Free Delivery Research Articles

Delivery of BikDD proapoptotic gene in Peptide-18-targeted Poly(2-oxazoline)-DOPE nanoliposomes for breast cancer models.

Breast cancer is one of the most common cancers and a significant cause of death in females worldwide. For effective breast cancer treatment, using systems with a promising delivery of anticancer agents is an important strategy. Peptide 18 (P18), a tumor-homing peptide, shows a high binding affinity toward breast cancer cells. Nanoliposomes are known to have enhanced accumulation ability in tumors with longer systemic circulation. In this study, Poly (2-ethyl-2-oxazoline) (PEtOx) polymers conjugated with DOPE are used to prepare PEtOx-DOPE nanoliposomes. BikDD, a mutant form of the Bik gene and a member of the BH3-only proapoptotic genes, mimics the constitutively phosphorylated form of the gene. To the best of our knowledge, this study presents a novel approach by investigating P18-conjugated PEtOx-DOPE nanoliposomes (P18-PEtOx-DOPE) for the targeted delivery of BikDD to the AU565 breast cancer model. A site-directed mutated BikDD was loaded into P18-PEtOx-DOPE nanoliposomes, and the targeted drug delivery system was assessed in in vitro and in vivo breast cancer models for efficiency, safety, and efficacy. The increased Bik mRNA expression levels in AU565 cells suggest a high effectiveness of the targeting PEtOx-DOPE nanoliposomes. Following the in vitro studies, the delivery of BikDD by P18-PEtOx-DOPE nanoliposomes was analyzed in CD-1 nude mice models. The animal study showed no significant difference in the tumor volume of the CD-1 nude mice treated with P18-PEtOx-DOPE-BikDD nanoliposomes compared to the free delivery of BikDD. Our preclinical studies suggest that P18-PEtOx-DOPE-BikDD nanoliposomes may be promising gene carriers for targeted breast cancer therapy. Thus, further studies should be carried out to determine the prolonged use of this drug delivery system in breast cancer therapy.

Post-Purchase Trip Heterogeneity: Exploring the Impact of Free and Paid Return Deliveries on Shopping and Transport Mode Choices in the USA

This paper explores aspects of the post-purchase trips generated by the necessity to return purchased clothing to the shops. Particular focus is given to online shopping that has become common for clothing purchases. This study’s novelty lies in delving into the underlying reasons behind post-purchase trips, particularly those initiated when customers seek to return clothing to retailers. It examines the impact of free and paid return delivery options as key factors driving consumers’ decisions in relation to clothing returns. The study consists of two branches and leverages the random utility maximization theory. The first branch focuses on the impact of free and paid return options on the preferred shopping channels by utilizing a stated preference dataset collected from 507 US online shoppers. The second branch of this study employs the revealed preference dataset and aims to explore the return trip behavior. The willingness-to-pay values estimated for the free return delivery option are higher among female online shoppers compared with males—$7.42 and $6.65 per delivery, respectively. It was found that among the identified “returners,” 84.62% of males and 79.91% of females showed a strong reliance on private cars for their return trips. The potential environmental consequences of return trips were evaluated, focusing on the case of the USA. Additionally, the estimated marginal probability effect revealed that factors such as an aging population, car ownership, and number of children in households positively influence car usage for post-purchase trips. The study’s implications for stakeholders are discussed.

HiViPore: a highly viable in-flow compression for a one-step cell mechanoporation in microfluidics to induce a free delivery of nano- macro-cargoes

