Extra Devices Research Articles

Wideband Transmissive Programmable Metasurface for Adaptive Millimeter‐Wave Beamforming

AbstractProgrammable metasurfaces provide a promising paradigm for the beamforming of electromagnetic waves in the fifth‐generation (5G) and sixth‐generation (6G) wireless communications with low cost and low complexity. However, most of the existing researches are focused on the sub‐6 GHz spectrum, which limited the gigabits per second (Gb s−1) high‐speed data transmission on future wireless network. Additionally, as a step forward in the development of intelligent metasurfaces, extra peripheral devices are often required to sense environmental variations for self‐adaptive modulations. Here, a wideband millimeter‐wave programmable metasurface is presented for peripheral‐free self‐adaptive signal enhancement in 5G/6G wireless communication. The proposed transmissive programmable metasurface consists of meta‐atoms, exhibiting efficient transmission (1 dB loss) and a stable 1‐bit phase difference from 23.7 to 32.1 GHz, effectively covering the desired 5G millimeter‐wave frequency bands: N257, N258, and N261. By integrating the self‐adaptive algorithm based on received signal intensity into the controller, the programmable metasurface can self‐adaptively establish an optimal or acceptable channel according to the predefined threshold values. To evaluate the performance of the prototype, an experiment on wavefront modulation was first conducted in a microwave chamber, verifying the wideband beamforming performance of the programmable metasurface. Moreover, self‐adaptive signal enhancement and millimeter‐wave wireless communication experiments were conducted in indoor environments, showing a maximum signal enhancement of 21.4 dB and a significant improvement in constellation. The proposed self‐adaptive wideband programmable metasurface demonstrates high potential for application in 5G/6G millimeter‐wave wireless networks.

Comparative Evaluation of Condylar Guidance Obtained by Digital Panoramic Radiographic Images Using Two Different Interocclusal Recording Material During Jaw Relation in Completely Edentulous Patients: An In Vivo Study.

Objective To compare the condylar guidance value obtained during jaw relation by two different interocclusal recording materials to that obtained from OPG (Orthopantomogram). Materials and methods Two different interocclusal recording materials were used, namely bite registration wax (reinforced wax, by MAARC Dental Company) and bite registration paste (jet bite, coltene) for interocclusal records during jaw relations. An OPG is shot prior to the treatment, and horizontal condylar guidance (HCG) is traced joining the bony landmarks in a completely edentulous patient seeking complete denture treatment. All the conventional steps for complete denture fabrication up to jaw relation are performed. A facebow transfer is done on a Hanau H2 articulator, and height tracers (extra oral tracing devices) are attached. After satisfactory training, the tracing is performed by the patient, and the interocclusal records are obtained. The articulator is programmed to obtain the value of HCG using protrusive records, which are then compared to the value obtained from OPG. Statistics were carried out to determine angles. Followed by statistical analysis with Pearson correlation to analyze the results (α = 0.01). Results A substantial relationship was discovered between the horizontal condylar inclination between two interocclusal recording materials and the corresponding OPG for both the right (p = 0.0015) and left (p = 0.0007) sides. Conclusion The condylar guidance obtained with jet bite was closer than the condylar guidance value obtained with reinforced wax when compared with the horizontal condylar inclination obtained in OPG by tracing with a mean difference of 10° for polyvinyl siloxane and 20° for reinforced wax in seven subjects evaluated.

Substrate-Switched Dual-Signal Self-Powered Sensing System Based on Dual-Nanozyme Activity of Bimetal-Doped CeO2 Nanospheres for Electrochemical Assay of Aflatoxin B1.

