FSFI Questionnaire Research Articles

Impact of endometriosis on the quality of sexual life of women of reproductive age in Poland

Aim. The aim of this study is to demonstrate the impact of endometriosis on the quality of sexual life of women in Poland, through a comparative analysis of a population of healthy women and those struggling with the condition. Methods. The study was conducted using the validated FSFI questionnaire and the author’s supplementary questions. Information about the survey was made available on social networks and groups for women with endometriosis, as well as to healthy women constituting a control group. The CAWI technique was used in the study. The survey consisted of questions divided into mod- ules: metric data, having endometriosis and previous treatment, sexuality before and after possible treatment, and for healthy women - current assessment of the quality of sexual life. Results. Endometriosis negatively affects the quality of sexual life of women of reproductive age in Poland. Decreased quality of sexual life occurring in women with endometriosis indicates the presence of clinically significant sexual dysfunctions. Dyspareunia (a type of sexual dysfunction that manifests itself as pain during intercourse (Lew-Starowicz, Lew-Starowicz, & Skrzypulec-Plinta, 2020)) is signifi- cantly more common in women with endometriosis than in healthy women in Poland. 69 percentage points more women indicate the presence of dyspareunia when suffering from endometriosis compared to healthy women. Treatment reduces pain symptoms in women suffering from endometriosis. 24 per- centage points more women show no symptoms of dyspareunia after treatment, compared to women before treatment. The presence of endometriosis does not significantly affect women’s sense of sexual at- tractiveness. Women with endometriosis, despite the presence of pain, engage in sexual activity as often as healthy women. Treatment of endometriosis, both pharmacological and surgical, increases the quality of sexual life of women of reproductive age in Poland.

Effects of gender-affirming hormone therapy on lower urinary tract symptoms and sexual function among transgender individuals.

Gender-affirming hormone therapy (GAHT) includes estrogen preparations and androgen inhibitors for transgender women, and testosterone preparations for transgender men. The aim of the study was to investigate possible effects of GAHT on lower urinary tract symptoms (LUTS) and sexual function among transgender individuals. Fifty-one transgender men and 47 transgender women were prospectively recruited. Four validated female questionnaires (Bristol Female Lower Urinary Tract Symptoms [BFLUTS] questionnaire, the Medical, Epidemiologic, and Social aspects of Aging [MESA] questionnaire, Urgency, the Severity and Impact Questionnaire [USIQ], and the Female Sexual Function Index [FSFI]) and two validated male questionnaires (International Prostate Symptom Score [IPSS], and the International Index of Erectile Function [IIEF]) were used to assess LUTS and sexual function among transgender men and women, respectively, before and during GAHT. Follow-up was performed over a period of 3-12 months. Thirty-four transgender men (mean age 24.4 ± 7.6 years) and 31 transgender women (mean age 29 ± 8.7 years) completed all questionnaires, before and during GAHT. Testosterone treatment was associated with a statistically significant improvement in sexual desire among transgender men, as reflected in the FSFI questionnaire (4.5 ± 1.2 vs. 3.6 ± 1.3, P = 0.002). None of the three LUTS questionnaires showed statistically significant changes during the treatment with testosterone preparations. Estrogen treatment was associated with a statistically significant decrease in erectile function among transgender women, as reflected by the IIEF questionnaire (9.0 ± 7.2 vs. 14.1 ± 11.1, P = 0.012). No significant changes were found in LUTS during the treatment with estrogen preparations, except for a slight worsening of nocturia (2.1 ± 1.8 vs. 1.1 ± 1.4, P = 0.009). GAHT was not found to be associated with significant LUTS in both transgender men and women. Nevertheless, some effects on sexual function were observed, mainly a decrease in erectile function among transgender women and an increase in sexual desire among transgender men.

Methods for assessing quality of life in cancer

Background. The problem of a significant reduction in the quality of life (QoL) of oncological patients remains relevant despite current achievements in medicine. The issue of standardizing methods for assessing QoL in such patients is relatively acute. Patients undergo this assessment from the diagnostic stage to the end of rehabilitation, so it’s important to choose an accurate and precise method for QoL evaluation.Objective: to analyze existing questionnaire-based methods for assessing QoL in cancer patients.Material and methods. The search for publications was conducted in the scientific databases PubMed/MEDLINE, ScienceDirect, and eLibrary. Additionally, the sources found by queries in Yandex and Google search engines by each researcher individually were considered. The review included 38 articles.Results. The vast majority of questionnaires used to assess QoL in oncological patients can be divided into two large groups: based on QLQ-C30 and FACT-G. Despite the similarity between QLQ-C30 and FACT-G questionnaires, some shift in their focus was shown. QLQ-C30 is more oriented on physical indicators, and FACT-G is more aimed at social and emotional well-being. Besides them, questionnaires that proved to identify and monitor individual groups of symptoms and syndromes were presented: FSFI, HADS and Russian questionnaire on well-being, activity, mood.Conclusion. The obtained results indicated a fairly wide choice of questionnaires for the overall assessment of QoL and its individual elements. They include both proven screening and monitoring tools and those requiring validation and expansion of the evidence base. Due to high effectiveness of questionnaires as QoL screening and monitoring tools, further work is needed to ensure that they are widely included in clinical guidelines.

