Through energy and exergy analysis, the present work revisits the combustion processes generated using different fuels (CH4, C3H8, H2, LPG, Natural gas and Biogas) under the same operating conditions. First, numerical computations, in which the turbulent dynamic k-ϵ model coupled with a probability density function (PDF) approach together with different sub-models that ensure the reliability of the results, are used. Then, the First and Second Laws of thermodynamics are applied to all fuel combustion cases considered previously to predict the energy loss, exergy destruction and their corresponding efficiencies. Next, variations in the air factor, the air inlet temperature and the fuel inlet temperatures are considered to analyse the response of combustion system performance as well as energy and exergy losses for the different fuels under investigation. The results show an amelioration of combustion parameters for the mixture of fuel and air using values of λ greater than 1. Also, the preheating of the inlet air temperature has a positive effect on energetic parameters. However, preheating the inlet fuel does not take a considerable role in the efficiency amelioration and loss reduction of the combustion system. It further turns out that biogas features higher energy efficiency compared to other fuels, at approximately 89.64%, while hydrogen fuel exhibits higher exergy efficiency at around 78.70% followed by biogas with 74.96%.