Skin diseases are among the most prevalent health concerns worldwide, affecting billions. Foot corns, also known as clavus, are a significant issue within this category. These thickened skin lesions, marked by a cone-shaped keratin core, arise from repetitive friction or pressure, often due to poor-quality or ill-fitting footwear. Women are disproportionately affected, largely because of specific footwear choices. Corns and calluses, although similar, have distinct features and locations, both causing discomfort and leading many to seek podiatric care. Foot corns affect 14% to 48% of the population, underscoring the need for effective treatments. Transdermal drug delivery systems have emerged as a promising solution, offering controlled, targeted medication delivery through self-contained patches, which minimizes systemic side effects. Recent research indicates the potential of combining natural remedies such as turmeric, neem, aloe vera, and tea tree oil with Transdermal drug delivery system for treating foot corns. These natural ingredients, known for their therapeutic properties, enhance treatment outcomes when used with advanced drug delivery technology. This combination not only increases the effectiveness of managing foot corn but also improves the quality of life for affected individuals. The success of the Transdermal drug delivery system in treating foot corns highlights the need for further research to optimize these systems and ensure their accessibility. For individuals with chronic foot issues, where traditional treatments may be inadequate, Transdermal drug delivery combined with natural remedies represents a significant advancement. This innovative approach offers a more effective and practical solution for managing foot corns and other skin conditions, providing hope and relief to millions worldwide.
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