Febrile Convulsions In Children Research Articles

Modified Amber Particles as a Stabilizer to Construct Oil-in-Water Pickering Emulsions for Improved Thermal Stability of Acorus tatarinowii Essential Oil.

Lingzhu Pulvis is a classic formulation for treating febrile convulsions in children. However, Acorus tatarinowii essential oil (AT-EO) in this prescription is prone to volatilization and oxidation, compromising the efficacy and quality control of this formulation. Herein, based on the concept of "combination of medicine and adjuvant", Pickering emulsion technology was applied to enhance the stability of AT-EO using modified amber as a stabilizer. Amber was a resinous medicinal powder in Lingzhu Pulvis and was modified into a suitable stabilizer for Pickering emulsion through surface modification. A thermal stability study indicated that Pickering emulsion, stabilized by modified amber, exhibited a higher retention rate of AT-EO and lower levels of peroxide value and malondialdehyde content compared to those of the pure AT-EO group after heat treatment at 40 °C for 1, 3, and 8 h. Additionally, component analysis in content and composition revealed that the volatile components of AT-EO in the Pickering emulsion were more stable during the thermal treatment process. This study convincingly illustrates the potential of a Pickering emulsion stabilized with modified medicinal powders to improve the thermal stability of the essential oil.

Hubungan Tingkat Pengetahuan Orang Tua Tentang Kejang Demam Pada Anak Usia 1-5 Tahun Di UPTD Puskesmas Penerokan Kecamatan Bajubang

Febrile seizures are seizures that occur in children aged 6 months to 5 years who experience an increase in body temperature (temperature above 38° C). Batanghari Regency is the district with the highest cases of febrile seizures in children. The health center with the highest incidence of febrile convulsions in children is Penerokan Community Health Center. The aim of the research was to determine the relationship between the level of parental knowledge about febrile seizures and the incidence of febrile seizures in children aged 1-5 years at the UPTD Penerokan Community Health Center. This research is a quantitative study, cross sectional design. Data collection was carried out on 24 July 2023 – 30 July 2023 at the UPTD Penerokan Community Health Center. The sample consisted of 87 respondents. The sampling technique is accidental sampling. The analysis carried out was univariate and bivariate analysis. The statistical test used is the chi square test. The research results showed that more than half of the children experienced febrile convulsions (62.1%), most of the parents' knowledge was lacking (37.9%), there was a relationship between the level of parental knowledge about febrile convulsions and the incidence of febrile convulsions (p value = 0.000). . Nurses try to increase parents' understanding regarding the management of children who experience febrile convulsions by providing flip sheets or posters that parents can display at home, which can be easily read so that when a febrile convulsion occurs, parents are prepared to deal with the problem of febrile convulsions in children.

Parents' Knowledge, Attitude, and Practice Regarding Febrile Convulsion in Children in Riyadh, Saudi Arabia.

Background Fever is a common presentation in pediatric age groups and is the most common reason for healthcare visits. Parents' knowledge is essential for early presentation to healthcare facilities and to prevent possible complications. Studies suggest that febrile convulsions (FCs) often cause stress and anxiety for parents, who often assume it may cause brain damage, future epilepsy attacks, mental retardation, physical injury, and even death. This study aims to assess the knowledge, attitude, and practices of FCs among parents. Methodology This cross-sectional study was conducted among parents living in Riyadh, Saudi Arabia, with children younger than 14 years of age. A self-administered questionnaire was distributed among the selected population using an online survey. The questionnaire included socio-demographic data, family experiences of FC, practice toward a child with FC, and questions assessing knowledge, attitude, and concerns. Results Of the 415 recruited parents, 350 (84.3%) were mothers, and 56.4% were government employees. Regarding monthly income, 172 (41.4%) were earning more than 15,000 SAR per month. The prevalence of parents with having a child with FC was 33%. Overall, 369 (88.9%) had poor knowledge, 41 (9.9%) had moderate knowledge, and only five (1.2%) had good knowledge levels. Regarding attitude, more than one-third (200, 35.2%), had a negative attitude, 205 (49.4%) were neutral, and the rest had positive attitude levels (64, 15.4%). Increased knowledge and attitude toward FC were associated with having a child or siblings of a child with FC. Regarding the practice and the plan of action for future FC occurrence, the most common was to rush the child to a doctor (94, 68.6%), followed by lowering the child's body temperature (78, 56.9%), and placing the child on his/her side (54, 39.4%). Conclusions There was an optimistic attitude toward a child with FC but knowledge was deficient. However, parents who had a child or siblings experiencing FC were more knowledgeable, while parents with higher education and better income tended to exhibit better attitudes when managing a child with FC. Further investigations are needed to establish the level of understanding and perspectives of parents when managing a child with FC.

