Related Factors Research Articles

PbrWRKY62-PbrADC1 module involves in superficial scald development of Pyrus bretschneideri Rehd.fruit via regulating putrescine biosynthesis

Putrescine plays a role in superficial scald development during the cold storage of pear fruit. However, the molecular mechanism behind this phenomenon has not been un-fully clarified until recently. In this study, a conjoint analysis of metabolites and gene expression profiles in the putrescine-metabolic pathway of P. bretschneideri Rehd. fruit followed by experimental validation revealed that PbrADC1, forming a homodimer in the chloroplast, was involved in putrescine biosynthesis and thus fruit chilling resistance. Additionally, the substrate-binding residue Cys546 in PbrADC1, whose activity was modified by H2O2, played a crucial role in arginine decarboxylation into agmatine. Through a combined analysis of the distribution of cis-acting elements in the PbrADC1 promoter as well as the expression profiles of related transcription factors (TFs), several TFs were identified as upstream regulators of PbrADC1 gene. Further investigation revealed that the nuclear PbrWRKY62 could directly bind to the W-box elements in the PbrADC1 promoter, activate its expression, enhance putrescine accumulation, and thus increase fruit chilling tolerance. In conclusion, our results suggest that the PbrWRKY62-PbrADC1 module is involved in the development of superficial scald in P. bretschneideri Rehd. fruit via regulating putrescine biosynthesis. Consequently, these findings could serve as valuable genetic resources for breeding scald-resistant pear fruit.Graphical

Uptake and detection rate of colorectal cancer screening with colonoscopy in China: A population-based, prospective cohort study

BackgroundColorectal cancer is the leading cause of cancer-related death worldwide. Colonoscopy is widely used as a screening test for detecting colorectal cancer in many countries. However, there is little evidence regarding the uptake and diagnostic yields of colonoscopy in population-based screening programs in countries with limited medical resources. ObjectiveWe reported the uptake of colonoscopy and the detection of colorectal lesions and explored related factors based on a colorectal cancer screening program in China. DesignIndividuals aged 45–74 years who were asymptomatic for colorectal cancer and had no history of colorectal cancer were recruited. An established risk score system was used to identify individuals at high risk for colorectal cancer, and they were subsequently recommended for colonoscopy. SettingA population-based, prospective cohort study was implemented in 169 communities, 14 districts of Chongqing, Southwest China. ParticipantsA total of 288,150 eligible participants were recruited from November 2013 to June 2021, and 41,315 participants were identified to be at high risk of colorectal cancer. MethodsGeneralized linear mixed model was used to explore the individual and community structural characteristics associated with uptake of colonoscopy. Additionally, the detection rate of colorectal lesions under colonoscopy screening was also reported, and their associated factors were explored. Results7859 subjects underwent colonoscopy, with an uptake rate of 19.02 % (95 % CI 18.64 %–19.40 %). Lower uptake rates were associated with older age, lower education, more physical activity, and structural characteristics, including residing in developing areas (OR 0.73, 95 % CI 0.69–0.78), residing more than 5 km from screening hospital (5–10 km: OR 0.85, 95 % CI 0.79–0.91; >10 km: OR 0.85, 95 % CI 0.80–0.91), and not being exposed to social media publicity (OR 0.63, 95 % CI 0.53–0.75). Overall, 8 colorectal cancers (0.10 %), 423 advanced adenomas (5.38 %), 820 nonadvanced adenomas (10.43 %), and 684 hyperplastic polyps (8.70 %) were detected, with an adenoma detection rate of 15.92 %. Several factors, including older age, male, current smoking and a family history of colorectal cancer, were positively related to colorectal neoplasms. ConclusionsThe uptake of colonoscopy for colorectal cancer screening was not optimal among a socioeconomically diverse high-risk population. The screening strategy should attempt to ensure equitable access to screening according to regional characteristics, and enhance the uptake of colonoscopy by recommended multifaceted interventions, which focus on individuals with poor compliance, select a closer screening hospital, and strengthen social media publicity at the structural level.