The long-term operation feature of enzymatic biofuel cell-based self-powered biosensor (EBFC-SPB) endows them with the potential to execute dual-signal biosensing without having to integrate an extra signal acquisition device. Herein, cobalt and manganese codoped CeO2 nanospheres (CoMn-CeO2 NSs) with glucose-oxidase-like and peroxidase-like activities have been developed as substrate-switched dual-channel signal transduction components in EBFC-SPB for a dual-signal assay of aflatoxin B1 (AFB1). The CoMn-CeO2 NSs modified with aptamer are anchored to a complementary DNA-attached bioanode of EBFC-SPB by base complementary pairing, which catalyze the glucose oxidation together with the glucose oxidase (GOx) on the bioanode. Once the AFB1 appears, CoMn-CeO2 NSs will be released from the bioanode due to the binding specificity of the aptamer, resulting in a decreased catalytic efficiency and the first declining stage of EBFC-SPB. Accompanied by the introduction of H2O2, the residual CoMn-CeO2 NSs on the bioanode switch to peroxidase-like activity and mediate the production of benzo-4-chlorohexadienone (4-CD) precipitate, which increases the steric hindrance and yields another declining stage of EBFC-SPB. By assessing the variation amplitudes during these two declining stages, the dual-signal assay of AFB1 has been realized with satisfying results. This work not only breaks ground in dual-signal bioassays but also deepens the application of nanozymes in EBFC-SPB.

Suppressing harmful defects to enhance the performance of kesterite solar cells via extra Mg-doping

Extra-cations doping is known to be an effective approach to control the generation of harmful defects and band-tail states in Cu2ZnSn(S, Se)4 (CZTSSe) solar cells. Here, Mg is used as the extra doped element candidate, the impact of its doping concentration on the composition, structure, morphology, electrical properties, and efficiency of CZTSSe devices is systematically investigated, and its optimal doping concentration is 2 %, which can improve the efficiency of devices from 7.08 % to 9.0 %. The remarkably improved efficiency of the extra Mg-incorporated devices can be explained by the better crystalline quality and fewer deep defects. This work can provide a new approach to boost the performance of kesterite solar cells.

Effects of hydrogen and methane anti-knocking characteristics on the efficiency and power output in argon power cycle engines

Argon Power Cycle (APC) combustion engine has a high efficiency, zero carbon emissions, and zero pollutant emissions, rendering it a promising way for achieving zero or carbon neutrality within the realm of internal combustion engine (ICE) technology. Previous studies have shown that while APCs significantly improve the thermal efficiency of ICEs, they also face serious knock problems due to their high temperatures and pressures, especially when hydrogen is used as a fuel. In this study, the anti-knocking characteristics of hydrogen, methane, carbon monoxide, and ammonia were first investigated in APC through thermodynamic calculations by Ignition Delay Time. Then, based on testbench experiments, hydrogen and methane fuels were selected to further investigate the effect of different fuel anti-knocking characteristics on the indicated thermal efficiency and power of APC combustion engine. Test results showed that when using hydrogen, the APC ICE exhibited a pronounced knock tendency, and the test engine could not operate stably when the excess oxygen ratio <2.1 at compression ratio = 9.6. The CA50 of the maximum efficiency point was delayed in APC than in air for both hydrogen and methane, specially H2 has an obvious lag at about 5–15 ° CA. In comparison, when using methane, the combustion control of engine is easier, and the peak indicated thermal efficiency 59% and the peak indicated mean effective pressure 0.92 MPa are higher than 54.3% and 0.60 MPa of using hydrogen. The use of hydrogen still needs an anti-knocking strategy while an extra carbon capture device is necessary to ensure a closed argon cycle if methane is employed.

Benchmarking parallel programming for single-board computers

Within the computing continuum, SBCs (single-board computers) are essential in the Edge and Fog, with many featuring multiple processing cores and GPU accelerators. In this way, parallel computing plays a crucial role in enabling the full computational potential of SBCs. However, selecting the best-suited solution in this context is inherently complex due to the intricate interplay between PPI (parallel programming interface) strategies, SBC architectural characteristics, and application characteristics and constraints. To our knowledge, no solution presents a combined discussion of these three aspects. To tackle this problem, this article aims to provide a benchmark of the best-suited parallelism PPIs given a set of hardware and application characteristics and requirements. Compared to existing benchmarks, we introduce new metrics, additional applications, various parallelism interfaces, and extra hardware devices. Therefore, our contributions are the methodology to benchmark parallelism on SBCs and the characterization of the best-performing parallelism PPIs and strategies for given situations. We are confident that parallel computing will be mainstream to process edge and fog computing; thus, our solution provides the first insights regarding what kind of application and parallel programming interface is the most suited for a particular SBC hardware.

