Family Risk Of Dyslexia Research Articles

Reading and emotional-behavioural development in Finnish children: a longitudinal study of associations

AbstractPoor reading has been linked to negative outcomes on a wide range of emotional-behavioural dimensions in children. However, little is known about the time course of these associations. In this study we analyse data from a sample of Finnish children (N = 199; 106 boys) which included measures of reading fluency in grade 1 (age 7 or 8), and emotional (anxiety, depression, and somatization) and behavioural (adaptability, aggression, attention, atypicality, hyperactivity, social skills, and withdrawal) development at ages 4, 5, 6 (pre-school) and 9 (school-aged). In a series of stepwise regression models that controlled for non-verbal IQ and family risk for dyslexia, we tested if pre-school emotional-behavioural measures were associated with school-aged reading fluency, and whether school-aged reading fluency was associated with later emotional-behavioural development. We also tested if these associations were moderated by reported gender. Consistent with previous longitudinal studies, we found that poorer attention before school was associated with poorer reading in the early school years which in turn was associated with higher levels of anxiety and inattention in children in middle school. None of these associations were moderated by gender.

Developing and validating an abbreviated adult reading history questionnaire in the Finnish and Dutch contexts

BackgroundThe adult reading history questionnaire (ARHQ) is frequently used in research on adult dyslexia and family risk for dyslexia. However, this measure is lengthy (23 items), reducing its applicability in studies with extensive assessment batteries.MethodsWe identified the best‐performing ARHQ items in a sample of 396 Finnish adults using exploratory factor analysis and item response theory. Consequently, we validated the brief questionnaire in independent Finnish and Dutch samples by comparing its performance with that of the complete questionnaire. We also evaluated how the scores on the questionnaires related to the scores on direct adult reading assessments in the Finnish samples. Finally, we tested how predictive parental questionnaires were of children's skills in the Dutch and one of the Finnish samples.ResultsFive items were selected to construct the short version of ARHQ. All of them relate to childhood/adolescent reading difficulties rather than current adult skills. The scores of the complete ARHQ significantly correlated with those of the abbreviated version in all samples. Moreover, in one of the samples, direct reading assessment scores had a stronger correlation with the short ARHQ than with the full version. Additionally, across all three samples parental scores on the short ARHQ were at least as predictive of children's reading skills as the complete ARHQ.ConclusionsThe short ARHQ proved to be on a par with the complete version in its usefulness for identifying adults with dyslexia. Future research should investigate whether the five selected items can effectively serve as a brief screening measure for adults with dyslexia in languages other than Finnish and Dutch.

A Bayesian Probabilistic Framework for Identification of Individuals with Dyslexia

ABSTRACT Purpose Bayesian-based models for diagnosis are common in medicine but have not been incorporated into identification models for dyslexia. The purpose of the present study was to evaluate Bayesian identification models that included a broader set of predictors and that capitalized on recent developments in modeling the prevalence of dyslexia. Method Model-based meta-analysis was used to create a composite correlation matrix that included common predictors of dyslexia such as decoding, phonological awareness, oral language, but also included response to intervention (RTI) and family risk for dyslexia. Bayesian logistic regression models were used to predict poor reading comprehension, unexpectedly poor reading comprehension, poor decoding, and unexpectedly poor decoding, all at two levels of severity. Results Most predictors made independent and substantial contributions to prediction, supporting models of dyslexia that rely on multiple rather than single indicators. RTI was the strongest predictor of poor reading comprehension and unexpectedly poor reading comprehension. Phonological awareness was the strongest predictor of poor decoding and unexpectedly poor decoding, followed closely by family risk. Conclusion Bayesian-based models are a promising tool for implementing multiple-indicator models of identification. Ideas for improving prediction and implications for theory and practice are discussed.

Statistical learning in children with a family risk of dyslexia.