Analysis of related factors for RA flares after SARS-CoV-2 infection: a retrospective study from patient survey

SARS-CoV-2 and its variants are widely prevalent worldwide. With frequent secondary and breakthrough infections, immune dysfunction in RA patients, and long-term use of immune preparations, SARS-CoV-2 infection poses a significant challenge to patients and rheumatologists. Whether SARS-CoV-2 infection causes RA flares and what factors aggravate RA flares are poorly studied. A questionnaire survey was conducted on RA patients infected with SARS-CoV-2 after December 7, 2022, in China through a multicenter and inter-network platform regarding general personal condition, primary disease, comorbidity, SARS-CoV-2 vaccination, viral infection, and impact on the primary disease. A total of 306 RA patients were included in this study, and the patient data were analyzed, in which the general condition of RA patients, medication use before SARS-CoV-2 infection and post-infection typing and manifestations, and medication adjustment did not affect the Flare of RA patients after SARS-CoV-2 infection. The control of disease before SARS-CoV-2 infection (OR = 2.10), RA involving pulmonary lesions (OR = 2.28), and the recovery time of COVID-19 (OR = 2.50) were risk factors for RA flare. RA involving pulmonary lesions, control status of disease before infection, and recovery time of COVID-19 disease are risk factors for RA flare after SARS-CoV-2 infection.

Factors Affecting the Recruitment of Foreign Migrant Workers in Taiwan: A Case Study of Vietnamese Migrant Workers

Abstract The global development has led to a huge increase in the number of cross-border mobile employment, and many advanced industrialized countries have introduced cross-border migrant workers in order to continue their economic development. Taiwan began to introduce foreign migrant workers in 1989, and has since opened up various application qualifications and quotas for migrant workers in different sectors. By the end of 2022, there were about 228,000 Vietnamese industrial migrant workers in Taiwan, which was the largest number, accounting for 45% of the total number. Therefore, this study discusses the distribution of countries from which Taiwan imports foreign workers and the countries to which Vietnam exports workers, and compares and analyzes the relevant laws and policies of Taiwan government and Vietnamese government. In addition, issues related to migrant worker policies and human resources agencies are discussed through in-depth interviews with human resources agents and questionnaires on Vietnamese migrant workers in Taiwan. Although many past studies focused on foreign workers, in recent years, the demand for industrial workers has changed due to the pandemic, and Taiwan has faced low birth rate, aging and other factors, which has also impacted the labor supply in the job market. Under this situation, the problem of labor shortage may become more serious. Therefore, this study also analyzes the influence of pandemic and other related factors, hoping that the research results can provide references for related fields of industry, official and university. JEL classification numbers: E24, J21, J48. Keywords: Migrant worker policies, Human resources agencies, In-depth interviews.

Characteristics of tuberculosis in Marrakech (Morocco): Epidemiology and related factors

BackgroundTuberculosis remains (TB) a major public health problem; it is the first cause of death due to a single infectious agent, both for the world and the Moroccan population. In the city of Marrakech this infectious disease affected 853 cases in 2021 (Report of the Ministry of Health of Morocco). The aim of this paper is to investigate the epidemiology, diagnosis, evolution and associated factors of pulmonary tuberculosis compared to extra-pulmonary tuberculosis in Marrakesh city. MethodsA retrospective study was conducted between 2020 and 2021 on 240 patient's medical records with TB. FindingsPulmonary tuberculosis represented about half (49.58%) of the cases with a mean age of 37.17 (SD = 18.73) and a sex ratio (M/F) of 1.11. The age group most affected was 15–34 years (nearly 43% of the population). More than 23% of the patients were smokers and about 64% of them were not affiliated to any medical-social insurance. 19% of patients had a medical history in which diabetes predominated (46.2% of cases). Overall, only 58.9% of the patients had all the required medical check-ups and the weight decreased in 23% of the patients. Resistance to drugs was found in 9 cases and the HIV testing was positive in 4 cases. ConclusionsIn conclusion, enhancing population education and bolstering healthcare worker training are imperative for achieving early and effective diagnosis and monitoring of tuberculosis. Additional concerted efforts are needed on a national and international scale to address this pressing public health challenge.

