Formation Of Palladium Nanoparticles Research Articles

Ultrasound assisted biogenic synthesis of Palladium nanoparticles using Cocculus hirsutus leaf extract: Antimicrobial, anti-inflammatory and catalytic activities

We have synthesized palladium nanoparticles (PdNPs) from aqueous leaf extract of Cocculus hirsutus (CH) by ultra-sonication in an easy, non-toxic, and eco-friendly manner. PdNPs synthesized were analyzed using UV–vis, FT-IR, powder XRD, TEM, and DLS instruments. From UV–vis spectra, the Surface Plasmon Resonance (SPR) signal indicated that the formation of PdNPs. The synthesized PdNPs shows spherical shape, crystalline and polydispersibility nature with a mean particle size of 10±3 nm was observed from XRD and TEM. FTIR analysis reveals the active role of phenolic constituents from CH leaf extract in reduction and surface functionalization of nanoparticles. The stability of the PdNPs was assessed by devious the Zeta potential analysis. The as-prepared PdNPs showed antibacterial efficacy (maximum zone of inhibition is 11.20 mm for S. typhimurium) and antifungal efficacy (maximum zone of inhibition is 32.80 mm for C. albicans) against disease causing human pathogens, strong anti-inflammatory activity for BSA denaturation and blistering catalytic activity against 4-NP reduction up to 5 cycles (6 min; 100 % reduction, rate constant is 0.532 min−1). The potency of the anti-inflammatory activity was found to be 90 % using PdNPs against the standard drug Diclofenac sodium (90 %) for 500 µg/mL. The above mentioned activities were used to evaluate the effectiveness of the PdNPs in treating bacterial, inflammation related conditions and also as an effective catalyst in wastewater treatment.

Environmental Energy Production and Wastewater Treatment Using Synthesized Pd Nanoparticles with Biological and Photocatalytic Activity

AbstractMetallic nanoparticles have attracted great attention in catalytic, medical diagnosis, and treatment research in recent years. The formation of palladium nanoparticles using rosemary (Rosmarinus officinalis L.) extract was carried out using the green synthesis method. The plant was extracted using 70% ethanol by microwave techniques. The novelty of this study is the investigation of the biological activities of green synthesis of Pd nanoparticles, such as DNA cleavage activity, antimicrobial activity, DPPH scavenging activity, and its electro-catalytic performance in alcohol oxidation. Additionally, photocatalytic activities were also evaluated. The characterization of synthesized palladium nanoparticles (Pd NPs) was performed by UV-spectrometry, XRD, FTIR, and TEM. According to TEM results, Pd nanoparticles were observed to have a spherical shape and an average particle size of 4.91 nm. The Pd NPs showed the photodegradation of MB solution by up to 79.9% at 120 min. The newly synthesized plant-mediated green synthesized Pd NPs showed the max and the min antimicrobial activity at 16 µg/mL and 256 µg/mL against L. pneumophila and C. albicans, respectively. The current density ratio of 48.22 mA/cm2 obtained in the study indicates that the obtained materials may be of interest in different applications. According to the results obtained, a direct relationship of extract use is observed in the synthesis of Pd nanoparticles and is a good way to reduce and stabilize metal salts. It has been determined that green Pd NPs have potential for use in energy production from alcohol oxidation and in medical applications.

A simple and efficient catalyst for Suzuki reaction based on ultra-low palladium chloride supported on ZnO nanowires

Zinc oxide nanowires were synthesized and impregnated with trace amounts of palladium ions by adsorption, which was then employed as a heterogeneous catalyst in the Suzuki reaction. To obtain an in-depth understanding of the structure and properties of the ZnO nanowires and the resultant catalyst, different analysis techniques were performed. The as-synthesized catalyst demonstrated exceptional efficiency in promoting the reaction between aryl halides and arylboronic acids, enabling the achievement of biphenyl derivatives in high yields ranging between 82% and 99%. The analysis conducted using transmission electron microscopy demonstrated the formation of palladium nanoparticles during the reaction, confirming their role as the active species driving the catalytic transformation. Further investigation was carried out to examine the effect of the support on the catalytic activity of the catalyst. The results indicated that the morphology and crystallographic structure of zinc oxide had a significant impact on the catalytic activity of the prepared catalyst. The catalytic performance of PdCl2/ZnONWs, where palladium chloride immobilized on ZnO nanowires, was found to be exceptional. The catalyst demonstrated the ability to be recovered and reused up to three times without a noticeable decline in its catalytic activity. Additionally, the loading of palladium species could be reduced to 7.6 mol part per million. Remarkably, the catalyst achieved a total turnover number of 130,000 and a turnover frequency of 0.75 s−1.