The assumption that statistical learning is affected in dyslexia has generally been evaluated in children and adults with diagnosed dyslexia, not in pre‐literate children with a family risk (FR) of dyslexia. In this study, four‐to‐five‐year‐old FR children (n = 25) and No‐FR children (n = 33) completed tasks of emerging literacy (phoneme awareness and RAN). They also performed an online non‐adjacent dependency learning (NADL) task, based on the Serial Reaction Time (SRT) task paradigm. Children's accuracy (hits), signal sensitivity (d′) and reaction times were measured. The FR group performed marginally more poorly on phoneme awareness and significantly more poorly on RAN than the No‐FR group. Regarding NADL outcomes, the results were less straightforward: the data suggested successful statistical learning for both groups, as indicated by the hit and reaction time curves found. However, the FR group was less accurate and slower on the task than the No‐FR group. Furthermore, unlike the No‐FR group, performance in the FR group varied as a function of the specific stimulus presented. Taken together, these findings fail to show a robust difference in statistical learning between children with and without an FR of dyslexia at preschool age, in line with earlier work on older children and adults with dyslexia.

Rhythm discrimination and metronome tapping in 4-year-old children at risk for developmental dyslexia

Temporally accurate perception and production of rhythmic patterns are key factors related to language development and reading acquisition. Here we investigate rhythm discrimination and rhythm production in children who are at family risk or not at family risk for dyslexia, to compare group performance in these tasks prior to the start of reading instruction and to investigate the relation between individual children’s rhythmic abilities and pre-reading skills. Four-year-old children completed a rhythm discrimination task and a rhythm production task, both utilizing a temporal rate of 2 Hz, and also received pre-reading measures of non-word repetition, vocabulary, and letter knowledge. Controls outperformed at-risk children in the rhythm discrimination task and in the pre-reading measures. No group differences were observed in the rhythm production task, but individual differences in this task were related to scores of non-word repetition, vocabulary size, and letter knowledge. The data are discussed in terms of Temporal Sampling theory (Goswami, 2011).

Shared storybook reading with children at family risk of dyslexia.

BackgroundShared storybook reading is an important context for language learning and often constitutes young children's first encounter with the printed word. The quality of early shared reading interactions is a known predictor of language and reading development, but few studies have examined these interactions in children at family risk of dyslexia.MethodsThis exploratory study describes the quality of shared storybook reading between mothers and their 3‐ to 4‐year‐old children at family risk of dyslexia (FR; n = 18) in comparison with dyads with no known risk (no‐FR; n = 13). Mother–child interactions while sharing a familiar and an unfamiliar storybook were coded for type of extra‐textual talk (meaning‐related talk at the concrete and abstract levels; print‐related talk) and affective quality. Maternal and child language and literacy skills were considered as potential correlates of shared reading quality.ResultsThe linguistic and affective quality of shared reading was broadly comparable across FR and no‐FR dyads, particularly when sharing a book they knew well, with large within‐group variation. Mothers contributed more concrete meaning‐related talk when introducing an unfamiliar book to their children; children contributed more extra‐textual talk overall when sharing a familiar book. Maternal language, but not reading, skills were related to the linguistic quality of shared reading. The affective quality of reading interactions was rated more highly in dyads where mothers and children had stronger language skills.ConclusionsThese results suggest that the quality of shared reading does not vary systematically as a function of children's risk of dyslexia but is related to maternal language skills. This finding needs to be replicated in a larger sample in order to better understand the risk and protective factors associated with dyslexia.Highlights What is already known about this topic The quality of extra‐textual talk during shared reading between parents and preschoolers predicts later language and literacy outcomes in typically developing children.The affective quality of early shared reading predicts children's motivation to read independently in later childhood.Children at family risk of dyslexia are more likely than their peers with no family risk to have difficulty learning to read and may show weaknesses in oral language skills. What this paper adds The linguistic and affective quality of shared reading between mothers and preschool children is broadly similar when children are at family risk of dyslexia compared with no family risk.The type and quantity of extra‐textual talk contributed by mothers and children appears to differ according to the familiarity of the storybook, but replication of the findings in a larger sample is required.The linguistic and affective quality of shared reading is related to maternal language skills. Implications for theory, policy or practice Shared storybook reading offers rich language learning opportunities for children at family risk of dyslexia.Maternal language skills may be an important determinant of the interactional quality of shared reading.The linguistic and affective quality of shared reading is not clearly associated with maternal reading difficulties.

