Levels Of Food Restriction Research Articles

Perubahan Panjang Badan, Tinggi Pinggul Dan Tinggi Pundak Kambing Kacang Jantan Yang Mengalami Tingkat Pembatasan Pakan Yang Berbeda

This study aims to determine the increase in body length, hip height and shoulder height of Kacang goat at different levels of food restriction. The research was carried out in the goat pen of the Agriculture Faculty, Timor University from June until September 2022. The cattle used were 15 male Kacang goats with an average body weight of 10-15 kilograms (kg). This study used a Completely Randomized Design (CRD) experiment methode consisting of 3 treatments and 5 replications. The treatments used in this study were: T0 = Cattle without being restricted by feed, T1 = Cattle being limited by feed (100%) of maintenance life, T2 = Cattle being limited by feed (50%) of maintenance life. The variables observed in this study were body length, hip height and shoulder height. The data analyzed by using Analysis of Variance (Anova) and Duncan's multiple range test. The results showed that the average change in body length of male Kacang goat in the T0, T1, and T2 treatments was 0.040; -0.050; and -0.060 cm/head/day, respectively. Shoulder height of 0.060; -0.080; and -0.083 cm/head/day, respectively. Hip height of 0.087; -0.090; and -0.10 cm/head/day, respectively. Statistical analysis showed that the treatment had a significant effect on body length, shoulder height and hip height of male kacang goats (P<0.05). It was concluded that the T0 treatment without being restricted by feed gave the best results on changes in body length, shoulder height, and hip height in male Kacang goat.

Food Restriction Level and Reinforcement Schedule Differentially Influence Behavior during Acquisition and Devaluation Procedures in Mice.

Behavioral strategies are often classified based on whether reinforcer value controls reinforcement. Value-sensitive behaviors, in which animals update their actions when reinforcer value is changed, are classified as goal-directed; conversely, value-insensitive actions, where behavior remains consistent when the reinforcer is removed or devalued, are considered habitual. Basic reinforcement schedules can help to bias behavior toward either process: random ratio (RR) schedules are thought to promote the formation of goal-directed behaviors while random intervals (RIs) promote habitual control. However, how the schedule-specific features of these tasks interact with other factors that influence learning to control behavior has not been well characterized. Using male and female mice, we asked how distinct food restriction levels, a strategy often used to increase task engagement, interact with RR and RI schedules to control performance during task acquisition and devaluation procedures. We determined that food restriction level has a stronger effect on the behavior of mice following RR schedules compared with RI schedules, and that it promotes a decrease in response rate during devaluation procedures that is best explained by the effects of extinction rather than devaluation. Surprisingly, food restriction accelerated the decrease in response rates observed following devaluation across sequential extinction sessions, but not within a single session. Our results support the idea that the relationships between schedules and behavioral control strategies are not clear-cut and suggest that an animal's engagement in a task must be accounted for, together with the structure of reinforcement schedules, to appropriately interpret the cognitive underpinnings of behavior.

The impact of food restriction on liver enzyme levels: a systematic review and meta-analysis.

The relationship between food restriction (FR) and liver enzyme levels, such as alanine transferase (ALT), aspartate transferase (AST), and γ-glutamyl transferase (GGT), has not yet been confirmed. A meta-analysis of research articles was conducted to investigate the association of FR and liver enzyme levels. The PubMed, Web of Science, Embase, and Cochrane Library databases were screened for articles published up to April 30, 2022. Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement methodology was used to search for research articles. Publication bias was detected using Begg's test. Finally, 17 trials involving 1982 participants and that reported mean value, mean difference, and standard deviation were identified. Data were described as the weighted mean difference of body mass index, body weight, and standardized mean difference (SMD) of ALT, AST, and GGT. A reduction in ALT level was observed after a FR intervention (total SMD, -0.36, 95% confidence interval [CI], -0.68 to -0.05). GGT levels also were decreased in 4 studies (total SMD, -0.23; 95%CI, -0.33 to -0.14). According to subgroup analysis, serum AST levels decreased in the medium-term (between 5 wk and 6 mo) group (subtotal SMD, -0.48; 95%CI, -0.69 to -0.28). Existing evidence suggests that dietary restriction improves adult liver enzyme levels. The long-term maintenance of healthy liver enzyme levels, particularly in real-world applications, necessitates additional consideration.

