic surgery that aims to correct the maxilla. In its management, it is possible for correction of the maxilla and mandible to achieve an optimal jaw relation, function and esthetics. Case report: This case report explained a patient with maxilla retrognathism accompanied by function and aesthetic problems. This patient was diagnosed with class III dysgnathy and was performed orthognathic surgery treatment with le fort I osteotomy technique under general anesthesia at Central Operating Theater at Hasan Sadikin General Hospital, Bandung, and was evaluate periodically after the surgery. Conclusion: In this case, the patient's function and aesthetic problems was corrected without causing any postoperative complications. Careful planning with a good calculation and treatment plans are important for obtaining a good result. Keywords: Le fort I osteotomy, class III disgnathy, dentoskeletal deformity