(O-38) SEXUAL FUNCTION OF WOMEN WITH NORMAL WEIGHT, OVERWEIGHT AND OBESITY FROM 18 TO 50 YEARS OLD

Abstract Introduction Female sexual dysfunctions (FSD) can influence physical and mental health, causing limitations in the ability to respond to or enjoy sexual pleasure. Studies show that overweight and obesity can lead to the onset of FSD, but the evidence found remains conflicting. Objective To investigate and compare the sexual function of women between 18 and 50 years old, obese, overweight and eutrophic. Materials and methods Observational and comparative study. A link to the questionnaire was sent through social networks to women between 18 and 50 years old, sexually active in the last four weeks before answering the questionnaire, after agreeing to participate in the study and signing the consent form, they filled out a form. with demographic data and the Female Sexual Function Index questionnaire, postmenopausal women were excluded from the survey. This study was approved by the ethics and research committee of the FMABC University Center with opinion number: 4,229,411. Results 325 women participated in the study, with an average age of 28 years, where 186 were classified as obese (49.60%), 109 as overweight (29.07%) and 80 as obese (21.33%, the majority married in a stable union). . union (50.13%) or single (42.93%).In the total score of the FSFI questionnaire (median), non-obese participants obtained 16.4 points, overweight participants obtained 16.4 points, and obese participants they obtained 17.1, without significant difference. in the comparison of DSF according to BMI classification (p=0.887). Conclusions There were no statistically significant results on sexual function in obese, overweight and normal weight women in the study. Financing No conflict.

Urinary symptoms and sexual function after hysterectomy secondary to cervical cancer: A prospective, cohort study

Introduction and HypothesisThe estimated worldwide incidence of cervical cancer (CC) is half a million cases per year. Surgical treatment is the mainstay approach for this condition. ObjectivesTo assess the effects of hysterectomy due to cervical cancer in urinary symptoms and sexual function and the disorder related impact on the quality of patients life. Study DesignA cohort study was performed in Fortaleza/CE (Brazil) with 71 patients; of these, 31 were diagnosed with cervical cancer (G-CCU) and 40 with gynecological benign disease (G-PB). Sexual function (FSFI questionnaire), quality of life (SF-36 questionnaire) and urinary symptoms (KHQ instrument) were investigated in both groups at baseline (T0), one month (T1) and four months after surgery (T2). ResultsBoth groups presented at baseline, similar urinary symptoms (p > 0.05), but this frequency doubled for the G-CCU group at T1 and remained unchanged at T2 (p = 0.012). G-PB’s frequency of symptoms remained the same for 4 months after surgery. At baseline G-PB had higher risk for sexual dysfunction than G-CCU (82.5 % versus 54.8 %, p = 0.011). However for G-CCU, an increase of this percentage was perceived at T2.Women from the G-CCU group presented worse general and specific quality of life results. ConclusionWomen underwent to hysterectomy due to cervical cancer presented higher percentages of urinary symptoms, higher risk for sexual dysfunction and worse general and specific quality of life scores.

Клінічна характеристика жінок із жіночою сексуальною дисфункцією та ендометріозом