Investigation of obesity and its related factors among Chinese medical staff: a cross-sectional pilot study

BackgroundMany studies have covered the prevalence of obesity in different populations. However, studies on the prevalence and predictors of obesity among medical staff are lacking. The aim of our study is to investigate the prevalence of obesity among medical staff and to identify the related predictors.MethodsUsing a snowballing recruitment strategy in the form of an electronic questionnaire, a cross-sectional survey was conducted among 1201 medical staff from cooperative hospitals between January and March 2022. We designed a questionnaire to investigate the participants’ demographic, lifestyle, diet, physical activity, and work status.ResultsThe overall prevalence of obesity was 8.5%, with males (13.7%) having a greater incidence than females (5.7%) (p < 0.001). Multiple logistic regression analyses showed that alcohol drinking (OR, 2.34; 95% CI 1.23–4.42, p = 0.01), sugar-sweetened beverages consumed > 3/week (OR, 2.50; 95% CI 1.02–6.15, p = 0.046), and working a night shift > 1/week (OR, 2.17; 95% CI 1.02–4.61, p = 0.043) were independent predictive factors for obesity in men. For women, having midnight snack having midnight snack (OR, 2.93;95% CI 1.24–6.96, p = 0.015), good sleep quality (OR, 4.47; 95% CI 1.10–21.70, p = 0.038), and working a night shift > 1/week (OR, 3.62; 95% CI 1.73–7.57, p = 0.001) were independently associated with obesity.ConclusionsObesity presented a low prevalence among medical staff. Alcohol drinking, drinking sugar-sweetened beverages > 3/week, and night shift > 1/week predicted a higher risk of obesity in males. In females, having midnight snack, good sleep quality, and night shift > 1/week were independently associated with obesity.Level of evidence: V, descriptive study.

Implementation of BRCA Test among Young Breast Cancer Patients in South Korea: A Nationwide Cohort Study.

This study aimed to investigate the frequency of BRCA testing and related factors among young breast cancer patients (age < 40 years) in South Korea. We conducted a nationwide retrospective cohort study using data from the Health Insurance Review and Assessment claims. Newly diagnosed breast cancer patients younger than 40 were included. Annual BRCA testing ratios (number of BRCA test recipients/the number of patients undergoing breast cancer surgery in each year) were analyzed by region and health care delivery system. We investigated the location of breast cancer diagnosis and BRCA testing. From January 2010 to December 2020, there were 25,665 newly diagnosed young breast cancer patients, of whom 12,186 (47.5%) underwent BRCA testing. The BRCA testing ratios increased gradually from 0.084 (154/1,842) in 2010 to 0.961 (1,975/2,055) in 2020. Medical aid (vs. health insurance) and undergoing surgery in metropolitan cities or others (vs. Seoul), general hospitals, and clinics (vs. tertiary hospitals) were associated with a lower likelihood of BRCA testing. While 97.8% of the patients diagnosed in Seoul underwent BRCA testing in Seoul, 22.9% and 29.2% of patients who were diagnosed in metropolitan areas and other regions moved to Seoul and underwent BRCA testing, respectively. The frequency of BRCA testing has increased over time in South Korea, with Seoul showing a particularly high rate of testing. About one-quarter of patients diagnosed with breast cancer outside of Seoul moved to Seoul and underwent BRCA testing.

Factors influencing health-related quality of life in women with endometriosis: A cross-sectional study.

This study aimed to assess the health-related quality of life and identify its associated factors in women with endometriosis. A cross-sectional correlation study design and convenience sampling were conducted in the gynecological outpatient clinic of a teaching hospital in northern Taiwan. A total of 216 women with endometriosis were recruited. The data were collected using structured questionnaires and analyzed using descriptive and inferential statistics. Participants reported a moderate level of health-related quality of life. The most significant impact of endometriosis on health-related quality of life was emotional well-being, followed by feeling of control or powerless, pain, social support, and self-image. Educational attainment, menstrual cycle, period length, perceived menstrual flow, symptom distress, and self-management strategies explained 66% of the variance in health-related quality of life. Factors influencing health-related quality of life in women with endometriosis play a key role in promoting women's well-being. Interventions based on these related factors should be developed and taken into practice to effectively manage the disease-related symptoms for women with endometriosis and thereby improve their overall health-related quality of life.

Clinical Outcomes and Medical Burdens of Neonatal Arrhythmias in Children's Hospitals in China: A Protocol for Multi-Center Retrospective Cohort Study.