P-725 Automated follicular tracking with three-dimensional ultrasound and SonoAVC saves costs: debunking myths

Abstract Study question What is the incremental cost per patient and the budgetary impact of the SonoAVCTMfollicle technique compared to two-dimensional ultrasound in a private assisted reproduction center? Summary answer Our results support the implementation of follicular tracking with 3D ultrasound and SonoAVCTM from an economic point of view. What is known already Advantages of follicular tracking with 3D US and SonoAVC include increased precision and reproducibility, increased patient comfort, decreased ultrasonographer’s time and improved workflow. The main benefit of SonoAVC is that it allows quick measurements of follicular volume, which has been shown to be more precise than 2D diameters for estimation of follicular size. Until now, it has been assumed that 3D ultrasound represents an increase in costs, this being the main justification of professionals who refuse to implement it. Study design, size, duration Cost study and economic analysis. The costs associated with the adoption of the SonoAVC™follicle software and the 2D ultrasound were estimated as well as the cost of medical dedication time. Since the cost of the equipment represents an initial investment, we proceeded to annualize it. For the economic analysis we calculated a) cost for each patient included in the study and b) total annual cost for a private center to incorporate the SonoAVC™follicle program. Participants/materials, setting, methods Population: patients treated in our center in 2019 (N = 295). Budget impact analysis was performed from the perspective of a private assisted reproduction center with a 5-year time horizon. The analysis was adapted to three scenarios according to the size of the center: a private center with: a) 600 cycles/year including IVF/ICSI and oocyte donation b) 300 cycles/year and c) 100 cycles/year. Main results and the role of chance Equivalent annual cost of the ultrasound device and transvaginal probe after annualization was 3985.93 € for 2D and 4572.10 € for 3D. The corresponding cost per patient/cycle was 13,51€ for 2D and 15,50 € 3D. Medical dedication time cost was 5,6 € for 2D follicular monitoring and 3,3 € for 3D follicular monitoring. Total cost per patient/cycle for follicular monitoring, including hardware and medical dedication was 69,5€ for 2D and 48,5€ for 3D ultrasound. For the budget impact analysis, three different sizes of centers were considered: 600, 300 and 100 cycles/year. In all of them there was a saving with 3D ultrasound of 2101 €, 6303 € and 12606 € respectively. The net budgetary impact over 5 years, i.e., the difference between the current scenario (2D ultrasound) and the new scenario (3D ultrasound with SonoAVC™follicle) for a center with approximately 300 cycles/year, would be 31.515€. Therefore, the implementation of the new technique with SonoAVC™follicle would save costs. Limitations, reasons for caution In centers 600 cycles/year an extra ultrasound device may be included in the analysis. Wider implications of the findings Follicular monitoring with 3D ultrasound is cheaper than 2D ultrasound even in small centers and this saving is greater the larger the center is. Therefore, our results demonstrate that cost savings are another added advantage of follicular monitoring with 3D ultrasound and sonoAVC. Trial registration number not applicable

Rotor speed signature analysis‐based inter‐turn short circuit fault detection for permanent magnet synchronous machines

AbstractA rotor speed signature analysis‐ (RSSA‐)based inter‐turn short circuit (ITSC) fault diagnostic method is proposed, which is robust with regard to speed‐ and current‐loop bandwidths of permanent magnet synchronous machine (PMSM) drive systems. Conventional ITSC fault detection solutions that rely on current signals or extra devices. Thus, an initial step of investigation on the validity of RSSA is taken for residual insulation capacity monitoring of the ITSC fault at the incipient stage. The Vold–Kalman filtering order tracking method is employed for the real‐time extraction of fault features. Besides, the impact of speed‐ and current‐loop controller bandwidths on ITSC fault diagnosis is also analysed and an Adaline estimator is designed to decouple their impacts. Finally, the effectiveness of the proposed method is verified on a faulty PMSM, which exhibits satisfying results in tracking the degradation of residual insulation, even if the phase currents are significantly distorted due to low switching frequency of the inverter.

