Extraskeletal Chondroma Research Articles

Benign extra skeletal chondroma of the tongue in a 16-year-old female

Chondromas are tumors that result from chondroid differentiation most frequently occurring in areas where chondrocytes are present. Rarely, they can present in soft tissues, such as the tongue. This case report will review the extra skeletal chondroma found on the posterior tongue of an asymptomatic 16-year-old female. Discussed within this case report will include the importance of histopathological analysis in distinguishing enchondroma versus chondrosarcoma and review the malignant transformation rate. Additionally, it will compare the trends of chondromas found in the oral cavity that have been previously published. This case will highlight the importance of recognizing chondromas in unusual places, such as the origin of soft tissues, and emphasize the importance of early diagnosis, surgical intervention and providing optimal outcomes for young patients.

Extra skeletal chondroma a rare presentation in the big toe of a pediatric patient: a case report

Extra-skeletal chondroma is a rare benign tumor of juxta-articular soft tissues rarely seen in pediatric cases. It is formed mainly of hyaline cartilage and presented as a painless swelling. It is not well evident on conventional X-rays radiography. MRI is the preferred diagnostic modality. Surgical excision is the recommended form of treatment for symptomatic cases. We are reporting a case of this rare tumor in the big toe of a child.

A Rare Soft Tissue Tumor Confused Radiologically with Chondroma; Extraskeletal Osteosarcoma

Extraskeletal osteosarcoma is a malignant chondro-osseous neoplasia that is not associated with the skeletal system. It accounts for less than 1% of all soft tissue sarcomas. We report a case of a 60-year-old male with an isolated primary subcutaneous tumor in the dorsal aspect of his left foot. The lesion was initially considered an extraskeletal chondroma radiologically. After imaging; surgical excision and pathological analysis the diagnosis of extraskeletal osteosarcoma was made. This report includes the clinical and pathological findings of extraskeletal osteosarcoma in this case.

Case of Chondroma in Prepubic Space: A Rare Occurrence

The pelvic bone can be affected by a various diseases, including tumours. Cartilaginous tumours may develop in this area because it contains hyaline and fibrocartilage. The pelvis is known to host malignant tumours like chondrosarcoma. On the other hand, chondroma, a benign cartilaginous tumour, is occasional. Chondroma is known to occur in different osseous and extraosseous locations. Extraskeletal/soft-tissue chondroma, though rare, is known for its occurrence in various anatomical locations. Hereby, the authors present a case report of a chondroma in the prepubic space that manifested with urinary symptoms. A 58-year-old female, known to be diabetic, came with acute urinary retention. She experienced a recent onset of burning micturition and abdominal pain. Radiological and cytological findings were non diagnostic. During pelvic exploration, a solid mass of 3×3 cm was noted in the prepubic space without a connection to the urinary bladder or underlying bone. Excisional biopsy of the mass showed benign mature chondrocytes in a background of chondroid matrix, suggesting a benign cartilaginous tumour (chondroma). The patient is now free of her symptoms and is doing well during the follow-up at three months. Authors could not find any case reports of chondroma in the prepubic space in the literature. The present case of extraskeletal chondroma in the prepubic space is an infrequent entity at an unusual site.

Extra skeletal chondroma in 11 years old female at flexor tendon sheath of right middle finger, rare presentation: Case report

Extra skeletal chondroma in 11 years old female at flexor tendon sheath of right middle finger, rare presentation: Case report

A Clinical Case of Comorbid Adenocarcinoma of the Upper Lobe of the Left Lung and Chondroma of the Diaphragm

The article describes a clinical case of comorbid peripheral lung cancer and extraskeletal chondroma of the diaphragm detected in the patient during chest computed tomography performed as a part of examination after renal colic. The X-ray signs of the masses were completely different, and those lesions were immediately identified as two different pathologies.

Extraskeletal Intramuscular Chondroma of the Knee - Case Report and Review of the Literature.

Extraskeletal chondromas are small nodular cartilaginous lesions not attached to bone or the periosteum. They are rare tumors commonly occurring in the hands and feet. The objective of the present study is to describe a case of extraskeletal intramuscular chondroma (EIC) in the left knee and the diagnostic challenges faced by us. A 25-year-old female patient presented with slow-growing swelling in the left knee for 2 years. Clinically, the swelling was arising from the quadriceps muscle. We considered possibilities such as rhabdomyoma, neurofibroma, and intramuscular lipoma. Imaging studies suggested a benign fatty tumor. She was treated by excision. Microscopy was consistent with EIC without recurrence. A rare entity, clinically, EIC can mimic other benign soft-tissue tumors. Histopathology exams can provide a definitive diagnosis. The excision of the tumor is curative.