Neonatal arrhythmias are significant contributors to infant mortality. Timely diagnosis and treatment are essential for neonates with non-benign arrhythmias to avoid severe complications, and ongoing treatment and follow-up are sometimes needed. The main objective of this study will be to understand the incidence and demographic characteristics of arrhythmias in hospitalized neonates in China and the related factors of outcomes. A secondary objective will be to establish the first follow-up system for neonatal arrhythmias in China. The medical burdens of neonatal arrhythmias in China will also be investigated. The data from the Futang Research Center of Pediatric Development (FRCPD) database between January 2016 and December 2021 were obtained. Newborns admitted to member hospitals with a discharge diagnosis of "neonatal arrhythmia" (ICD-10 code P29.151) or "arrhythmia" (ICD-10 code I49.904) were included. The medical record information was collected and classified into two groups: heart failure and non-heart failure. The differences between the two groups and independent risk factors for neonatal arrhythmias complicated with heart failure were analyzed. In addition, a follow-up study of patients discharged from Beijing Children's Hospital was conducted to evaluate their outcomes at the age of 3 years old. Factors influencing hospitalization costs were analyzed using rank-sum tests and multiple linear regression. It is anticipated that the study findings will provide new and comprehensive data on the health needs of neonatal arrhythmias in China. The study will establish the first follow-up system for neonatal arrhythmias in China. This study will help reduce the burden of patients and their families as well as the society.

Prevalence of Obsessive-Compulsive Personality Disorder in Medical Students

Objective: Obsessive-compulsive personality disorder (OCPD) is a cluster C personality disorder, and the most prevalent one. It is mainly characterized by perfectionism and can cause distress and functional impairment in the individual. This study aimed to determine the prevalence of OCPD in medical students, investigate the effect of this disorder on students’ academic performance, and discover any possible related factors.&#x0D; Methods: This cross-sectional observational study consisted of 508 medical students enrolled at the University of Jordan in 2021. It utilized a questionnaire that enquired about their sociodemographic information, academic information, and study habits. It also contained questions about the diagnostic criteria of OCPD from the fifth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5) and questions from the Personality Inventory for the DSM-5 (PID-5) to assess the presence of the rigid perfectionism personality trait.&#x0D; Results: Fifty-one percent of the studied sample either fulfilled the DSM-5 criteria or showed moderate or high expression of rigid perfectionism, according to the PID-5. More than two-thirds of the students able to be diagnosed with OCPD reported being overwhelmed with anxiety and stress at times of exams, and 41.5% stated that they skip sleep before exams even though they have finished studying.&#x0D; Conclusion: The reported prevalence of 51.18% in medical students is ten times the prevalence of OCPD in the general population. There was no association between OCPD and the students’ gender or academic performance. Students affected by OCPD seem to experience overwhelming amounts of stress and may need mental health support in the form of regular check-ups and counseling services.

Metabolome and Transcriptome Analysis Revealed the Basis of the Difference in Antioxidant Capacity in Different Tissues of Citrus reticulata 'Ponkan'.

Citrus is an important type of fruit, with antioxidant bioactivity. However, the variations in the antioxidant ability of different tissues in citrus and its metabolic and molecular basis remain unclear. Here, we assessed the antioxidant capacities of 12 tissues from Citrus reticulata 'Ponkan', finding that young leaves and root exhibited the strongest antioxidant capacity. Secondary metabolites accumulated differentially in parts of the citrus plant, of which flavonoids were enriched in stem, leaf, and flavedo; phenolic acids were enriched in the albedo, while coumarins were enriched in the root, potentially explaining the higher antioxidant capacities of these tissues. The spatially specific accumulation of metabolites was related to the expression levels of biosynthesis-related genes such as chalcone synthase (CHS), chalcone isomerase (CHI), flavone synthase (FNS), O-methyltransferase (OMT), flavonoid-3'-hydroxylase (F3'H), flavonoid-6/8-hydroxylase (F6/8H), p-coumaroyl CoA 2'-hydroxylase (C2'H), and prenyltransferase (PT), among others, in the phenylpropane pathway. Weighted gene co-expression network analysis (WGCNA) identified modules associated with flavonoids and coumarin content, among which we identified an OMT involved in coumarin O-methylation, and related transcription factors were predicted. Our study identifies key genes and metabolites influencing the antioxidant capacity of citrus, which could contribute to the enhanced understanding and utilization of bioactive citrus components.

Diagnostic value of abdominal ultrasound in patients with acute appendicitis and analysis of the expression of related inflammatory factors.

