The unloading issue is prevalent in underground engineering and significantly affects construction safety and the operation of surrounding facilities, while research regarding it is still relatively scarce. A novel CFD-DEM coupling method with dynamic fluid meshes is proposed to reproduce the unloading effect and reveal its micro-scale mechanisms. It adopts uniformly distributed point sets to generate/update fluid meshes and solves with a proposed numerical mapping method. The one-dimensional linear unloading modeling method is further established. The numerically obtained excess pore pressure and rebound deformation under the one-way drained condition are compared with the analytical solutions. The coupling method demonstrates considerable reliability in forecasting the pore pressure response and its advantage for predicting rebound deformation is revealed. The evolutions of the fluid velocity field, particle displacement field, and pore pressure distribution profile are described. The influences of fluid compressibility, unloading rate, unloading volume and initial pore pressure on the unloading characteristics are carefully investigated. The results indicate that the pore pressure is obviously influenced by the selected factors. However, the impact of unloading volume on the final rebound deformation is most significant. Finally, influences of frictionless walls, two-way drained conditions, buoyancy and fluid viscosity on the unloading response are further discussed.