Daphnia magna Gut‐Specific Transcriptomic Responses to Feeding Inhibiting Chemicals and Food Limitation

Transcriptomic responses combined with apical adverse ecologically relevant outcomes have proven to be useful to unravel and anchor molecular mechanisms of action to adverse outcomes. This is the case for feeding inhibition responses in the model ecotoxicological species Daphnia magna. The aim of this study was to assess the transcriptomic responses in guts dissected from D. magna individuals exposed to concentrations of selected compounds that inhibit feeding, and compare them with the responses associated to two levels of food restriction (low food and starvation). Chemical treatments included cadmium (Cd), copper (Cu), fluoranthene, λ-cyalothrine and the cyanotoxin anatoxin a. While the initial hypothesis was that exposure to chemical feeding inhibitors should elicit similar molecular responses as food limitation, the corresponding gut transcriptomic responses differed significantly. At moderate food limitation conditions, D. magna individuals increased protein and carbohydrate catabolism, likely to be used as energetic sources, whereas under severe starving conditions most metabolism-related pathways appeared down-regulated. Treatment with chemical feeding inhibitors promoted cell turnover-related signalling pathways in the gut, probably to renew tissue damage caused by the reported oxidative stress effects of these compounds, and inhibited the transcription of gut digestive gene- enzymes and energetic metabolic pathways. We conclude that chemical feeding inhibitors, rather than mimetizing the physiological response to low- or no-food conditions, cause specific toxic effects preventing Daphnia both from feeding and from adjusting its metabolism to the resulting low energy intake. This article is protected by copyright. All rights reserved.

Compensatory growth in Nile tilapia Oreochromis niloticus: feed conversion ratio, size heterogeneity, and proximal composition

A feeding test was performed to evaluate compensatory growth in the Nile tilapia (Oreochromis niloticus) and to assess changes in feed conversion ratio (FCR), body condition, and carcass composition associated with the imposed feeding strategy. The experiment was carried out under two different stages, restricted (RS) and compensated (CS), with six weeks long each other. Three hundred juveniles of Nile tilapia (average weight of 16.4 ± 0.2 g) were divided into three treatments and one control. The control group was fed to apparent satiation four times a day in both stages. The RS treatments were based on 100% (RS100), 80% (RS80), and 60% (RS60) of a feeding chart, respectively. In the next six weeks, fishes from the CS treatments (CS100, CS80, and CS60) were then fed to apparent satiation four times a day. In the RS, the control group displayed the most considerable weight gained, but with a significant FCR. Nevertheless, in the CS, the previous restricted treatments (RC80 and RC100) showed a compensatory growth, with a smaller FCR than the control group. The restricted-compensated rations did not have a significant effect on the size heterogeneity; when the food is restricted, fish use to moisturize their tissue to compensate for the muscle loss until they receive more food. However, when the food restriction levels are too high, the weight gain, lipid, and protein levels do not recover as they were before. Thus, restricted (marginally) and compensatory feeding strategies provide evidence that growth rates of fishes can be regulated.

Increasing Energy Flux to Maintain Diet-Induced Weight Loss.

Long-term maintenance of weight loss requires sustained energy balance at the reduced body weight. This could be attained by coupling low total daily energy intake (TDEI) with low total daily energy expenditure (TDEE; low energy flux), or by pairing high TDEI with high TDEE (high energy flux). Within an environment characterized by high energy dense food and a lack of need for movement, it may be particularly difficult for weight-reduced individuals to maintain energy balance in a low flux state. Most of these individuals will increase body mass due to an inability to sustain the necessary level of food restriction. This increase in TDEI may lead to the re-establishment of high energy flux at or near the original body weight. We propose that following weight loss, increasing physical activity can effectively re-establish a state of high energy flux without significant weight regain. Although the effect of extremely high levels of physical activity on TDEE may be constrained by compensatory reductions in non-activity energy expenditure, moderate increases following weight loss may elevate energy flux and encourage physiological adaptations favorable to weight loss maintenance, including better appetite regulation. It may be time to recognize that few individuals are able to re-establish energy balance at a lower body weight without permanent increases in physical activity. Accordingly, there is an urgent need for more research to better understand the role of energy flux in long-term weight maintenance.