Speech discrimination in infants at family risk of dyslexia: Group and individual-based analyses

Deficiencies in discriminating and identifying speech sounds have been widely attested in individuals with dyslexia as well as in young children at family risk (FR) of dyslexia. A speech perception deficit has been hypothesized to be causally related to reading and spelling difficulties. So far, however, early speech perception of FR infants has not been assessed at different ages within a single experimental design. Furthermore, a combination of group- and individual-based analyses has not been made. In this cross-sectional study, vowel discrimination of 6-, 8-, and 10-month-old Dutch FR infants and their nonrisk (no-FR) peers was assessed. Infants (N = 196) were tested on a native English /aː/–/eː/ and non-native English /ɛ/–/æ/ contrast using a hybrid visual habituation paradigm. Frequentist analyses were used to interpret group differences. Bayesian hierarchical modeling was used to classify individuals as speech sound discriminators. FR and no-FR infants discriminated the native contrast at all ages. However, individual classification of the no-FR infants suggests improved discrimination with age, but not for the FR infants. No-FR infants discriminated the non-native contrast at 6 and 10 months, but not at 8 months. FR infants did not show evidence of discriminating the contrast at any of the ages, with 0% being classified as discriminators. The group- and individual-based data are complementary and together point toward speech perception differences between the groups. The findings also indicate that conducting individual analyses on hybrid visual habituation outcomes is possible. These outcomes form a fruitful avenue for gaining more understanding of development, group differences, and prospective relationships.

The Role of Paired Associate Learning in Acquiring Letter-Sound Correspondences: A Longitudinal Study of Children at Family Risk for Dyslexia

ABSTRACT Visual-verbal-paired associate learning (PAL) is strongly related to reading acquisition, possibly indexing a distinct cross-modal mechanism for learning letter-sound associations. We measured linguistic abilities (nonword repetition, vocabulary size) longitudinally at 3.5 and 4.0 years, and visual-verbal PAL and letter knowledge at 4.0 and 4.5 years, in pre-reading children either at family risk for dyslexia (N = 27) or not (N = 25). Only nonword repetition predicted individual differences in later letter-sound knowledge, and PAL did not make a cross-sectional nor a longitudinal contribution. The data show a continuous relationship between linguistic processing abilities and letter-sound learning, with no independent role for PAL.

Language difficulties are a shared risk factor for both reading disorder and mathematics disorder

Disorders of reading and mathematics co-occur at greater than chance rates, but they are often studied separately. This article reports the reading and arithmetic outcomes at 9 years of age from a longitudinal study of 224 children at high risk for dyslexia. Using a cutoff at the 10th centile, groups of children with reading disorder (RD), mathematics disorder (MD), and comorbid reading disorder and math disorder (RD&MD) were identified. The risk of these disorders was elevated in children selected in preschool with language difficulties or at family risk for dyslexia. There was a high degree of comorbidity between RD and MD, and many cases—particularly in the comorbid group—also reached the diagnostic threshold for developmental language disorder (DLD). On measures of language, phoneme awareness, rapid automatized naming (RAN) digits, and rated inattention, there was a stepwise pattern: RD > MD > RD&MD. Poor language was associated with each disorder and appears to be a cognitive risk factor for RD, MD, and RD&MD. These findings suggest that there are shared genetic risk factors operating for both RD and MD.