Endometriosis is a disease characterized by the presence of endometrial tissue outside the uterine cavity. Endometriosis refers to estrogen-dependent diseases, clinically manifested by dysmenorrhea, dyspareunia, dyschezia. Decreased fertility in women with endometriosis is associated with the presence of chronic inflammation that leads to pelvic pain and infertility. It is believed that endometriosis is associated with mood disorders such as anxiety or depression, which can create a pathological background for sexual dysfunction. Purpose - to establish the relationship between female sexual dysfunction (FSD) and external genital endometriosis in order to optimize women's pregravid preparation. Materials and methods. 100 women of reproductive age were examined. The main group (the Group I) consisted of 70 women who had external genital endometriosis (diagnosed by ultrasound examination of the pelvic organs, ovarian endometrioma size up to 5 cm). The main group was divided into 2 subgroups: IA - 40 women with FSD and endometriosis; IB - 30 women with FSD without endometriosis. The control group (the Group II) included 30 healthy reproductively active women in the pre-gravid stage. In the course of the study, the nosological unit approved by the World Health Organization (1999) was taken into account and taken as a basis - FSD, which include disorders of desire, arousal and reaching orgasm, dyspareunia and vaginismus. The results of clinical and biochemical studies were processed using a specialized package of statistical programs Statistica 8.0 (StatSoft Inc., USA). The following criteria were used for statistical processing of the obtained data: Kruskal-Wallis test, Mann-Whitney U test, Pearson chi-squared (χ2) test, Wilcoxon test. Results. The analysis of the definition of FSD in women with endometriosis clearly indicates the presence of signs of FSD in all areas and is statistically significantly different from the indicator of healthy women. Conclusions. There is a relationship between endometriosis and FSD that can be determined using the FSFI Questionnaire Calculator. Since FSD and endometriosis have a polymorbid background, treatment should be carried out by a multidisciplinary team of doctors and be personalized. The research was carried out in accordance with the principles of the Helsinki Declaration. The study protocol was approved by the Local Ethics Committee of the participating institution. The informed consent of the patient was obtained for conducting the studies. No conflict of interests was declared by the author.

A comprehensive interventional program to improve the sexual function of women with endometriosis: a mixed-methods protocol study

BackgroundEndometriosis is a chronic disease affecting 6–10% of women worldwide. Sexual dysfunction has been reported in a significant percentage of these patients. Thus, the present study will be conducted to design, implement, and determine the effectiveness of an interventional program to improve the sexual function of women with endometriosis.Materials and methodsThis mixed-methods study will be carried out in three phases with a sequential exploratory approach. In the first phase (qualitative study) participants will be selected by purposive sampling in Isfahan, Iran. The data will be collected through in-depth interviews and field notes and analyzed using conventional content analysis. The interventional program will be designed in the second phase based on the results of the qualitative study and literature review and using the Delphi method and panel of experts. The interventional program will be implemented at the individual level in the third phase to investigate its effect on improving women’s sexual function. This phase includes quasi-experimental research, in which the pre- and post-intervention data will be collected from the intervention and control groups using the FSFI questionnaire and analyzed by descriptive and inferential statistical methods. Ultimately, a suitable interventional program will be presented by combining the data obtained in the qualitative and quantitative phases of the research.ConclusionConducting the present study, along with the design and implementation of an appropriate, native, and culturally sensitive interventional program, can contribute to improving the sexual function of women with endometriosis and enhancing the quality of sexual relations between couples.

Research on sexual functioning of women based on the fsfi questionnaire and bmi

Research on sexual functioning of women based on the fsfi questionnaire and bmi

The effect of kegels exercises on sexual function in elderly in the east Jakarta region

Introduction: Elderly people experience a decline in the function of their reproductive organs, which will affect intimate relationships with their partners, thus having an impact on physiological problems regarding sexual needs, so they are expected to be able to adapt to changes by improving their sexual function by doing Kegel exercises. Objectives: to determine the effect of Kegels exercises on sexual function in the elderly in the East Jakarta area. Methods: The research uses a quasi-experimental design with a pre-post test design without a control group, namely observations carried out before treatment and after treatment without using a control group, with a total of 27 respondents starting from May to August 2023 using the 19-item FSFI questionnaire. Results: The results showed that sexual scores increased by an average of 2 after Kegel exercises were carried out: sexual desire was 2, sexual arousal was 2.63, lubrication was 1.37, organism was 1, sexual satisfaction was 1.70, pain decreased by 1.19, p value = 0.000, and FSI score ≤ 26.55 for 21 people (77.8%) who did not experience sexual dysfunction. Conclusion: Sexual function will increase if you do light exercise such as gymnastics, namely Kegels exercises. This can also reduce sexual dysfunction.

Impact of the covid-19 pandemic on mental health and sexuality of female doctors.