Formulation and Evaluation of Diazepam as a Rectal Preparation

Diazepam has become a commonly used drug for treatment of acute repetitive epileptic seizures and febrile convulsions in children. Considering the advantages of rectal administration of diazepam, the objective of this study was to formulate and evaluate rectal hydrogels containing diazepam as a drug substance in combination with suitable co - solvents and preservatives.Prepared HPMC (hydroxypropyl methylcellulose) hydrogels containing different concentrations of diazepam (2, 4 and 6 mg I ml) manifested good quality in respect to physicochemical parameters (pH value, drug content, ingredients content and viscosity), antimicrobial efficiency and microbiological quality. Under the proposed HPLC conditions, satisfactory separation of diazepam and the preservatives used was achieved. In vitro release studies have shown that the total amount ofdiazepam was released in a period of 3 hours. Prepared formulations were stable for four months at 26 C (ambient temperature characteristic of the second climate zone

Research progress of febrile convulsions in children

Research progress of febrile convulsions in children

Evaluation Nurses Practice about Care of Children with Febrile Convulsion

Abstract
 Objective(s): To evaluate the nurses` practices for children who diagnosed with febrile convulsion.
 Methodology: A quantitative research, descriptive correlational design was used in this study, the study conducted on nurses who work in Al-Diwaniya Pediatrics Teaching Hospital-Iraq for Maternal and Children period from 12th September 2021 to 10th October 2022. A non- probability (convenience) sample has been applied to obtain the study goals. The study sample was (21) nurses who participate in the study. The study tool is composed of two parts: The first part is concerned with collection of nurses socio-demographic data obtained from the nurses by a self-administered questionnaire, while the second part is constructed to assess nurse’s practices about children with febrile convulsion, it consists of (42) closed-ended question. The validity of the study instrument was determined through the (15) of experts in the specialty field.
 Results: Findings demonstrated assessment of the study sample responses at the nurse’s practices concerning management of children with febrile convulsion in terms of mean and standard deviation.
 Conclusion: Nurses' practice abut care of children with febrile convulsion was poor apply.
 Recommendations: Researcher recommendations periodic in-service training program and regular lectures should be provided to nursing staff in order updating their knowledge and practice about care of children with febrile convulsion.
 . Keywords: Assessment, Nurses Practices, Febrile Convulsion Children

Main Causes and Effective Nursing Method of Acute Febrile Convulsion in Children

Main Causes and Effective Nursing Method of Acute Febrile Convulsion in Children

Clinical Analysis of the Relationship between Convulsion and Blood Electrolyte in Children

Objective: Febrile convulsion in children is age-dependent and genetic predisposition. However, mild electrolyte disturbances are not uncommon in such children. This study was to investigate the effect of electrolyte disturbance on febrile convulsion and to screen for febrile convulsion-related genes. Methods: This retrospective cohort study included children who admitted to the Pediatric Emergency Department of Guangzhou Women and Children’s Medical Center due to fever and febrile convulsion between May to December 2020. Clinical manifestations and serum electrolyte levels were recorded and analyzed by binary logistic regression on risk factors of convulsion, and children with family histories were screened for febrile convulsion-related genes. Results: This study included 322 children with fever: 161 in the febrile convulsion group (FC Group) including 71 in the single convulsion group (SC Group) and 90 in the multiple convulsion group (MC Group), and the control group consisted of 161 children with fever without convulsion and nervous system disease. Serum sodium, potassium and calcium in FC Group were lower than those in the control group (p Conclusion: Hyponatremia may be a relative risk factor in febrile convulsion, and for children with a family history of febrile convulsion and serum sodium lower than 133 mmol/L, related gene analysis can be performed.

