To develop a screening and referral intervention for adolescents with unmet needs in an urban adolescent primary care clinic, by adapting “WE CARE,” a previously validated pediatric primary care social determinants of health (SDH) intervention. The pediatric WE CARE screener, which screens for six adverse SDH (food insecurity, housing instability, lack of heat, lack of high school degree, lack of quality childcare, and unemployment) was used as an initial guide in our adaptation process. Adolescent providers and clinic social workers reviewed it and assessed whether questions were representative of the psychosocial challenges faced by their patients. In these discussions, we identified the need to screen for after school activities and to broaden the education screen to also include the college level; conversely, we found a lack of need to screen for child care. In total, six adverse SDH (food insecurity, housing instability, lack of after school activities, lack of heat, lack of high school degree or college enrollment, and unemployment) were selected. Available community resources were also identified by a multidisciplinary care team; information sheets for adolescents with needs were accessible via the EMR. To vet the adapted screener, we interviewed adolescent patients over the course of three days in the adolescent clinic waiting room. The interviews assessed the face validity of the screener and adolescents reviewed the screener for understandability, ease to complete, feasibility, and acceptability. Participants’ suggestions were incorporated into the final version. The study screener readability was at the third-grade level using the Flesh-Kincaid grade level formula. Overall, it took participants <2 minutes to complete the screener. The screener was then piloted with adolescents. During the 3 day interview period (n=27), 33% of adolescents reported at least one of the needs included in the WE CARE screener; 30% of adolescents also reported having a friend with at least one of those needs. The most common self-reported unmet needs were with food (22%) and housing (22%), followed by after school activities (19%), utilities (19), employment (15%), and education (3%). 100% of adolescents reported that the screener was easy or very easy to fill out. 89% reported that they felt somewhat comfortable, comfortable, or very comfortable filling it out. Lastly, 93% of adolescents reported that the screener was somewhat useful, useful, or very useful. The adaptation of the pediatric WE CARE screener to address the needs of adolescents in an urban clinic was feasible and acceptable. The adolescent WE CARE intervention identified patients’ unmet needs and requests for help with SDH.