BackgroundAmong mechanoporation techniques for intracellular delivery, microfluidic approaches succeed in high delivery efficiency and throughput. However, especially the entry of large cargoes (e.g. DNA origami, mRNAs, organic/inorganic nanoparticles) is currently impaired since it requires large cell membrane pores with the need to apply multi-step processes and high forces, dramatically reducing cell viability.ResultsHere, HiViPore presents as a microfluidic viscoelastic contactless compression for one-step cell mechanoporation to produce large pores while preserving high cell viability. Inducing an increase of curvature at the equatorial region of cells, formation of a pore with a size of ~ 1 μm is obtained. The poration is coupled to an increase of membrane tension, measured as a raised fluorescence lifetime of 12% of a planarizable push-pull fluorescent probe (Flipper-TR) labelling the cell plasma membrane. Importantly, the local disruptions of cell membrane are transient and non-invasive, with a complete recovery of cell integrity and functions in ~ 10 min. As result, HiViPore guarantees cell viability as high as ~ 90%. In such conditions, an endocytic-free diffusion of large nanoparticles is obtained with typical size up to 500 nm and with a delivery efficiency up to 12 times higher than not-treated cells.ConclusionsThe proposed one-step contactless mechanoporation results in an efficient and safe approach for advancing intracellular delivery strategies. In detail, HiViPore solves the issues of low cell viability when multiple steps of poration are required to obtain large pores across the cell plasma membrane. Moreover, the compression uses a versatile, low-cost, biocompatible viscoelastic fluid, thus also optimizing the operational costs. With HiViPore, we aim to propose an easy-to-use microfluidic device to a wide range of users, involved in biomedical research, imaging techniques and nanotechnology for intracellular delivery applications in cell engineering.

Does living in major towns favor institutional delivery in Somalia?

In developing countries, institutional delivery is a key proven intervention that reduces maternal mortality and can reduce maternal deaths by approximately 16%-33%. In Somalia, only 32% of births are delivered in a health facility with the assistance of a skilled healthcare provider. We aimed to investigate the factors hindering women from giving birth at healthcare facilities in major towns in Somalia, where most of the health facilities in the country are concentrated. A community-based health survey was carried out in 11 major towns in Somalia between October and December 2021. A structured and pretested questionnaire was used to collect data from 430 women who gave birth in the last five years. Women were recruited through convenient sampling. Descriptive statistics were used to summarize the data, and binary and multivariable logistic regression analysis was performed. Adjusted odds ratios (AOR) with 95% CI were estimated to assess the associations. The overall prevalence of institutional delivery was 57%. Approximately 38% of women living in Mogadishu and 53% living in another ten towns give birth at home. Women who had poor knowledge of the importance of health facility delivery had nearly four times higher odds of delivering at home (AOR 3.64 CI: 1.49-8.93). Similarly, those who did not receive antenatal care (AOR 2.5, CI: 1.02-6.39) and those who did not receive a consultation on the place of delivery (AOR 2.15, CI: 1.17-3.94) were more likely to give birth at home. The reasons for home delivery included financial reasons, the long distance to the health facility, and the fact that it was easier to give birth at home. The study found that home delivery is high in major towns in Somalia and is associated with a lack of understanding of the importance of health facility delivery, not using ANC, and not receiving consultancy about where to give birth. Primary health care should strengthen information, education, and communication activities. Since the health care system in Somalia is overwhelmingly private, the government may consider access to free and within-reach ANC and health facility delivery for women and girls from families who cannot pay the ANC and childbirth delivery cost.

A carrier free delivery system of a MAGL inhibitor is effective on ovarian cancer

Monoacylglycerol lipase (MAGL) is a promising target for cancer therapy due to its involvement in lipid metabolism and its impact on cancer hallmarks like cell proliferation, migration, and tumor progression. A potent reversible MAGL inhibitor, MAGL23, has been recently developed by our group, demonstrating promising anticancer activities. To enhance its pharmacological properties, a nanoformulation using nanocrystals coated with albumin was prepared (MAGL23AF). In a previous work, the formulated inhibitor showed potency in ovarian and colon cancer cell lines in terms of IC50, and was tested on mice in order to assess its biocompatibility, organs biodistribution and toxicity. In the present work, we expanded the investigation to assess the potential in vivo application of MAGL23AF. Stability assays in serum and in human derived microsomes showed a good structural stability in physiological conditions of MAGL23AF. The antitumor efficacy tested on mice bearing ovarian cancer tumor xenografts demonstrated that MAGL23AF is more potent than the non-formulated drug, leading to necrosis-driven cancer cell death. In vivo studies revealed that albumin-complexed nanocrystals improved the therapeutic window of MAGL23, exhibiting a favorable biodistribution with slightly increased accumulation in the tumor. In conclusion, the MAGL23AF showed increased in vitro stability in conditions mirroring the bloodstream environment and hepatic metabolism coupled with an optimal antitumor efficacy in vivo. These results not only validates the efficacy of our formulation but also positions it as a promising strategy for addressing challenges related to the solubility of drugs in body fluids.