COVID-19 pandemic has changed people's lives around the world due to restrictive measures adopted by governments. The impact of this change on female sexuality needs to be further investigated, particularly between female doctors who are more at risk as they are directly involved with health care services. An online survey has been filled out by female doctors. The questionnaire evaluates sexual function, depression, anxiety, burnout, sociodemographic and professional data, and it was answered during the peak of COVID-19 pandemic in Brazil. The main outcome is female doctors' sexual function during COVID-19 pandemic, which was evaluated by analyzing FSFI questionnaires. The secondary outcome is related to their mental health, assessed via depression, anxiety and burnout questionnaires. A sample of 388 female doctors filled out the questionnaire. The median age was 34.0 (29.0, 43.0) years old. The total FSFI median score was 23.8 [18.9, 26.8] with desire domain median of 5.0 [3.0, 7.0]. In our sample, 231 (59.5%) women had depression and/or anxiety, out of these, 191 (82.7%) had depression and 192 (83.2%), anxiety. From these samples of doctors with depression and/or anxiety, 183 (79.2%) had sexual dysfunction. This finding suggests that doctors are experiencing a high risk of sexual dysfunction and mental illness during the COVID-19 outbreak. A high index of depression and/or anxiety was shown in the studied population, with almost 80% of them reaching criteria for sexual dysfunction. Working in the frontline is related to worse mental health conditions. Depression and anxiety were found as potential mediators of burnout effect on sexual function.

(055) Effect of Loop Electrosurgical Excision Procedure (LEEP) on Female Sexual Function

Abstract Introduction Cancer of the uterine cervix is the third most common gynecologic cancer and accounts for approximately 528,000 new cancer cancers globally, on an annual basis. Cervical cancer continues to be the second leading cause of cancer death for women aged 20 to 39. Human papillomavirus (HPV) infection is responsible for the majority of cervical cancer cases. Screening with cervical cell cytology in conjunction with HPV testing is an effective screening technique that enables providers to risk-stratify women with cervical dysplasia for subsequent development of invasive cervical cancer. Colposcopy is a diagnostic technique utilized as a follow-up for abnormal cervical screening test results. Depending on the adequacy of the colposcopy procedure and the patient’s histology, an excisional procedure may be required. Loop electrosurgical excision (LEEP) is one of three common techniques employed to remove the pre- cancerous transformation zone. Theoretically this “minimally invasive” approach reduces thermal injury to surrounding structures, causes less intraoperative bleeding, and creates smaller excised specimens. The aim of this technique is to minimize cervical trauma compared to other excisional techniques. However, to date, there have been no prospective studies to examine the effect of excisional biopsy on patient-centered outcomes, such as sexual satisfaction post-procedure and subsequent development of subsequent sexual dysfunction. A 2015 review article found only 6 studies examining the effect of excisional biopsy on sexual dysfunction. There have only been four published prospective studies examining the effect of LEEP on sexual function, and only two of them utilized validated research questionnaires. Our university-based clinic performs approximately 1000 colposcopies and 100 LEEP procedures annually. The Medical Faculty Associates practice providers care to both a racially and socioeconomically diverse patient population. Objectives We plan to conduct a prospective cohort study in 736 women comparing FSFI and FSDS-R scores, and the prevalence of sexual dysfunction (defined as FSFI < 26 points) among patients who undergo colposcopy versus patients who undergo both colposcopy and LEEP. Methods The FSFI and FSDS-R questionnaires will be completed at their initial encounter after having an abnormal pap smear. This initial questionnaire will serve as our baseline measurement. If the patient did not need any additional procedures, they will complete the FSFI and FSDS-R questionnaires at 6 and 12 weeks after colposcopy. If further excision is required, patients will complete the questionnaires at 6 and at 12 weeks after their LEEP procedure. Results Results are pending completion of study enrollment. Analyses will be controlled for parity, age, menopausal status, psychotropic medication use, anxiety or depression diagnosis. Conclusions We anticipate our study to find no difference in FSFI score or FSDS-R score among women who have undergone colposcopy versus colposcopy versus LEEP. We plan to have interim results to present at the upcoming conference. Disclosure No.

Photobiomodulation et troubles vulvovaginaux après traitements anticancéreux

Anticancer treatments induce vulvovaginal complications that alter the quality of life and sexuality of patients. New technologies, such as photobiomodulation, could address this problem, for which few effective therapeutic solutions exist. The objective of this study was to describe the characteristics of patients seeking treatment and to observe the effects of photobiomodulation. This is a prospective cohort of patients treated for cancer, in failure of first-line medical treatment, managed at the University Hospital of Nîmes. The history, symptoms and impact of the disorders on their quality of life were collected. At follow-up, improvement was assessed using the PGI-I and FSFI questionnaires. Twenty-eight patients were treated. They were all menopausal, half of them after anticancer treatments [chemotherapy (78%), radiotherapy (36%), hormone therapy (36%)]. The main symptom reported was vaginal dryness (72%). Seventy-one percent of patients (n=20) felt that their daily life was affected≥8/10. All patients had sexual dysfunction. Twenty-two patients received at least 6 sessions of photobiomodulation. Seventy-two percent (n=18) of patients felt better or much better after treatment (PGI-I≤2). The median improvement estimated by the patients was 65% (Q1=50%; Q3=72.5%). There was also a significant clinical improvement. No serious adverse events were reported. Due to the small number of patients in a heterogeneous population with no control group, we cannot extrapolate our results. However, the objective was to assess the status of these pathologies and the contribution of photobiomodulation in patients who have failed first-line treatment; and these results are encouraging.