An Evaluation of the Efficacy of GraphoGame Rime for Promoting English Phonics Knowledge in Poor Readers

Here we report further analysis of data drawn from a Randomized Controlled Trial (RCT) run in the United Kingdom designed to evaluate the efficacy of an adaptive software game to aid the learning of English phonics, GraphoGame Rime. We evaluate the efficacy of GraphoGame Rime for the “top half” of players in the RCT, children aged 6 to 7 years who played above the group mean play progress point (95 children). We also analyse 3 sub-groupings of this cohort. The GraphoGame family of games in different languages was originally designed to support children at family risk of dyslexia, hence we analysed data for the subgroup of the GraphoGame Rime children who were struggling in school and had Individual Education Plans (IEPs). Secondly, we analysed data from the younger children in the RCT, born in the Spring and Summer months, as international studies of GraphoGame have found the strongest effects during the first year of reading tuitionand our participants were in their second year of reading tuition. Finally, we analysed GraphoGame Rime data from players in schools rated as “requiring improvement”. Schools that are found to be “requiring improvement” in the United Kingdom are encouraged to use additional teaching strategies to achieve better outcomes. GraphoGame Rime is relatively cheap to acquire and easy to implement, hence if it offers significant gains over “business-as-usual” this would be a valulable additional strategy for such schools. We find that GraphoGame Rime is more effective than “business-as-usual” in developing knowledge of English phonics for all of the groupings analysed. We conclude that the supplementary use of GraphoGame Rime in addition to ongoing classroom literacy instruction can benefit children in learning phonic decoding and spelling skills.

Subcortical auditory neural synchronization is deficient in pre-reading children who develop dyslexia.

Auditory processing of temporal information in speech is sustained by synchronized firing of neurons along the entire auditory pathway. In school-aged children and adults with dyslexia, neural synchronization deficits have been found at cortical levels of the auditory system, however, these deficits do not appear to be present in pre-reading children. An alternative role for subcortical synchronization in reading development and dyslexia has been suggested, but remains debated. By means of a longitudinal study, we assessed cognitive reading-related skills and subcortical auditory steady-state responses (80Hz ASSRs) in a group of children before formal reading instruction (pre-reading), after 1year of formal reading instruction (beginning reading), and after 3years of formal reading instruction (more advanced reading). Children were retrospectively classified into three groups based on family risk and literacy achievement: typically developing children without a family risk for dyslexia, typically developing children with a family risk for dyslexia, and children who developed dyslexia. Our results reveal that children who developed dyslexia demonstrate decreased 80Hz ASSRs at the pre-reading stage. This effect is no longer present after the onset of reading instruction, due to an atypical developmental increase in 80Hz ASSRs between the pre-reading and the beginning reading stage. A forward stepwise logistic regression analysis showed that literacy achievement was predictable with an accuracy of 90.4% based on a model including three significant predictors, that is, family risk for dyslexia (R=.31), phonological awareness (R=.23), and 80Hz ASSRs (R=.26). Given that (1) abnormalities in subcortical ASSRs preceded reading acquisition in children who developed dyslexia and (2) subcortical ASSRs contributed to the prediction of literacy achievement, subcortical auditory synchronization deficits may constitute a pre-reading risk factor in the emergence of dyslexia.

School-entry language outcomes in late talkers with and without a family risk of dyslexia.

Children with familial risk (FR) of dyslexia and children with early language delay are known to be at risk for later language and literacy difficulties. However, research addressing long-term outcomes in children with both risk factors is scarce. This study tracked FR and No-FR children identified as late talkers at 2 years of age and reports development from 4;6 through 6 years. We examined the possible effects of FR-status and late talking (LT) status, respectively, on language skills at school entry, and whether FR-status moderated the associations between 4;6-year and 6-year language scores. Results indicated an effect of LT status on language at both ages, while FR status affected language skills at 6 years only. The interaction between LT and FR statuses was not significant, implying that LT status affected language skills independently of the child's FR status. A proportion of late talkers developed typical language at 6 years of age, while some FR children with typical vocabulary skills in toddlerhood had emerging developmental language disorder by school entry. FR status had a moderating effect on the association between expressive grammar at ages 4;6 and 6 years. Possible explanations for the effect of FR status on language skills are discussed. We highlight limitations in the study size and suggest how these preliminary findings can inform future research.