Augmentation of morphine-conditioned place preference by food restriction is associated with alterations in the oxytocin/oxytocin receptor in rat models

ABSTRACT Background Studies indicate that food restriction (FR) reinforces the effects of morphine. The exact mechanisms by which FR influences the reward circuitry of morphine have not yet been determined. Objectives We hypothesized that the effects of FR on the oxytocin (OXT) system and HPA axis can be associated with substance abuse disorders. In this study, the serum levels of OXT and corticosterone, and the expression of OXT/OXT receptor (OXTR), glucocorticoid receptor (GR), and brain-derived neurotrophic factor (BDNF) in the hippocampus, prefrontal cortex, and nucleus accumbens were investigated in an FR model. Methods First, the male rats (n = 8 per group) were subjected to FR for 3 weeks. Then, morphine-induced conditioned place preference (CPP) was observed using two doses of morphine (3 and 5 mg/kg). The serum concentrations of corticosterone and OXT were determined by ELISA and the expression of genes was examined by qPCR. Results FR induced an enhanced preference in the animals for the 5 mg/kg dose of morphine compared to the controls. Serum corticosterone levels increased after FR but OXT levels decreased. Meanwhile, FR actuated downregulation of GR, BDNF, and OXT genes, while inducing the overexpression of OXTR. Conclusion We propose the inclusion of OXT and OXTR alterations in the enhancement of morphine-induced CPP and addiction vulnerability following FR. Moreover, we conclude that altered BDNF levels and HPA axis activity may be the mechanisms involved in the effects of FR on morphine-induced behavior.

Effects of food restriction on energy metabolism in male Apodemus chevrieri from Hengduan mountain region of China

To investigate the relationship between the energy strategies in response to food restriction and the levels of metabolism in small mammals, body mass, resting metabolic rate (RMR), nonshivering thermogenesis (NST) and cytochrome c oxidase (COX) activity were measured in Apodemus chevrieri that were subjected to different levels of food restriction (FR). The results showed that cold-exposed group had significantly increased RMR and NST, but decreased body mass and survival rate after being restricted to 80% of ad libitum food intake compared with their counterparts maintained at room temperature. A. chevrieri with higher RMR consumed higher food intake than individuals with lower RMR, whereas no differences were observed in body mass and survival rate between two groups after being restricted to 80% of ad libitum food intake. The results suggest that A. chevrieri characterized by higher levels of metabolism are sensitive to periods of FR, providing a support for the “metabolism switch hypothesis”.

Energy and protein requirements for maintenance of Texel lambs

It can be hypothesized that the body composition characteristics of different sheep breeds affect their nutritional requirements. However, no study has yet been carried out to determine the nutritional requirements for maintenance of Texel purebred lambs, despite their growing importance in sheep meat production globally. Our objective was therefore to determine the energy and protein requirements for maintenance of Texel lambs. Thirty-four Texel lambs were used, all intact males that were weaned at 50 days old, and confined in individual pens. Two experiments were conducted, as follows. In Experiment 1, a digestibility assay was performed to determine the dietary energy value, in a 3×3 double Latin square design, in which lambs were submitted to three levels of feed restriction (0%, 55% and 70% of ad libitum feed intake). In Experiment 2, the energy and protein requirements for maintenance of Texel lambs from 21 to 40 kg BW were determined using a randomized block design, in which lambs were also submitted to three levels of feed restriction (0%, 55% and 70% of ad libitum feed intake). The requirements for net energy for maintenance (NEm), metabolizable energy for maintenance (MEm), net protein for maintenance (NPm) and metabolizable protein for maintenance (MPm) were determined. The digestibility of dry matter, energy, protein and metabolizability were similar between food restriction levels, averaging 74.4%, 75.5%, 80.3% and 0.636, respectively. The NEm determined for growing Texel lambs was 263 kJ/kg of the metabolic fasting BW (FBW), the MEm was 417 kJ/kg0.75 FBW and the efficiency of use of MEm was 0.63. In addition, the NPm was 1.24 g/day per kg0.75 FBW and the MPm was 2.98 g/day per kg0.75 FBW. The energy requirements of Texel lambs are different from those reported in the literature, possibly due to differences between breeds, diets and environmental effects, whereas the protein requirements are different from literature mainly due to methodological differences; further studies are need to address these aspects that affects the nutritional requirements for raising sheep from different breeds in different environments.