Palladium nanoparticle formation on boron nitride nanotubes and their photocatalytic performance with visible light

Development of efficient but long-term stable photocatalysts for removal of organic pollutants from water sources is still a huge challenge up to date. In this study, palladium nanoparticles (Pd NPs) were dispersed on the surface of boron nitride nanotube (BNNT), a series of Pd@BNNT hybrid was synthesized using a one-step and cost-effective ultrasonication method, and the photocatalytic performance were investigated. By increasing the ultrasonication time, productivity of the Pd NPs on BNNT was increased and also obtained the uniform nanostructure, thereby enhancing the specific surface area, which is the promising attribute for the efficient removal of organic pollutants. In this regard, the Pd@BNNT3 hybrid shows higher photocatalytic performance with respect to other catalysts against the crystal violet and levofloxacin, 97.6%/50 min, and 97.7%/40 min respectively. Further, a reusability test was conducted for the Pd@BNNT3 hybrid by using the CV over seven consecutive cycles. Approximately, 24.7% photocatalytic efficiency was lost in the final catalytic activity owing to its particle loss (7.2%). Significantly, the structure of the Pd@BNNT3 catalyst did not change even after measuring the reusability seven times, suggesting that the catalyst has a stable morphology. The enhanced photocatalytic performance is attributed to the larger specific surface area (128 m2/g) of Pd@BNNT3 hybrid, which enhance the production of the visible light induced radical oxygen species. As a summary, the efficient photocatalyst developed in this study can eliminating the organic contaminants from the wastewater source and is a highly promising solution for tackling wastewater treatment challenges in the near future.

Rosa damascena flower mediated phytofabrication of palladium nanoparticles, in-vitro and in-vivo applications

The formation of palladium nanoparticles is described in this research work as being simple, affordable, and non-toxic. This study employed Rosa damascena flower extract to effectively reduce ions to palladium nanoparticles. Biogenic formation of palladium nanoparticles (PdNPs) is characterized using Ultraviolet spectrophotometers, FTIR, XRD spectrophotometers, and TEM. The SPR peak was recorded at 360 nm in UV–visible analysis of biologically formed palladium nanoparticles. The diameter of the synthesized palladium nanoparticles was around approx 50 nm with a spherical shape. These biologically formed palladium nanoparticles demonstrated notable antibacterial activities. After antibacterial testing of palladium nanoparticles further check for anti-inflammatory and analgesic activity on rat model. These finding indicate that the flower extract of R.damascena is an excellent bio-reductant for the formation of palladium nanoparticles and has promise for employment in several fields in biomedical application.

Environmentally sustainable fabrication of palladium nanoparticles from the ethanolic crude extract of Oxystelma esculentum towards effective degradation of organic dye

Oxystelma esculentum plant is well-known for its broad spectrum of ayurvedic and conventional medicinal applications. The ethanolic crude extract of this plant was used to synthesize palladium nanoparticles in an environmentally friendly manner. The discreetness of the method adopted is the rapid sustainable fabrication of nanoparticles and the utilization of the nanoparticles for their effective catalytic activity. The systematic characterization of nanoparticles was done by standard analytical tools, UV–Vis spectroscopy, dynamic light scattering, zeta potential, atomic force microscopy, X-ray diffraction, and scanning electron microscopy. The appearance of sharp peak at 471 nm indicated the adequate formation of palladium nanoparticles. The morphology and topography of nanoparticles were obtained by SEM and AFM. The crystalline nature of nanoparticles was analyzed by X-ray diffraction. The effective catalytic activity against the toxic organic dye methylene blue in the presence of the reducing agent NaBH4. Recognition of products formed by the degradation of methylene blue was then carried out through electrospray ionization coupled mass spectrometry. Moreover, the calculated Pd loading in the nanocomposites was 0.2 mmol/g. Meanwhile, to better evaluate the characteristic role of active species in catalytic degradation, the quenching study by scavengers methanol, ammonium oxalate, p-benzoquinone, and triethanolamine was also performed. Furthermore, the catalyst showed stability and reusability towards the degradation of a pollutant, thus can be also explored for other emerging pollutants.

