The purpose of this study was to evaluate the influence of cognitive restructuring strategies on intermittent explosive disorder among female inmates’ violence towards male partners in selected women prisons in Kenya. The study helped to evaluate the influence of reframing on intermittent explosive disorder. The study was anchored on Social cognitive theory by Albert Bandura and self-evaluation maintenance theory by Abraham Tesser. The study used an Ex Post Facto research design. The study was carried out at Langata and Thika Women Prisons. Quantitative data was obtained from the sampled inmates using questionnaires; while qualitative data was collected using interview guides from the prison key informants. The study incorporated 8 constables, 4 counsellors, 3 chaplains as key informants. Stratified and proportionate simple random sampling was used to select a sample size of 307 inmates. Quantitative data was analyzed using both descriptive and inferential tests. Hypotheses were tested at p=.05 using Pearson’s Product Moment Correlation Coefficient. Qualitative data was analyzed thematically according to the study objectives. The findings showed there was a statistically nonsignificant positive relationship between reframing and intermittent explosive disorder as, [r (257) = .051, p = .417]. Increase in intensity of frame shift, target thoughts and evidence of thoughts led to increased traits of intermittent explosive disorder. Based on these findings, the study recommends that prison management through the ministry of Interior and Coordination of National Government, enhance provision of counselling programmes mbased on cognitive restructuring techniques in the prisons. Reframing as a technique would provide solutions on the past painful memories of the inmates; optimistically avoid violence and keep away from crime