Association between iron-deficiency anemia and febrile convulsion in children

Association between iron-deficiency anemia and febrile convulsion in children

Study on the Effect and Incidence of Adverse Events of Pre-hospital Emergency Guidance in the Treatment of Febrile Convulsion in Children

Study on the Effect and Incidence of Adverse Events of Pre-hospital Emergency Guidance in the Treatment of Febrile Convulsion in Children

Relationship between serum iron level and febrile convulsion in children

The aim of the present study was to evaluate the relationship between febrile convulsion, serum iron levels and whole blood parameters. This cross-sectional case-control study included patients aged 6 months-6 years-old brought to the department of pediatrics of Kütahya ParkHayat Hospital with febrile convulsions between January 2015 and December 2019. The patients were divided into two groups as: febrile with convulsions (study group; n= 47) and febrile without convulsions (control group; n= 35). Both groups were age and sex-matched. Some blood parameters such as mean serum iron, ferritin, Hb and MCV levels were used to compare the groups. Mean serum iron levels of the study and control groups were 33.7 ± 2.1 μg/dL and 56.3 ± 7.4 μg/dL (p<0.05), and serum ferritin levels were 27.3 ± 6.2 ng/mL and 31.1 ± 2.1 ng/ mL (p>0.05), respectively. Mean hemoglobin levels of the study and control groups were 10.6 ± 1.7 g/dL and 11.1 ± 1.4 g/dL (p <0.05), and mean MCV levels were 71.1 ± 1.2 fL and 73.2 ± 1.1 fL (p>0.05), respectively. In the light of the findings of this study, the low serum iron and ferritin levels may be reinforcing factors for developing febrile convulsion. However, multicentre studies with more patients are needed to reach a precise conclusion.

The Relationship Between Mother's Knowledge and Handling of Fever Seizures in Children aged 1-5 years in Central Village, Pancur Batu District in 2020

Febrile convulsion often found in children 3-5 years old. This problem is a seizure that occurs when the body temperature rises and is caused by the extracranium process. This research was to decide the relationship between mother’s knowledge and management of febrile convulsion in children 1-5 years old in the Tengah village of Pancur Batu district 2020. This research is a cross-sectional study. We used to simple random sampling technique with 30 respondents. We used a questionnaire for the instrument. The final results showed that the majority of mother's knowledge regarding the management of febrile seizures was in the good category (86.7%) and the majority of febrile seizure management was in the category (90.0%). The results of chi-square statistical test show there is a relationship between knowledge of the mother with the handling of febrile seizures in children in the Tengah village of Pancur Batu District in 2020 (p value = 0,039). This study is expected to be an alternative for health workers to increase the promotion and prevention of problems related to the first treatment of febrile seizures. A person's knowledge is a factor that can influence a mother to take action, the better the mother's knowledge of diseases or health problems, the better the handling and vice versa, if the mother's knowledge is less, the handling of health problems will be better. Health education to the community will be a means to increase knowledge about handling health problems in the community.

Risk Factors of Recurrent Febrile Convulsions in Children in AL-batool Teaching Hospital

Background: Febrile seizures are the most common convulsive disorder in infants and children. Its occurbetween the age of 6 and 60 mo.There are two type of febrile convulsion simple and complex; A simplefebrile seizure is a primary generalized, usually tonic-clonic, attack associated with fever, lasting for amaximum of 15 min, and not recurrent within a 24-hour period. A complex febrile seizure is more prolonged(>15 min), focal, and/or recurs within 24 hr .Aim of the study: To identify the risk factors for recurrence of febrile convulsions in children.Materials and Methods: This was a case-controlled study done at Al Batool teaching hospital .Studyconducted over a period of five months , from August 2018 to December 2018 . All children with febrileseizure belonging to age group of 6 months to 6 years were included in the study.Results : Compared to children with first attack of febrile convulsion, children with recurrent seizures wereyounger at onset (12_24mo.) (26% vs. 54%), mainly male (72% vs. 62%) and had more often family history(second degree relative), low degree of temperature (78% vs. 36%),simple febrile convulsion (52% vs.68%),duration of fever less than12 hours (78% vs. 70%), and frequent febrile illnesses (74% vs. 20%). firstdegree family history of febrile convulsion and family history of epilepsy were not significant risk factors.Conclusions: The risk factors associated with increased incidence of recurrence FC are: male sex, agebetween12_24 months at the onset of the first FC, family history of FC in a second degree relative, durationof fever <12 hours ,simple type of convulsion &frequent attack of febrile illness(>4per year).

