Features Of Contact Dermatitis Research Articles

Study of Latex Glove Associated Dermatoses Among Nurses in a Tertiary Care Hospital.

Introduction:Natural rubber latex (NRL) is processed from Hevea brasiliensis trees. Allergic reactions to certain proteins in the latex manifest as immediate hypersensitivity reactions and allergic reactions to chemicals added to latex during processing manifest as allergic contact dermatitis. Healthcare workers (HCWs) are at increased risk of developing latex allergies. As little data is available from India, this study was directed toward identifying the prevalence of latex glove-related dermatoses among nurses and the factors leading to it.Methodology:This cross-sectional study was undertaken among nurses in a private tertiary care hospital.Results:A total of 700 nurses were included in the study. Symptoms of latex allergy were present in 74 (10.6%) of study subjects, out of which 69 (9.9%) had features of contact dermatitis. Patch test was done in 50 subjects and was positive in 12 (24%); among them, patch test antigens were positive in 9 (18%) and a positive result to glove piece was seen in 3 subjects.Conclusions:Latex allergy in India is a significant problem; though lesser compared to western countries, its prevalence necessitates the development of pre-employment protocols to avoid workplace morbidity.

Clinical‐epidemiological features of contact dermatitis in rural and urban communities in northern Ethiopia: correlation with environmental or occupational exposure

The widespread diffusion of low-quality products as well as the local cultural habits could be a relevant cause of allergic diseases in developing countries. In the present observational study, we explored the prevalence of allergic contact dermatitis in both rural and urban settings in northern Ethiopia, where skin diseases represent a frequent cause of morbidity. Clinical features and specific reactivities in association with environmental or occupational exposure were investigated. We patch tested 480 consecutive patients, visited at the Mekele IDC, exhibiting symptoms of contact dermatitis. A detailed medical history of each patient was collected. A positive patch-test response was observed in 50% of subjects; nickel was the most frequent sensitizer (26.2%), followed by p-tert-butylphenol formaldehyde resin (10%), fragrance mix (7.1%), potassium dichromate (5.4%), cobalt chloride (4.6%), disperse blue (2.3%), and p-phenylenediamine (1.7%). Gender-related differences were analyzed for single allergen. Eczema represented the most common manifestation, affecting the head and neck as primary skin areas. While reactivity to nickel interested almost all the occupational categories, sensitization to other allergens could be ascribed to working habits or environmental exposure. The results gathered from this study, the first one conducted within the Tigray region in Ethiopia, confirm the need to take appropriate measures to limit the nickel rate in metal objects and may be useful to design allergenic series suitable for patch testing in those geographical settings.

Allergy to 2 new corticoid molecules.

6 cases of hypersensitivity to Tixocortol pivalate and 3 to Amcinonide are reported. The 9 female patients all presented with features of contact dermatitis.

Clinical Features of Contact Dermatitis Due to Neomycin

In general, allergic cutaneous sensitivity reactions, after the topical application of neomycin, are considered to be rare. Baer and Ludwig 1 reported the first case of contact sensitivity to neomycin. Sulzberger and Baer 2 stated that they occasionally saw contact sensitivity to this antibiotic. Epstein 3,4 was the first to report a series of patients with neomycin sensitivity. However, his patients did not present the typical and easily recognizable picture of contact dermatitis. In the majority of cases which he reported, for the most part, the diagnosis depended upon a heightened index of suspicion, rather than on the easy recognition of the classical clinical features of an acute contact dermatitis. In this series, Epstein was of the opinion that he proved the etiological role of neomycin by the demonstration of positive intradermal tests to the antibiotic. Patch tests with neomycincontaining ointments and/or 10% solution of