Novel word learning deficits in infants at family risk for dyslexia.

Children of reading age diagnosed with dyslexia show deficits in reading and spelling skills, but early markers of later dyslexia are already present in infancy in auditory processing and phonological domains. Deficits in lexical development are not typically associated with dyslexia. Nevertheless, it is possible that early auditory/phonological deficits would have detrimental effects on the encoding and storage of novel lexical items. Word-learning difficulties have been demonstrated in school-aged dyslexic children using paired associate learning tasks, but earlier manifestations in infants who are at family risk for dyslexia have not been investigated. This study assessed novel word learning in 19-month-old infants at risk for dyslexia (by virtue of having one dyslexic parent) and infants not at risk for any developmental disorder. Infants completed a word-learning task that required them to map two novel words to their corresponding novel referents. Not at-risk infants showed increased looking time to the novel referents at test compared with at-risk infants. These findings demonstrate, for the first time, that at-risk infants show differences in novel word-learning (fast-mapping) tasks compared with not at-risk infants. Our findings have implications for the development and consolidation of early lexical and phonological skills in infants at family risk of later dyslexia.

Atypical gray matter in children with dyslexia before the onset of reading instruction

Many studies have focused on neuroanatomical anomalies in dyslexia, yet primarily in school-aged children and adults. In the present study, we investigated gray matter surface area and cortical thickness at the pre-reading stage in a cohort of 54 children, 31 with a family risk for dyslexia and 23 without a family risk for dyslexia, of whom 16 children developed dyslexia. Surface-based analyses in the core regions of the reading network in the left hemisphere and in the corresponding right hemispheric regions were performed in FreeSurfer. Results revealed that pre-readers who develop dyslexia show reduced surface area in bilateral fusiform gyri. In addition, anomalies related to a family risk for dyslexia, irrespectively of later reading ability, were observed in the area of the bilateral inferior and middle temporal gyri. Differences were apparent in surface area, as opposed to cortical thickness. Results indicate that the neuroanatomical anomalies, since they are observed in the pre-reading phase, are not the consequence of impoverished reading experience.

Lexical and grammatical development in children at family risk of dyslexia from early childhood to school entry: a cross-lagged analysis.

The aim of this study was to examine (a) the development of vocabulary and grammar in children with family-risk (FR) of dyslexia and their peers with no such risk (NoFR) between ages 1;6 and 6;0, and (b) whether FR-status exerted an effect on the direction of temporal relationships between these two constructs. Groups were assessed at seven time-points using standardised tests and parental reports. Results indicated that although FR and NoFR children had a similar development in the earlier years, the FR group appeared to perform significantly more poorly on vocabulary at the end of the preschool period. Results showed no significant effect of FR status on the cross-lagged relations between lexical and grammatical skills, suggesting a similar developmental pattern of cross-domain relations in both groups. However, FR status seemed to have a significantly negative association with vocabulary and grammar scores at age 6;0, resulting in language outcomes in favour of NoFR children.

Brain activity patterns of phonemic representations are atypical in beginning readers with family risk for dyslexia.

There is an ongoing debate whether phonological deficits in dyslexics should be attributed to (a) less specified representations of speech sounds, like suggested by studies in young children with a familial risk for dyslexia, or (b) to an impaired access to these phonemic representations, as suggested by studies in adults with dyslexia. These conflicting findings are rooted in between study differences in sample characteristics and/or testing techniques. The current study uses the same multivariate functional MRI (fMRI) approach as previously used in adults with dyslexia to investigate phonemic representations in 30 beginning readers with a familial risk and 24 beginning readers without a familial risk of dyslexia, of whom 20 were later retrospectively classified as dyslexic. Based on fMRI response patterns evoked by listening to different utterances of /bA/ and /dA/ sounds, multivoxel analyses indicate that the underlying activation patterns of the two phonemes were distinct in children with a low family risk but not in children with high family risk. However, no group differences were observed between children that were later classified as typical versus dyslexic readers, regardless of their family risk status, indicating that poor phonemic representations constitute a risk for dyslexia but are not sufficient to result in reading problems. We hypothesize that poor phonemic representations are trait (family risk) and not state (dyslexia) dependent, and that representational deficits only lead to reading difficulties when they are present in conjunction with other neuroanatomical or-functional deficits.