The Playhouse Effect: John Webster, Deixis and Story-Telling in the Theatres of Jacobean London

Unmarried mothers and children born out of wedlock are notoriously absent from the Carolean stage, which, on the other hand, saw an abundance of rakish gallants and prostitutes populating sexually charged plots. It is not a coincidence that the only two plays premiered between the 1660s and 1700 featuring an unmarried woman with a live child come up precisely with the arrival of William and Mary. This paper analyses the ways in which these plays—The Squire of Alsatia (1688) by Thomas Shadwell, and The Marriage-Hater Matched (1692) by Thomas Durfey—use the unmarried mother to convey a moral message that echoed William and Mary’s project of moral reform. However, these women are portrayed in radically different ways in both comedies. Although she takes a customary position of scorn in The Squire, the unmarried mother gets to be a good-hearted heroine that is eventually redeemed in The Marriage-Hater, a very challenging position for Durfey to portray which required of intra and extra textual devices to support her redemption without appearing to condone vice.

Low complexity on-board vector calibration network for optimal microwave wireless power transmission and enhanced RF-to-DC conversion efficiency

A low complexity on-board vector calibration network for optimal microwave wireless power transmission (MWPT) efficiency is proposed in this work. The proposed technique is based on sequentially tracking the minimum power level of two antenna elements in an array for both phase and amplitude error discrimination. Unlike conventional vector calibration networks based on a down-conversion topology, the proposed architecture can perform vector calibration by only monitoring the magnitude of each antenna element. Thus, high system efficiency can be achieved by reducing hardware costs and eliminating any unnecessary power consumption by extra active devices. Further, phase and amplitude imbalances between antenna elements in an array can be accurately captured with higher precision compared to the conventional rotating-element electric-field vector (REV) method. The proposed technique achieved higher resolutions for both amplitude and phase error detection than REV, which suffers from low resolution near the maximum or minimum field crests. To verify the MWPT efficiency improvement based on the proposed calibration network, a 1 × 4 phased array MWPT system was fabricated and tested at 5.8 GHz with a reference rectenna. With the calibrated power transmission, the total RF-DC conversion efficiencies at ± 45° beamforming angles were improved by up to a maximum of 138.79%.

Early Heart Disease Diagnosis Method Based On KNN

Heart disease is a health problem of wide concern around the world. This paper aims to realize an early prediction of heart disease based on k-nearest neighbors algorithm to warn the users of their potential risks of heart disease in an early stage so that measures can be taken to minimize the danger. The dataset introduced contains basic information of body that is possibly related to heart disease, with 14 feature dimensions and 303 samples in total. To realize the proposition of early prediction, three different strategies for feature dimension choosing are introduced to evaluate the predictions based on all the data, data that can be measured at home with household devices and data that do not require any extra measurements and devices. Several indexes are introduced to evaluate and compare the performance of the models that are trained and the changes caused by the decrease of feature dimensions are analyzed. Finally, possible future work for improving the models is discussed.

A simple technical innovation to prevent needle stick injuries among dental professionals.

