Objective: Flood events, occurring as natural and unexpected phenomena, have become increasingly prevalent in recent decades. Assessing the probability of flood risk and creating flood zoning maps in vulnerable areas, particularly urban regions, are crucial for mitigating flood damages and managing such events. This research aims to determine the flood-prone zones along the Darakeh River, located in Tehran, the capital city of Iran, by integrating the hydraulic model HEC-RAS with Geographic Information System (GIS). Methods: After establishing the physiographic characteristics of the watershed, including area, perimeter, elevation, slope, and time of concentration, influential factors on flood occurrences such as permeability, hydrological soil groups, runoff potential, curve number, land use, and vegetation cover were identified. This information, along with other hydraulic data and flow specifications such as boundary conditions, roughness coefficients, and design discharge, was incorporated into the HEC-RAS model. The model was executed for different return periods of 2, 5, 10, 25, 50, and 100 years. Subsequently, the hydraulic model outputs were transferred to the GIS model to obtain the flood-prone zones along the Darakeh River for the aforementioned return periods. Results: As observed, in the middle section of the Khoshke Channel, which has a lower gradient, the floodplain exhibits a wider extent. Furthermore, along the course of the river and after passing through a stretch of the Khoshke Channel with a reduced gradient, the floodplain's area increases up to the location of the western flood channel. Conclusion: It is concluded that areas with lower river slopes exhibited larger flood-prone zones, highlighting the necessity of increased attention to prevent significant damages in urban areas during flood events.