Full Sense Research Articles

Towards dynamic multiscale feedback during the injection moulding cycle of plastics

Injection moulding is a very popular technology for shaping plastics. Its history stretches back to the nineteenth century, and, as a consequence, it has developed outside the framework of digitisation. In order to fully implement the concepts of Industry 4.0, we need to update these legacy technologies so that they can fully benefit from the developments inherent in the “Internet of Things” and allow the process of injection moulding to take full advantage of digital optimisation so that it can fit effectively in the digital factory. In this work, we explore the quantitative use of X-ray scattering as a technology that can provide dynamic and multiscale feedback during the injection moulding cycle to be able to exploit digital twin technology as a means to optimise the operational parameters involved in injection moulding and to enable digital design of moulds in the fullest sense. This manuscript provides a way to mark future work and draw these possibilities to a wider audience.

U.S.–India defense cooperation: progress, motivation and constraints

AbstractDefense cooperation is an important pillar of the strategic partnership between the United States and India. Since the Modi government came to power in 2014, the defense cooperation between the United States and India has entered the fast lane. The two countries have made breakthroughs on multiple fronts, such as the signing of foundational agreements, the transfer of sensitive technologies, the joint research and development of advanced military equipment, and interoperability exercises. The deepening of defense cooperation reflects the two countries’ strategic convergence based on their respective national interests. Nevertheless, the structural gaps concerning their ideology, strategic goals, and industrial capability will pose limits on their cooperation. Therefore, it is unlikely that the United States and India will become a military alliance in the full sense, but rather the two sides will more likely adopt a quasi-alliance. Defense cooperation between the United States and India has become increasingly focused on targeting China, creating real challenges for China's national security.

Front Office Attendant Proactive Work Behavior

This study aims to determine the implementation of proactive work behavior shown by Front Office Attendants at MLV Hotel. The data collection technique in this study was by conducting direct interviews with the Hotel Manager and Front Office Supervisor. This study uses qualitative descriptive data analysis techniques that refer to five indicators, namely high initiative, high sense of responsibility, adaptive ability, problem-solving ability, clear and measurable work goals. The results of this study indicate that not all front office attendants have implemented proactive work behavior optimally, especially in the indicators of high initiative at work and high sense of responsibility. MLV Hotel management is advised to provide rewards to front office attendants who have implemented proactive work behavior and also provide punishment to front office attendants who have not shown a full sense of responsibility at work.

Contributions of directors trained by the (former) Soviet Union to Vietnamese drama

The later directors who were trained in the former Soviet Union or studied in socialist countries such as Bulgaria and Romania had a solid foundation in theatrical theory and in the organization of performances according to the Stanislavsky system, a scientifi c theatrical theory system, an advanced and very valuable artistic method, of world stature. After having professional directors, the Vietnamese drama theater has undergone great changes. The directors have matured, and today's performances are much diff erent from the past. There is no longer a state of arbitrariness on theater, the actors have a full sense of responsibility towards the audience and towards the image of the character they play. The art of directing has had good achievements with the success of plays that have been widely welcomed by audience and recognized by people in the industry.

Anti-Obesity Effects of a Collagen with Low Digestibility and High Swelling Capacity: A Human Randomized Control Trial