PERFIL METABÓLICO DE CORDEIROS SANTA INÊS TERMINADOS EM CONFINAMENTO COM MANEJO ALIMENTAR RESTRITIVO E AD LIBITUM

Resumo Objetivou-se avaliar o perfil metabólico de 24 ovinos Santa Inês, machos, com peso vivo médio inicial de 20±1,25 kg, submetidos à restrição alimentar seguida de realimentação em confinamento, distribuídos em quatro tratamentos com 0, 20, 40 ou 60% de restrição alimentar. Dois ensaios foram desenvolvidos, um referente à restrição e outro à realimentação. Para tanto, foi utilizado delineamento experimental inteiramente ao acaso, com quatro tratamentos e seis repetições. Observou-se na fase de restrição alimentar que houve um decréscimo linear para as concentrações bioquímicas de ureia, glicose, GGT e fósforo; contrariamente, a concentração de colesterol aumentou linearmente ao final do período restritivo. A restrição alimentar influenciou negativamente nas concentrações de triglicerídeos e creatinina, diferentemente, os valores de proteínas totais e albumina apresentaram aumento significativo com o período restritivo. Já na realimentação, observou-se comportamento linear decrescente para ureia, glicose, GGT e magnésio. No segundo ensaio, verificou-se que as concentrações de proteínas totais, globulina e creatinina apresentaram diferença (P<0,05) entre os períodos de coleta. Os níveis de restrição alimentar afetaram o metabolismo proteico e interferiram também no metabolismo energético e mineral e a realimentação resultou em alteração no metabolismo proteico e energético.

Maternal Programming of Body Weight in Syrian Hamsters.

Maternal programming of offspring energy balance has been viewed as an adaptation in which the gestational environment prepares the offspring to thrive and reproduce in that same postnatal environment. Programming might have the opposite effect, however, when gestational and postnatal environments are mismatched. Gestational programming would represent a trade-off if the mother can maximize fitness in one possible energetic future but cannot maximize fitness in another. The vast majority of research concerns rats, mice, or sheep, and dams are typically food restricted by 30-70% of ad libitum intake resulting in low birth weight and adult obesity in offspring. Few previous studies have used a lower level of food restriction, and no experiments, to the best of our knowledge, were designed to determine whether the effects of gestational restriction have postgestational effects independent of the effects that occurred during gestation. In the present experiment, Syrian hamsters were either restricted to 90% of their ad libitum food intake or fed ad libitum during pregnancy. All litters were cross-fostered at birth and all were fed ad libitum during lactation. Half of the litters from ad libitum-fed pregnant dams were fostered to dams that had been food restricted during pregnancy and half of the litters from food-restricted pregnant dams were fostered to ad libitum-fed dams. The latter group allowed us to test the hypothesis that the effects of having a gestationally food-restricted mother affects offspring characteristics independent of the prenatal programming. First, we found significant increases in the postnatal body weight of the offspring of ad libitum-fed mothers fostered to food-restricted dams, supporting the hypothesis that the effects of gestational restriction carry over to postnatal maternal ability (e.g., milk yield, milk content, or parental behavior). Second, the carry-over effects of gestational food restriction on offspring postnatal body weight were significant in male but not female offspring. This occurred even though this group had significantly lower food intake than offspring of ad libitum-fed mothers with ad libitum-fed foster mothers. In addition, and contrary to expectation, gestational food restriction had no significant effect on adult baseline food hoarding or food hoarding in response to food restriction. These results suggest that even mild energetic challenges during gestation can have postgestational effects on maternal ability, and the effects on offspring are sex-specific.

