ABSTRACTThis paper investigates the function of the artificial pancreas, which is devised based on a dynamical backstepping approach. The Bergman's minimal model, used to describe the glucose‐insulin system, has been extended to encompass the dynamics of the insulin pump and external disturbances to closely simulate real‐world scenarios. Three techniques, namely feedback linearization, conventional backstepping, and super‐twisting sliding‐mode control, are evaluated in comparison to dynamical backstepping in the context of regulating blood glucose levels in individuals with type‐1 diabetes. In order to enhance the comparison of the controllers, we have taken into account the measurement noise and faults in the insulin pump as well. Additionally, Monte‐Carlo analysis is utilized as a practical tool to experimentally evaluate the robustness of the nonlinear controllers against measurement errors and variations in model parameters for different individuals, as would be encountered in a clinical trial. The extensive numerical simulations confirm that the dynamical backstepping method closely emulates the functionality of the natural pancreas and surpasses the super‐twisting sliding‐mode control method, the feedback linearization method, and the conventional backstepping method when faced with measurement noise, insulin pump faults, and parameter variations.
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