Background/Objectives: Collagen is a protein formed by very long amino acid chains. When conveniently treated, it can incorporate water into the net, thus increasing its volume and mass. The present work aimed to evaluate the potential anti-obesity effects of bovine collagen that has been technologically treated to increase its water retention capacity in an acid pH medium, with the objective of inducing satiation. Methods: Collagen’s digestibility was tested with a pepsin digestion test. Its swelling capacity was tested in an acid pH medium simulating gastric conditions. Postprandial levels of ghrelin in response to collagen supplementation were tested in rats. In a randomized control trial, 64 subjects with overweight/obesity were allocated in two groups: supplemented daily with two protein bars enriched with collagen (20 g per day) for 12 weeks, or control group. Anthropometric and biochemical measurements were assessed in all the participants. Results: This collagen showed a low digestibility (<60%) and high swelling capacity (>1900%) in vitro. In humans with overweight and obesity, this collagen significantly reduced body weight, body mass index (BMI), systolic blood pressure (SBP), and fatty liver index (FLI) and increased fat-free mass when compared with the control group. A significant reduction in the sarcopenic index; total, troncular, and visceral fat (measured by DEXA); and serum leptin levels were observed in the collagen group at the end of the intervention, with no differences with respect to controls. Collagen reduced the sensation of hunger and increased fullness and satisfaction. In male Wistar rats, collagen decreased postprandial blood ghrelin levels. Conclusions: Collagen supplementation (20 g per day for 12 weeks) reduced body weight, BMI, waist circumference, fat mass, FLI, and SBP in humans with overweight and obesity, which might be related to the increased sensation of fullness and satisfaction reported by the volunteers after the intake.

Identifying correlations between nutritional impact symptoms and risk factors for malnutrition in adult cancer patients with solid tumors: a cross-sectional study from a developing country.

Many cancer patients experience malnutrition, which can worsen their health and survival outcomes. However, limited research exists in our region on how common malnutrition is among hospitalized adults with solid tumors and what factors contribute to it. This study aimed to identify these factors and assess the effects of nutritional impact symptoms (NISs) caused by solid tumors on patients' nutritional status. Between July 2022 and February 2023, a cross-sectional study was carried out on the campuses of two major cancer treatment centers located in a national university hospital and a governmental hospital. Twelve NISs were adopted from the Patient-Generated Subjective Global Assessments (PG-SGA). The Nutrition Risk Screening 2002 (NRS-2002) instrument was used to thoroughly assess the risk of malnutrition. Multiple linear regressions were used to conduct a thorough study. A cohort of 294 participants was included. The prevalence of malnutrition risk (NRS score ≥ 3) was 26.9%. Parameters such as age, gender, marital status, educational level, monthly income, type of cancer and treatment modality, and the need for mealtime assistance exhibited statistically significant associations with malnutrition (p < 0.05). The results revealed a substantial inverse correlation between fluid intake and the NRS-2002 score (p < 0.001). Furthermore, symptoms related to solid tumors and their treatment, including chewing difficulties, fatigue, dry mouth, anorexia, constipation, nausea, dizziness, and a sensation of fullness, were also significantly associated with malnutrition (p < 0.05). Additional insights from the regression analysis underscored the independent correlation between the risk of malnutrition in solid malignant malignancies and factors such as anorexia (p < 0.001), colorectal cancer (p = 0.003), gender (p = 0.018), educational attainment (p = 0.049), and the need for mealtime assistance among patients (p < 0.001). Malnutrition is a major issue among adult cancer patients, particularly those with solid tumors. Anorexia, colorectal cancer, gender, educational attainment, and the need for mealtime assistance were identified as factors that led to malnutrition in our research. This study emphasizes the need for a multidisciplinary plan of care to diagnose and treat malnutrition, improve overall therapy, and reduce mortality and morbidity.

Chronotopes of home and dislocation: recognising the lived experiences of refugees

ABSTRACT Forced migrants are often presented in public and private discourse from a reductive perspective focusing solely on their vulnerability and their status as refugees, without acknowledging other aspects of their identity and life history. This article investigates how refugee-background participants in qualitative research interviews drew on the chronotopes of home to construct a narrative of origin that foregrounded diverse aspects of their identity and emphasised their lived experiences in a fuller sense. In their narratives, participants contested representations of their home countries and of historical events, as well as representations of themselves, to challenge reductive identity constructions. Further, the narratives suggested that while widely known, mass-mediated chronotopes may assist in initial orientation to a location and event or time period, these generally provide a limited, and sometimes a highly contestable, representation of reality.

Glucagon-Like Peptide-1 (GLP-1) Receptor Agonists: Exploring Their Impact on Diabetes, Obesity, and Cardiovascular Health Through a Comprehensive Literature Review.