Correlation of serum magnesium levels in febrile convulsions in children: a cross sectional comparative study

Background: Febrile convulsions is one of the most common type of seizures seen in children. It has been suggested that low serum magnesium (Mg) has occasionally been associated with epilepsy. A positive correlation of the hypomagnesemia with the severity of epilepsy was also found. The present study aimed to estimate the levels of serum magnesium in children with febrile convulsions and to compare serum magnesium levels with normal children.Methods: Fifty patients who were eligible after screening for inclusion and exclusion criteria were included in the study group after a signed written informed consent and 50 controls were also taken. A detailed history, clinical examination and these investigations were done – complete blood count (CBC) (Hb, DC and ESR), serum calcium, serum magnesium, serum electrolytes, random blood sugar and cerebrospinal fluid (CSF) analysis.Results: The serum magnesium level was normal in 45 patients (90%) with febrile convulsions, low levels in 4 cases (8%) and high levels seen in 1 case (2%). Serum magnesium levels were normal in all 50 controls. In this study, the serum magnesium levels has got no correlation in patients with febrile convulsion. So, routine magnesium supplementation need not be prescribed in normal subjects to prevent febrile convulsions.Conclusions: Routine measurement of serum levels of Mg, glucose and calcium are warranted in subject with febrile convulsions. However, large prospective studies are further required in future to establish the correlation of serum Mg and febrile convulsions so that a standard guidelines can be set up which could be followed universally.

Clinical and Paraclinical Aspects of Febrile Convulsions in Children at the Ziguinchor Peace Hospital: Documentary Study

Introduction: Febrile seizures are seizures associated with fever in children. They represent a frequent reason for consultation in pediatric emergencies. Febrile convulsions are often qualified as benign pathologies but they are a source of concern, explaining the number of tolls imposed on these children. The aim of the study was to report the practice to a hospital in Senegal.
 Materials and Methods: This is a retrospective study of children's records, from January 1, 2015 to January 31, 2020. Were included, patients aged less than or equal to 5 years, hospitalized in the pediatric department of the Ziguinchor Peace Hospital, for a febrile convulsion. Newborns and children with psychomotor development abnormalities were excluded. We have studied the clinical and etiological data.
 Results: We collected 85 (51 boys, 34 girls) cases of febrile convulsions, ie a hospital frequency of 10,6%. The mean age of the patients was 23,6 months, peaking in infants 12 to 18 months. The mean temperature was 38,8° C and the seizure was tonic-clonic in 64,7%. We noted 57 cases of simple febrile convulsions (67,1%) and 28 cases of complicated febrile convulsions (32,9%). The etiology of fever was dominated by otorhinolaryngologic infections (42,4%); malaria (18,8%) and bronchopulmonary infections (08,2%). The average length of hospital stay was 02,8 days. We deplored two deaths (02,4%).
 Conclusion: Febrile convulsions are common in children under 5 years old. They are secondary to respiratory tract infections and malaria.

Can we predict occurrence of febrile convulsions in children with fever by increased neutrophil-to-lymphocyte ratio and C-reactive protein?

