First Case Of Takotsubo Cardiomyopathy Research Articles

Takotsubo Syndrome Associated with COVID-19.

ObjectiveThe availability of public health information for optimised supportive care is critical during the COVID-19 pandemic. We describe the first case of COVID-19 complicated by Takotsubo cardiomyopathy.Materials and MethodsWe report the clinical, laboratory and radiological findings of a patient with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).ResultsThe nasopharyngeal swab was positive for SARS-CoV-2 and x-ray images demonstrated pathognomonic pneumonia. The patient developed tachycardia and the echocardiogram confirmed the diagnosis of Takotsubo cardiomyopathy.ConclusionsDoctors should be aware of the need to thoroughly study this new infection in order to understand its underlying mechanisms and related complications.LEARNING POINTSWe report the first case of Takotsubo cardiomyopathy associated with COVID-19.We discuss a rare presentation in the current pandemic.COVID-19 can be associated with cardiac complications, even after the onset of pneumonia, and so strict monitoring of these patients is essential.

‘Broken heart’ in acute-on-chronic liver failure

Takotsubo cardiomyopathy usually occurs as a result of catecholamine release causing myocardial ‘stunning’ during physical or emotional stress. Typically coronary angiogram shows normal or minor coronary artery disease and echocardiogram shows apical ballooning with basal wall hyperkinesia. The prognosis is excellent with good cardiac functional recovery within days to weeks. We report the first case of takotsubo cardiomyopathy in a patient with acute-on-chronic liver failure.

A Rare Double Trigger for Takotsubo Cardiomyopathy

A woman admitted to the hospital for a massive Pulmonary Embolism, developed, at stable emodinamic condition, a complex clinical scenario characterized by Crohn disease exacerbation, chest pain and worsening dyspnea. The electrocardiogram presented non-specific repolarization changes. Echocardiogram showed new Left Ventricle akinesis of the apex and medium-apical segments, hyperkinetic basal segment with reduced ejection fraction. Coronarography showed not significant coronary artery disease and typical left ventricle apical ballooning. Left ventricle dysfunction recovered spontaneously in few days. This is the first case of Takotsubo Cardiomyopathy in course of pulmonary embolism and Crohn disease exacerbation. Summary: Takotsubo Cardiomyopathy is a syndrome characterized by acute regional systolic dysfunction of the left ventricle, frequently related to psycho-physical acute stress and usually reversible, in the absence of significant coronary artery disease. No cases have been reported of Takotsubo Cardiomyopathy associated with pulmonary embolism in the context of Crohn disease reacutization.

Takotsubo Cardiomyopathy Associated with Peritonitis in Peritoneal Dialysis Patient

Takotsubo cardiomyopathy (TTC) is characterized by clinical and electrocardiographic features that mimic acute myocardial infarction, normal or mildly elevated cardiac enzymes, distinctive left ventricular wall motion abnormalities, and absence of significant obstructive coronary artery disease. Often there is a history of emotional stress and usually encountered in postmenopausal women. Excessive catecholamine stimulation plays an important role in the pathogenesis of TTC. Usually, this condition is reversible within several weeks to months. Only two cases of TTC were described in patients on hemodialysis. To our knowledge, we report the first case of TTC in peritoneal dialysis and the first case associated with peritonitis.

Takotsubo Cardiomiopathy after Acute Diarrhea

Takotsubo cardiomyopaty is a recently described syndrome characterized by transient left ventricular dysfunction, mimicking an acute coronary syndrome and usually precipitated by a physical or emotional stress. We report the first case of Takotsubo cardiomyopathy after acute diarrhea in a man. It may be argued that severe diarrhea in predisposed individuals may cause an acute stress resulting in increased sympathetic activity leading to this syndrome. Probably the relationship between the adrenergic system and the heart is more complex than general thought and the stimuli which favor an autonomic imbalance and precipitate the syndrome are very disparate in clinical practice.

Life-Threatening Complication During Percutaneous Ablation of Adrenal Gland Metastasis: Takotsubo Syndrome

A rare life-threatening complication during percutaneous cryoablation of an adrenal gland metastasis from a lung carcinoma is reported. The patient presented hypertensive crisis at the beginning of the thawing cycle, followed by electrocardiographic change which necessitated interruption of the procedure and his transfer to the intensive care unit with suspicion of heart infarct. There was a slight increase in cardiac enzyme levels, and ventricular angiography demonstrated transient hypokinesis-dyskinesis of the mid left ventricular segments without apical involvement, while the coronary arteries showed no significant stenosis on coronarography. These findings led to the diagnosis of Takotsubo cardiomyopathy left ventricular dysfunction syndrome. This is the first case of Takotsubo cardiomyopathy occurring as a complication during percutaneous ablation of an adrenal gland tumor.

Takotsubo cardiomyopathy in subarachnoid hemorrhage

The authors cannot conclude that they report the first case of Takotsubo cardiomyopathy associated with subarachnoid hemorrhage in a Caucasian patient.

