Correlation Of Fine Needle Aspiration Cytology Research Articles

Correlation of FNAC with Histopathology in the Diagnosis of Differentiated Thyroid Carcinoma

Background: Fine-needle aspiration cytology (FNAC) is an important diagnostic tool for differentiating between neoplastic and non-neoplastic lesions of the thyroid. The current study was carried out to observe the comparison between preoperative fine needle aspiration cytology (FNAC) and postoperative Histopathology in the diagnosis of Differentiated Thyroid Carcinoma. Methods: This cross-sectional observational study was conducted in the department of Pathology, Rajshahi Medical College (RMC), Bangladesh from January 2019 to December 2020. Clinically suspected and diagnosed by FNAC, a total of forty patients of differentiated thyroid carcinoma attending outpatient and inpatient department of Otolaryngology, RMCH were enrolled in this study. Biopsy material was examined for histopathological diagnosis. Results: In this study, out of forty cases, 35 were papillary and 5 were follicular carcinoma. Mean age was 25.48+9.70 years and Male: Female was 1:6. Among 40 cases of FNAC findings, 33 cases (82.5%) were classic papillary carcinoma, 01(2.5%) case was follicular variant of papillary carcinoma, 5 cases were (12.5%) were follicular lesion and 01(2.5%) case was nodular goitre. Among 40 cases of histopathological findings, 32(80%) cases were classic papillary carcinoma, 03(7.5%) were follicular variant of papillary carcinoma and 5 cases were follicular carcinoma. In histopathological findings, none of them was nodular goitre. So, all FNAC findings were consistent with histopathological findings except nodular goitre which was diagnosed as classic papillary carcinoma in histopathology. Conclusion: FNAC is a safe and relatively accurate method for preoperative evaluation of thyroid malignancy before surgery. Therefore it is a reliable diagnostic test for evaluation of thyroid carcinoma. J Shaheed Suhrawardy Med Coll 2022; 14(1): 28-31

Ultrasonography and Fine Needle Aspiration Cytology Correlation of Thyroid Lesions

Ultrasonography and Fine Needle Aspiration Cytology Correlation of Thyroid Lesions

A Study of Correlation of Fine Needle Aspirationcytology and Histopathology in Diagnosis of Thyroidswelling

A Study of Correlation of Fine Needle Aspirationcytology and Histopathology in Diagnosis of Thyroidswelling

How accurate is fine-needle aspiration cytology (FNAC) for thyroid lesion: A correlation of FNAC with histopathology.

Indian population have large number of cases with deranged thyroid profile and swelling. Clinically apparent thyroid swelling in general population is 4% to 5%. Excising all the thyroid lesions is impracticable. Thus, final-needle aspiration cytology (FNAC) serves as the initial diagnostic test for the evaluation of thyroid swelling. The main purpose of FNAC is to differentiate the benign lesion from malignant ones, thereby reducing unnecessary surgeries. This study was conducted to establish a cytohistopathological correlation. FNAC of thyroid swellings was performed using 22G or 23G needle by aspiration or nonaspiration technique, preferable nonaspiration one. A proper correlation of the history, clinical presentation, thyroid profile, and cytopathology report was made, which helped us to make a proper diagnosis. All the cases that required surgery were planned for appropriate surgery and the resected specimen of thyroid was again sent to our department for histopathological examination. FNAC was performed on 39 patients (4 males and 35 females). The age group of patients were in the range of 11 to 60 years with a mean age of 38.60 years. Papillary thyroid carcinoma (PTC) and its variants were the most common in our study. Out of 39 surgeries performed, 19 (48.71%) specimens were found to be malignant. Among these 19 malignant cases, the highest number of malignancies were of PTC and its variants (14 cases). Statistical analysis showed sensitivity-90.91%, specificity-94.12%, positive predictive value-95.24%, negative predictive value-88.89%, and accuracy-92.31%. FNAC being cost-effective, patient-friendly, quick result along with high sensitivity, specificity, and accuracy makes it an initial diagnostic tool for preoperative evaluation of patients with thyroid swelling.

The Bethesda system for reporting thyroid fine needle aspirates: A study of 1763 patients; with histopathological correlations, in eastern India.

