The longitudinal dynamic performance of long-span bridges with passive vibration control devices when subjected to vehicle and seismic loads has raised extensive attention of the civil engineering community. This study aims to provide numerical and experimental assessments of the dynamic performance of a railway suspension bridge with the Combined Viscous-Steel Damping System (CVSDS) under various excitations. The deck is simplified to a single-degree-of-freedom (SDOF) system according to the longitudinal vibration characteristics of the suspension bridge. The Dynamic Equation Method (DEM) and Fourier Expansion Method (FEM) are suggested for the equivalence of the spatiotemporal variable train loads to horizontal excitations. A simplified two-stage analytical model is proposed to simulate the restoring force characteristics and fuse-lock function of the CVSDS. Shake table tests are conducted to further illustrate the feasibility of the simplified model and evaluate the effectiveness of the CVSDS. The results indicate that the SDOF system is reasonable and satisfactory in simulating the deck displacement. The two-stage working mechanism of the CVSDS is verified by both the simulation and experiment, i.e. the viscous fluid damper works under train loads and the steel yielding damper operates under earthquakes. The vibration mitigation effectiveness of the CVSDS is remarkable.