Chondromas and multiple enchondromatosis

Introduction The chondromas are a cartilaginous proliferation of mature appearance and moderate size, reason why these tumors are regarded more like hamartomas than real benign tumor. Chondromas represent 10 to 12 % of benign bone tumors. Any bone of an enchondral ossification may be involved. Several bones can be involved, and the disease is called “chondromatosis”. In the review we describe clinical and radiological findings of this pathology as well as indications for reconstructive surgery. Material and methods The review is dedicated to isolated chondromas, periosteal and extraskeletal chondromas, chondromatosis. Results The aspects of epidemiology, clinical presentation, radiology, MRI, prognosis, indications and methods of surgical treatment have been described in the article for each types of chondroma and enchondromatosis. Conclusion Chondromas are benign bone tumors which may be responsible of pathologic fractures. Their surgical treatment consists in curettage and bone grafting or bone-cement filling with or without osteosynthesis. Multiple enchondromatosis should be considered as an osteochondrodysplasia. Its treatment is not the treatment of the multiple chondromas themselves, but of the bone deformities and length discrepancy induced by the disorder. The transformation of some tumors in chondrosarcomas in adolescence or adulthood needs a strict follow up of these patients.

Target-like chondrocytes with thick perichondrocytic rings in cartilage-forming tumours. Preliminary report.

Here we present our experience with the occurrence of neoplastic chondrocytes with target-like appearance surrounded with unusual hypertrophic thick eosinophilic perichondrocytic rings (baskets), sometimes containing two or several layers. Pericellular rings (baskets) were positive in APAS and Masson's staining method and showed immunoreactivity with antibody against type IV collagen. Such single cells or small groups of such cells were observed rarely in 3 osteochondromas, 2 skeletal chondromas, 2 extraskeletal chondromas and 2 skeletal and 1 laryngeal chondrosarcomas. Moreover, 1 unusual soft tissue chondrosarcoma was composed entirely of target-like chondrocytes with hypertrophic extremely thick perichondrocytic rings. Such cartilage-forming tumour with target-like cells, which, to the best of our knowledge, is the first such chondrosarcoma reported in the literature. Ultrastructural evidence is presented that perichondrocytic rings have complicated structure.They contained microfibrillar component with abundant admixture of irregular aggregates of dense amorphous non-fibrillar material localised in lacunar spaces. In outer part of the rings predominated microfibrillar structures corresponding to type VI collagen that produced a rather dense capsule-like demarcation line against surrounding intercellular spaces. The described unusual changes are probably the result of hyperproduction and remodelation of perichondrocytic matrix by abnormal neoplastic chondrocytes in response to unknown factors. Local vascular and molecular signals, may be supposed as probable causes of this phenomenon.

Extraskeletal Chondroma of the Fallopian Tube; An Incidental Finding During LSCS in 32 Years Old Female

Extraskeletal chondroma (also known as ”Chondroma of soft parts”) is a cutaneous condition, a rare benign tumor of mature cartilage usually occurs in the hands, feet, head and neck. This tumor regularly presents as a small solitary nodule. The histogenesis of the cancer is controversial, but some have suggested a metaplastic origin. Chondroma of the fallopian tube is very rare. There are only three case reports in English literature. The source of this tumor can be subcoelomic mesenchyme of the tubal serosa or mesenchyme of the mesosalpinx. We describe a case of chondroma arising from the serosal surface of the fallopian tube with a review of the literature. A 30-yr-old woman with term pregnancy visited the hospital for cesarean section and tubal ligation. On operating findings, 1 1.5 cm sized nodular mass was noted in the left tubal serosal area. The excised mass showed a multilobulated appearance covered with a thin fibrous membrane. The cut surface was solid, grayish-yellow, and myxoid with a focal gelatinous area. The microscopic finding showed islands and elongated lobules of mature benign cartilage.

Extraskeletal Chondroma Resulted in Restriction of Range of Motion of the Forearm

Extraskeletal Chondroma Resulted in Restriction of Range of Motion of the Forearm

Intrakapsularni i paraartikularni hondromi kolena - prikazi slučaja

Introduction: Intracapsular and Para-articular chondroma is a rare variant of the extraskeletal chondromas. It arises from the capsule and/or the para-articular connective tissue of the large joints (mostly the knee) and is a result of cartilaginous metaplasia. In the course of time these tumors ossify and this is where their second name comes from: Para-articular osteochondromas. Case reports: We report six new cases of para-articular chondroma of the knee. On physical examination there was slow-growing solid mass in the knee and moderate pain. The radiological findings and CT scan show soft-tissue mass with variable amount of ossification, and on histological examination the presence of mature hyaline and connective cartilage was confirmed in all of the cases. Conclusion: The diagnosis of these benign tumors is made with correlation of clinical, radiological and histological features. Treatment of choice is surgical excision.