Efficacy of Fractional CO2 Laser Treatment for Genitourinary Syndrome of Menopause in Short-Term Evaluation-Preliminary Study.

The postmenopausal state covers 40% of modern women's lives and 50-70% of postmenopausal women report GSM symptoms such as vaginal dryness, itching, frequent inflammations, lack of elasticity, or dyspareunia. Consequently, a safe and effective method of treatment is crucial. In a group of 125 patients, a prospective observational study was performed. The aim was to evaluate the clinical effectiveness of fractional CO2 laser in the treatment of GSM symptoms using a protocol of three procedures in 6-week intervals. The vaginal pH, VHIS, VMI, FSFI, and treatment satisfaction questionnaire were used. The fractional CO2 laser treatment was effective in improving all the objective forms of evaluation: vaginal pH (from 5.61 ± 0.50 at the baseline up to 4.69 ± 0.21 in the 6-week follow-up after the third procedure); VHIS (12.02 ± 1.89 at the baseline vs. 21.50 ± 1.76); VMI (21.5 ± 5.66 vs. 48.4 ± 4.46). Similar results were obtained for FSFI: 12.79 ± 5.351 vs. 24.39 ± 2.733, where 79.77% of patients were highly satisfied. Fractional CO2 laser therapy increases the quality of life by having a beneficial effect on the sexual function of women with GSM symptoms. This effect is obtained by restoring the correct structure and proportions of the cellular composition of the vaginal epithelium. This positive effect was confirmed by both objective and subjective forms of evaluating GSM symptom severity.

Quality of life, voiding & sexual dysfunction following robot-assisted vesicovaginal fistula repair: a tertiary care centre experience.

Robot-assisted VVF (RA-VVF) repair has the advantage of small cystotomy, precise dissection and minimal surrounding tissue trauma. Translation of this to better functional outcomes is not studied so far. This study aims to evaluate the quality of life, voiding, and sexual dysfunction following robot-assisted VVF repair. Women with successful RA-VVF repair were screened using UDI-6, IIQ-7, FSFI, and WHOQOL-BREF questionnaires. The preoperative assessment was done in the prospective cohort only. Of the 75 women who underwent RA-VVF repair, 47 were enrolled, 33 in retrospective, and 14 in a prospective cohort. Overall, 28 (60%) women had urinary complaints with a median UDI-6 total score of 4 (0-100) and IIQ-7 score(0-23) in 5 (10%) women. However, UDS (15 women) showed no DO with cystometric capacity (352 ± 98.12) ml and normal compliance in 14 (93%) women. Mean BOOI and DCI were 11.90 ± 7.01 and 44.25 ± 8.60 respectively, with PdetQmax ranging from 17 to 44. None had difficulty in voiding (Qmax 13.85 ± 4.90). Twenty (43%) women were sexually active, and 2 had sexual dysfunction (FSFI score < 26.55). Quality of life was "good" to "very good" in all domains (score > 90) except for the social domain. The prospective cohort showed significant improvement in UDI-6 score (p < 0.05), IIQ-7 score (p < 0.05), and quality of life (p < 0.05) postoperatively. RA-VVF repair results in minimal voiding dysfunction and significant improvement in overall quality of life. For sexual dysfunction assessment, a longer follow-up is required.

PD42-06 EFFECTS OF INTRAVESICAL BOTULINUM TOXIN TYPE-A INJECTION LOCATION ON SYMPTOM SCORES AND SEXUAL FUNCTIONS IN FEMALE PATIENTS WITH A DIAGNOSIS OF REFRACTORY BLADDER PAIN SYNDROME/INTERSTITIAL CYSTITIS: A RANDOMIZED, PROSPECTIVE STUDY

