Paint Formulations Research Articles

Efficacy of zinc and copper oxide nanoparticles as heat and corrosion-resistant pigments in paint formulations

This study focuses on the synthesis of zinc and copper oxide nanoparticles using green methods by plant extracts. The resulting metal oxides were analyzed using FT-IR spectroscopy, TGA, TEM, zeta potential and assessed for their efficacy as pigments based on properties such as Hydrogen Ion Concentration, Oil absorption, Moisture Content, Fineness of grinding, Bleeding, and loss on ignition. The results confirmed that the prepared ZnO and CuO nanoparticles exhibited the formation of nanoparticles in the range of 10–40 nm with potential as pigments. Two paint formulations incorporating these nanoparticles and silicon resins as binders were tested for physico-mechanical attributes, chemical resistance, heat resistance, and corrosion resistance of the dry paint films. The study found that the films containing the prepared oxides demonstrated excellent performance, with no damage or color alteration observed after exposure to temperatures up to 500 °C. Moreover, the paint films containing ZnO nanoparticles showed superior efficiency after a 500 h salt spray test compared to those with CuO nanoparticles. These findings suggest that the synthesized mixed oxide nanoparticles are promising candidates for heat-resistant pigment applications.

Novel antifouling paint formulation based on Ca2​Cr2O5​ and CaMnO3​ NPs as a protective pigment

This work focused on the preparation of novel antifouling paint based on Ca2Cr2O5 and CaMnO3 NPs as a safe protective pigment which were replaced with cuprous oxide. Three paint formulations were prepared for comparison, a blank formula without an antifouling agent (F1), a commercial antifouling formula based on 100% cuprous oxide as an antifouling agent (F2), and AF formula based on 75% Ca2Cr2O5 and CaMnO3 NPs and 25% Cu2O. The high performance and durability of the paints based on the prepared pigments were evident from their impact resistance, adhesion, pending, hardness, and chemical resistance, which were compared to the blank formula (F1). The corrosion resistance of the painted films was also investigated using the salt spray test method, and the results were promising compared to the blank and standard formulations. All painted steel plates were exposed to seawater through field tests in the Suez Canal at Port Said for up to 6 months. The results showed that the paints based on F2 and F3a, b enhanced the antifouling activity through six months of exposure. The obtained results demonstrated greater efficiency of the painted steel-based F3a than F1 and F3b, and being comparable to the standard formula (F2).

Characterization and application of composite resin of natural rubber latex and polystyrene waste as a binder for water-resistant emulsion paint formulation

Sustainable production of efficient and low-cost coating materials from recycled plastic wastes will have a significant impact on economic advancements in paints and coatings, as well as waste management. Polystyrene waste was reduced to a resin, which was further modified by blending with natural rubber latex (NRL). The recycled polystyrene resin (rPS) and NRL formed homogeneous composite resins (rPS-NRL) blends in various ratios, and the changes in some physicochemical properties of the resins were studied. The rPS-NRL blended in different ratios exhibited higher density (0.83–0.92 g/cm3), refractive index (1.401–1.438), viscosity (935–1287 cP), elongation (5–18 %), and melting point (184°C–217.5°C), as well as lower moisture uptake (1.1–0.88 %) and faster drying time (32–19 min), compared to the rPS resin. Changes in functional, structural, and morphological characteristics of the resins were studied using Fourier transformed infrared (FTIR) spectrometer, X-ray diffractometer (XRD), scanning electron microscope (SEM) and thermogravimetric analyzer (TGA-DTA). The results indicated molecular interactions between NRL and the rPS resin, which form the basis for the unique physicochemical properties of the composite resin compared with the pristine rPS and NRL resins. White (CaCO3) pigmented emulsion paint produced using the rPS-NRL composite resin as binder was tested in comparison with paint produced using the conventional polyvinyl acetate (PVA) binder, where the rPS-NRL paint exhibits superior properties, including outstanding resistance to water.

IR reflective performance of ZnO: Dy pigment on glass surface

In this paper, we have discussed the heat reflective properties of ZnO: Dy3+ pigment synthesized by the combustion method and co-precipitation method. The phase purity and crystalline nature of the prepared pigment have been studied using XRD and SEM. The IR-reflective properties of the pigment DRS have been measured. A paint formulation of the ZnO: Dy3+ pigment was prepared in alkyd resin. The performance of the heat-reflective paint has been investigated by coating the glass surface. From the present investigation, it is seen that the prepared ZnO: Dy3+ pigment is well suited to increase the IR reflectance to cool the surface.

