Given \(n,m\in \mathbb {N}\) and a simply connected uniform domain \(U\subset \mathbb {C}\) with a sufficiently smooth boundary \(\partial U\), we study the \(C^{\ast}\)-algebra $$\begin{aligned} {\mathfrak B}_{U,n,m}({\mathfrak L}):=\mathrm{alg}\{aI,B_{U,1},\ldots ,B_{U,n},\widetilde{B}_{U,1},\ldots ,\widetilde{B}_{U,m}: a\in {\mathfrak X}({\mathfrak L})\}, \end{aligned}$$generated by the operators of multiplication by functions in \({\mathfrak X}({\mathfrak L})\), by the poly-Bergman projections \(B_{U,1},\ldots ,B_{U,n}\) and by the anti-poly-Bergman projections \(\widetilde{B}_{U,1},\ldots ,\widetilde{B}_{U,m}\) acting on the Lebesgue space \(L^2(U)\). The \(C^{\ast}\)-algebra \({\mathfrak X}({\mathfrak L})\) is generated by the set \(SO_{\partial} (U)\) of all bounded continuous functions on U that slowly oscillate at points of \(\partial U\) and by the set \(PC({\mathfrak L})\) of all piecewise continuous functions on the closure \(\overline{U}\) of U with discontinuities on a finite union \({\mathfrak L}\) of piecewise Dini-smooth curves that have one-sided tangents at every point \(z\in {\mathfrak L}\), possess a finite set \(Y={\mathfrak L}\cap \partial U\), do not form cusps, and are not tangent to \(\partial U\) at the points \(z\in Y\). Making use of the Allan-Douglas local principle, the limit operators techniques, quasicontinuous maps, and properties of \(SO_{\partial} (U)\) functions, a Fredholm symbol calculus for the \(C^{\ast}\)-algebra \({\mathfrak B}_{U,n,m}({\mathfrak L})\) is constructed and a Fredholm criterion for its operators is obtained.