You have accessJournal of UrologyCME1 Apr 2023PD42-06 EFFECTS OF INTRAVESICAL BOTULINUM TOXIN TYPE-A INJECTION LOCATION ON SYMPTOM SCORES AND SEXUAL FUNCTIONS IN FEMALE PATIENTS WITH A DIAGNOSIS OF REFRACTORY BLADDER PAIN SYNDROME/INTERSTITIAL CYSTITIS: A RANDOMIZED, PROSPECTIVE STUDY Murat Karaburun, Eralp Kubilay, Derya Gökmen, Mehmet İlker Gökçe, Evren Süer, and Ömer Gülpınar Murat KaraburunMurat Karaburun More articles by this author , Eralp KubilayEralp Kubilay More articles by this author , Derya GökmenDerya Gökmen More articles by this author , Mehmet İlker GökçeMehmet İlker Gökçe More articles by this author , Evren SüerEvren Süer More articles by this author , and Ömer GülpınarÖmer Gülpınar More articles by this author View All Author Informationhttps://doi.org/10.1097/JU.0000000000003352.06AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: To determine the effect of Intravesical Botulinum Toxin type-A (BTX-A) treatment with trigon included and trigone sparing on symptoms and sexual function in female patients diagnosed with Bladder Pain Syndrome/Interstitial Cystitis (BPS/IC) who did not benefit from conventional treatments. METHODS: Patients with BPS/IC who were treated with hydrodistension+BTX-A were enrolled in the study between January 2020 and April 2022. Using the stratified randomization technique, patients were randomly randomized to one of two groups: hydrodistension+trigone sparing injection (Group-1) or hydrodistension+trigone-included injection (Group-2). The study comprised a total of 27 patients. The patients were evaluated with VAS, ICSI, ICPI, FSFI questionnaires, and 3-day voiding diaries, voiding tests, and residual urine tests (uroflowmetry and residue determination) in the preoperative period and in the postoperative first and third months. RESULTS: The study comprised a total of 27 patients, 14 from Group-1 with a mean age of 40,9 (±9,25) and 13 from Group-2 with a mean age of 41.7 (±10.3). Preoperative VAS, ICSI, ICPI, and FSFI scores for 27 patients were 8.95±1.39; 16.21±2.94; 14.38±2.27 and 15.92±3.73, respectively. VAS, ICSI, ICPI, and FSFI scores were 3.47±2.94; 7.14±3.97; 6.47±3.95 and 22.41±5.02 at the first postoperative month, respectively. It was 2.69±3.18; 5.79±5.08; 5.79±4.95 and 24.41±6.06 in the third month postoperatively. Treatment led to statistically significant improvements in all four variables (p<0.001). While significant improvement was observed with treatment in both groups, no difference was found between the two groups in terms of treatment results (p: 0.89; p: 0.341; p: 0.488 and p: 0.706, respectively). In total, two patients had urinary tract infection in the postoperative period and one patient had retention, but there was no difference between the two groups in terms of adverse effects (p>0.05). CONCLUSIONS: Intravesical BTX-A treatment is an effective and safe treatment in female patients with BPS/IC unresponsive to conventional treatments. The treatment also contributes positively to sexual functions. The inclusion of trigone in the injections makes no difference to the treatment response. Source of Funding: none © 2023 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 209Issue Supplement 4April 2023Page: e1113 Advertisement Copyright & Permissions© 2023 by American Urological Association Education and Research, Inc.MetricsAuthor Information Murat Karaburun More articles by this author Eralp Kubilay More articles by this author Derya Gökmen More articles by this author Mehmet İlker Gökçe More articles by this author Evren Süer More articles by this author Ömer Gülpınar More articles by this author Expand All Advertisement PDF downloadLoading ...

MP45-17 THE NEW COUPLE DYNAMICS AT THE TIME OF COVID-19: HOW THE SEXUAL HEALTH OF MALE AND FEMALE INDIVIDUALS HAS CHANGED DURING THE PANDEMIC