Continuous increasing consumer service for multi-item dual-channel retail management

Along with the advancement of technology and consumer expectations, online-to-offline retailing is seeking attention in the retailing industries. Online-to-offline retailing is a powerful strategy that bridges the gap between the convenience and reach of online shopping with the tangible experience and service of physical stores. Customer satisfaction and brand loyalty are basic pillars to enhance profit for the retail industry. Providing different services like repairs, exchanges, and home delivery enhances customer satisfaction and builds trust in the particular industry. In e-commerce, the importance of delivery service is emphasized, with fast and reliable delivery being a key factor in customer satisfaction. An online-to-offline retailing system for multiple items is developed in this study by considering consumer service efficiency demand. A pricing strategy that relies on the channel of distribution and the impact of advertising on consumer demand is taken into account. The manufacturer offers complimentary home delivery services for orders surpassing a specified threshold. To implement advanced technologies, a huge budget is required. To make the study realistic, a budget and space are considered. The retailing system's total profit is ultimately maximized by determining the optimal values for selling price, advertisement investment, customer care costs across various channels, ordering quantity, and investment to minimize setup costs for different items. A classical optimization approach is employed to derive a semi closed-form solution for the proposed model. Sensitivity analysis and examination of special cases are provided to demonstrate the practicality of this research. Through numerical illustrations, it is established that the profit maximization occurs when the defective rate adheres to a Chi-square distribution. Imposing budget and space restrictions leads to a 19.91% increase in system profit while offering free home delivery services boosts the profit by 15.77%.

Free Radicals in Little Cigar Mainstream Smoke and the Potential Influence of Flavoring Chemicals on Free Radical Production.

Implementation of the Tobacco Control Act in 2009 banned characterizing flavors in cigarettes (except menthol and tobacco), but substitution has occurred by the continued availability of alternative flavored products (i.e., flavored little cigars). Little is known about how flavorants in noncigarette tobacco products impact human health. Thus, we investigated the impact of flavorants on free radical production in the mainstream smoke of little cigars. Gas- and particulate-phase free radical yields in mainstream smoke generated from 12 commercial little cigar brands and research little cigars and cigarettes were measured via electron paramagnetic resonance spectroscopy using the International Organization of Standardization (ISO) smoking protocol. Flavorants were extracted from unsmoked little cigars and analyzed by gas chromatography-mass spectroscopy. Gas- and particulate-phase radical yields from little cigars ranged from 13.5 to 97.6 and 0.453-1.175 nmol/unit, respectively. Comparatively, research cigarettes yielded an average of 4.9 nmol gas-phase radicals/unit and 0.292 nmol particulate-phase radicals/unit. From the products, 66 flavorants were identified, with each brand containing 4-24 individual flavorants. The free radical content was strongly correlated with the number of flavorants present in each cigar (r = 0.74, p = 0.01), indicating that highly flavored little cigars may produce higher levels of toxic free radicals. The presence of the flavorant ethyl methylphenylglycidate (strawberry) was associated with >2-fold higher levels of GP radicals (p = 0.001). Our results show that free radical delivery from little cigars is greater than that from research cigarettes and provide empirical evidence for the harmfulness of flavored tobacco products. Additionally, it demonstrates that flavorants present in combustible tobacco products can influence the levels of free radicals produced. Therefore, future tobacco product standards should consider little cigars.

Pengaruh Gratis Ongkos Kirim, Diskon dan Online Customer Review Terhadap Keputusan Pembelian Konsumen Tiktok Shop

Development of Technology Over the past few years, technology has advanced rapidly and will continue to do so indefinitely. In Indonesia today, online shopping has emerged as a trend and option for acquiring a wide range of desired goods. This study aims to determine how free delivery, limits, and online customer surveys influence purchase decisions on the Tiktokshop Commercial center. Comparative causality is used in this study. This study uses a type of quantitative data because the presented data are related to numbers or scoring. Customers who use TikTok Shop are the focus of this study. Subsequently, the plan of this study utilizes a quantitative methodology, utilizes a coincidental examining technique, and afterward utilizes a non-likelihood testing strategy to make a populace and an example. The study reveals that TikTok Shop purchase decisions are influenced simultaneously by free shipping, discounts, and online customer reviews. The connection between free transportation, limits and online client audits is at the same time sure, intending that in the event that the general factors of free delivery, limits and picture are improved, the buy choice will increment.