Green synthesis of Pd@biochar using the extract and biochar of corn-husk wastes for electrochemical Cr(VI) reduction in plating wastewater

In this study, Corn Husks, as an organic waste, were utilized to synthesize palladium nanoparticles (PdNPs) using a green approach and the related biochar as a support material for PdNPs to produce Pd@biochar nanocatalyst. Pd@biochar nanocatalysts were synthesized using the extracted liquid from corn husks and PdCl2 salt, and biochar was obtained by a hydrothermal process conducted on chapped corn husks. FESEM, UV-Vis, XRD, and FTIR were used to evaluate the physicochemical properties of the nanocatalyst and the formation of PdNPs using the implemented approach. The effect of the Pd@biochar mass ratio was explored, and nanocomposite with a mass of 0.06 palladium to biochar was the most favorable catalyst. The Design Expert software was applied to investigate and optimize the effect of parameters, such as pH, initial Cr(VI)concentration, and contact time, using the Response Surface Box Behnken method. The proposed model of Design Expert software indicated a 99.9% reduction of Cr(VI) at optimum conditions ( pH=1, initial Cr(VI) concentration= 100 mg L-1, contact time= 60 min). The kinetics of the electrochemical reaction showed a high correlation with the pseudo-first-order model at different concentrations of Cr(IV). The applicability of synthesized nanocatalyst in six cycles of the experiment was tested, and results pointed out only a 10% decrease in nanocatalyst efficiency, proving its high stability. The electrochemical reduction of Cr(VI) in real plating wastewater was investigated at optimum conditions, which resulted in a 99.7% reduction and 0.35 mg L-1 residual of Cr(IV), reaching Iran’s standard for industrisal wastewater discharge.

Synthesis of Pd nanoparticle and study the effect on Adenosine amino hydrolase (ADA) enzyme activity in blood serum

Chemical reduction with trisodium citrate as the reducing agent resulted in the successful formation of palladium nanoparticles (Pd NPs), and all of the material's components were synthesised in double-distilled water. UV-vis spectroscopy, X-ray diffraction, with Transmission Electron Microscopy were all utilised to investigate the Pd nanoparticles. According to TEM investigations, the average size of the Pd nanoparticles formed was 13.5 - 45 nm. Serum adenosine deaminase (ADA) activity in atherosclerosis patients was tested to see if Pd NPs had any effect. Serum ADA activity was considerably higher in individuals with atherosclerotic disease, both in those treated with Pd nanoparticles and in those who were not (P<0.01). Pd nanoparticles significantly lowered blood levels of ADA activity in atherosclerotic disease patients compared to those who did not receive Pd nanoparticles.

Biogenic Pd-nanoparticles from Lantana trifolia seeds extract: Synthesis, characterization, and catalytic reduction of textile dyes

In the present work, the microwave-assisted biogenic synthesis of Palladium Nanoparticles (PdNPs) employing different concentrations of Lantana trifolia seeds extract as a reducing and stabilizing agent in accordance with the concept of environmentally friendly approach. The synthesized PdNPs were characterized using several analytical techniques to examine their morphology, microstructure, crystallinity, optical, and surface functional modification properties. The formation of PdNPs in the reaction solution was evidenced by a visible black color and broad continuous absorption spectra in the UV–Vis absorption spectra. The FTIR spectra were revealed that the phytochemicals were interacted with Pd metal in nanoparticle formation. The prepared PdNPs have a spherical shape and polydispersity nature with an average size of particles is 10 ± 2 nm. In addition, the synthesized PdNPs were well stabilized (zeta potential = −25.5 ± 2.8 mV) by the phytochemicals in seed extract and a face-centered cubic crystal (FCC) structure. The biosynthesized PdNPs were further investigated as a nanocatalyst in the catalytic reduction of Crystal Violet (CV) and Methyl Orange (MO) dyes in the presence of NaBH4 at room temperature. For CV and MO dyes reduction, the homogenous catalytic performance of PdNPs resulted in practically > 98 % of reduction with kinetic rate constant values of 0.393 min−1 (10 min) and 0.232 min−1 (18 min), respectively. Moreover, there is no significant loss in catalytic activity was observed after recovery and reusability of the biosynthesized PdNPs.