Do statins delay the progression of aortic stenosis?

typical myocardial infarction and to allow for the arrival at the correct diagnosis of Takotsubo cardiomyopathy. On the other hand, emergency coronary angiography is more invasive for the patient undergoing emergency surgery. Especially in the patient who has a ruptured aortic aneurysm, oozing from the retroperitoneal small vessels injured by hematoma or surgical procedure is of concern because of the use of anticoagulants for catheterization. In our patient, despite a large blood transfusion including the platelet concentrates, platelet count on ICU admission was 6.0 3 10/mL. Therefore, we initially obtained transthoracic echocardiography by a cardiologist. According to the typical findings of Takotsubo cardiomyopathy revealed by echocardiography, normal creatine kinase MB fraction, and stable hemodynamic status, we selected careful observation. We routinely perform preoperative coronary angiography to assess the risk of perioperative myocardial infarction. Although preoperative intact coronary angiography is also meaningful to avoid needless or harmful coronary angiography in the perioperative period, as in the case with our patient, preoperative screening for heart disease is often limited to an electrocardiogram in emergency cases. However, in a certain situation, Takotsubo cardiomyopathy could be diagnosed by integration of clinical noninvasive modalities. We described the first case of Takotsubo cardiomyopathy after ruptured abdominal aortic aneurysm repair. We considered that diagnosis of this syndrome could be and should be made without invasive coronary angiography in certain situations to avoid further complications.

Intraoperative Left Ventricular Apical Ballooning: Transient Takotsubo Cardiomyopathy During Orthotopic Liver Transplantation

TRANSIENT LEFT VENTRICULAR (LV) apical ballooning, also referred to as “takotsubo syndrome,” is a stress-induced, reversible cardiomyopathy. The syndrome is characterized by transient LV apical and midsystolic dysfunction with basal hyperkinesis. The affected heart, when viewed by echocardiography or catheterization, mimics a shape described as a round-bottomed narrow-necked Japanese fishing pot used to trap octopus, which in Japanese is called “takotsubo.” 1 Bybee K.A. Kara T. Prasad A. et al. Systematic review: Transient left ventricular apical ballooning: A syndrome that mimics ST-segment elevation myocardial infarction. Ann Intern Med. 2004; 141: 858-865 Crossref PubMed Scopus (1218) Google Scholar The takotsubo syndrome was first described in the Japanese literature in 1990 and has since been characterized by transient LV apical ballooning in the absence of significant angiographic coronary artery stenosis and cardiomyopathy. 1 Bybee K.A. Kara T. Prasad A. et al. Systematic review: Transient left ventricular apical ballooning: A syndrome that mimics ST-segment elevation myocardial infarction. Ann Intern Med. 2004; 141: 858-865 Crossref PubMed Scopus (1218) Google Scholar , 2 Dote K. Sato H. Tateishi H. et al. Myocardial stunning due to simultaneous multivessel coronary spasms: A review of 5 cases. J Cardiol. 1991; 21: 203-214 PubMed Google Scholar In this article, the first case of takotsubo cardiomyopathy under general anesthesia in the United States is reported. 1 Bybee K.A. Kara T. Prasad A. et al. Systematic review: Transient left ventricular apical ballooning: A syndrome that mimics ST-segment elevation myocardial infarction. Ann Intern Med. 2004; 141: 858-865 Crossref PubMed Scopus (1218) Google Scholar , 3 Takigawa T. Tokioka H. Chikai T. et al. A case of undiagnosed “takotsubo” cardiomyopathy during anesthesia. Masui. 2003; 52: 1104-1106 PubMed Google Scholar , 4 Jabaudon M. Bonnin M. Bolandard F. et al. Takotsubo syndrome during induction of general anesthesia. Anaesthesia. 2007; 62: 519-523 Crossref PubMed Scopus (45) Google Scholar , 5 Ramakrishna G. Ravi B.S. Chandrasekaran K. Apical ballooning syndrome in a postoperative patient with normal microvascular perfusion by myocardial contrast echocardiography. Echocardiography. 2005; 22: 606-610 Crossref PubMed Scopus (25) Google Scholar , 6 Gavish D. Rozenman Y. Hafner R. et al. Takotsubo cardiomyopathy after general anesthesia for eye surgery. Anesthesiology. 2006; 105: 621-623 Crossref PubMed Scopus (40) Google Scholar This case report describes the intraoperative and postoperative events leading to the diagnosis of takotsubo cardiomyopathy. In addition, the diagnostic criteria and therapeutic modalities in the management of this acutely life-threatening cardiomyopathy are outlined. Takotsubo Cardiomyopathy in a Liver Transplant Recipient: A Diagnosis of Exclusion?Journal of Cardiothoracic and Vascular AnesthesiaVol. 23Issue 2PreviewTiwari and D'Attellis1 recently reported on transient takotsubo cardiomyopathy (TCM) during liver transplantation (LT). This was only the second case of this type of ventricular dysfunction ever reported in a LT recipient. The first such reported complication occurred several hours after LT.2 In 1 case, major complications triggered the event and in the other it developed spontaneously. In both cases, myocardial infarction was assumed; both patients underwent coronary arterial angiography, which excluded coronary artery disease as a cause in both cases. Full-Text PDF