This study presents an investigation into the application of predictive models based on Machine Learning to optimize sports betting strategies in football. The research was conducted using a combination of quantitative and qualitative methods, including the analysis of historical football match data and the implementation of machine learning algorithms. The results indicate that predictive models can be effective in forecasting football match outcomes, which can be useful for optimizing sports betting strategies. The practical application of these models can provide bettors with a competitive advantage, allowing them to make more informed decisions and potentially improve their financial outcomes. It is concluded that while predictive models offer a valuable tool for enhancing betting strategies, a careful approach and ongoing evaluation of the models are essential to maximize their effectiveness. The research suggests that future investigations could explore the integration of additional data and the improvement of algorithms to increase prediction accuracy.