Feasibility Of Rules Research Articles

Development and application of microscopy review criteria of urinalysis combination of dry chemistry and flow cytometry

Objective To establish the review criteria of urinalysis combination of AX-4280 urine dry chemeical analyzer and UF-1000i urine particle analyzer at our laboratory. Methods A total of 4 049 samples were collected randomly from Beijing Hospital of Ministry of Health from December 2010 to December 2011. After analysis on automated analysis line, each sample was examined by two experienced technicians with double-blind method. Their mean results were regarded as the microscopic examination results. The automatic detection and microscopy results of 4 049 samples were analyzed by the UriAccess 3.0 software. The results included BLD LEU and PRO of AX-4280, RBC WBC and CAST of UF-1000i and microscopic examination. The microscopy results were set as the gold standard. And the values of true positive rate, false positive rate, true negative rate, false negative rate and review rate of different combinations of rules were calculated. Then 189 urine samples were examined to validate the feasibility of rules by false negative rate and review rate. Results After analysis, 47 rules were selected for microscopic review. The true positive rate of this review criteria was 32.38% (1 311/4 049), false positive rate 22.33% (904/4 049), true negative rate 43.12% (1 746/4 049), false negative rate 2.17% (88/4 049) and review rate 27.76% (1 124/4 049). The false negative rate of this review criteria was 1.06% (2/189) and review rate 26.46% (50/189). Two cases of missed diagnosis specimens came from renal outpatient department of internal medicine and department of traditional Chinese medicine, the microscopic results of RBC and WBC were 4/HP and 7/HP respectively. So this criteria would not cause a missed diagnosis for patients with severe kidney disease. Conclusions This review criteria can effectively screen the urine samples to diagnose patients with severe kidney disease. So this review criteria is suitable for the screening of urinalysis results at our laboratory. Key words: Urinalysis; Chemistry, analytical; Microscopy; Autoanalysis

The feasibility of the empirical rule for the estimation of fission neutron spectrum averaged cross sections for the (n, p) and (n, α) reactions

Abstract We have proposed the empirical rule useful to estimate the fission averaged cross sections of the (n, p) and (n, α) reactions. The feasibility of this rule is further approved by the fact that the newly measured values of the (n, p) reaction cross sections on 43Ca, 96Mo, 132Ba and 140Ce, and of the (n, α) reaction cross sections on 45Sc, 50Ti and 45Fe coincide with values predicted by this rule. The hitherto known values of these cross sections were erroneous and then deviated from this rule.