Glucagon-like peptide-1 receptor agonists (GLP-1-RAs) are a novel class of medications promising for treating type 2 diabetes mellitus (T2DM) and obesity-related conditions such as cardiovascular disease (CVD) and non-alcoholic fatty liver disease (NAFLD). This comprehensive literature review examines available research on these medications, focusing on their mechanisms of action, clinical effectiveness, safety profiles, and socioeconomic implications. A comprehensive search was performed using the PubMed, EMBASE, and Cochrane Library databases. Although initially developed for glucose management, these drugs have also demonstrated efficacy in promoting weight loss and reducing the risk of CVD. GLP-1-RAs function similarly to naturally occurring incretins. They stimulate insulin secretion in response to glucose levels, inhibit glucagon release, delay stomach emptying, and generate a sense of fullness via brain pathways. Head-to-head clinical studies have indicated that GLP-1-RAs outperform conventional antidiabetic medicines in terms of glycemic management and weight reduction. According to cardiovascular outcome studies, various drugs in this category have been found to reduce the frequency of severe adverse cardiovascular events. A common side effect is gastrointestinal toxicity, which can be mitigated by gradually increasing the dose. Personalized treatment is likely because the effectiveness, safety, and dose regimens of currently available GLP-1-RAs differ. GLP-1-RAs are a superior choice for patients with T2DM, especially those who already have CVD or require weight-control support. The high cost of these drugs creates hurdles to access and fair healthcare. Current research mainly focuses on increasing therapeutic uses and producing orally delivered medicines with greater potency and bioavailability. Integrating GLP-1-RAs into clinical practice can enhance patient outcomes and reduce the community burden of cardiometabolic disease.

The relationship of advocate investigation and evidence in criminal proceedings

The article examines the institution of a lawyer’s investigation in criminal proceedings, as well as the activity of a defense attorney in collecting evidence within the framework of criminal proceedings, which should be regulated as fully and qualitatively as possible (as far as possible) in order to implement such principles of criminal proceedings as the presumption of innocence, ensuring the suspect’s right for the defense, competition of the parties, and these principles should apply not only at the stage of the trial, but also at the stage of the pre-trial investigation. Attention is drawn to the fact that currently, in practice, in the absence of legislative regulation of the procedure for the inclusion of information collected by the defense counsel in the materials of criminal proceedings, the defense counsel has to make a reasoned request to officials who are conducting criminal proceedings. It is noted that evidentiary information collected by the defense attorney on his own without involving the materials of the criminal proceedings cannot be used in the process of proving and substantiating the position of the defense in the criminal proceedings, i.e. become evidence in the full sense of the word. In this regard, it is proposed to make changes to the Criminal Procedure Code of Ukraine regarding the procedure for the inclusion of information collected by the defense attorney in the materials of criminal proceedings, including the procedure for providing it by the defense attorney and the procedure for receiving it from the defense attorney by the inquirer, investigator, prosecutor, and court, specifying that no the right, and the duty of persons conducting pre-trial investigation in criminal proceedings to attach evidentiary information to the materials of criminal proceedings. It is pointed out the need for regulatory regulation of the specified legal relations in view of the importance of the development of the institution of evidence collection by the subjects of criminal proceedings, including the defense attorney; since his activity in this field is necessary for the practical implementation of the principle of adversarial criminal proceedings, equality of the parties, as well as for objective pre-trial investigation and trial of each specific criminal proceeding.

Surface and Depth: Reading Photographs in Obasan and The Invention of Solitude

Since its invention, photography has been imbued with the promise of providing a sense of fullness and has been believed to possess the unique capacity to capture the entirety of a moment. On the other hand, such assumed potentiality to capture all is yet found subject to the surface, and photography turns out to be a sort of art that lacks depth. This paper intends to focus on the tension between surface and depth in the representation of photographs in literature, a topic that is often neglected in literary studies. Through the theoretical lens of Walter Benjamin’s and Roland Barthes’s discourses on photography, this paper examines Joy Kogawa’s Obasan and Paul Auster’s The Invention of Solitude, both of which expose the discrepancy between what is visible on the surface and what lies beneath, as well as between what is within the frame and what exists beyond it. This paper is divided into two parts. The first part discusses how Benjamin’s and Barthes’s discourses on photography lead to the discussion of the surface and depth issues. The second part deals with the photographs in the two literary works, exploring how theoretical concepts of photography, including Benjamin’s “the optical unconscious” and Barthes’s “punctum,” will help shed light on them. By juxtaposing critical discourses on photography with these literary works, this paper concludes that their representation of photographs grapples with the tension between surface and depth and resonates with Benjamin’s and Barthes’s notions on photography.