RFamide-related Peptide-3 and the Trade-off between Reproductive and Ingestive Behavior.

SynopsisIngestive and sex behaviors are important for individual survival and reproductive success, but when environmental energy availability is limited, individuals of many different species make a trade-off, forfeiting sex for ingestive behavior. For example, food-deprived female Syrian hamsters (Mesocricetus auratus) forego vaginal scent marking and lordosis (sex behaviors) in favor of foraging, hoarding, and eating food (ingestive behavior). Reproductive processes tend to be energetically costly, and individual survival requires homeostasis in metabolic energy. Thus, during energetic challenges, the chances of survival are enhanced by decreasing the energy expended on reproductive processes. The entire hypothalamic-pituitary-gonadal (HPG) system is inhibited by severe energetic challenges, but comparatively little is known about the effects of mild energetic challenges. We hypothesized that (1) a trade-off is made between sex and ingestive behavior even when the level of food restriction is insufficient to inhibit the HPG system; (2) mild energetic challenges force a trade-off between appetitive ingestive and sex behaviors, but not consummatory versions of the same behaviors; and (3) the trade-off is orchestrated by ovarian steroid modulation of RFamide-related peptide 3 (RFRP-3). In other species, RFRP-3, an ortholog of avian gonadotropin-inhibitory hormone, is implicated in control of behavior in response to energetic challenges and stressful stimuli. In support of our three hypotheses, there is a “dose-response” effect of food restriction and re-feeding on the activation of RFRP-3-immunoreactive cells in the dorsomedial hypothalamus and on appetitive behaviors (food hoarding and sexual motivation), but not on consummatory behaviors (food intake and lordosis), with no significant effect on circulating levels of estradiol or progesterone. The effect of food restriction on the activation of RFRP-3 cells is modulated at the time of estrus in gonadally-intact females and in ovariectomized females treated with progesterone alone or with estradiol plus progesterone. Intracerebral treatment with RFRP-3 results in significant decreases in sexual motivation and results in significant but small increases in food hoarding in hamsters fed ad libitum. These and other results are consistent with the idea that ovarian steroids and RFRP-3 are part of a system that orchestrates trade-offs in appetitive behaviors in environments where energy availability fluctuates.

Obesity and malnutrition similarly alter the renin–angiotensin system and inflammation in mice and human adipose

The main goal of the present study was to evaluate the metabolic profile, inflammatory markers and the gene expression of the renin–angiotensin system (RAS) components in the visceral adipose tissue of eutrophic, obese and malnourished individuals and mice models of obesity and food restriction. Male Swiss mice were divided into eight groups and fed different levels of food restriction (20%, 40%, or 60%) using standard or high-fat diet. Metabolic profile and adipose tissues were assessed. The expression of AGT (Angiotensinogen), ACE (Angiotensin-converting enzyme), ACE2 (Angiotensin-converting enzyme 2), interleukin-6 (IL-6) and tumor necrosis factor-alpha (TNF-α) in the mice epididymal adipose tissue and the human visceral adipose tissue was assessed. The main findings showed reduced body weight, improved metabolism, decreased adipose tissues weight and reduced adipocyte area in mice submitted to food restriction. Diminished expression of IL-6, TNF-α, AGT, AT1 and ACE was detected in the 20% and 40% food restriction animal groups, although they were increased in the 60% malnourished group. Increased expression of IL-6, TNF-α, AGT and ACE in obese and malnourished individuals was observed. Adipocytes size was increased in obese individuals and reduced in malnutrition. In conclusion, we found that food restriction of 20% and 40% improved the metabolic profile, ameliorated the inflammatory status and down-regulated the RAS in mice. Severe 60% food restriction (malnutrition), however, stimulated a proinflammatory state and increased AGT and ACE expression in the adipose tissue of mice. A similar profile was observed in the adipose tissue of obese and malnourished humans, supporting the critical role of inflammation and RAS as mediators of metabolic disorders.

