It is evident that health workers, particularly nurses, are more susceptible to burnout. This study aims to determine the relationship between Grit and burnout and the function of extroverted personality types in nurses as moderators. The measuring instruments used in this study were the Burnout, Grit scale, and Eysenck personality questionnaire The sample of this study amounted to 130 respondents with a simple random sample collection technique. The respondent was an inpatient nurse at one of the teaching hospitals in Gresik with the criteria for a bachelor's and a diploma in nursing Ners. Quantitative analysis in this study uses moderated regression analysis method for hypothesis testing. The results showed that the first hypothesis was accepted (sig<0.05) that there was a negative relationship between Grit and Job Burnout in nurses. The higher the grit of the individual, the lower the burnout. The results of the analysis also showed that the second hypothesis was rejected (sig>0.05). The extroverted personality type possessed by nurses does not moderate the relationship of grit with job burnout, but the extroverted personality type can be used as a predictor variable of the burnout experience.