Dental healthcare personnel face the potential danger of being exposed to infectious patients while administering local anesthesia injections during dental operations. This could lead to unintentional transfer of infectious diseases from patients to physicians. Although safety measures such as the One-hand-scoop technique and the use of safety syringes, plastic needle cap holders, and needles with safety caps are in place, there have been instances of needle stick injuries reported in clinics. This might be due to the lack of adherence to conventional safety measures or the impracticality of safety techniques and safety syringes. This article aims to demonstrate the utilization of dental tweezers, specifically London College tweezers or dental forceps, for the secure recapping of needles, eliminating the requirement for extra equipment or devices. After obtaining ethical approval (Approval No.: 024-01-2024) from the College of Dentistry, Dar Al Uloom University, 67 dental professionals, with consent for participation in the study, were included. They were requested to use dental tweezers/London College tweezers and dental extraction forceps such as maxillary anterior, mandibular anterior, and maxillary bayonet root forceps individually to recap the local anesthetic needles. The efficacy of these techniques was evaluated against the one-hand scoop technique for its ease, convenience, and reliability in preventing needle stick injuries. The evaluation of dental professionals regarding the ease of using dental tweezers to recap needles, compared to the one-hand scoop technique (p=0.592), maxillary bayonet root forceps (p=0.746), mandibular anterior forceps (p=0.380), and maxillary anterior forceps (p=0.808), did not yield statistically significant results. The assessment of the procedural simplicity of the one-hand scoop technique showed a satisfaction rate of over 40%, whereas the application of dental tweezers resulted in a satisfaction rate of 30%. However, the use of dental tweezers for needle recapping resulted in a satisfaction rate of over 50%, compared to a satisfaction rate of 30% for the one-handed scoop technique. There is no statistically significant difference in the assessment of the efficacy of dental tweezers and the one-hand scoop technique, bayonet root forceps, mandibular anterior forceps, maxillary anterior forceps, and dental tweezers for the needle capping technique. Therefore, dental forceps can be used instead of the one-handed scoop approach. The needle recapping procedure outlined in our study, aimed at preventing needle stick injuries, is simple to implement, and all dental specialties have convenient access to the required instruments.

A review on artificial intelligence and machine learning used in pharmaceutical research

The cutting-edge upward push of artificial intelligence and system mastering has been of considerable size. It has reduced the human workload move forward exceptional of life exceptionally. This article describes using artificial intelligence and system learning to augment drug discovery and upgrade to lead them to more well organised and correct. In medication, specialties in which images are vitally important, like radiology, pathology or oncology, have seized the able to be done and full-size efforts in studies and development were deployed to switch the adaptness of AI to scientific packages. With AI becoming a extra widespread device for usual scientific imaging evaluation duties, together with prognosis, segmentation, or classification, the important thing for a secure and efficient use of medical AI packages. This body of work supported the jobs of system gaining knowledge of and synthetic intelligence in facilitating drug expansion and finding out methods, making them greater cost-powerful or altogether casting off the want for clinical trials, as a result of the potential to conduct simulations the usage of those technologies. Doing so will assist in separating wish from hype and lead to knowledgeable choice making at the top-quality use of AI/ML in drug development. Machine studying strategies can subterfuge complicated analyzes with huge, heterogeneous, and excessive dimensional information collections without a guide enter, which has proved helpful inside the writing commercial enterprise applications. Combining system mastering, particularly deep getting to know, with human skill and revel in is probably the great manner to coordinate numerous significant facts stores. The magnificent facts-mining capacity of AI innovation has given new essentiality to computer supported medication plans that incorporate more than one clinical concerns are higher than piecemeal data.

Finding women in fishing communities around Lake Victoria: "Feasibility and acceptability of using phones and tracking devices".

Women in fishing communities have both high HIV prevalence and incidence, hence they are a priority population for HIV prevention and treatment interventions. However, their mobility is likely to compromise the effectiveness of interventions. We assessed the acceptability, feasibility and of using phones and global positioning system (GPS) devices for tracking mobility, to inform future health research innovations. A mult-site formative qualitative study was conducted in six purposively selected Fishing Communities on the shores of Lake Victoria in Kenya, Tanzania, and Uganda. Participants were selected based on duration of stay in the community and frequency of movement. Sixty-four (64) women participated in the study (16 per fishing community). Twenty-four (24) participants were given a study phone; 24 were asked to use their own phones and 16 were provided with a portable GPS device to understand what is most preferred. Women were interviewed about their experiences and recommendations on carrying GPS devices or phones. Twenty four (24) Focus Group Discussions with 8-12 participants were conducted with community members to generate data on community perceptions regarding GPS devices and phones acceptability among women. Data were analyzed thematically and compared across sites/countries. Women reported being willing to use tracking devices (both phones and GPS) because they are easy to carry. Their own phone was preferred compared to a study phone and GPS device because they were not required to carry an additional device, worry about losing it or be questioned about the extra device by their sexual partner. Women who carried GPS devices suggested more sensitization in communities to avoid domestic conflicts and public concern. Women suggested changing the GPS colour from white to a darker colour and, design to look like a commonly used object such as a telephone Subscriber Identity Module (SIM) card, a rosary/necklace or a ring for easy and safe storage. Women in the study communities were willing to have their movements tracked, embraced the use of phones and GPS devices for mobility tracking. Devices need to be redesigned to be more discrete, but they could be valuable tools to understanding movement patterns and inform design of interventions for these mobile populations.