Appendicitis is an inflammation of the appendix that, if left un-treated, can be life-threatening. Abdominal ultrasound helps diagnose it and differentiate it from other causes of abdominal pain. This study aimed to evalu-ate the diagnostic value of abdominal ultrasound in acute appendicitis (AA) and assess inflammatory factor levels in different types of appendicitis. One hundred patients with AA were selected as the observation group, and 30 pa-tients with simple abdominal pain as the control group. Among the 100 AA patients, 37 (37%) cases had blurred appendiceal boundaries, 24 (24%) cases had fecal calculus in the appendix cavity, 13 (13%) cases had enhanced echo intensity of surrounding fat, 15 (15%) cases presented enlarged outer diameter of the appendix (&gt; 6mm), one (1%) case had peripheral lymphadenopathy, and one (1%) case had peripheral effusion. None of the cases (0%) presented a pe-ripheral mass. The levels of white blood cells (WBC) and inflammatory factors: C-reactive protein (CRP), interleukin-6 (IL -6), and tumor necrosis factor α(TNF-α)) patients with uncomplicated appendicitis were lower than those with suppurative appendicitis, gangrenous appendicitis, or peri-appendiceal abscess (p &lt;0.05). The blurred boundary of the appendix, fecal stones in the appendix cavity, an enlarged outer diameter of the appendix (&gt; 6mm), and an enhanced echogenicity of the surrounding fat are the most common ultrasonic signs of AA. Abdominal ultrasound has an excellent diagnostic value on pathological types of AA. The increase in the level of inflammatory factors can indicate the severity of the disease to a certain extent.

Features of different asset types and extreme risk transmission during the COVID-19 crisis

Unlike the current extensive literature, which discusses which assets can avoid the risks caused by the COVID-19 pandemic, this study examines whether the characteristics of different assets affect the extreme risk transmission of the COVID-19 crisis. This study explores the effects of COVID-19 pandemic–related risk factors (i.e., pandemic severity, pandemic regulations and policies, and vaccination-related variables) on the risk of extreme volatility in asset returns across eight assets. These eight assets belong to the following classes: virtual, financial, energy, commodities, and real assets. To consider the different possible aspects of the COVID-19 impact, this study adopts both empirical methods separately, considering variables related to the pandemic as exogenous shocks and endogenous factors. Using these methods, this study enabled a systematic analysis of the relationship between the features of different asset types and the effects of extreme risk transmission during the COVID-19 crisis. The results show that different types of asset markets are affected by different risk factors. Virtual and commodity assets do not exhibit extreme volatility induced by the COVID-19 pandemic. The energy market, including crude oil, is most affected by the negative impact of the severity of the pandemic, which is unfavorable for investment at the beginning of the pandemic. However, after vaccinations and pandemic regulations controlled the spread of infection, the recovery of the energy market made it more conducive to investment. In addition, this study explains the differences between the hedging characteristics of Bitcoin and gold. The findings of this study can help investors choose asset types systematically when faced with different shocks.

The correlation between CT perfusion deficits and immediate post-endovascular treatment contrast extravasation on dual energy CT in acute ischemic stroke patients

PurposeAfter endovascular therapy (EVT) for ischemic stroke, post-EVT CT imaging often shows areas of contrast extravasation (CE) caused by blood brain barrier disruption (BBBD). Before EVT, CT-perfusion (CTP) can be used to estimate salvageable tissue (penumbra) and irrevocably damaged infarction (core). In this study, we aimed to correlate CTP deficits to CE, as a surrogate marker for BBBD, after EVT for ischemic stroke. MethodsIn this single center study, EVT patients between 2010 and 2020 in whom both CTP at baseline and DECT post-EVT was performed were included. The presence of core and penumbra on CTP was assessed per ASPECTS region, resulting in a CTP-ASPECTScore and a CTP-ASPECTScore+penumbra. Likewise, CE on DECT was scored per ASPECTS region, resulting in a CE-ASPECTS. Correlation was assessed using Kendall’s tau correlation and positive predictive values (PPV) were calculated per ASPECTS region. Bland-Altman plots were created to visualize the agreement between the two scores. Results194 patients met our inclusion criteria. The median core and penumbra were 8 cc (IQR 1–25) and 103 cc (IQR 68–141), respectively. The median CTP-ASPECTScore, CTP-ASPECTScore+penumbra, and CE-ASPECTS were 7 (IQR 4–9), 3 (IQR 1–4), and 6 (IQR 4–9), respectively. The correlation between CTP-ASPECTScore and CE-ASPECTS was τ = 0.21, P <.001, and τ = 0.13, P =.02 between CTP-ASPECTScore+penumbra and CE-ASPECTS. Bland-Altman plots showed a mean difference (CTP-ASPECTS minus CE-ASPECTS) of 0.27 (95 %CI −6.7–7.2) for CTP-ASPECTScore and −3.2 (95 %CI −9.7–3.2) for CTP-ASPECTScore+penumbra. The PPVs of the CTP-ASPECTScore and CTP-ASPECTScore+penumbra were highest for the basal ganglia. ConclusionThere is a weak although significant correlation between pre-EVT CTP-ASPECTS and post-EVT CE-ASPECTS. The weak correlation may be attributed to various imaging limitations as well as patient related factors.