Strategies for palladium nanoparticles formation on halloysite nanotubes and their performance in acetylene semi‑hydrogenation

Pd nanoparticles are widely applied in catalysis. In this work, the deposition of Pd nanoparticles onto halloysite (Hal) nanotubes from different Pd precursors and solvents has been investigated. The prepared Pd/Hal catalysts have been characterized by low-temperature N2 adsorption, transmission electron microscopy, zeta potential measurement, and tested in the hydrogenation of acetylene. On calcined Hal, the largest nanoparticles are formed in acid media, and the smallest are formed in non-aqueous one. Silanization of halloysite decreases absolute values of its zeta potential significantly and drops PdNPs size twice. Catalytic tests have shown that acetylene conversion and selectivity to ethylene depend on the deposition method, and the most active catalysts were prepared from Pd acetate dissolved in acetone. The lowest activity and highest selectivity to ethylene were demonstrated by the azine-modified halloysite, that could be related to Pd poisoning with nitrogen.

Synthesis and Catalytic Activity in the Hydrogenation Reaction of Palladium-Doped Metal-Organic Frameworks Based on Oxo-Centered Zirconium Complexes

Metal-nanocluster-doped porous composite materials are attracting considerable research attention, due to their specific catalytic performance. Here we report a simple, cheap, and efficient strategy for the preparation of palladium hydrogenation catalysts based on metal-organic frameworks (MOFs). It has been shown that the synthesis of Pd/MOF results in the formation of palladium nanoparticles uniformly fixed on the surface. The composition and structure of the resulting composites were studied using elemental analysis, DSC, TGA, XRD, TEM, and IR spectroscopy. Pd nanoparticles with an average diameter of 8–12 nm were successfully confined in the UiO-type MOFs, and the obtained nanocomposites exhibited abundant porosity, high stability, and a large surface area. It has been shown that the resulting catalytic systems with high activity, selectivity, and stability reduce phenylacetylene and allyl alcohol to styrene and propanol, respectively, in liquid-phase hydrogenation reactions.

A rare example of the in situ formation of palladium nanoparticles: The emergence of catalytically active palladium nanoparticles from Pd (II) phosphine complexes in the Suzuki–Miyaura coupling reaction

Suzuki–Miyaura coupling (SMC) reactions are one of the most promising routes for carbon–carbon bond formation. It is believed that metal complexes, particularly palladium complexes, are the most effective catalysts for this purpose. However, the catalysis nature whether it is homogenous or heterogeneous is under debate. It is commonly believed that a homogenous catalysis pathway is responsible for the catalytic activity when the phosphine ligands are present in the structure due to the strong phosphorus‐metal interactions. In this study, Pd (II) complexes of phosphino‐benzaldoxime ligands were synthesized, characterized, and tested in SMC reactions. Interestingly, it was found that the catalytic activity increased by 11 times when the amount of catalyst was reduced by 10‐fold and increased by five times when the amount of catalyst was decreased by 100‐fold. The detailed analyses revealed that the palladium nanoparticles (NPs) are responsible for the catalytic activity which was formed in the reaction medium. A plausible mechanism was proposed for the formation of Pd NPs from palladium phosphino‐benzaldoxime complexes in the reaction medium. This study is expected to contribute to the debate over whether the catalytic activity of phosphine‐palladium complexes in SMC reactions results from a homogeneous or heterogeneous pathway.

Recyclable Pd‐based polysaccharide catalyst for aerobic oxidation of benzyl alcohol

AbstractPalladium acetate that was heterogenized together with triphenylphosphine trisulfonate ligand on renewable polysaccharides was employed in the aerobic oxidation of benzyl alcohol in three representative solvents—hexane, ethyl acetate, and ethanol. Solvent polarity was found to affect the reaction rate, as both the solubility of benzyl alcohol and oxygen depend on the nature of the solvent. The conversion rate was decreased in the order of hexane > ethanol > ethyl acetate (conversion rates in the presence of the heterogenized iota‐based catalyst after 24 h of reaction were 38, 20, and 15%, respectively). In addition, the nature of the polysaccharide, that is, the type and numbers of functional groups on its backbone, also affected the reaction rate, where xanthan gum yielded the highest conversion rate of 58% in hexane. Finally, though hexane was found to be the preferred solvent for the heterogeneous system, catalytic performance in hexane decreased during recycling while in ethanol it increased due to the formation of palladium nanoparticles. To reveal the structural changes undergone by the catalyst during the reaction, several techniques were used, including energy dispersive X‐ray spectrometry‐scanning electronic microscopy, X‐ray photoelectron spectroscopy, Transition electronic microscopy, and thermal gravimetric analysis. This simple and straightforward heterogenization procedure can be also used for immobilization of different other metal complexes in variety of organic reactions.