A Soft, Adhesive Self-Healing Naked-Eye Strain/Stress Visualization Patch.

Learning about the strain/stress distribution in a material is essential to achieve its mechanical stability and proper functionality. Conventional techniques such as universal testing machines only apply to static samples with standardized geometry in laboratory environment. Soft mechanical sensors based on stretchable conductors, carbon-filled composites, or conductive gels possess better adaptability, but still face challenges from complicated fabrication process, dependence on extra readout device, and limited strain/stress mapping ability. Inspired by the camouflage mechanism of cuttlefish and chameleons, here an innovative responsive hydrogel containing light-scattering "mechano-iridophores" is developed. Force induced reversible phase separation manipulates the dynamic generation of mechano-iridophores, serving as optical indicators of local deformation. Patch-shaped mechanical sensors made from the responsive hydrogel feature fast response time (<0.4 s), high spatial resolution (≈100µm), and wide dynamic ranges (e.g., 10-150% strain). The intrinsic adhesiveness and self-healing material capability of sensing patches also ensure their excellent applicability and robustness. This combination of chemical and optical properties allows strain/stress distributions in target samples to be directly identified by naked eyes or smartphone apps, which is not yet achieved. The great advantages above are ideal for developing the next-generation mechanical sensors toward material studies, damage diagnosis, risk prediction, and smart devices.

Enhancing polarization 3D facial imaging: overcoming azimuth ambiguity without extra depth devices.

Polarization 3D imaging has been a research hotspot in the field of 3D facial reconstruction because of its biosafety, high efficiency, and simplicity. However, the application of this technology is limited by the multi-valued problem of the azimuth angle of the normal vector. Currently, the most common method to overcome this limitation is to introduce additional depth techniques at the cost of reducing its applicability. This study presents a passive 3D polarization facial imaging method that does not require additional depth-capturing devices. It addresses the issue of azimuth ambiguity based on prior information about the target image's features. Specifically, by statistically analyzing the probability distribution of real azimuth angles, it is found that their quadrant distribution is closely related to the positions of facial feature points. Therefore, through facial feature detection, the polarized normal azimuth angle of each pixel can be accurately assigned to the corresponding quadrant, thus determining a precise unique normal vector and achieving accurate 3D facial reconstruction. Finally, our azimuth angle correction method was validated by simulated polarization imaging results, and it achieved accurate correction for over 75% of the global pixels without using additional depth techniques. Experimental results further indicate that this method can achieve polarization 3D facial imaging under natural conditions without extra depth devices, and the 3D results preserve edge details and texture information.

Dosage Forms Suitability in Pediatrics: Acceptability of Antibiotics in a German Hospital.

Although drug acceptability can have a significant impact on patient adherence in pediatric therapy, data are limited, even for common therapeutic areas. We present the second part of an acceptability study conducted at the University Children's Hospital Düsseldorf, Germany. The study investigated the acceptability of most commonly used antibiotics in a pediatric hospital setting. The researchers used the acceptability reference framework to score the acceptability of five antibiotics based on 150 real-life observer reports of medicine intake. Four antibiotics assessed in this study were formulated as preparations for injection (ampicillin, ampicillin/sulbactam, ceftriaxone, and gentamicin) and one as a powder for oral liquid suspension (co-amoxiclav). All the antibiotics formulated as preparations for injection were rated negatively due to high rates of negative reactions (80%), the use of restraint (51%), the use of extra devices (99%), and long preparation and administration times (100%). The antibiotic formulated as a powder was significantly more well accepted. The study concluded that there is a lack of appropriate formulations for antibiotics for use in children. These findings are important in improving knowledge on acceptability drivers and might help in formulating and prescribing better medicines for children. The study highlights the need for healthcare professionals to have knowledge about the acceptability of different products to select the best-adapted product for each patient.