Fast microwave carbonization of aluminum-coated plastic wastes and perspectives: The examples of CDs and snack bags

Aluminum-coated plastics, such as CDs and snack bags, are widely used and consumed around the world. Since millions of CDs and trillions of snack bags end up in landfills and oceans as plastic waste every year, we suggest here an easy, fast, and cost-effective method for transforming this significant volume of garbage into added-value carbon using microwave technology. The proposed method differs from existing time- and energy-consuming pyrolytic processes employed in the traditional carbonization of this sort of waste. Conceptually, direct irradiation of the aluminum-coated plastic items in a domestic microwave oven heats up the metallic coating, thus triggering carbonization of the plastic substrate. The resulting carbon, which is characterized by means of X-ray diffraction (XRD), Raman spectroscopy, X-ray photoelectron spectroscopy (XPS) and scanning electron microscopy (SEM) techniques, has structural similarities to carbons produced from CDs and snack bags using pyrolytic methods. In other words, the microwave technique produces similar effect, but it is faster and more energy efficient. We finally demonstrate some practical uses of the derived materials in gunpowder production, carbothermal production of metals and grey paint formulations.

Composite Paints with High Content of Metallic Microparticles for Electromagnetic Shielding Purposes

This paper describes the technological process used to manufacture composite paints with a high content of metallic microparticles (Al and Fe) for automotive electromagnetic compatibility applications. The thickness of the deposited paint layer was larger for paints with a greater metal content, regardless of the plastic support used for paint deposition. The roughness of paint layers with a greater content of metal particles was about 30%–35% higher than that of layers with a lower metal particle content, regardless of the metal type. The surface roughness of paint layers containing Al was at least 2.5-times higher than that of paint layers containing Fe, an aspect that could be explained by the better formulation of the paint containing Fe. The dielectric loss and conductivity values crucially depend on the plastic substrate used, meaning that the dipolar polarization of the substrate enhances the effect of conductive paints. Based on the dielectric properties measured at 10 kHz, the optimal recipe for efficient electromagnetic compatibility was found to be 20 wt.% Fe powder, deposited on a sandblasted polycarbonate (PC) substrate. It is expected that formulations of paints with a high percentage of metallic particles will effectively compete with traditional plastic metallization technologies.

Nano-enhanced antifungal paint: Harnessing nanoparticle-based fungicides for enhanced durability and protection

The present study focuses on the development of nano particle-based fungicide formulations using organic compounds like Carbendazim, known for their broad-spectrum fungicidal activity and enhanced stability compared to traditional organic fungicides. The utilization of nanoparticles in anti-fungal paints represents a promising avenue with significant potential. The process involves obtaining a dispersion of fungicide molecules at the nano scale using a top-down approach, which entails reducing the size of larger particles to Nano-scale dimensions. The resulting nano-based fungicide dispersion offers several advantages, including a high surface-to-volume ratio, easy surface medication, uniform particle size distribution, and excellent stability. These properties make it well-suited for integration into paint formulations, signaling advancements in paint technology to meet the growing demand for durable, long-lasting, and environmentally friendly coatings. This aligns with the industry's focus on sustainability and performance enhancement. Overall, employing a top-to-bottom approach for obtaining fungicide active molecules in the nano range, with techniques such as wet milling, proves effective in enhancing paint formulations for improved efficacy and longevity.

Application of ZnAl layered double hydroxides for the formulation of stable and safe cosmetic pigments

Purpose This study aims to produce composite pigments, including SHS/ZnAl-LDHs, IDS/ZnAl-LDHs and SNND/ZnAl-LDHs, with improved coloration, enhanced photostability and thermostability and biocompatibility. Design/methodology/approach The chemical structures of the composite pigments were characterized by X-ray diffraction spectroscopy and Fourier transform infrared spectroscopy. Photostability and thermal stability were assessed using ultraviolet-visible spectroscopy and colorimetry. The coverage of the dyes was determined through black-and-white tile testing, and specific RGB values were used to indicate color expressiveness. Finally, a four-color eyeshadow was formulated, and safety tests were conducted via human patch test and cellular assays to confirm the safety and reliability of the samples. Findings The experimental results demonstrate an enhancement in the photo and thermal stability of the SHS/ZnAl-LDHs, IDS/ZnAl-LDHs and SNND/ZnAl-LDHs composites, along with their superior performance in terms of covering power and color saturation. These composite pigments also exhibit high safety, making them well-suited for cosmetic applications. Practical implications The composite pigments based on hydrotalcite can be used in the cosmetic industry without causing any harm to the environment and human health. Originality/value The addition of hydrotalcite enables better application of pigments in cosmetics.