The in-situ XAS study on the formation of Pd nanoparticles via thermal decomposition of palladium (II) acetate in hydroxyl functionalized ionic liquids

The formation of palladium nanoparticles (NPs) via thermal decomposition of palladium (II) acetate in hydroxyl functionalized ionic liquid (IL) [C2OHmim]+[NTf2]− was studied using in-situ energy dispersive x-ray absorption fine structure spectroscopy (DXAFS) and complementary methods such as transmission electron microscopy (TEM) and inductively coupled plasma mass spectrometry. Detailed XAFS spectra analysis unraveled that the palladium acetate trimer precursor underwent dissociation after being dispersed in ILs, which accelerated the thermal decomposition compared with other organic solvents. Based on the reaction kinetics, extened x-ray absorption fine structure spectroscopy fitting and TEM characterization results, the thermal decomposition process can be divided three successive stages namely the explosive nucleation, autocatalytic surface growth and NP attachment growth.

Sterically Hindered Phosphonium Salts: Structure, Properties and Palladium Nanoparticle Stabilization.

A new family of sterically hindered alkyl(tri-tert-butyl) phosphonium salts (n-CnH2n+1 with n = 2, 4, 6, 8, 10, 12, 14, 16, 18, 20) was synthesized and evaluated as stabilizers for the formation of palladium nanoparticles (PdNPs), and the prepared PdNPs, stabilized by a series of phosphonium salts, were applied as catalysts of the Suzuki cross-coupling reaction. All investigated phosphonium salts were found to be excellent stabilizers of metal nanoparticles of small catalytically active size with a narrow size distribution. In addition, palladium nanoparticles exhibited exceptional stability: the presence of phosphonium salts prevented agglomeration and precipitation during the catalytic reaction.

Photolysis of Solutions of Palladium(II) Complex Compounds with Organic Acids

Palladium nanoparticles were obtained by the photochemical reduction of the palladium(II) complex compounds K2[Pd(C2O4)2], [Pd(Gly)2], and [Pd(β-Ala)2] in a photolyte volume. The highest rate of formation of palladium nanoparticles in the photolyte volume is observed during the photolysis of the K2[Pd(C2O4)2] complex and the lowest—in the case of the [Pd(β-Ala)2] complex. Palladium particles obtained by the photolysis of aqueous solutions of the [Pd(β-Ala)2] and [Pd(Gly)2] complexes have the highest storage stability even in the absence of a stabilizer. When calcined in air in the presence of palladium nanocomposite particles on a CeO2 carrier, the temperature of the oxidation beginning decreases, and the weight loss of the sample (soot) increases.

Microwave-assisted synthesis of palladium nanoparticles using Frankincense resin and evaluation of their catalytic properties

The present study describes a microwave-assisted synthesis of well-dispersed palladium nanoparticles (PdNPs). For the first time,Frankincense resin (FR) obtained from the tree of Boswellia sacra is explored for the preparation of PdNPs. This method is rapid, inexpensive and devoid of toxic chemicals. FR aqueous extract with reducing polysaccharides and other phytochemicals served as an effective reducing and stabilizing agent for PdNPs. Formation of PdNPs was preliminarily confirmed by UV–visible and mechanism of formation was proposed from Fourier transform infrared spectroscopy. Transmission electron microscopic images displayed spherical PdNPs with an average size of 11 ± 2 nm. Catalytic activity studies revealed that the PdNPs act as an efficient catalyst for the reduction of both cationic (Methylene Blue) and anionic (Congo red) dye pollutants. Moreover, the PdNPs can be recovered and reused for five cycles without a significant loss in their catalytic activity.