An Exploration of How Family Dinners Are Served and How Service Style Is Associated With Dietary and Weight Outcomes in Children

ObjectiveTo explore how families serve meals and how different service styles are associated with responsive feeding and child dietary and weight outcomes. MethodsBaseline data from a subset (n = 75) of randomized controlled trial participants (Healthy Home Offerings via the Mealtime Environment (HOME) Plus study, aged 8–12 years) were analyzed using a series of linear regression models. Adjusted means (95% confidence intervals) and beta coefficients (SEs) are presented. ResultsFamilies were most likely to report plated meal service (36% of families), followed by family-style (29%). Family-style was significantly associated with a lower mean level of food restriction (P = .01). No significant associations were observed between style of meal service and child outcomes (all P > .05). Conclusions and ImplicationsAlthough plated meal service may seem like a desirable strategy for ensuring that children eat a healthier diet, the current results did not provide support for this association. Evidence was found to support the use of family-style meal service to promote the use of responsive feeding.

Meat quality of castrated and non-castrated Santa Ines lambs subjected to food restriction

This study aimed to evaluate the quality of meat of castrated and non-castrated Santa Ines lambs submitted to food restriction. Were used 30 lambs, 15 castrated and 15 non-castrated, about two months of age and average initial body weight of 13.00 ± 1.49 kg. The lambs were distributed in a completely randomized design in a factorial arrangement 3 x 2 (restriction level x sex class), according to the amount of food provided. The duration of the experiment was determined by the time required for the animals in the one of the groups achieved 28 kg of body weight. There was interaction between food restriction levels and sex class to the variables intensity of yellow color and pH in the longissimus lumborum muscle and the shear force in the semimembranosus muscle. In non-castrated animals, the intensity of yellow color was higher in the longissimus lumborum muscle at the level of 30% of food restriction. There was no significant interaction between food restriction levels and sex class for the quality aspects related to color saturation, color tone, luminosity, red intensity, water holding capacity and cooking losses in longissimus lumborum and semimembranosus muscles. Although food restriction and sex class have influenced the variables related to the quality of meat of the animals evaluated, the mean values are considered acceptable by the literature. The feeding restriction levels and sex class influence some important features of quality of Santa Ines lamb meat.

Carcass and non-carcass components of Santa Ines lambs subjected to food restriction

The objective of this study was to evaluate the effect of sex class (castrated; non-castrated) and level of food restriction (0%, 30% and 60% of ad libitum consumption) on the quantitative composition of carcass and non-carcass components of Santa Ines lambs. A completely randomized 3x2 design (restriction level x sex class) was used to evaluate thirty lambs approximately two months of age with an average initial body weight of 13 ± 1.49 kg. When the average body weight of the animals in one of the treatment groups reached 28 kg, all animals were slaughtered. Sex class had effect on body weight at slaughter, empty body weight, hot carcass weight and cold carcass weight. The weight of the leg was greater in non-castrated animals. There was linear decreased effect according to increasing levels of restriction for the carcass cuts, except for leg and rear loin yield. There was statistic difference between sex class for the weights of kidneys, paw, and large intestine of non-castrated animals (P < 0.05). There was a negative linear association between level of food restriction and mass of blood, head, leather, paw, rumen, reticulum, abomasum, small intestine, large intestine; perirenal, omental, mesenteric and heart fat. The quantitative composition of carcass and non-carcass components of Santa Ines lambs is influenced by sex class and food restriction level.

Associations Between Food Restriction and Pressure-to-Eat Parenting Practices and Dietary Intake in Children: a Selective Review of the Recent Literature

The identification of modifiable determinants child dietary intake has become a public health priority. Food-related parenting practices, including pressure-to-eat and food restriction, have been identified as potentially significant determinants of dietary intake in children. This is a review of the literature to date that has explored the relationship between food restriction and pressure-to-eat and child dietary intake. In general, findings from laboratory-based studies and longitudinal studies suggest that children exposed to high levels of food restriction and pressure-to-eat are more likely to consume sugar-sweetened beverages, palatable snack foods, and calorie-dense food items than children exposed to lower levels. Results from the body of cross-sectional studies examining this relationship are decidedly less conclusive, yielding inconsistent and sometimes contradictory results. Overall, the concept of food-related parenting practices as a potentially modifiable factor with the potential to positively impact child dietary intake patterns continues to be worth pursuing through additional future research.