Developmental Outcomes for Children at High Risk of Dyslexia and Children With Developmental Language Disorder.

We followed children at family risk of dyslexia and children with preschool language difficulties from age 3½, comparing them with controls (N = 234). At age 8, children were classified as having dyslexia or Developmental Language Disorder (DLD) and compared at earlier time points with controls. Children with dyslexia have specific difficulties with phonology and emergent reading skills in the preschool period, whereas children with DLD, with or without dyslexia, show a wider range of impairments including significant problems with executive and motor tasks. For children with both dyslexia and DLD, difficulties with phonology are generally more severe than those observed in children with dyslexia or DLD alone. Findings confirm that poor phonology is the major cognitive risk factor for dyslexia.

Language Skills, but Not Frequency Discrimination, Predict Reading Skills in Children at Risk of Dyslexia

This study evaluated the claim that auditory processing deficits are a cause of reading and language difficulties. We report a longitudinal study of 245 children at family risk of dyslexia, children with preschool language impairments, and control children. Children with language impairments had poorer frequency-discrimination thresholds than controls at 5.5 years, but children at family risk of dyslexia did not. A model assessing longitudinal relationships among frequency discrimination, reading, language, and executive function skills showed that frequency discrimination was predicted by executive skills but was not a longitudinal predictor of reading or language skills. Our findings contradict the hypothesis that frequency discrimination is causally related to dyslexia or language impairment and suggest that individuals at risk for dyslexia or who have language impairments may perform poorly on auditory processing tasks because of comorbid attentional difficulties.

Early cognitive predictors of PISA reading in children with and without family risk for dyslexia

This study examined language skills and pre-literacy skills (phonological awareness, rapid naming, and letter knowledge) before school-age as predictors of PISA reading at age 15 in two groups of children, with (n = 88) and without (n = 70) family-risk for dyslexia. Moreover, effects of family-risk on these early predictors, reading fluency, and PISA reading were examined while controlling the effect of gender. Children were followed from age 2 to 15. Family-risk had a significant effect on early language and pre-literacy skills, reading fluency and PISA reading. A similar model predicting PISA reading fitted the data well in the Family-risk and the No family-risk group. Language skills explained a good portion and pre-literacy skills to a lesser extent the variance in PISA reading. Altogether 68% of the variance in PISA reading was explained in the Family-risk group and 44% in the No family-risk group. Findings suggest that family risk sets children at elevated risk to develop long-standing difficulties in language and literacy and that the early language and pre-literacy skills are strong predictors of reading as far as PISA reading at age 15.

Pathways Into Literacy: The Role of Early Oral Language Abilities and Family Risk for Dyslexia

The present study investigated the role of early oral language and family risk for dyslexia in the two developmental pathways toward reading comprehension, through word reading and through oral language abilities. The sample contained 237 children (164 at family risk for dyslexia) from the Dutch Dyslexia Program. Longitudinal data were obtained on seven occasions when children were between 4 and 12 years old. The relationship between early oral language ability and reading comprehension at the age of 12 years was mediated by preliteracy skills and word-decoding ability for the first pathway and by later language abilities for the second pathway. Family risk influenced literacy development through its subsequent relations with preliteracy skills, word decoding, and reading comprehension. Although performance on language measures was often lower for the family-risk group than for the no-family-risk group, family risk did not have a specific relation with either early or later oral language abilities.