The Use of Religious, Management, and Restorative Justice Models to Address Sexual Harassment in the Workplace

Sexual harassment in the workplace continues to produce organizational, financial, and human costs. For survivors, the investigative process may be adversarial, often leaving the individual without a full sense of recovery. Organizations may not provide survivors with the ability to verbalize their feelings or seek closure by directly addressing the offender. In addition, the perpetrator may not have the opportunity to listen to the survivor or share their remorse for their actions. What if after the organization’s investigation and the legal process were completed, both the survivor and the perpetrator engaged in a process that may lead to some healing and rehabilitation for the offender? This paper explores concepts found in various religious traditions, management concepts and restorative justice to offer such a process organizations may wish to consider. We propose a framework that extends beyond the tools in our human relations and legal system to offer survivors and offenders of workplace sexual harassment a possible path for healing, and perhaps, rehabilitation.

Sudden sensorineural hearing loss during pregnancy. A case study and literature review

&lt;b&gt;Introduction:&lt;/b&gt; Sudden sensorineural hearing loss (SSNHL) is defined as the sudden onset of hearing loss of 30 dB or more, across three consecutive frequencies in a pure-tone audiogram occurring within a 72-hour period. The term “sensorineural” indicates that the cause of the hearing loss lies in disturbances within the cochlea or auditory nerve. SSNHL typically presents as unilateral, transient hearing loss that occurs upon awakening. Bilateral hearing loss occurs in less than 2% of patients. Additionally, patients may report sensations of ear fullness or blockage, tinnitus, dizziness, nausea, and vomiting.&lt;b&gt;Aim:&lt;/b&gt; Defining the management of SSNHL in pregnant women.&lt;b&gt;Case report:&lt;/b&gt; This article describes the case of a 36-years-old pregnant woman who developed hearing impairment in the left ear in the third trimester along with tinnitus and balance disorders.&lt;b&gt;Discussion:&lt;/b&gt; The occurrence of SSNHL in pregnant women is rare and not well understood. Majority of pregnant patients with SSNHL experienced the condition in second or third trimester. Key elements facilitating an accurate diagnosis include: interview and physical examination, hearing tests, balance evaluation, and imaging studies. The exact causes of SSNHL in pregnant women remain unknown. However, hormonal changes during pregnancy can have some contribution to development of this condition. Onset of SSNHL symptoms could resemble Ménière’s disease.&lt;b&gt;Conclusions:&lt;/b&gt; Due to rare occurrence of SSNHL in pregnant women, there is no standardized approach to managing this medical issue. Given that most cases of SSNHL are classified as idiopathic, empirical treatment primarily involves steroids.

A better understanding of basic science may help our management of LUTS/LUTD in older persons with nocturnal polyuria and nocturia: ICI-RS 2024.