Grocery Delivery to Support Individuals With Type 2 Diabetes: Protocol for a Pilot Quality Improvement Program.

People with low income are disproportionately affected by type 2 diabetes (T2D), and 17.6% of US adults with T2D experience food insecurity and low diet quality. Low-carbohydrate eating plans can improve glycemic control, promote weight loss, and are associated with improved cardiometabolic health and all-cause mortality. Little is known about supporting low-carbohydrate eating for people with T2D, although food-as-medicine interventions paired with nutrition education offer a promising solution. This program aims to support the initiation of dietary changes by using grocery delivery and low-carbohydrate education to increase the quality of low-carbohydrate nutrition among people with T2D and food insecurity. This program was a nonrandomized pilot conducted at 21 primary care practices in Michigan. Adults with T2D and food insecurity or low income were eligible to enroll. Patients were referred by primary care clinic staff. All participants received the 3-month program, which included monthly US $80 credits for healthy foods, free grocery delivery from Shipt, and low-carbohydrate nutrition education. Food credits were restricted to the purchase of healthy foods. Education materials, developed in collaboration with providers and patients, included print, digital, interactive web, and video formats. At enrollment, participants completed a survey including demographics, diabetes health, diet and physical activity, and diabetes management and knowledge. After the 3-month program, participants completed a survey with repeat assessments of diabetes health, diet and physical activity, and diabetes management and knowledge. Perspectives on participant experience and perceived program impact, food purchasing behaviors, and use of educational materials were also collected. Diabetes health information was supplemented with data from participant medical records. We plan to perform mixed methods analysis to assess program feasibility, acceptability, and impact. Primary quality improvement (QI) measures are the number of patients referred and enrolled, use of US $80 food credits, analysis of food purchasing behavior, participant experience with the program, and program costs. Secondary QI measures include changes in hemoglobin A1c, weight, medications, self-efficacy, diabetes and carbohydrate knowledge, and activity between baseline and follow-up. This program started in October 2022. Data collection is expected to be concluded in June 2024. A total of 151 patients were referred to the program, and 83 (55%) were enrolled. The average age was 57 (SD 13; range 18-86) years, 72% (57/79) were female, 90% (70/78) were White, and 96% (74/77) were of non-Hispanic ethnicity. All participants successfully ordered grocery delivery during the program. This pilot QI program aimed to improve diet quality among people with T2D and food insecurity by using grocery delivery and low-carbohydrate nutrition education. Our findings may help inform the implementation of future QI programs and research studies on food-as-medicine interventions that include grocery delivery and education for people with T2D. DERR1-10.2196/54043.

The Influence of Discounts and Free Delivery Cost on Purchasing Decisions for Miliki Hijab Products in E- Commerce Shopee in East Java

The aim of this research is to determine the effect of discounts and free delivery cost on purchasing decisions for hijab products on Shopee e- commerce in East Java. The population in this study is consumers who own hijabs in East Java who have made purchases through the Shopee application. The sample in this study was 90 respondents. taken using a purposive sampling technique, namely sampling based on criteria. The sample consisted of respondents who had purchased hijab products in East Java via the Shopee application. The data used in this research are primary and secondary data. The analysis technique used in this research is (PLS) with validity testing, reliability testing and hypothesis testing. The results of this research prove that: (1) Discounts have a positive and significant effect on purchasing decisions. (2) Free Delivery Cost has a positive and significant effect on purchasing decisions.

Competition for territories under the switching cost

ABSTRACT This study considers an effective policy to mitigate market powers held by retail liquefied petroleum gas distributors in Japan. A bilateral spatial competition model is constructed to analyse the effect of switching costs of consumers on retail competition in designated areas where stores provide free delivery service at uniform prices. Model analysis shows that, at equilibrium, stores have exclusive delivery areas which are their natural territories given endogenously. If stores commit to their territories, promoting competition with the adjacent market would be effective. Whereas, if stores do not commit, policies to lower the switching cost are effective.