Smartphone photography based determination of refractive index of liquid

A simple but useful method is presented to measure the refractive index of a liquid using the smartphone camera. We have measured the image lengths by utilizing the ImageMeter application (free online) and determine the refractive index directly. We mention some striking points based upon which this simple method can be considered robust and novel: (i) no extra device other than the smartphone is required; (ii) there is no need to know the focal length of the camera lens of the smartphone; (iii) instead of finding the size of the object, only the image sizes of the object in different conditions are to be measured in pixel units to determine the refractive index of the liquid.

Enhancing real-time nonintrusive occupancy estimation in buildings via knowledge fusion network

Real-time nonintrusive occupancy estimation can maximize the use of existing sensors to infer occupant information in buildings with the advantages of fewer privacy concerns and fewer extra device costs. Recently, many deep learning architectures have proven effective in estimating occupancy directly from raw sensor data. However, some handcrafted features manually extracted from statistical and temporal domains might convey additional information for occupancy estimation. In this study, a novel knowledge fusion network for nonintrusive occupancy estimation is proposed to integrate knowledge from two streams, i.e. automatic knowledge stream from a deep learning architecture and handcrafted knowledge stream from manual feature engineering. Moreover, four different fusion modules are investigated to optimize the design of the fusion network. To verify the effectiveness of the proposed network, experiments are conducted in a dataset from the ASHRAE Global Occupant Behavior Database, which is collected from an office space with records of indoor environment parameters, occupant-building interactions, and contextual information. The results demonstrate the superiority of the proposed fusion network, which outperforms five representative algorithms. Furthermore, the ablation study underscores the benefits of knowledge fusion and occupant-building interaction information, showing that the proposed fusion network can enhance the occupancy estimation accuracy by 3.47 % to 9.24 %.

Effect of fibrinogen concentrate on the initial fibrinogen level in trauma and postpartum hemorrhage.

Massive hemorrhage is a serious event that threatens the lives of patients. Fibrinogen concentrate (FC) can control bleeding without causing viral complications and without volume loading, which can happen in transfusion-associated circulatory overload and transfusion-associated acute lung injury. FC application is easy and does not require dissolution or extra devices. It is a cost-effective agent when considering the blood and products used in large quantities. A total of 67 postpartum hemorrhage (PPH) and trauma patients' medical records, who had ASA I-III classification (The American Society of Anesthesiologists classification of physical status), were obtained. Patients were divided into two groups (fibrinogen level ≤ 100 mg/dl and ≥ 101 mg/dl). The following information was obtained from patient files: demographic parameters, history of operations, and laboratory findings (i.e., complete blood counts, coagulation tests, and fibrinogen levels). Also, the duration of intensive care unit stays and mechanical ventilation application days, the administration of fresh frozen plasma (FFP), erythrocytes, platelets, and FC numbers, and tranexamic acid infusion were recorded. There was no mortality in PPH patients in either group (fibrinogen level ≤ 100 mg/dl and ≥ 101 mg/dl). The mortality rate in trauma patients was significantly higher in the group with fibrinogen levels ≤ 100. A total of 170 g of FC were given to PPH patients and 92 g to trauma patients. There were statistically significant differences between the preoperative PT (prothrombin time), postoperative APTT (activated partial thromboplastin time), postoperative PT, and postoperative INR (international normalized ratio) levels of the patients in the group with fibrinogen levels ≤ 100. Mortality rates were also significantly higher, and hospital stays significantly longer in trauma patients in the group with fibrinogen levels ≤ 100. Therapy may be considered during massive bleeding and transfusion, as it can help to increase fibrinogen levels quickly and efficiently. Compared with FFP, fibrinogen concentrate may have some advantages in reducing the risk of fluid overload. FFP contains a range of clotting factors, including fibrinogen. It also contains other proteins and fluids that can lead to fluid overload, especially when given in large volumes during massive transfusions.