Exposure Of Adult Population Research Articles

Urinary Biomonitoring for Detection of As and Cd Exposure in Adult Population - A Cross Sectional Study from Selected Area of West Bengal, India

Urinary Biomonitoring for Detection of As and Cd Exposure in Adult Population - A Cross Sectional Study from Selected Area of West Bengal, India

Occurrence and Dietary Exposure of Adult Population to Phthalates in Hong Kong

This study aimed (1) to determine the levels of seven phthalates including Di-Ethyl Phthalate (DEP), Di-n-Butyl Phthalate (DnBP), Butyl Benzyl Phthalate (BBzP), Di-(2-Ethylhexyl) Phthalate (DEHP), Di-n-Octyl Phthalate (DnOP), Di-isononyl Phthalate (DiNP) and Di-isodecyl Phthalate (DiDP) in selected foods that are commonly consumed in Hong Kong as well as foods those are reported to be adulterated with phthalates; (2) to estimate the dietary exposure to phthalates of the Hong Kong adult populations at territory-wide scale; and (3) to assess the health risk associated with the exposure. Total Diet Study (TDS) approach was used to assess the associated health risk to the local people. Among the seven phthalates examined, DEHP was the most commonly detected phthalate, followed by DiNP, DnBP, BBzP, DiDP, DEP and DnOP. The maximum detected levels were found to be 23, 43, 93, 560, 3,500, 3,800 and 7,900 µg kg-1 for DnOP, DEP, BBzP, DnBP, DEHP, DiDP and DiNP respectively. It is believed that elevated levels of phthalates detected in isolated samples were more related to chemical nature of the food substrates. Food contact materials used in food manufacturing and packaging may also explain the situation. This study estimated that the dietary exposures to seven phthalates analyzed in the average adult consumer population ranged from a low of 0.098 μgkg-bw-1 day-1 for DnOP (upper bound) to a high of 4.8 μgkg-bw-1 day-1 in the case of DiNP. The exposure to both average and high consumers (95th percentile, or P95) of the adult populations were well within the corresponding Health-Based Guidance Values (HBGVs) for individual phthalate (maximum 13% of HBGVs). Furthermore, no age-sex population sub-group exceeded their respective HBGVs. The findings indicate that dietary exposures to seven phthalates analyzed in this study were unlikely to pose an unacceptable health risk to the Hong Kong population. The food group cereal and its products was the major contributor for DnBP, BBzP, DEHP, DnOP and DiNP dietary exposure, while non-alcoholic drinks and poultry were the major contributors for DEPs and DiDPs, respectively.

Evaluation of the effect of an environmental management program on exposure to manganese in a mining zone in Mexico

BackgroundIn the state of Hidalgo, Mexico, is found the largest second deposit of Manganese (Mn) in Latin America. Various studies on the sources of emission, exposure, and the effects on the health of children and adults have been conducted utilizing an ecosystem approach. Given the findings of Mn levels in air and the neurocognitive effects, an Environmental Management Program (EMP) was designed and implemented with the purpose of reducing exposure to Mn of the population, including various actions for reducing Mn emissions into the atmosphere. ObjectiveTo evaluate the impact of the EMP on the concentrations of Mn in air, as well as the modification of exposure to Mn in the blood and hair of adult residents of the communities intervened. MethodsA quasi-experimental study was conducted in five rural communities, in which Mn concentrations were evaluated in air and in blood in the years 2002 and 2007, pre-intervention, and in 2013, postintervention. In 2003, the concentration of hair Mn among the communities was evaluated. Measurements were carried out of Particulate Matter (PM) of >10 and 2.5μm (PM10 and PM2.5), and Mn in PM10 and PM2.5 were measured using proton-induced X-ray emissions (PIXE). The method of Difference in Differences (DID) was applied to estimate the impact of EMP on Mn concentrations in particulate matter via linear regression through multilevel models. To evaluate the effect of Mn concentrations in air over Mn concentrations in blood in both study periods in the mining communities per year (2002 and 2013), a linear regression model for each year was employed. ResultsWe estimated that the EMP contributed to reducing the average daily concentrations of Mn in PM10 and PM2.5 by 92 and 85%, respectively. The adjusted model did not show an effect of Mn concentrations in air over Mn concentrations in blood in both study periods. ConclusionsThe results suggest that the measures implemented to reduce Mn emissions in air exerted a significant impact on the reduction of inhaled exposure in adult population.

Aflatoxin M1 in processed milk and infant formulae and corresponding exposure of adult population in Serbia in 2013–2014

Aflatoxin M1 (AFM1) occurrence was analysed in 80 samples of milk and 21 samples of infant formulae on the Serbian market, using high-performance liquid chromatography with fluorescence detection. All milk samples collected in 2013 showed AFM1 contamination in the range 0.02–0.32 μg kg−1, with a mean level of 0.13 μg kg−1. The EU maximum level for AFM1 in milk (0.05 μg kg−1) was exceeded in 75% of the samples. In 2014, AFM1 was found in 83%, 70%, 80% and 58% of the samples collected in April, July, September and December, respectively, exceeding the limit in 5% of the samples taken in July. The additional number of liver cancer cases per year associated with exposure to AFM1 was estimated to be 0.004 in the adult population. Regarding infant formulae, AFM1 was found in only one sample.

Risk Factors for Lead Exposure in Adult Population in Southern Brazil

In Brazil there is no systematic evaluation to access blood lead levels (BLL) in the general population and few studies with adults have been published. The aim of this study was to examine the socioeconomic, environmental, and lifestyle determinants of BLL in the adult Brazilian population. In total, 959 adults, aged 40 years or more, were randomly selected in a city in southern Brazil. Information on socioeconomic, dietary, lifestyle, and occupational background was obtained by interviews. A spatial analysis was conducted to discern whether there were any identifiable sources of exposure. BLL were measured by inductively coupled plasma–mass spectrometry. There was an adjustment for gender, age, race, education, income class, smoking status, alcohol consumption, occupation, and red meat or cow milk consumption (Model 1), and for occupation and gender (Model 2). The geometric mean of BLL was 1.97 μg/dl (95% CI: 1.9–2.04 μg/dl). In Model 1, BLL were positively associated with male gender, older age, and drinking and smoking habits, and less frequently with milk consumption. In Model 2, data showed higher BLL in non-white than white participants, in former smokers and individuals with current or former employment in lead (Pb) industries. The participants living in the area with more Pb industries had higher BLL (3.3 μg/dl) compared with those residing in other areas with no or fewer Pb industries (1.95 μg/dl). Despite the low BLL found in adults living in an urban area, Pb industries need to be monitored and regulatory laws implemented to prevent metal contamination in urban settings.

Risk Factors for Lead Exposure in Adult Population in Southern Brazil

Risk Factors for Lead Exposure in Adult Population in Southern Brazil