The pathogen Vibrio alginolyticus H1 and its antagonist Pseudoalteromonas piscicida H2 associated with the health status of cuttlefish Sepia pharaonis

The balance in bacterial community is very important for the maintenance of the health status in the hosts. During the occurrence of a pervasive skin ulcer disease in Sepia pharaonis, bacterial isolate H1 and its antagonist bacterial isolate H2 were simultaneously isolated from the healthy cuttlefish, but only bacterial isolate H1 was isolated from the diseased cuttlefish. In the present study, the genetic and biochemical analysis showed that isolate H1 was identified as Vibrio alginolyticus, and isolate H2 was identified as Pseudoalteromonas piscicida, respectively. The antibiotic susceptibility test using CLSI M45–2015 method showed that the antibiotic resistance of V. alginolyticus H1 and P. piscicida H2 was different, and V. alginolyticus H1 showed strongly resistance to ampicillin. LD50 was calculated based the infection using immerse infection experiment. The result showed that the LD50 for 7 d of V. alginolyticus H1 was 1.58 × 106 CFU/mL, while the no death was observed during the infection of P. piscicida H2. Since the virulence related factors were significantly influenced by host immunity, the virulence factors of pathogen V. alginolyticus H1 was assessed under the stressors of H2O2 and 2,2′-dipyridyl. The results showed that the pathogenicity of V. alginolyticus H1 was associated with the haemolytic activity and bacterial motility. Different components of the P. piscicida H2 were collected and were tested for the antagonistic activity. It was unexpected that no antagonistic substance was detected, while V. alginolyticus H1 showed obvious phobotaxis to P. piscicida H2. It could be concluded that V. alginolyticus H1 was a pathogen of S. pharaonis, and P. piscicida H2 was a potential antagonistic bacteria to inhibit V. alginolyticus H1 via chemotaxis instead of producing antagonistic substance.

Cultural, Psychosocial, and Educational Factors in Relation to Ethnic Identity among Cambodian High School Students in the United States

Cultural, Psychosocial, and Educational Factors in Relation to Ethnic Identity among Cambodian High School Students in the United States

Linkages between Workplace Aggression and Organizational Environment: A Study of Non-academic Staff in the University of Ibadan, Nigeria

Aggression is an emotional behaviour that causes feelings of hostility. It can be internally or externally triggered; displaying violence action that is hostile to the subjects. The problem of aggression is that sometimes, it can be in action without externally provoked. and has the capacity of disrupting interpersonal relationships and work productivity. Thus, the study was carried out to develop and validate Workplace Aggression Scale for assessing Linkages Between Workplace Aggression and Organizational Environment: A Study of Non Academic Staff University of Ibadan, Nigeria. Three research objectives, 4 questions with 2 hypotheses were used. The population of the study includes all the staff of Education. Sample size was 30(15males and 15females) respondents. Design was Correlation Survey Descriptive Design and Stratified Purposive Sampling. Workplace Aggression Assessment Scale (WAAS) is a new construct scale that was developed by the researcher for determining aggression at workplace. It is in its first time self scale for assessing the aggression on the workplace. The scale with five points from 1-5 tested both work environment and personality factors using 20- items scale. 1 indicates (Always) and 5 indicate (Never). The 20 items measured Internal Consistence of the factors and obtained Cornbach Alpha PE (.748) and EN (.799) summed as (.774). It was discovered that WAAS contents can be used for other related factors like stress and anxiety at work. The data was analyzed using SPSS. The findings of the research revealed that Personality and Environment (X = 1.8, SD= 0.33); T-value (t-test=17.03, t-crit= 1.73, p= .000&lt;0.05); S.M.E.(3.20); Variance (107.9); Skewness (0.519); SK.S.E (0.689); Kutosis (-0.149) and K.S.E (1.339) were all accepted as perceived determinants factors for workplace aggression on Linkages Between Workplace Aggression and Organizational Environment: A Study of Non Academic Staff in the, University of Ibadan, Nigeria. Based on the findings, the study recommended that counseling services should be highly considered in every institution of human beings if the issues of workplace aggression must be addressed.