A Novel Gum Paint Formulation Derived From Licorice and Triphala: Characteristics and Clinical Significance for Improved Oral Health.

The clinical use of antimicrobial agents for managing aphthous ulcers and periodontal diseases has long been a subject of intensive research by numerous investigators. As concerns over the side effects and antibiotic resistance associated with conventional therapies persist, there has been a concerted effort to explore alternative medicinal approaches. In line with this objective, our study introduces a novel herbal gum paint designed specifically to address the therapeutic needs of individuals suffering from oral ulcers and periodontal diseases. The herbal formulation utilized in our study was prepared using extracts derived from Licorice (Glycyrrhiza glabra) and Triphala, a combination of three fruits: Emblica officinalis, Terminalia chebula, and Terminalia belerica. These ingredients were selected based on their documented medicinal properties. The preparation process involved extraction and formulation techniques optimized for maximum efficacy. Antimicrobial activity was assessed using the bacterial culture method, where the formulation's ability to inhibit the growth of specific bacterial strains relevant to oral health was tested. Meanwhile, cytotoxicity was evaluated using the Brine Shrimp Assay method. Statistical analysis was conducted using a one-way analysis of variance (ANOVA) and Tukey post hoc test to validate the significance of our findings with statistical significance set at p<0.05. The formulation exhibited significant activity against microbes when compared to the control. The cytotoxic activity was present at a concentration of 60 and 80µL, which indicated safe usage within specified concentration ranges, highlighting its potential for clinical application without adverse effects on biological systems. Statistically significant differences were obtained between the antimicrobial activity of the formulated gum paint and the commercial gum paint against Candida albicans species at 25 µL and 80 µL (p=0.00). The study underscores the promising therapeutic potential of the herbal gum paint developed in this research. By harnessing the natural antimicrobial and anti-inflammatory properties of Licorice and Triphala, the formulated gum paint showed efficacy against C. albicans.These findings contribute to the growing body of evidence supporting the integration of herbal remedies into mainstream oral healthcare practices. Future investigations could further elucidate the mechanisms underlying its therapeutic actions and explore its broader clinical applications in diverse patient populations.

INTEGRATED EMULSION PAINTS DERIVED FROM THREE POLYVINYL ACETATE (PVA) GROUNDNUT OIL

A modified paint was produced in this research to supplement and substituteproducts by tender small-scale private paint factories, in an era of increasing demand of paints by the nation’s alarmingly growing building technology. The research was aimed at the formulation of an emulsion paint with the aid of polyvinyl acetate mixed with Groundnut oil as a binder by reducing volatile organic compounds and to determine the major physical parameters such as drying time, period of elongation, density, refractive index, adhesion, pH, and chemical resistance. The result obtained showed increase of dry to hard from Pure PVA paint (90.23 minutes) followed by Gombe PVA paint (105.5 minutes) to Taraba PVA paint (110.00 minutes). The drying time of the paint samples was in this order Taraba PVA paint (80.0 min) &gt; Gombe PVA paint (75.5 min) &gt; Pure PVA paint (75.23 min). The dry to touch was in the decreasing order: Taraba PVA paint (56.2 min) &gt; Gombe PVA paint (53.4 min) &gt; Pure PVA oil (49.15 min). The density (g/cm3) showed that Gombe PVA paint (1.16) &gt; Pure PVA paint (1.30) &gt; Taraba PVA paint (1.10). The solubility test for both Taraba PVA Groundnut paint and Gombe PVA Groundnut derived paint are practically insoluble in water, while Pure PVA derive paint dissolved in water instantly. All the three formulated paints passed the resistance blistering and flexibility tests. FTIR showed the following functional groups Hydroxyl, Amines, Carboxylic acids, Alkylhallides, Ketones and Aldehydes at specific wavelength are present in paints that serves as...

