This paper aims to present a comprehensive investigation to obtain the structural calculations needed to design a rigid panel of aluminum alloy for the wing box beam of an ATR 72–500 aircraft. For this design process, several types of materials, including composites like CFRP, are considered so it is possible to compare the actual existing part made of aluminum to them, thus checking the advantages these new materials offer. The research presents an introduction to structural design and provides a study of the relevant literature. The aircraft's principal characteristics and performance abilities were collected so that structural loads can be computed. Research used several methods, a design using conventional methods, applying the theory of elasticity is performed using the Theory of Farrar, allowing us to obtain an analytical solution to the problem, followed by checking the obtained results using Ansys FEM software combined with the parts being designed with CATIA. Furthermore, this same panel is calculated using composite materials instead of conventional aluminum, allowing us to compare both solutions. This research shed light on the intricate process of aircraft structural design, materials selection, and calculation methodologies, highlighting the ongoing pursuit of new and advanced materials. This paper makes clear that using composite materials presents several advantages over traditional ones, allowing for lighter, safer, more fuel-efficient, and more sustainable aircraft. The use of composite materials in the construction of airplane structures is driven by many factors. The results show that the chosen composite materials reduce weight, are durable, have low maintenance requirements, reduce noise, enhance fuel economy, and are resistant to corrosion.