Characteristics of online shopping behaviour among Tunisians consumers

IntroductionDuring the COVID-19 pandemic confinement, the number of people shopping online has increased all over the word. To date, little is known about the online shopping behaviours of Tunisians consumers.ObjectivesEvaluate the characteristics of internet shopping among Tunisian consumers.MethodsA cross-sectional, descriptive and analytical study was conducted among subjects who had already made at least one online purchase. Data was collected using a self-questionnaire published by GOOGLE FORMS. We used a survey form collecting socio-demographic data, personal history and characteristics of online shopping behaviour.ResultsA total of 137 participants aged 34.62 ± 9.82 years took part in this study.All participants had made at least one online purchase, with 43.8% (N=60) purchasing “More than once a year”. The products purchased were most often textiles and shoes (50.4%; N=69). The main reasons consumers gave for buying online were special offers (37.2%, N=51), reduced prices (25.5%, N=35) and free delivery (14.6%, N=20). Almost half of the participants (N=63; 46%) said that they had visited physical shops less since they started shopping online. Regarding the average online shopping budget, 44.5% of consumers (N=61) spent less than 50 dinars/month and 18.2% (N=16) did not use all the products they bought online. Almost half of participants (N=68, 49.6%) feared that their credit card information would be at risk. The majority of respondents (88.9%) thought they might receive a faulty product following online shopping.ConclusionsOur study has enabled us to identify certain factors that may act as a blocker for online purchasing. So that, stablishing strategic actions for the continuous improvement of online shopping services with the reduction of subjectivity in customer perception will be helpful.Disclosure of InterestNone Declared

Abstract 761: The relationship between ANGPTL4 and epidermal malignant transformation

Abstract High body mass index (BMI) is a risk factor for several types of cancers. Although epidemiology suggests obesity is negatively associated with non-melanoma skin cancer (NMSC), bariatric surgery has been shown to reduce the risk, suggesting a possible role of adipose tissue in the initiation and promotion of skin cancer. To gain mechanistic insight into how adipose tissue drives cutaneous carcinogenesis, we cultured non-tumorigenic mouse keratinocytes (JB6 P+ cells) with or without factors released from murine visceral adipose tissue (mFTF) and performed RNA-Sequencing. Published work demonstrated mFTF induces anchorage-independent cell growth, a surrogate marker for malignant transformation. Transcriptomic analysis demonstrated a significant induction of Angptl4 mRNA in JB6 P+ cells cultured with mFTF for 3 and 8 hours compared to the vehicle-treated cells. ANGPTL4 is an endogenous inhibitor of lipoprotein lipase that modulates free fatty acid delivery to adipose tissue and oxidative tissues such as muscle and liver. The C-terminal protein demonstrates tumor-associated activities such as angiogenesis, metastasis, protection against anoikis, and enhancement of cell survival. Therefore, we hypothesized that the induction of this gene promotes malignant transformation. RNA-seq data was validated in multiple cell models, including primary keratinocytes with human adipose tissue. Immunohistochemistry was used to assess ANGPTL4 expression in 37 actinic keratosis (pre-malignant) and cutaneous squamous cell carcinoma (cSCC) from patients with different BMIs (18.6 - 49.5). Notably, ANGPTL4 was only observed in the suprabasal epidermal layers in normal skin. For samples containing both lesional and perilesional skin, there was an increase in ANGPTL4 expression in the lesional epidermis relative to the normal perilesional skin. Furthermore, ANGPTL4 expression increased from transition to actinic keratosis to cSCC in situ, suggesting that ANGTL4 is induced during malignant transformation as observed in our pre-clinical models. Interestingly, once cSCC developed an invasive component, ANGTPL4 expression was lost in the invasive keratinocytes but persisted in the in situ component. There was no association between ANGPTL4 expression and BMI in lesional tissue. These data suggest that targeting ANTPLT4 may be a novel therapy for the prevention of skin cancer and that ANGPTL4-high patients or cancer patients with obesity may be a critical demographic for potential risk assessment or therapeutic intervention. Future studies will determine the impact of knocking out ANGTPL4 in our models of malignant transformation. Citation Format: Nat Ato Yawson, Jonathan D. Diedrich, Karen T. Liby, Jesse Veenstra, Jamie Jenna Bernard. The relationship between ANGPTL4 and epidermal malignant transformation [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2024; Part 1 (Regular Abstracts); 2024 Apr 5-10; San Diego, CA. Philadelphia (PA): AACR; Cancer Res 2024;84(6_Suppl):Abstract nr 761.