Indoor paint life cycle particle release: Safer-by-design products and the importance of choosing the right formula

In 2020, the European Commission published a regulation that states all producers of white paints containing titanium dioxide (TiO2) must provide a warning label on their products. Exposure during the production and application of products containing TiO2 can be harmful, and therefore these products must be labeled as “may cause cancer.” The paint industry is a major user of TiO2 pigment. This study focuses on pigment release from three TiO2-based paints and discusses the effect of paint formulation, more precisely the Pigment Volume Concentration (PVC), to predict TiO2 pigment release from the paints during a simulated use phase and at the end of life (EoL). The use phase considered mild abrasion of painted panels that simulated cleaning or touching. The EoL phase was studied using leaching tests simulating landfill disposal. TiO2 release during both activities was evident with a high discrepancy between the three paints. While dry rubbing was similar for all paints, activities involving water present a high release link to paint matrix degradation. The paint pigment volume concentration and the paint permeability determines the TiO2 release during wet rubbing and leaching. This work represents an attempt to identify the paint permeability as a matrix-related parameter to predict TiO2 release and a way to use of this parameter to develop safer products.

Assessing the effectiveness, biosafety, and resident’s perception of a micro-encapsulated propoxur paint against Aedes aegypti: a field trial in a dengue-affected community of Sonora, Mexico

Mosquito-borne diseases remain a major public health concern in the Region of the Americas. Concerning dengue, Mexico ranked as the third American country with the highest number of cases in 2023, following Brazil and Peru. In this sense, the development and production of safer, eco-friendly, cost-effective, more efficient, and target-specific insecticides have become essential in disease control strategies. This study aimed to assess the effectiveness and safety of indoor micro-encapsulated propoxur paint against Aedes aegypti, estimate residents' exposure via cholinesterase levels, and gauge resident perceptions in the rural village Poblado Miguel Alemán (PMA), Sonora, Mexico. Houses in PMA were organised into four blocks for a field trial, with different treatments on interior walls: 1) full insecticide paint coverage; 2) insecticide paint applied up to 1 meter; 3) full indoor residual spraying; and 4) no treatment (control). Mosquito surveys were conducted before and after interventions. Blood samples from residents were analysed for cholinesterase levels, while perceptions were gathered through a questionnaire. Aedes resting density correlated closely with the paint formulation and coverage. Full-surface insecticide paint showed the greatest reduction. Both paint interventions notably impacted Aedes breeding, with substantial reductions in House Index (20.1% IP, 31.2% IP 1 m) and Container Index (51.8% IP, 61.7% IP 1 m) compared to the control over one year. Post-intervention blood cholinesterase activity remained within acceptable limits. Over 80% of residents expressed satisfaction with the interventions. The use of propoxur paint proves to be a safe, effective, and well-accepted method for decreasing Ae. aegypti populations in urban areas.

Formulation of tattoo paints from the assemblage of the Upper Paleolithic site of Ushki V (Kamchatka)

In recent times, the practice of body modification in sociocultural, psychological, and art studies contexts has gained a new impetus for research. This article presents the results of the analysis of pigments found on the sur-face of stone artifacts identified as tattooing tools from the assemblage of layer VII of the Upper Paleolithic site of Ushki V (13–12 ka calBP, Kamchatka Peninsula). The aim of this study is to reconstruct the formulation of paints discovered on the surface of stone tools from the collection of Ushki V, that could have been used for tattooing. The reconstruction was carried out by means of determining the composition and microstructure of the paints using scanning electron microscopy and energy dispersive X-ray spectroscopy (SEM-EDX). The conclusions about the structure of colouring substances and the composition of paints are based on the element mapping method, which allows determination of the relationships of chemical elements and establishing the chemical com-position of individual components of the microstructure. Seven samples of red and yellow paint from the surface of six tools (carvers) have been thoroughly analysed. As a result, it has been found that three recipes were used for the manufacture of the pigments. The first (red paint) was based on mixing crushed mineral pigment (hema-tite) with organic binder of animal or vegetable origin. The second (yellow paint) implied the use of limonite, or-ganic binder and a thickener (aluminosilicate material or crushed bone). The third recipe (dark orange paint) in-cluded the compound of limonite and organic binder without thickener. The comparison of the formulations with previously obtained data on the analysis of paints from Ushki V allows for the conclusion that there were continu-ous technological traditions determined by the desired color and purpose of the paint. It has been established that the formulations have analogies both among the assemblages of other Stone Age sites of Eurasia and in ethno-graphic materials. Theoretical and practical significance of this research lies within extending of focused studies of the culture of peoples of the North and initiating of comparative research into similar Late Paleolithic and Neolithic complexes in the territories adjacent to Kamchatka and in the New World.