Microwave-assisted One-pot Synthesis of 2-Substituted Quinolines by Using Palladium Nanoparticles as a Catalyst developed from Green Alga Botryococcus braunii

Background:Quinoline is a type of N-based organic heterocyclic biologically active compound. Quinolines have grasped the interest of scientists because of their wide scope of applications. Several methods have been developed for the synthesis of quinoline and its derivatives. In this study, a new, efficient, simple, one-pot synthesis of the substituted quinolines was developed by using palladium nanoparticles as a catalyst.Methods:Catalyst synthesized by algal extract of green alga Botryococcus braunii and palladium acetate solution, and characterized by different instrumental techniques like FTIR, SEM, and XRD. The synthesized palladium nanoparticles explored for the catalytic activity in the synthesis of quinoline derivatives by the use of 2-aminobenzyl alcohol in toluene with acetyl derivatives followed by the addition of potassium hydroxide. The formation of the product was confirmed by 1HNMR, 13C NMR, and electron ionization mass spectra.Results:The formation of palladium nanoparticles characterized by visual observation means the color change from light pale yellow to dark brown indicates the reduction of palladium ions into palladium nanoparticles. Synthesized palladium nanoparticles characterized by FTIR spectrum of the algal extract of green algae B. braunii for the presence of proteins, lipids, carbohydrates, carotenoids, vitamins and other secondary metabolites in algal extract, which function as active components for bioreduction. The morphology of the catalyst was confirmed by SEM and X-ray diffraction measurements for shape, crystalline nature and size. The synthesized palladium nanoparticles explored for the catalytic activity in the synthesis of quinoline derivatives by use of 2-aminobenzyl alcohol in toluene and added acetyl derivatives followed by the addition of potassium hydroxide. In order to establish the optimum heating method, a comparative study between conventional and microwave heating method was carried out in the presence of palladium nanoparticles as a catalyst.Conclusion:This protocol provides a convenient and practical procedure for the preparation of quinoline derivatives from 2-aminobenzyl alcohol, acetyl derivatives, potassium hydroxide and palladium nanoparticles as a catalyst. This protocol will be helpful in synthesizing other quinoline derivatives and several organic heterocycles which are used in different fields such as biological, industrial, pharmaceutical, chemical, medical, etc.

Biochemical synthesis of palladium nanoparticles: The influence of chemical fixatives used in electron microscopy on nanoparticle formation and catalytic performance

Palladium nanoparticles (PdNPs) can catalyse a range of reductive chemical reactions transforming both organic and inorganic environmental pollutants. PdNPs that ranged from <2 to 2–40 nm were synthesized using chemical methods, and bacterial biomass with/without chemical fixatives. PdNP formation was enhanced by adsorption of Pd(II) to bacterial biomass, followed by fixation with formate or glutaraldehyde. TEM-SAED analyses confirmed that the cell associated PdNPs were polycrystalline with a face-centered cubic structure. Chemically formed PdNPs possessed a higher Pd(0):Pd(II) ratio and produced structurally similar nanoparticles as the biotic systems. These PdNPs were employed to catalyze two, reductive chemical reactions, transforming 4-nitrophenol (4-NP) and hexavalent chromium [Cr(VI)], into 4-aminophenol and Cr(IV), respectively. In the reduction of 4-NP, the catalytic performance was directly proportional to PdNP surface area, i.e., the smallest PdNPs in formate-PdCH34 cells had the fastest rate of reaction. The mass of Pd(0) as PdNPs was the main contributor to Cr(VI) reduction; the chemically synthesized PdNPs showed the highest removal efficiency with 96% at 20 min. The use of glutaraldehyde enhanced the reduction of Pd(II) and promoted PdNPs formation, i.e., creating an artefact of fixation; however, this treatment also enhanced the catalytic performance of these PdNPs.

Bio-inspired synthesis of catalytically and biologically active palladium nanoparticles using Bos taurus urine

Physiologically processed bio-molecules present in cow excreta can be used to reduce metal ions into metal nanoparticles in a single step by novel synthetic routes. This biogenic reduction of metal ion to base metal is quite rapid and easily scaled up. These NPs exhibit excellent catalytic activities for studied organic reactions. X-ray diffraction pattern of reaction product confirmed the formation of palladium nanoparticles. The synthesized PdNPs shows potential activity for organic transformation. Antimicrobial activity of nanoparticles determines biogenic potential of the nanoparticles against different microorganisms and antioxidant activity determined the potential of free radicals. Both of the antimicrobial and antioxidant activity helps in study application of nanoparticles in medical and veterinary sciences.