Spatial and Socioeconomic Inequalities in Cesarean Section Deliveries in Urban Settings in Dakar, Senegal.

As part of an initiative aimed at reducing maternal and child mortality, Senegal implemented a policy of free Cesarean section (C-section) since 2005. Despite the implementation, C-section rates have remained low and significant large disparities in access, particularly in major cities such as Dakar. This paper aims to assess C-section rates and examines socioeconomic inequalities in C-section use in the Dakar region between 2005 and 2019. This study incorporates data from various sources, including the health routine data within District Health Information Software 2 (DHIS2) platform, government statistics on slum areas, and data from Demographic and Health Surveys (DHS). A geospatial analysis was conducted to identify locations of Comprehensive emergency obstetric and Newborn Care (CEmONC) services using the Direction des Travaux Géographiques et Cartographiques (DTGC) databases and satellite imagery from the Google Earth platform. The analytical approach encompassed univariate, bivariate, and multivariate analyses. The C-section rate fluctuated over the years, increasing from 11.1% in 2005 to 16.4% in 2011, declined to 9.8% in 2014, and then raised to 13.3% in 2019. The wealth tertile demonstrated a positive correlation with C-sections in urban areas of the Dakar region. Geospatial analyses revealed that women residing in slum areas were less likely to undergo C-section deliveries. These findings underscore the importance of public health policies extending beyond merely providing free C-section delivery services. Strategies that improve equitable access to C-section delivery services for women across all socioeconomic strata are needed, particularly targeting the poor women and those in urban slums.

Orthopaedic practice in Indian secondary care - Exploring the notion of ‘integrated care’ from the perspectives of healthcare professionals and patients, with strategies for implementation

For the duration of my medical elective, I was placed in a government hospital by the name of Loknayak Jai Prakash Narayan Hospital. It specialises in trauma and orthopaedics, and is one of four government hospitals in Patna- the state capital of Bihar. My supervisor subspecialises in the hip and knee joint. Most patients belong to the lower socioeconomic classes and therefore rely on free delivery of care. During this essay I will reflect upon my firsthand experiences, as well as explore the existing literature, to highlight the importance of integrated care. Orthopaedics is a speciality that brings together many diverse groups of healthcare professionals. The NHS has always placed a strong emphasis on continuity of care by designing standardised frameworks. Coming from an alternative perspective, I seek to observe whether patients and healthcare professionals in Bihar also understand the concept of integrated care. Using examples I will look back to see how various teams work together within the Indian secondary care context.

Subscription Pricing for Free Delivery Services

Many firms that offer home delivery of products purchased online now provide consumers the option of subscribing to a membership plan for free delivery of limited or unlimited number of orders instead of customers paying delivery charges for each order. This paper seeks to understand the benefits to firms and consumers of introducing such free-delivery subscription (FDS) plans to complement their traditional pay-for-delivery (PFD) option, characterize the firm's optimal FDS subscription pricing strategy, and study the effects of product, consumer, and market characteristics on the subscription fees and firm's profits. We develop and analyze an economic model that incorporates salient features of product delivery settings that prior models of subscription pricing do not fully capture. The features include simultaneous availability of PFD and FDS options, lift in a consumer's demand when she switches from PFD to FDS, the possibility of attracting new consumers when the firm introduces FDS, and order batching by customers due to per-order delivery charges and free-delivery order allowances. Our utility-based approach to model consumers’ purchasing choices incorporates consumer heterogeneity both in terms of their utility for the product and their shopping preference under the PFD option. For homogeneous consumers, we show that introducing a FDS plan raises the firm's profit, establish the optimality of offering unlimited free-delivery allowance, and analyze comparative statics. With multiple customer types, our analysis of two subscription pricing strategies for FDS plans—a single “Universal” plan and multiple “Tiered” plans with varying subscription fees and free-delivery limits—leads to several interesting insights on delivery pricing strategies, as well as drivers and sensitivity of the optimal policy, profits, and number of subscribers. We supplement this analysis with extensive computational experiments that reveal a substantial increase in profits when a firm adds one or more FDS plans to its PFD option even though the optimal subscription fee(s) only covers part of the firm's actual shipping costs. These results also permit us to gauge the influence and understand the trends in the profitability of the Universal and Tiered plans as various parameters change.

