Titanium and its alloys have evolved faster than any structural material in the history of metallurgy. The increasing employment of titanium in many different applications is mainly due to its light weight, high strength and structural efficiency. The titanium metal matrix composites (Ti-MMCs) have helped to achieve these objectives. The aim of this work is the development and study of Ti-MMCs manufactured via hot pressing at 900 °C reinforced by sub-micron and micron boron carbide (B4C), amorphous boron and sub-micron and micron titanium diboride (TiB2) particles in order to improve its mechanical properties. Full dense composites were obtained with this consolidation technique. The influence of the different reinforcements has been analyzed. Moreover, the strengthening effect of sub-micron reinforcements is compared to the effect of the material with the same chemical composition in a micro-scaled phase. Comparison has been established studying the microstructure (grain size and density) and mechanical properties through tensile and hardness tests.