Fine-needle aspiration cytology (FNAC) is an important test for triaging patients with thyroid nodules. The 2007 National Cancer Institute Thyroid Fine-Needle Aspiration State-of-the-Science Conference helped instigate the recent publication of The Bethesda System for Reporting Thyroid Cytopathology (TBS). Terminology and therefore the probability of malignancy vary between pathologists and institutions. The purpose of this study was to evaluate a single institution's experience to determine if sub-classification (neoplasm versus lesion) aids in identifying patients at higher risk for malignancy. Also, an effort in regional and worldwide variation of significance of adoption of Bethesda classification has been evaluated. From 2018 to 2021, all patients with thyroid lesions' were evaluated for FNAC correlation with the surgical diagnosis. During this period, 1763 thyroid FNACs were reported. Histopathological examination (HPE) outcome data was available in 444 (25.2%) cases. The cytologic-histologic diagnostic discrepancy rate was 11.5%. The sensitivity and specificity of thyroid FNA for the diagnosis of malignancy were 71.4% and 49.5%, respectively. In our study, the maximum cases were benign (84.5%). The malignancy risk for the different categories in our study, as seen by follow-up HPE, has corroborated well with the Bethesda System. The current results indicated that FNAC provides an accurate diagnosis of thyroid malignancy. The classification is directly related to the risk of malignancy in each category and this helps in accurate clinical management of that category.

CORRELATION BETWEEN FINE NEEDLE ASPIRATION CYTOLOGY AND CORRESPONDING ULTRASOUND BIRADS SCORE IN MAMMARY MALIGNANCY

The aim of this study is to evaluate accuracy of ultrasound in diagnosing breast cancer and assessing correlation of radiological findings with findings of fine needle aspiration cytology (FNAC). Retrospective study was conducted at IbneSina Hospital& Multan Medical & Dental College Multan from July 2021 to December 2021. Study was conducted on 40 patients aged between 30 to 90 years having breast limps. Subjects underwent clinical and ultrasonic examination and BIRADS score was correlated with cytology data. Major ultrasonic finding was that irregular lesion was found in 21 (52.5%) subjects. In 10 (25%) patientsill defined lesion was found. FNAC revealed severe atypia in 7.5% and mammary carcinoma in 92.5% cases.BIRADS score V, IV and III were assigned to 75%, 20% and 5% cases respectively. Correlation of FNAC results with ultrasonic findings showed 90.6% accuracy of ultrasound in diagnosis of breast cancer. Ultrasonography provides accurate diagnosis of breast lesions and is recommended radiographic modality for assessing underlying cause of palpable breast mass.

Role of Ultrasound in the Diagnosis of Hepatocellular Carcinoma in Patients with Chronic Liver Disease

Background: Hepatocellular carcinoma (HCC) is a common cancer in humans. Its mortality ranks third among human malignancies. Cirrhosis of liver is a major contributor to hepatocellular carcinoma, about in 80% of the affected individuals. Fine needle aspiration cytology (FNAC) of the liver which is a minimal invasive procedure is essential to sort out primary and secondary neoplasm of the liver. Objective: The aim of this cross-sectional study was to determine the accuracy of ultrasound for diagnosis of HCC in comparison with FNAC findings. Materials and Methods: This study was done in the Radiology & Imaging Department in Enam Medical College & Hospital, Savar, Dhaka in collaboration with the Department of Pathology of the same institution for FNAC correlation during October 2017 to November 2019. A total number of 50 patients with CLD with known hepatic mass, referred to the department were included in the study. Ultrasound was done with TOSHIBA using low frequency curvilinear probe of 3.5 MHz. USGguided aspirations was performed using 18G needle under full aseptic measure. USG findings were validated by histopathology reports. Analysis was done by SPSS 19.0. Results: Mean age of the study population was 58.6 ± 10.9 years, of whom 37(74%) were male and 13 (26%) were female. Mean size of the hepatic lesions was 4.7 ± 1.08 cm. The lesions were characterized as iso-, hypo- and hyperechoic as compared with hepatic parenchyma. Doppler study shows both central and peripheral vascularity. Compared with FNAC findings, accuracy of USG findings was determined. Sensitivity of USG in detection of HCC was 97.7%, specificity was 66.7%, and positive prediction value 95.6% and negative prediction value 80%. Conclusion: Conventional USG can be used as a screening method in patients with CLD having hepatic masses. However, further workup is required for definite diagnosis. J Enam Med Col 2020; 10(3): 153-158

Efficacy of Ultrasound Intrinsic Compression Strain Elastography in Prediction of Malignancy in Thyroid Nodules with Fine Needle Aspiration Cytology Correlation