Digital Apparel Try-Ons: A Technological Odyssey into the World of Virtual Dressing Rooms and Consumer Engagement

This individual can now enjoy internet shopping whenever they want and from anywhere in the world thanks to the invention of smartphones and tablets. Online shopping has unquestionably taken the place of conventional methods for purchasing apparel and daily necessities. People benefit from a reputation as they pick internet buying. Almost all online retailers offer payment on delivery, free shipment, and special rates these days. These internet merchants have eliminated the hassles of parking, stuck in traffic, and standing in line to make purchases. They have also helped folks who consistently lament their lack of time. This is the primary justification for why most consumers now shop online. They may easily access a wide choice of affordable prices here, and they also get quick customer service and free home delivery. There is no denying that these are a few of the alluring aspects that draw customers in. Even though there is a minor problem that can make people lose interest in online buying, they might not be able to try on garments in such situations. By establishing a virtual changing room setting, the aim is to improve accessibility and time efficiency for trying on clothing. Our proposed methodology consists of three main components: skin color recognition, model alignment, and user image extraction from the video stream. Through user extraction, we may create an augmented reality environment by taking the user area out of the video stream and superimposing it on top of a simulated world within the user interface. To match the 2D cloth models with the use of scaling, rotation, and positioning using the 3D locations of the joints.

The environmental impact of buying groceries online/offline pre and during COVID-19. Any changes?

COVID-19 has represented a watershed in people's lifestyle. One important consequence has been the change in how people buy groceries online/offline that represent the most frequent shopping-related trip any household performs. Since this has substantially different transport and environmental implications, it is crucial to investigate what are the COVID-19-induced variations. This paper estimates both travel and environmental impacts grocery channel choice implies by comparing, in a diachronic fashion, the pre and during COVID-19 situation in Norway, considering alternative scenarios describing different service configurations for each channel considered. Stated preferences are used to estimate market shares for grocery purchase distinguishing between different channels: in-store, home delivery and click&pick. The robust comparative analysis between the two time periods is guaranteed by the use of the same methodological approach in the same geographical context. Results show that total emissions are lower during the pandemic and adopting a free delivery strategy not only increases home delivery market shares but also produces the lowest level of CO2 emissions regardless of COVID-19. The results obtained are particularly relevant in the "new normal" the world is experiencing both from a public policymaking perspective, when promoting transport-related interventions to curb emissions, and from a private standpoint, when customising market strategies to increase sales and profits.

ANALYSIS OF TWITTER USER INTERACTIONS USING SOCIAL NETWORKS AT PAYDAY SALE EVENTS ON THE MARKETPLACE

The goal of this study was to ascertain the marketplace companies' commitment to implementing SCRM on social media and to identify patterns of engagement, interaction, and communication between Twitter users and the marketplaces Shopee, Tokopedia, and Lazada that emerged on social media at payday sale events. The Social Network Analysis (SNA) approach is being used in this qualitative study. Twitter users in Indonesia are the focus of this study. The users of Tokopedia, Shopee, and Lazada are the research population. Dictionary, Notepad++, Wordij, and Gephi are supporting tools used in this study together with Jupyter Notebook. The Shopee Marketplace is superior and performs better, according to an analysis of network features. According to the analysis, the Shopee marketplace has a broader network. According to this study, many consumers utilize Shopee as their online shopping destination, particularly during payday sale events when each marketplace offers alluring discounts and free delivery.

Pengaruh Kupon Gratis Ongkir dan Kelengkapan Produk terhadap Keputusan Pembelian pada Platform Tiktok Shop di Kota Sampit

Web based shopping is a movement or action that is in many cases completed by different age bunches since it is not difficult to do and saves time. The goal of this study was to find out how variables related to free shipping and product completeness, free shipping coupons, and free shipping coupons combined influenced consumers' choices when making purchases. This examination is a quantitative report utilizing an example of 100 respondents who have made buys through the TikTok Shop stage. Questionnaires were distributed for data collection. The testing assurance method utilized was side purposive. The information investigation strategy utilized is different straight relapse examination. The consequences of the review show that the two X factors, in particular Free Delivery Coupons and Item Fulfillment, impact Buy Choices on the TikTok Shop Stage.