Background: Febrile seizure (FS) is the most common seizure disorder in children and is a major challenge in pediatric practice because of its high incidence in young children, a lack of predictive indications and their tendency to recur. Age at first seizure, male sex, and family history of FS, duration of fever, and height of temperature are the only significant risk factors presently known for predicting FSs. Objectives: The objectives of the study were to determine whether alterations in basic laboratory parameters such as neutrophil-to-lymphocyte ratio (NLR) and serum C-reactive protein (CRP) are associated with first episode of FS in children. Materials and Methods: This retrospective observational study was conducted in a level 2 pediatric hospital. A total of 196 children between the age of 6 months and 60 months who presented with first episode of febrile convulsions constituted the study group (FS cases). A total of 196 febrile children who presented only with fever within the same time period were selected as controls. NLR, CRP, and other basic laboratory parameters were compared between FS cases and controls. Results: NLR and CRP were both higher among FS than controls. Median of NLR in FS and controls was 1.55 and 0.67 (p<0.001). Median CRP in FS and controls was 10.85 and 4.85 mg/dl, respectively (p<0.001). Conclusions: High suspicion of FS may be warranted in febrile children with raised NLR and CRP, and hence, these parameters may be considered as predictors for developing first episode of seizures in febrile children.

The Effect of Educational Interventions on Knowledge, Attitude and Practices of Mothers Regarding Febrile Convulsions in Children

The Effect of Educational Interventions on Knowledge, Attitude and Practices of Mothers Regarding Febrile Convulsions in Children

Electrocardiography Parameters Changes in Epilepsy and Febrile Convulsion Children Compared with Controls

AbstractEpilepsy and febrile convulsion are the most common neurological diseases with significant effect on cardiac functions. This study aimed to evaluate electrocardiography parameters alterations in epilepsy and febrile convulsion children compared with controls. In this comparison study, 270 children analyzed who shared equally in epilepsy, febrile convulsion, and healthy that aged from 0.5 to 5 years. The participants were collected from Ali ibn Abi Talib Hospital of Zahedan, Iran. Epilepsy confirmed based on definition of having at least two unprovoked seizures in 24 hours. Febrile convulsion was confirmed based on its definition by the International League against Epilepsy. Healthy children selected from those referred to the hospital with fever and without any underline diseases. Electrocardiography was performed by a pediatric cardiologist. Data were analyzed using SPSS 19 with p &lt; 0.05 significant level. Heart rate was higher in epilepsy (129.64 ± 27.63) compared with control (108.78 ± 26.01) and febrile convulsion (125.79 ± 25.38; X 2 = 28.701, p &lt; 0.001). S wave in lead V1 was higher in controls (0.72 ± 0.36) compared with epilepsy (0.58 ± 0.45) and febrile convulsion (0.58 ± 0.36). QT dispersion and QTc dispersion levels were higher in epilepsy than febrile convulsion children that both were higher than controls. Concluded that R in aVL, LV mass (LVM), QT dispersion, and QTc dispersion were higher significantly in epilepsy compared with febrile convulsion children. To maintain a good strategic treatment in patients with epilepsy and febrile convulsion, there is a need to assess alternations in ECG parameters, especially QT interval changes that lead to better comprehensive autonomic changes.

Investigating the correlation between serum folic acid level and febrile seizures in children: A clinical study

Introduction: Febrile seizure (FS) is a highly frequent presenting complaint in children. It is defined as a seizure that occurs in children between 6 to 60 months related to a fever of 38°C or more without any other explanatory causes of seizure such as evidence of central nervous system (CNS) infection or a previous seizure without fever. The aim od study is to evaluate mean folic acid serum levels in febrile children with or without seizures.Methods: The mean folic acid serum levels and demographic data of 100 children aged 6 to 60 months, admitted to the Ghaem Hospital of Mashhad, Iran in 2018-2019, were collected, where the patients with febrile seizure were considered as the case group and the febrile ones without seizure as the control group. The inclusion criteria were children aged 6 to 60 months with febrile seizures who were admitted to the pediatric ward. The exclusion criteria were having a past medical history of seizure, meningitis, or encephalitis.Results: There were 49 febrile convulsive children (cases) and 51 febrile children without a seizure (controls). The mean serum folic acid level was 7.07 and 9.89 ng/ml for cases and controls respectively (P-value < 0.001).Conclusion: Children with febrile seizures had significantly lower serum folic acid levels than febrile children without a seizure.

The Association between Iron Deficiency Anemia and Febrile Convulsion in Children

The Association between Iron Deficiency Anemia and Febrile Convulsion in Children