You have accessJournal of UrologyCME1 Apr 2023MP45-17 THE NEW COUPLE DYNAMICS AT THE TIME OF COVID-19: HOW THE SEXUAL HEALTH OF MALE AND FEMALE INDIVIDUALS HAS CHANGED DURING THE PANDEMIC Piero Mannone, Davide Baiamonte, Gabriele Tulone, Gianpaolo Di Gregorio, Nicola Pavan, Rosa Giaimo, and Alchiede Simonato Piero MannonePiero Mannone More articles by this author , Davide BaiamonteDavide Baiamonte More articles by this author , Gabriele TuloneGabriele Tulone More articles by this author , Gianpaolo Di GregorioGianpaolo Di Gregorio More articles by this author , Nicola PavanNicola Pavan More articles by this author , Rosa GiaimoRosa Giaimo More articles by this author , and Alchiede SimonatoAlchiede Simonato More articles by this author View All Author Informationhttps://doi.org/10.1097/JU.0000000000003291.17AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: The current pandemic has forced the population to experiencing negative psychological reactions and changes in sexual behavior. The aim of our study is to investigate how the sexual health of male and female individuals has changed during the COVID pandemic period. METHODS: We conducted a retrospective cohort study with an anonymous survey using the Google Forms platform on a population of individuals of both sexes. Participants were spontaneously enrolled and asked to answer questions regarding their sexual health and habits during the pre-pandemic (T0) and a pandemic (T1) period. Participants were stratified into four age groups: G1 (18-35 yo), G2 (36-50 yo), G3 (51-60 yo), and G4 (61-70 yo). Male and female patients’ sexual function was evaluated with IIEF-15 questionnaire and FSFI questionnaire, respectively; both populations responded to the CSFQ-14 questionnaire. Data were compared between groups reporting the mean standard deviation (SD). Results were compared with the analysis of variance (ANOVA) and the mean scores of the questionnaires were analyzed with the Wilcoxon test. RESULTS: 244 patients, 144 males and 100 females spontaneously participate to the survey. Overall, IIEF-15 score in the general population at T1 were lower than T0 (58.95±15.8 vs 62.44±11.1, p<0.001). However, considering results divided by age groups, there was a statistically significative difference only in the younger age group (G1: 58.22±16.9 vs 63.41±9.7, p<0.0001). Regarding the female subjects, the statistical analysis showed that the differences between T0 and T1 were not statistically significative both for the total population (p=0.9) and for the different age groups. Analyzing the single items of FSFI, Q15 (mean 2.77±1.6 vs 2.46±1.5, p<0.005) and Q16 (mean 2.87±1.5 vs 2.46±2.4, p<0.0001) that are part of the Satisfaction domain, demonstrated a significative differences between groups. In both gender groups there was no differences in CSFQ-14 at T0 and T1. CONCLUSIONS: During the pandemic period, the male population in our study reported an impairment in the sexual function. However, in female individuals there were no variations in the two periods analyzed. The COVID-19 pandemic has played a role in changing couple dynamics and more research will be necessary to study the effects on the sexual health of the affected population. Source of Funding: None © 2023 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 209Issue Supplement 4April 2023Page: e628 Advertisement Copyright & Permissions© 2023 by American Urological Association Education and Research, Inc.MetricsAuthor Information Piero Mannone More articles by this author Davide Baiamonte More articles by this author Gabriele Tulone More articles by this author Gianpaolo Di Gregorio More articles by this author Nicola Pavan More articles by this author Rosa Giaimo More articles by this author Alchiede Simonato More articles by this author Expand All Advertisement PDF downloadLoading ...

Factors associated with sexual disorders in women followed for breast cancer

IntroductionBreast cancer is the most frequently encountered malignant tumor among women in Tunisia and in the world. The quality of sexual life of patients with breast cancer is impaired by multifactorial mechanisms.ObjectivesThe aim of our study was to determine the factors associated with sexual disorders in patients followed for breast cancer.MethodsCross-sectional analytic study including patients followed for breast cancer at the outpatient medical oncology consultation of Hadj Ali Soua regional hospital from January to March 2021. We collected sociodemographic and clinical data with an assessment of sexuality (FSFI), marital satisfaction (MAT), psychological profile (HAD) and quality of life (SF36).ResultsFifteen patients were included with a mean age of 49.87 ± 8.48 years and a mean age at diagnosis of 46.73 ± 7.55 years. At the TNM classification, 66.6% of the patients had a T1 or T2 at the time of diagnosis and 80% had an N0. All patients received a surgical intervention, which was conservative in 53.3% of cases. No patient underwent breast reconstruction. Chemotherapy and hormone therapy were prescribed in 86.7% of patients. The mean score of the FSFI questionnaire in our study was 17.25. Eleven patients (73.3%) had an FSFI score below 26.55. We found negative correlations between age and FSFI score (r=-0.622; p=0.013). We noted statistically significant negative correlations between FSFI and HAD-D (r=-0.606; p=0.017) and FSFI and HAD-a (r=-0.707; p=0.01) as well as significant correlations between FSFI and the following items: RE (r=0.84p=0.000), SF (r=0.684 p=0.005), GH (r=0.671 p=0.006) and MCS (r=0.788 p=0.000).ConclusionsFocusing on a small sample of patients followed for breast cancer, our study provides an assessment of the sexual function in its various areas and shows how sexuality is deeply intertwined with other sections of medical management.Disclosure of InterestNone Declared