Analysis of BDS inter-satellite link ranging performance

The Ka-band inter-satellite link (ISL) is a key technology of BeiDou Global Navigation Satellite System (BDS-3) that can improve the system performance. Based on 30 days of ISL observations, we analyze the BDS-3 ISL ranging performance and the related influencing factors, such as satellite manufacturer, satellite orbit type and link type. The fitting residuals of the ISL geometry-free observations are used to characterize the measurement noise, and the post-fit ISL residuals from precise orbit determination (POD) and precise clock estimation (PCE) are used to further validate the ranging performance. The fitting residuals follow a normal distribution, and the average root mean square (RMS) value for all 421 links is approximately 2.5 cm. The satellite manufacturers, China Academy of Space Technology (CAST) and Shanghai Engineering Center for Microsatellites (SECM), have an obvious impact on the ISL measurement noise. The RMS of the ISL fitting residuals for the links established by the two CAST satellites is only 1.45 cm, while it can reach 3.34 cm for the links established by the two SECM satellites. This correlation between ISL ranging performance and the satellite manufacturer is also found in the POD and PCE post-fit ISL residuals. The RMS of PCE residuals is about 3.1 cm, while the POD residuals are larger with the RMS of 5.5 cm due to the effect of orbital errors, especially for the Inclined Geosynchronous Orbit (IGSO) and Geostationary Orbit (GEO) satellites. Overall, the ranging accuracy of the BDS-3 ISL is better than 5 cm according to the above analyses. Furthermore, the BDS-3 satellite orbit and clock results are evaluated by internal consistency check and external comparison to analyze the application of ISL observations.

Natural course of post-COVID symptoms in adults and children

More than 200 million COVID-19 survivors have lasting symptoms after recovering, but the duration and related risk factors remain uncertain. This study focused on all 6551 patients diagnosed with COVID-19 at a medical institution in Hiroshima from March 2020 to July 2022. In November 2022, a questionnaire survey was conducted regarding post-COVID symptoms and their duration. The prevalence and duration of post-COVID symptoms were illustrated using the Kaplan–Meier method. Risk factors for symptoms lasting over 3 months and interfering with daily life were assessed via multivariate logistic regression. A total of 2421 survivors responded: 1391 adults, 1030 children, median age 34 years (IQR 9–55), 51·2% male, 36·7% hospitalized, median time from infection to the survey was 295 days (IQR 201–538). Upon their initial recovery, the prevalence of post-COVID symptoms was 78·4% in adults and 34·6% in children. Three months later, the rates were 47·6% and 10·8%. After over one year, they were 31·0% and 6·8%. Regarding symptoms interfere with daily life, 304 people (12.6%) experienced symptoms lasting for over three months, with independent risk factors including age, being female, diabetes mellitus, infection during the Delta period, and current smoking. There was no significant association between vaccination history and post-COVID symptoms.

Treatable mortality and health care related factors across European countries.

Despite the improvements in European health systems, a large number of premature deaths are attributable to treatable mortality. Men make up the majority of these deaths, with a significant gap existing between women and men's treatable mortality rate in the EU. This study aims to identify the healthcare-related factors, including health expenditures, human and physical resources, and hospital services use associated with treatable mortality in women and men across European countries during the period 2011-2019. We use Eurostat data for 28 EU countries in the period 2011-2019. We estimate a panel data linear regression with country fixed effects and quantile linear regression for men and women. The results found (i) differences in drivers for male and female treatable mortality, but common drivers hold the same direction for both sexes; (ii) favorable drivers are GDP per capita, health expenditures, number of physicians per capita, and (only for men) the average length of a hospital stay, (iii) unfavorable drivers are nurses and beds per capita, although nurses are not significant for explaining female mortality. Policy recommendations may arise that involve an improvement in hospital bed management and the design of more specific policies aimed at healthcare professionals.