To discuss the role of autocrine/paracrine signaling of urothelial arginine vasopressin (AVP) on mammalian bladder capacities and micturition thresholds, impact of distension on water/urea reabsorption from the bladder, review of the literature to better characterize the central/peripheral effects of AVP, desmopressin (dAVP) toxicity, and urine biomarkers of nocturia. This review summarizes discussions during an International Consultation on Incontinence-Research Society2024 think tank with respect to the role of urothelial AVP in aged individuals with nocturnal polyuria, impact of solute and water reabsorption by the bladder on uninterrupted sleep, central effects of AVP, pharmacological basis of dAVP toxicity, and biomarkers in nocturia/lower urinary tract dysfunction(LUTD) with neurological diseases. Consensus recognized AVP function and pathways in thecentral nervous system(CNS), pre-proAVP localized using immunohistochemistry in bladder sections from adult/aged noncancerous human punch biopsies and rodent bladder sections is likely to accelerate the systemic uptake of water and urea from the bladder of anesthetized mice instilled with 3H-water and 14C-urea. Mechanisms for charged and uncharged solutes and water transport across the bladder, mechanism of dAVP toxicity, and utility of urine biomarkers in those with neurological diseases/nocturia were determined from literature reviews. Pre-proAVP is present in human/rodent bladders and may be involved in water reabsorption from bladder that prevents the sensation of fullness for uninterrupted sleep in healthy adults. The mechanism of action of AVP in the CNS was discussed, as was electrolyte/water transport across the bladder, the basis for dAVP toxicity, and feasibility of urine biomarkers to identify nocturia/LUTDwith neurological diseases.

Back on Track

This paper addresses the current nostalgia mode, from the most diverse areas of merchandising and cultural production to the very contours of today’s ‘connected’ sociality. Current nostalgia seems to impede creativity and the very idea of a future, which would appear to be unthinkable without being filtered by the the sepia lens of a cosmetic vision of the past. In TV programs, cinema, fashion or advertisement, cars or pop music, our time is the time of quotation, revival, and remake. It is a zombie time in which the future coincides with the generational time one regrets the loss of. It is a cosmetic time of hyperkinetic immobility, in which the future is a retro concept – a time that deprives subjectivity back into a full sense of its contemporaneity.

Love's realism: Iris Murdoch and the importance of being human

AbstractDefenders of two Rationality Views of love—the Qualities View and the Personhood View—have drawn on Iris Murdoch's philosophical writings to highlight a connection between love and a “realistic” perspective on the beloved. Murdoch does not inform the basic structure of these views—she is rather introduced as a supplement who shows that in love, we pay accurate, nuanced, unguarded, and unflinching attention to the other. In this paper, I contend that these authors have failed to see that Murdoch offers a distinct view of love and is inappropriate to enlist as an ally. This is in large part because they have missed the full sense of what Murdoch means by connecting love and realism. I contend that for Murdoch, to love someone means seeing them in light of a realistic vision of what it means to be human; this includes an appreciation of the limits of freedom, the formative influence of personal history, and the nature and extent of our differences from one another. This helps us to see why Murdoch variously describes loving attention as realistic, compassionate, tolerant, and extremely difficult. It also sheds light on some important and familiar ways that we criticize one another's grounds for love.

2 Cases of Intra-Labyrinthine Schwannomas With Different Treatment Options Based on Clinical Presentation

Vestibular schwannoma is a benign tumor that arises from the eighth cranial nerve and is the most common neoplasm in the internal auditory canal (IAC). It typically arises in the cerebellopontine angle or in IAC; however, in rare cases, they can arise within the labyrinth. These tumors arising in the labyrinth have been termed intra-labyrinthine schwannomas (ILS) and have different clinical features than the typical vestibular schwannomas. Clinical manifestations of an ILS typically include hearing loss, tinnitus, and vertigo, with unusual symptoms including a sense of fullness or imbalance. Temporal bone MRI is considered the most important test for diagnosing ILS. Tumors show nodular enhancement on T1-weighted images and filling defects on T2-weighted images. Treatment of ILS may include observation, microsurgical resection, and stereotactic radiosurgery depending on the location, size, and clinical presentation. In this paper, we present two cases diagnosed as ILS with different treatment options and provide a literature review for each case.

