Over the past ten years, ultrasonic measuring instruments have become most widespread in industrial measurements of the flow and quantity of various energy resources. Such instruments differ in design, method of obtaining the output signal, number and topology of acoustic waves propagation and, accordingly, have different metrological performances. The accuracy of the measured signal formation is determined by the quality of the flow sensor. At the same time, the components of quality are metrological performances, manufacturability of the design, ease of setup, cost and others. The purpose of the work is to compare, analyze and evaluate the quality of flow measurements when using a single-channel ultrasonic sensor with a complex trajectory of the measuring beam and a multi-path (multichord) ultrasonic sensor. As a result of simulation modeling, distributions of flow velocities in longitudinal sections and cross sections were obtained, correction factors for the measured signal were determined, and pressure losses were calculated. A comparative analysis of the measurement quality of the investigated flow sensors made it possible to identify the advantages of using a single-path flow transducer with acoustic wave reflection. We are talking about the possibility of accurately outputting a useful signal, higher metrological sensitivity, higher measurement accuracy, as well as minimal impact on the measured medium due to the creation of smaller geometrically sized local hydrodynamic resistance along the length of the measuring path. The further research prospect is the study of ultrasonic flow measuring sensors with different topologies of acoustic channels when measuring and recording flow and quantity for different flow regimes of the measured medium.