A case of extraskeletal chondroma of the second toe

A case of extraskeletal chondroma of the second toe

Excision of a Chondroma from the Plantar Foot Accompanied by Application of an External Continuous Tissue Expander to Facilitate Wound Closure: A Case Report

Extra skeletal chondromas, also known as chondromas of the soft parts, are benign cartilaginous tumors which can arise de novo from soft tissue. They are extremely rare with a predilection for the extremities, particularly the hands and the feet. A review of the published data reveals ample literature highlighting the recognition and management of these kinds of tumors involving the sole of the foot. However, there is limited data addressing the facility of wound closure in the presence of a large soft tissue defect that can potentially be the result of tumor excision. We discuss our findings in the context of a case of a 70 year old male, who presented with such an anomaly involving the plantar aspect of his right foot. Biopsy of the lesion prior to surgery was consistent with a chondroma. We present a dual approach to treatment of this condition involving both the excision and simultaneous wound revision process by utilizing a Derma Close® tissue expander. With the aid of this device, we were able to excise the soft tissue mass and primarily close our surgical site by minimizing the tension at the wound edges.

A rare case of para-articular chondroma of the hip joint in an adolescent

Extraskeletal chondromas are unusual benign skeletal tumors which do not arise from the bone or perisoteum. They are predisposed to occur in adults usually around the knee joint. We report a rare form of Extraskeletal chondroma arising from the outer layer of the capsule of the hip joint in an adolescent male which was excised surgically and it turned out to be a para-articular chondroma of the hip joint. In conclusion, ESPAOC lesions are extremely rare. It requires a thorough clinical examination and radiographic investigation to diagnose these tumors. The treatment is surgical excision of the tumor mass. A total excision might not be possible in all patients such as ours. In these cases, the part of the tumor causing symptomatic disconcern might be excised to allow functional range of movements of the affected joint.

Soft tissue chondroma: a rare tumor presenting as a cutaneous nodule

Soft tissue chondroma (STC), also known as extraskeletal chondroma or chondroma of soft parts is a benign cartilaginous tumor which arise de novo from soft tissue. Also, it is an extremely rare entity predominantly involving extremities, especially fingers. A 26 year old male presented with 3 year history of swelling in left index finger. On local examination a hard 2 × 2 cm swelling was seen over the volar aspect of left 2nd proximal phalanx. Swelling was mobile on contraction of tendons. X-ray showed a soft tissue shadow on volar aspect of left second proximal phalanx. Histopathology showed a well encapsulated, hypo cellular nodule composed of benign chondrocytes surrounded by hyaline chondroid matrix. Nuclear pleomorphism, mitosis or necrosis was not seen. Based on radiological and histopathological findings a diagnosis of STC was made. STC should be considered in patients with slow growing, soft tissue masses.

A case of extraskeletal chondroma of the temporomandibular joint capsule

Extraskeletal chondromas are rare benign cartilaginous tumors. Clinically, these tumors are most frequently found in the hands and feet. However, it is extremely rare for them to develop in the oral and maxillofacial regions. We present the case of a 50-year-old man with a tumor lesion of the temporomandibular joint capsule, which is a site that has not been described previously. Based on the physical examination and imaging study, the tumor was located in the joint capsule, and it was locally excised and pathologically diagnosed as extraskeletal chondroma. Postoperatively, residual disability and tumor recurrence were not observed.

A Case of Extra-Skeletal Intracranial Chondromass: Ultrastructure and Immunohistochemical Features

The discrete microvasculature environment of the perivascular plays a dominant role in regulating stem cell activity and its proliferation behavior. Mesenchymal stem cells (MSC) reside in perivascular compartment, hence have the potential to contribute to the pathogenesis of extra-skeletal intracranial chondroma (ESICC). In this case report, for the first time, the immunohistochemical (IHC) markers and transmission electron microscpoe (TEM) features of perivascular are presented in ESICC. Microscopic examination revealed a well-differentiated chondroma with foci of ossification and islands of vacuolated-cells encircling thin-walled capillaries. TEM showed transitional morphological features suggestive of transformation to chondrocytes, with vacuolated cells. A subpopulation of spindle vacuolated-cells displayed reaction for S-100, ferritin, trypsin-anti-chymotrypsin and Vimentin. As there was no evidence of transitional forms to arachnoid cells, it can be concluded that the origin of the recognized ICC is a perivascular multipotential mesenchymal cell, MSC.

Extraskeletal Osteochondroma of the Heel: A Case Report

Osteochondroma is the most common benign bone tumor and usually occurs in the metaphyseal region of the long bones around the knee. This is acartilage-capped bony tumor, which out growths on the surface of the bone. Extraskeletal osteochondroma is a variant of extraskeletal chondromas that are uncommon soft-tissue cartilaginous tumors. This report describes thecase of a 56-year-old woman with an extraskeletal osteochondroma of the heel.

Chondroma of the diaphragm mimicking a giant liver tumor with calcification: report of a case

Extraskeletal chondroma is an unusual benign tumor, which rarely arises in the diaphragm. We report a case of chondroma of the diaphragm in a 31-year-old woman. Initially, a benign liver tumor with calcification was suspected, based on pre and intraoperative examination findings. Although parts of the tumor were contiguous with the diaphragm, its connections with the diaphragm were much narrower than its connection with the liver, which suggested a liver tumor. Pathological examination subsequently revealed that the chondroma was contiguous with the diaphragm and that there was a distinct border between the tumor and the liver; thus, the tumor was diagnosed as a chondroma of the diaphragm.