Background: Different diagnostic modalities are used to evaluate and diagnose efficiently thyroid nodules. These include Clinical Examinations, Thyroid Function Test (TFT), Scintiscan, Ultrasonography (USG), Fine Needle Aspiration Cytology (FNAC), and Histopathological examination. However, clinical assessment, TFT and USG have been poor parameters for assessing thyroid nodules. The objective is to this study was aimed to evaluate the efficacy of Ultrasound Elastography for the prediction of malignancy in thyroid nodule. Subjects and Methods:After obtaining written informed consent, demographic data such as age, sex and clinical features like, swelling, mode of onset, difficulty in swallowing, difficulty in breathing, hoarseness of voice obtained through an interview and recorded on predesigned and pretested proforma (Annexure II). Further these patients were subjected Grayscale Ultrasound, Ultrasound Elastography and FNAC. Results: Malignant lesions were noted in 19 patients on FNAC. Among them, 16 (84.21%) patients had malignant lesions while 3 (15.79%) patients had benign lesions based on combined USE and ECI criteria. This difference was statistically significant (p<0.001). The sensitivity of combined USE and ECI criteria in the diagnosis of malignant lesions was 84.21% with Specificity of 81.69%, PPV 55.17% and NPV 95.08%. Conclusion: Based on the findings of this study it may be concluded that, USE as determined by the Ragos criteria, TI RADS score are highly associated with malignant thyroid lesions and useful in differentiating the malignant thyroid lesions from benign ones.

Correlation of FNAC with Histopathology of breast lesions

Breast cancer is a commonest maliganancy of women globally. A papable breast lump is common diagnostic dilemma to surgeons. Fine needle aspiration cytology (FNAC) is simple rapid, accurate diagnostic tool for evaluating palpable breast lumps. Mammography is other screening modality for a breast lump which is routinely used method with simple, low cost with high accuracy.To differentiate and categories the breast lesions, and to study the correlation of FNAC with histopathology of palpable breast lumps.one and half year retrospective study carried out from January 2019 to June 2020 in the department of pathology, KBNIMS, Gulbarga. FNAC and Histopathology slides were retrieved and reviewed. All the slides were observed and findings recorded. Mammography findings were retrieved and recorded.The present study includes 125 cases out of which 101 cases (80.8%) were benign and 24 cases (19.2%) were malignant. Most common benign breast lesion was fibroadenoma (52.4%) and malignant lesion was infiltrating ductal carcinoma (75%). Frequencies of left breast lesions were high compare to right breast lesions. Out of 125 cases FNAC, 123 cases (98.4%) correlated with histopathology with sensitivity of 91.66%, specificity of 100%, positive predictive value (PPV) of 100%, negative predictive value (NPV) of 98% and accuracy of 98.4%.Out of 125 cases, mammography of 25 cases were retrieved with sensitivity of 87.5% and specificity of 94.11% with diagnostic accuracy of 92%.FNAC is a valuable diagnostic tool; provide rapid and reliable diagnosis in breast lesions.

Comparative study between fine needle aspiration cytology and histopathology in the diagnosis of breast lump

Aims and Objectives: 1.To compare the results of fine needle aspiration cytology (FNAC) and histopathological study of biopsy in detecting breast cancer in suspicious breast lumps in outpatient setting.; 2. To study the accuracy of FNAC in diagnosing various breast lumps.; 3. To know whether the cancer patients can be managed based on FNAC diagnosis alone without histological study. Methodology: It was a hospital based retrospective study carried out from the data retrieved from the Dept. of Pathology of Mysore Medical College, Mysore in a period from August 2016 – September 2016. Period of Study: 2 months, Sample Size: 50 patients. Results: In the present study, FNAC had sensitivity of 50%, specificity of 100%, positive predictive value of 100%, negative predictive value of 88.37%. In this case FNAC is highly specific with maximum positive predictive value. Conclusion: Benign neoplasms of the breast are more common than malignant one.The present study shows FNAC correlation with histopathology with high specificity and maximum positive predictive value. The sensitivity of FNAC is less compared to biopsy. However, FNAC can be used as an indicative diagnosis (one stop) for breast cancer examination in outpatient setting. Accuracy of FNAC enables to proceed with surgery or not. It bridges the gap between clinical evaluation and final surgical pathological diagnosis in majority of cases. It enables the clinician to obtain a diagnosis in high percentage of cases with minimal expenditure of time, amd money and often to avoid unnecessary surgery. Keywords: Fine needle aspiration cytology, Sensitivity, Specificity, Diagnostic accuracy.

A retrospective cytohistological correlation of fine-needle aspiration cytology with classification by the Milan System for Reporting Salivary Gland Cytopathology.