Effects of HPV Positivity in Women on Couples Sexual Behavior

We aimed to analyze the effect of HPV positivity in women, on women’s psychology, sexual health, and male sexuality. Participants in the study were sexually active patients with high-risk HPV positivity and without any cancerous and precancerous lesions in the pathological examination. Participants and their partners’ sexual health were evaluated with the FSFI questionnaire and the International Index of Erectile Function (IIEF) Score. The Beck anxiety inventory (BAI) form was used to determine participants’ anxiety status. The presence of premature ejaculation was analyzed using the premature ejaculation diagnosis tool (PEDT) form. Comparison of FSFI scores at the time of diagnosis and one month later revealed a significant decrease (18.1 vs 15.1, p = 0.001). Partners’ IEFF score decreased from 27.7 at diagnosis to 25.5(p = 0.001). The mean BAI score rose from 13.9 at diagnosis to 25.5 one month later (p = 0.001). Participants’ partners had a significantly worse PEDT score one month after diagnosis (6.0 vs 10.8, p = 0.001). The present study demonstrated a significant deterioration in female psychological and sexual health caused by HPV positivity. Moreover, after their partner’s diagnosis with HPV positivity, men were significantly more likely to suffer from erectile dysfunction and premature ejaculation.

Development and psychometric properties of the human papillomavirus-quality of life (HPV-QoL) questionnaire to assess the impact of HPV on women health-related-quality-of-life

PurposeThe HPV-Quality-of-Life (HPV-QoL) questionnaire was developed to determine the impact of Human-Papillomavirus (HPV) infection and related interventions on women health-related quality-of-life. This study provides the development and preliminary psychometric properties of a novel HPV-QoL questionnaire for adult women with HPV.MethodsAfter reviewing literature and cognitive debriefing interviews in women who had experienced HPV-related conditions, instrument items and domains were developed. A draft questionnaire was pilot tested for comprehension and ease of completion. Psychometric evaluation of the final HPV-QoL scale was conducted in a psychometric study including 252 adult women derived to our centre by a positive HPV test in the cervical cancer screening program and/or presenting genital warts.ResultsThe present study reveals that the HPV-QoL questionnaire, structured in four domains: general well-being [including psychological well-being and social well-being subdomains], health, contagiousness and sexuality, showed good metric properties of feasibility irrespective of age or educational level, and time to administer was less than 5 min. Internal consistency and temporal stability (reliability) showed values above the acceptable standards. The instrument showed its concurrent validity by means of a significant correlation with mental and sexual existing instruments; GHQ-12 and FSFI questionnaires, respectively, and also known groups validity showing significant differences among the subgroups regarding either sexual dysfunction or mental deterioration.ConclusionThis study provides an HPV-QoL questionnaire with an innovative patient-reported outcomes specific measurement tool to assess HRQoL in women with HPV infection. The present study suggests this questionnaire has satisfactory psychometric properties, including validity and reliability. Results support the use of the HPV-QoL questionnaire as a HRQoL measurement instrument for daily medical practice and clinical research.

Sexual function and associated factors at 24 months postpartum: a cohort study / Função sexual e fatores associados aos 24 meses de pós-parto: um estudo de coorte

The aim of this study was primarily to investigate the rates of indicative sexual dysfunction (SD) in the last gestational month and at 24 months postpartum. As a secondary objective, we sought to identify the main factors associated with SD at 24 months. The study sample included 131 women who gave birth in maternity wards at two public hospitals in southern Brazil between the period of October 2018 and April 2019. In the first stage (T1), an interview was carried out while the participants were hospitalized, during the immediate postpartum period, based on a clinical record and on the female sexual function questionnaire (Female Sexual Function Index – FSFI). In the second stage (T2), assessments were made via telephone, given the restrictions of the Covid-19 pandemic, 24 months after the initial data collection. At this stage, an updated clinical record was used, followed by the FSFI questionnaire. The final sample consisted of 82 women. Data analysis was performed using descriptive statistics. Data normality was verified using the Kolmogorov-Smirnov test. The chi-square test was used to compare categorical variables in two stages. The Wilcoxon test was used to compare the FSFI score and its domains, both in the last gestational month and at 24 months postpartum. To analyze the correlation of factors associated with the FSFI score, Spearman's test was used. As for sexual function (SF), of the women who were sexually active in the last four weeks of pregnancy (n=33), 39.4% (n=13) indicated SD, while at 24 months postpartum, the percentage was reduced to 20.7% (n=17). There was no statistically significant difference between the total FSFI scores for the two periods observed; however, the analysis of the FSFI domains showed a significant improvement in sexual desire (p=0.01) and a reduction in pain during intercourse (p=0.04) at the 24-month postpartum follow-up. Thus, indications of SD, both in the last month of pregnancy and at 24 months postpartum, can be considered moderate. Furthermore, it was possible to identify factors associated positively, as well as negatively, with SF at 24 months postpartum.