Novel nano magnesium oxide modified hybrid emulsion for antimicrobial coating

Purpose The purpose of this paper is to develop an inorganic-organic hybrid emulsion polymer using grafted hyperbranched alkyd modified with nanometal oxide and to study the performance of the developed hybrid emulsion in paint formulation with respect to antimicrobial and other properties. Design/methodology/approach A novel hybrid emulsion polymer was synthesized by grafting of vinyl acetate (VAM), vinyl ester of versatic acid (VeoVa 10) monomers onto hyperbranched alkyd resin and incorporation of nano magnesium oxide (MgO) into the hybrid resin matrix during dispersion of resin in water. Subsequently, paint was prepared by using this hybrid emulsion followed by a performance study. Findings The performance of nano MgO modified into VAM and VeoVa 10 grafted hyperbranched alkyd resulted in unique properties of coating especially antimicrobial activity. Research limitations/implications In the present study, soya fatty acid, polyol and di basic acid have been used to prepare hyperbranched alkyd by condensation polymerization. Monomers like VAM and VeoVa 10 used for grafting onto hyperbranched alkyd and nano MgO have been incorporated into hybrid resin matrix during emulsification of hybrid resin in water. Practical implications Grafting of VAM and VeoVa 10 onto hyperbranched alkyd along with in situ incorporation of nano MgO in resin matrix is an effective technique to achieve excellent coating properties. Originality/value Nano MgO modified VAM and VeoVa 10 grafted hyperbranched alkyd-based hybrid emulsion can be used as binder in water-based metal primer, direct to metal (DTM) coating as well as topcoat application. The developed system has antimicrobial properties as well as superior mechanical properties.

Metronidazole mediated potassium iodide as high-performance deterioration retardant for mild steel in an acidic media

As corrosion scientists all over the world struggle to discover new metal deterioration retardant which can close the performance gap created by the legislative banned toxic inhibitors, we present in this research work an azole based drug and its mediation performance with a synergistic agent as ‘green’ metal degradation retardant. The anti-deterioration performance of the azole-based drug, metronidazole (MTN) and its different concentration combinations with potassium iodide (KI) were examined with materials degradation analysis tools such as functional group, nanoindentation, weight loss and electrochemical techniques. MTN alone performed well as an anti-deterioration retardant exhibiting retardation efficiencies (η%) in the range between 73 to 85% at different temperatures and analytical techniques. However, with the introduction of KI, an escalation in (η%) was obtained in the region of 92 to 97%. In addition, improved polarization resistance of chemical retardants on substrate cross sections was achieved, manifested by the resultant elevation in values of polarization resistances (Rp) from 1.54 Ω.cm2 of the blank to 30.61 Ω.cm2 of the optimum concentration, charge transfer resistances, (Rct) improved likewise from 6.03 to 144.07 Ω.cm2 and depreciation in the values of corrosion current densities (Icorr) from 8863.86 to 228.89 µA.cm2. This work describes a method of improving the metal deterioration retardation potentials of an azole compound, bringing out new knowledge on the degradation inhibition properties of MTN and the adsorption process taking place between the substrate and the belligerent environment. We hope it opens the door for the utilization of a mixture of MTN and KI as additives for the formulation of sealants, paints, conversion coatings and primers for ferrous alloys. It also encourages more investigations, to find additives such as suitable activating and accelerating agents for MTN to make It exercise the same or more anti-corrosion potents possessed by the banned hexavalent chromium (vi), benzothiazoles (BTA) and others. Some of these potents are the ability of MTN to function at a wide region of pH and in the moment of coating failure, what can enable an azole-containing coating, to undergo some chemical activities and still maintain the substrate surface integrity?

Cu(II) complexes using acylhydrazones or cyclen for biocidal antifouling coatings

Abstract Copper and copper-based compounds have broad spectrum antimicrobial activity, but concerns about leaching into the environment and toxicity on non-target organisms is leading the use of copper-based coatings being restricted. Our objective was to develop coatings that used the biocidal activity of copper, but with low negative impacts by reducing its leaching into the environment. This study reports the synthesis and characterisation of copper coordinating ligands, their formulation into coatings and testing of their antibacterial activity. A polyacylhydrazone and a series of simple acylhydrazones were synthesised and coordinated to Cu(II), but were considered unsuitable due to either their poor water-solubility or high levels of copper leaching. In an alternative approach, copper was successfully chelated to the tetraazamacrocycle, cyclen, and used to synthesise Cu(II)-cyclen functionalised silica particles, which were successfully combined with commercial paint formulations. These functionalised products showed poor antibacterial activity when incorporated into epoxy coatings, probably due to the low copper content of the formulations. However, these ligands may have other applications, such as removal of heavy metals from contaminated effluent steams.