Do Parents Treat Siblings Similarly or Differently with Regard to Feeding Practices, Weight-Related Conversations, and Support for Physical Activity? An Exploratory Analysis.

It is unknown if parents with more than one adolescent child use similar or different parenting practices of relevance to weight-related health with different children. In particular, it is unclear whether parenting practices differ based on whether siblings are discordant on weight status (i.e., one is overweight/obese, one is nonoverweight/obese) or are different sexes. Data from two linked population-based studies, Eating and Activity in Teens (EAT) 2010 and Families and Eating and Activity in Teens (F-EAT), were used in this exploratory cross-sectional analysis. Participants included socioeconomically and racially/ethnically diverse parents (n = 57; 93% females) and adolescent siblings (n = 57 pairs; 60% girls; mean age = 14.5, range = 11-18). Students filled out surveys and had anthropometric measures taken in school. Parents filled out mailed surveys in their homes. Overall, results from this exploratory study showed limited evidence that parents use different parenting practices with adolescents of different weight status or sex. However, potentially important patterns emerged when exploring parenting practices and siblings' weight status. For example, within sibling dyads with discordant weight status, parents reported significantly more negative weight-related conversations with overweight/obese siblings compared to nonoverweight/obese siblings (p < 0.05). Although observed differences were not statistically significant, parents also reported higher levels of food restriction (p = 0.05) and encouragement to diet (p = 0.07) with overweight/obese siblings compared to nonoverweight/obese siblings. There were no significant differences in parenting practices by adolescent sex. Results generally suggest that parents use similar parenting practices with adolescent siblings. However, notable patterns emerged when examining parenting practices and siblings' weight status that may be important to explore in future research.

Parent/Adolescent Weight Status Concordance and Parent Feeding Practices.

Previous studies have examined the independent influence of mother's weight status or child's weight status on parents' use of specific feeding practices (ie, food restriction, pressure-to-eat). However, studies have not examined the mutual influence of parents' and adolescents' weight status on parents' feeding practices. This study examines the relationship between parent and adolescent weight status concordance and discordance and parent feeding practices. Data from 2 linked population-based studies, Eating and Activity in Teens (EAT) 2010 and Families and Eating and Activity in Teens (F-EAT), were used for cross-sectional analysis. Parents (n = 3252; 63% female; mean age 42.6 years) and adolescents (n = 2153; 54% female; mean age 14.4 years) were socioeconomically and racially/ethnically diverse. Anthropometric assessments and surveys were completed at school by adolescents, and surveys were completed at home by parents. Parents used the highest levels of pressure-to-eat feeding practices when parents and adolescents were both nonoverweight compared with all other combinations of concordant and discordant parent/adolescent weight status categories. Additionally, parents used the highest levels of food restriction when parents and adolescents were both overweight/obese compared with all other combinations of concordant and discordant parent/adolescent weight status categories. Sensitivity analyses with 2-parent households revealed similar patterns. Results suggest that parents use feeding practices in response to both their adolescents' and their own weight status. Results may inform health care providers and public health interventionists about which parent/adolescent dyads are at highest risk for experiencing food restriction or pressure-to-eat parent feeding practices in the home environment and whom to target in interventions.

Tissue vitamin concentrations are maintained constant by changing the urinary excretion rate of vitamins in rats' restricted food intake.

We previously reported that mild food restriction induces a reduction in tryptophan-nicotinamide conversion, which helps to explain why death secondary to pellagra is pandemic during the hungry season. In this study, we investigated the levels of B-group vitamins in the liver, kidney, blood, and urine in rats that underwent gradual restriction of food intake (80, 60, 40, and 20% restriction vs. ad libitum food intake). No significant differences in the B-group vitamin concentrations (mol/g tissue) in the liver and kidney were observed at any level of food restriction. However, the urine excretion rates exhibited some characteristic phenomena that differed by vitamin. These results show that the tissue concentrations of B-group vitamins were kept constant by changing the urinary elimination rates of vitamins under various levels of food restriction. Only vitamin B12 was the only (exception).