BackgroundBefore publication of the new classification system named the Milan System for Reporting Salivary Gland Cytopathology (MSRSGC) in 2018, there was no standard classification for salivary gland lesions obtained by fine-needle aspiration (FNA). We therefore aimed to evaluate the diagnostic utility of this system by retrospectively reviewing FNA samples using the MSRSGC and to determine their risk of developing into neoplasms and becoming malignant. MethodsRetrospective slide review and classification of salivary gland FNAs obtained over a 6-year period (2013–2018) at a single center were performed by two pathologists. The risks of neoplasm and malignancy for each category also were calculated. ResultsThis study surveyed 374 FNAs (371 patients) performed over a six-year period and selected 148 cases that included documented surgical follow-up (39.6%). Among the surgically treated cases, the distributions of FNA categories were as follows: non-diagnostic (ND; 16.9%), non-neoplastic (NN; 2.7%), atypia of undetermined significance (AUS; 3.4%), benign (BN; 54.7%), salivary gland neoplasm of uncertain malignant potential (SUMP; 10.1%), suspicious for malignancy (SM; 6.8%), and malignant (M; 5.4%). The risk of malignancy (ROM) was 24.0% for ND, 0% for NN, 40.0% for AUS, 2.5% for BN, 46.7% for SUMP, 100% for SM, and 87.5% for M. The overall diagnostic accuracy was 95.9% (142/148 cases). ConclusionsThe newly proposed MSRSGC appears to be a reliable system for classification of salivary gland lesions according to the associated ROM.

A Prospective Study of Ultrasonographic and FNAC Correlation of Thyroid Swellings with Histopathology.

The present study was undertaken to identify the complimentary role of high resolution ultrasonography and fine needle aspiration cytology (FNAC) in diagnosis of thyroid gland swelling pathology, also determine sensitivity, specificity and accuracy of both USG and FNAC and correlate it with histopathology report. Total 75 cases of thyroid swellings were evaluated in detail by taking history, doing clinical examination, USG, FNAC and histopathology. USG findings were correlated with the FNAC report. After thyroidectomy surgery, USG and FNAC results were followed up and correlated with histopathology report. Thyroid swellings were more common in the age group of 31-40years (34.66%) with female preponderance 70(93.33%). According to USG diagnosis, most common benign thyroid swelling was multinodular goitre (37.33). Amongst all the thyroid swellings, on FNAC, 17(18.67%) cases were diagnosed as a malignancy. 12(16%) cases were of follicular carcinoma which was the most common in this study. The sensitivity, specificity and diagnostic accuracy of USG was 86.66%, 91.66% and 90.66% respectively whereas sensitivity, specificity and diagnostic accuracy of FNAC was 93.3%, 95% and 94.66% respectively. USG and FNAC are simple methods of diagnosing thyroid gland swellings. The sensitivity, specificity and diagnostic accuracy of USG and FNAC for thyroid gland swellings was reasonably good. USG followed by FNAC increases the accuracy to diagnose various thyroid swellings so by which unnecessary thyroid gland surgery and hence complications can be avoided. However the most accurate and confirmatory diagnosis is given by histopathology.

The cyto-histopathological evaluation of breast lesions in a tertiary care hospital- A two years study

The cyto-histopathological evaluation of breast lesions in a tertiary care hospital- A two years study - ACHR- Print ISSN No: - 2581-5725 Online ISSN No:- 2456-9267 Article DOI No:- 10.18231/2456-9267.2019.0007, IP Archives of Cytology and Histopathology Research-IP Arch Cytol Histopathol Res

Ultrasonographic and fine needle aspiration cytology correlation of thyroid gland lesions: a study of 100 cases

<p class="abstract"><strong>Background:</strong> Thyroid gland is unique among endocrine organs as it is the largest endocrine gland in the body and the first to develop in the fetal life. There is approximately 4-5% incidence of clinically apparent thyroid lesions in general population. The goal of USG and FNAC diagnosis work up now is to select those patients for surgery who have a high likelihood of harboring malignancy in the nodule. Ultrasonography is the single most valuable imaging modality in the evaluation of the thyroid gland. Indications for thyroid USG include evaluation for palpable thyroid lesion or suspected thyroid enlargement and workup of thyroid lesions discovered incidentally.The present study is undertaken to evaluate the utility of FNAC in preoperative diagnosis of various thyroid lesions and to evaluate the efficacy of in USG and FNAC differentiating between benign and malignant lesions.</p><p class="abstract"><strong>Methods:</strong> A retrospective clinical study, 100patients, in the age group of equal to or above 18 years, with thyroid swellings, referred to the department of ENT, sent for USG and FNAC at radiology and pathology department during the period from July 2014 to July 2016. </p><p class="abstract"><strong>Results:</strong> Out of 100 cases, 6% were malignant, 94% were benign on grey scale ultrasound. Out of 6 malignant cases 2 cases were confirmed malignant by FNAC.</p><p class="abstract"><strong>Conclusions:</strong> High resolution grey scale ultrasound has emerged as initial imaging modality of choice for the evaluation of patients with thyroid enlargement. Ultrasound can detect solitary nodule, multiple nodules and diffuse thyroid enlargement. It can also differentiate solid and cystic lesions.</p>

