Technological advances of virtual environments offer training opportunities that can leverage solutions that extend from game-based systems to extended reality devices. However, careful consideration must be applied to advance the state of the possible and leverage innovation in other technical fields to increase the immersion and fidelity of virtual environments. This panel will provide perspectives on the current human factors limitations, challenges, and opportunities within domains seeking to leverage virtual environments for training. First, presenters will address the needs for front end analyses to underpin implementation decisions, as well as engineering a systems of systems learning environment through a human performance data strategy. Next, discussions will focus on complementary technologies such as artificial intelligence and machine learning that offer opportunities to advance the utility, fidelity, and effectiveness of virtual environments for training. Finally, panel members will discuss the need to evaluate resulting technologies to ensure successful adoption and implementation.