ABSTRACT The Rag Doll Plagues, by Mexican American writer Alejandro Morales, underlines the racial dimension of the environmental crisis while also demonstrating the material interdependence between human and more-than-human worlds through the lens of trans-corporeality. By exploring the material connection between the poisoned body and the environment; the interaction between the marginalized body and nonhuman as subject; and the mutant body’s agency as a “habitat” and “thing,” this paper highlights the evolving and dynamic relationship between the porous human body and various forms of living and non-living entities within and beyond its borders. Morales's plague reminds humanity to break away from narrow, teleological thinking in the face of disaster and to adopt a mode of thought that is interconnected with the world as well as attentive to, and appreciative of, the vitality of non-living entities, thus fostering a nonlinear, open “material ethics”.