Abstract Background Civic participation has been associated with better self-reported health (SRH). However, how does the association between civic participation and SRH vary by sex and migration status? This study aims to examine the association between social and political determinants of health and SRH in an intersectional perspective. Methods We use data from 26 countries in the 2022 EU Statistics on Income and Living Conditions (EU-SILC) (n = 425,178, 18-80 y.o.), following an intercategorical approach. Eight intersectional groups are created based on sex, migration status and being socially/politically active (participation in activities related to active citizenship or in formal/informal voluntary activities). Multilevel (ML) logistic regression models are employed to assess the association between these groups and SRH, controlling for age and educational level. Results 24.6% of the sample indicate to be socially or politically active, with significant differences between sexes and migration status. A higher proportion of non-migrant active men report good SRH compared to the other intersectional groups (95.2%). Preliminary results from the ML logistic models show that being active increases the likelihood of good SRH (OR = 1.77, 95% CI 1.72-1.83). Migrant active women report better SRH than their non-active counterparts (OR = 1.27, 95% CI 1.12-1.44). Conclusions Findings suggest that being socially/politically active has a positive impact on SRH, especially among foreign women living in European countries. The study highlights the importance of considering civic (both political and social) participation as health determinant and the need of investing in social capital as a way of health promotion, tackling health inequalities and the marginalisation of at-risk groups. Key messages • Civic participation might strengthen individuals’ health, including among migrant women. • Public health policies should consider civic participation as significant determinant of individuals’ health, as well as a way of tackling health inequalities.