Radiative Cooling Potential of a Water-Based Paint Formulation under Realistic Application Conditions

Radiative Cooling Potential of a Water-Based Paint Formulation under Realistic Application Conditions

Toward Self-Healing Coatings: Bacterial Survival and Calcium Carbonate Precipitation in Acrylic and Styrene–Acrylic Model Paint Films

Engineered living materials (ELMs) incorporate living material to provide a gain of function over existing materials, such as self-repair. The use of bacteria in ELMs has been studied extensively in concrete, where repair can be facilitated by bacterial ureolytic calcium carbonate (CaCO3) precipitation; however, the study of bacteria in other construction materials is limited. We examined the ability of bacterial species to survive in common latex binder chemistries, a model paint formulation, and through the film-forming process. The longest survival was by bacterial spores of Bacillus simplex str. GGC-P6A, which survive in latex emulsions, a liquid coating composition, and in a dried film for &gt;28 days. Surprisingly, our data show that non-spore-forming Escherichia coli survive at least 15 days in liquid composition, which appear to be influenced by the composition of the outer membrane, nutrient scavenging, and the ability to metabolize toxic acrylate. Spores of GGC-P6A were shown to grow in solid paint films from sites of damage, resulting in crack filling through carbonate precipitation, demonstrating the potential for self-repair through microbially mediated CaCO3 precipitation without directed pH modification. These data suggest that a range of bacterial species, in particular members of Bacilli, may facilitate new applications of bio-augmented, self-healing coating systems.

Designing a highly near infrared-reflective black nanoparticles for autonomous driving based on the refractive index and principle

HypothesisThe development of highly NIR reflective black single-shell hollow nanoparticles (BSS-HNPs) can overcome the Light Detection and Ranging (LiDAR) sensor limitations of dark-tone materials. The crystalline phase of TiO2 and the refractive index can be controlled by calcination temperature. The formation of hollow structure and the refractive index is expected to simultaneously increase the light reflection and LiDAR detectability. ExperimentsThe BSS-HNPs are synthesized using the sol–gel method, calcination, NaBH4 reduction, and etching to form a hollow structure with true blackness. The computational bandgap calculation is conducted to determine the bandgap energy (Eg) of the white and black TiO2 with different crystalline structures. The blackness of the as-synthesized materials is determined by the Commission on Illumination (CIE) L*a*b* color system. FindingsThe hydrophilic nature of BSS-HNPs enables the formulation of hydrophilic paints, allowing the mono-layer coating. With the synergistic effects of hollow structure and the refractive index, BSS-HNPs manifested superb NIR reflectance at LiDAR detection wavelengths. The high detectability, blackness, and hollow structure of BSS-HNPs can expand the variety of LiDAR-detectable dark-tone materials.

Tributyltin (TBT) toxicity: Effects on enteric neuronal plasticity and intestinal barrier of rats' duodenum

Tributyltin (TBT) is a biocide used in the formulation of antifouling paints and it is highly harmful. Despite the ban, the compound persists in the environment, contaminating marine foodstuffs and household products. Therefore, considering the route of exposure to the contaminant, the gastrointestinal tract (GIT) acts as an important barrier against harmful substances and is a potential biomarker for understanding the consequences of these agents. This work aimed to evaluate histological and neuronal alterations in the duodenum of male Wistar rats that received 20 ng/g TBT and 600 ng/g via gavage for 30 consecutive days. After the experimental period, the animals were euthanized, and the duodenum was intended for neuronal histochemistry (total and metabolically active populations) and histological routine (morphometry and histopathology). The results showed more severe changes in neuronal density and intestinal morphometry in rats exposed to 20 ng/g, such as total neuronal density decrease and reduction of intestinal layers. In rats exposed to 600 ng/g of TBT, it was possible to observe only an increase in intraepithelial lymphocytes. We conclude that TBT can be more harmful to intestinal homeostasis when consumed in lower concentrations.