Parotid Gland Tumours: Our Experience.

Salivary gland tumor comprises of approximately 3 to 10% of neoplasms of the head and neck region. Parotid gland is the most commonly involved salivary gland with an incidence of 62% followed by submandibular gland and other minor salivary gland tumors. However clinical course of benign and malignant tumors resemble each other in clinical findings, we require histopatholocal or cytological diagnosis for planning of management. To analyze parotid tumors retrospectively with following objectives. (1) Demographic distribution of parotid tumors. (2) To evaluate cytological and histopathological findings of parotid tumors. (3) Correlation of cytological and histopathological findings of parotid tumors. It was a retrospective observational study involving 31 patients who presented with parotid region swelling. Pre operative FNAC (fine needle aspiration cytology) and post operative histopathology were correlated. Surgical management depended on nature of disease. Correlation of FNAC and Histopathology: among 27 cases pre operative FNAC and post operative histopathology was same and in only 3 cases reports differed. One FNAC was inconclusive. In present study, Sensitivity of FNAC is 81.81%, Specificity is 94.73% and accuracy is 90%. FNAC is usually the first investigative modality, as it is a minimally invasive, cheap, OPD procedure that can differentiate benign from malignant tumors. Knowing preoperative pathological nature of disease can help in planning of surgical process.

Clinico-Radiological and Pathological Correlation of Breast Lesions in Patients Presenting to a Tertiary Hospital in Western Nepal

INTRODUCTION: Breast masses are frequently encountered problem, especially in females. Mammography and ultrasound are considered the standard imaging techniques for detection and evaluation of breast disease. The study was done to discuss the role of mammography and ultrasound in evaluation of breast mases with cytological correlation and to compare the sensitivity, specificity, positive predictive value and negative predictive value of ultrasonography6 with mammography in breast masses in different age groups and in patients with different breast density.MATERIALS AND METHODS: It was a non randomized prospective study carried out in Manipal teaching hospital Pokhara. The data for study was collected from patients with breast lump who attended the department of Radiology during the period from October 2013 to October 2014. Mammography and ultrasonography were performed on all cases presented with breast lump. A Fine needle aspiration cytology correlation was then performed with formed the basis for definitive judgement.RESULTS: The study analyzed 50 total numbers of patients presented to Radiology department who had breast lumps. Patients were aged between 20 and 75 years. Maximum numbe3r of patients were between 40 and 49 yrs constituting 40%. The mean age was 39.8 years ± 12.85 yrs. Ultrasound was significantly more sensitive than mammography in age less than 40 years. Mammogram had a significantly higher sensitivity than ultrasound in age group of more than 40 yrs. By using combined modalities (ultrasonography combined with mammogram), all benign cases were diagnosed correctly. For malignant breast masses, 10% were diagnosed as false negative but no cases were diagnosed false positive by combined modalities. Ultrasound was more sensitive than mammography in dense and heterogeneously dense breast whereas mammography was more sensitive than ultrasound in predominantly fatty breast.CONCLUSION: Combination of ultrasound and mammogram is more sensitive than other modality alone.Journal of Universal College of Medical Sciences, Vol. 5, No. 2, 2017, Page: 40-44

A study of correlation of fine-needle aspiration cytology with postoperative histopathological examination in patients with either solitary thyroid nodule or multiple nodules