NAVIGATING THE SPECTRUM: EXPLORING DISABILITY REPRESENTATION THROUGH EL DEAFO

El Deafo, written by Cece Bell, is an illustrated visual narrative that is both visually captivating and depressed, offering readers a rare glimpse towards the experiences of the hard of being heard. The perceptive autobiographical fiction begins with a four-year-old Cece experiencing meningitis, which causes her sense of hearing to be impaired. With the help of her reliable hearing support, the Phonic Ear, Cece navigates a universe that is designed with the hearing impaired in mind. Her quest is filled with hilarity and empathy as she overcomes typical challenges. Cece gains the priceless potential to hear her professors’ instructions even when they are far away owing to the Phonic Ear, but it also causes her to feel alone and empowered. Her ostentatious technology at school makes her stand eliminated which inspires Cece to imagine herself as the superhero El Deafo. Because of her newfound strength despite various interpersonal challenges, the story can explore topics such as self-acceptance, the desire for relationships, and embracing oneself for who they are instead of just their condition. El Deafo deftly combines each of these subjects within an imaginative narrative that engages with obstacles faced when growing as an adult with a disability and appreciates victories. The use of the graphic novel format enhances the narrative by presenting Cece’s viewpoint on the world at large and her inner thoughts through creative visual components. Bell gives readers a full sense of immersion by using language bubbles to depict the complexities of communication, spanning jumbled words to misinterpreted meanings. This pioneering masterpiece praised for its faithful depiction and approachable storytelling style, is a moving relic of resiliency and creativity. El Deafo does more than just educate its viewers about the lives of deaf humanity; it resonance with everyone because of its genuine portrayal of the human desire for relationships and the path towards recognizing one’s uniqueness.

The Role of Nature Cues and Nature Relatedness in Academic Motivation and Engagement

Nature exposure in the form of immersion in natural environments can benefit students in multiple ways. Across four studies, we examined whether nature exposure in the form of visual nature cues on instructional materials might increase academic motivation and engagement among university students. Visual nature cues were presented via PowerPoint backgrounds (Study 1), online Zoom lecture backgrounds (Study 2), and on the background of calendars people used to plan for an upcoming assignment or exam (Studies 3 and 4). In each study and an internal meta-analysis, we found no evidence that nature cues increased academic engagement or motivation compared to other background images. However, participants’ self-reported nature relatedness was linked to greater academic engagement and motivation in each study and the internal meta-analysis. The interaction between nature relatedness and nature exposure was not significant. We conclude that embedding visual nature cues in educational material is not sufficiently impactful to have an effect on academic motivation and that immersion and interaction with nature in a fuller sense may be necessary to reap motivational benefits.

The deixis of literature: On the conditions for recognizing computers as authors

AbstractTaking the deictic judgment that is the modernist gesture of declaring something to be art as a starting point, this essay suggests an analogous deixis as a necessary condition for literature. This deixis also can serve as the basis for discussing the expectations of computer‐generated texts. Against the idea that computers or AI systems need only produce sufficiently good output in order to be considered authors, the essay proposes an approach that takes the social recognition of the deictic act within a community of judgment as a precondition for authorship. As an alternative to the Turing test, which is based on the paradigm of deception (people are tricked into considering computer‐written text to be written by humans), the essay favors a version of Susan Leigh Star's “Durkheim test,” which is based on the paradigm of co‐sociality (people directly recognize computers as social actors). Only if the gesture of a machine declaring something to be art is recognized as a deictic judgment in the full sense can one plausibly speak of computer authorship.

Criminal Appellate Proceedings through the Prism of a Social Project: Synergy of the Society’s Request and Legislative Regulation

Public relations, developing in the process of judicial decisions reviewing in criminal cases on appeal, arise on the basis of criminal procedure law rules with great socio-projective potential, which means activities aimed to create specific images of the future and certain details of programs and plans being developed that often result in a new or modernized social object with an original mechanism and unique means of regulation of public relations. The institution of criminal appellate proceedings has been formed in the process of a long evolution, during which many options for reviewing court decisions were tested and rejected. It also acts as an object of social design, which will help ensure the effectiveness of law enforcement and implementation of the objective of criminal proceedings, enshrined in Article 6 of the Code of Criminal Procedure of the Russian Federation. As the result of designing appeal proceedings in criminal cases, a set of scientifically grounded functional proposals can be developed. They can have a positive impact on the review in the court of appeal, since the latter should be able to satisfy the social interest (need) of interested parties, meaning not the satisfaction of the appeal, but the administration of justice in the full sense of the word.