Background Fine-needle aspiration cytology (FNAC) of the thyroid gland is now a well-established, first-line diagnostic test for the evaluation of thyroid nodules with the main purpose of confirming benign lesions and thereby, reducing unnecessary surgery. Different imaging techniques are now used for diagnosis of thyroid nodules like radionucleotide scanning and ultrasonography. However, FNAC is still regarded as the single most accurate and cost-effective procedure, particularly if ultrasound is used as a guide for better sample collection, especially for cystic lesions. Aim The aim of the work is to evaluate the correlation of preoperative FNAC with postoperative histopathological examination in patients with either solitary thyroid nodule and multiple nodules. Patients and methods This prospective study was done between April 2016 and November 2017 on 100 patients presented to the General Surgical Department with either solitary or multiple thyroid nodule. This was done to assess the correlation between preoperative FNAC and postoperative histopathological examination. Results Statistical analysis of our study showed sensitivity, specificity, accuracy, false-positive fraction, false-negative fraction, positive predictive value, and negative predictive value of FNAC to be 92, 81, 84, 36, 3.3, 63, and 96%, respectively. Conclusion The FNAC is a sensitive, specific, and accurate initial diagnostic test for the preoperative evaluation of patients with thyroid swellings in our setting as well. The correlation of cytological and histopathological diagnoses is an important quality assurance method, as it allows cytopathologists to calculate their false-positive and false-negative results.

Correlation of fine-needle aspiration cytology and surgical excision in the diagnosis of patients with cancer

Background: Cancer is a generic term for a large group of diseases that can affect any part of the body. Other terms used are malignant tumors and neoplasms. Fine-needle aspiration cytology (FNAC) has been extensively used for many years in the diagnosis of cancers, especially breast cancers, but its use has gradually been reduced in some hospitals because of its controversial inadequate rates and suboptimal accuracy in inexperienced hands and in some cases conflicting reports when compared with the excised biopsy of the same lesion. This is a prospective study to correlate the cytological findings in patients diagnosed with cancer with the histological diagnosis on excision. Materials and Methods: This was a prospective study of 30 patients that attended the Department of Pathology, Federal Medical Centre, Birnin Kebbi, from July 2016 to June 2017. All patients who were diagnosed after FNAC as having a malignant lesion were followed up for surgery for their excision biopsy. FNAC of the 30 patients was performed using 23-gauge needle under direct palpation (27 cases) by the pathologist and by ultrasonographic guidance (3 cases) before the surgical excision. Specimen after excision was fixed in 10% buffered formalin and stained with routine hematoxylin and eosin. Diagnosis on FNAC was subsequently compared with diagnosis after excision. Immunohistochemistry studies using limited antibody panels (CD5, CD10, CD20, CD30, and Bcl-2) were used on some surgical tissues (mostly lymphoid tissues) using Genemed biotechnology protocol to arrive at a definitive diagnosis. Results: A total of 30 patients had FNAC of various cancers during the study period, and all patients had excision biopsy subsequently. The age range was 5–65 years, with the most common sites of FNAC been the breast 17 (56.7%), abdomen 5 (16.5%), and cervical lymph nodes 4 (13.3%). There was 100% concordance between the diagnosis on FNAC and the excised tissues. Conclusion: FNAC correlates very well with histology of the excised tissues and remains a useful tool to guide the clinician for better management of patients.

Evaluation of breast lesions by digital mammography and ultrasound along with fine-needle aspiration cytology correlation.

Screening and diagnostic efforts for breast cancer are critical because the disease has a high rate of successful outcomes with early identification and treatment. The mammography (MG) and Ultrasonography/ ultrasound (USG) are individually effective diagnostic modalities for detection of breast pathologies. This cross-sectional, prospective, hospital-based study was carried out with an aim to evaluate breast lesions using digital MG and ultrasonography (USG) independently and in combination with fine-needle aspiration cytology (FNAC) correlation. The sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of MG in detecting carcinoma breast were 77.77%, 97.72%, 87.5%, and 95.55%, respectively. The sensitivity, specificity, PPV, and NPV of USG in detecting carcinoma breast were 55.55%, 97.72%, 83.33%, and 91.48%, respectively. In our study population, 83.01% of breast lesions were benign, and of them, 77.27% were diagnosed by MG alone and 72.72% were diagnosed by USG alone. When these modalities were combined, 97.72% of the lesions were diagnosed. The correlation coefficients of MG alone (0.792), USG alone (0.631), and MG and USG combination (0.884) with FNAC are all positive, and P values are significant of all the modalities. This study confirms that the MG and ultrasound (USG) when combined have significantly higher sensitivity and NPV than observed for a single modality in detecting the both benign and malignant lesions of the breast.

“Ultrasongraphic And Colour Doppler Evaluation of Cervical Lymphadenopathy with fine Needle Aspiration Cytology Correlation.”

“Ultrasongraphic And Colour Doppler Evaluation of Cervical Lymphadenopathy with fine Needle Aspiration Cytology Correlation.”